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71687
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Showing 1-30 of 2363 results for "71687" within Papers
Nanomedicine (London, England), 10(10), 1539-1553 (2015-05-27)
This study aimed to investigate the effects of actively targeting mesoporous silica nanoparticles (MSNPs) toward mammalian sperm with a cell-penetrating peptide (C105Y), with subsequent analysis of binding rates and nano-safety profiles. Boar sperm were exposed in vitro to C105Y-functionalized MSNPs
Journal of chromatography. A, 1361, 23-33 (2014-08-31)
This paper reports a nanomagnetic polyhedral oligomeric silsesquioxanes (POSS)-directing strategy toward construction of molecularly imprinted hybrid materials for antibiotic residues determination in milk samples. The imprinted polymeric layer was facilely obtained through the copolymerization of active vinyl groups present on
Small (Weinheim an der Bergstrasse, Germany), 11(2), 195-201 (2014-08-15)
Au-Cu2 O core-shell nanocubes, octahedra, and rhombic dodecahedra display facet-dependent optical properties. Furthermore, different-sized Au-Cu2 O octahedra with 58, 65, 68, and 73 nm octahedral gold cores clearly show a transition from the shell thickness-independent gold surface plasmon resonance band
BMC veterinary research, 11, 282-282 (2015-11-15)
Cats with feline calicivirus (FCV)-related symptoms are commonly presented to veterinary practitioners. Various clinical manifestations have been attributed to FCV, i.e. upper respiratory tract disease (URTD), oral ulcerations, gingivostomatitis, limping syndrome and virulent systemic disease. Additionally, healthy cats can shed
Journal of cellular biochemistry, 116(10), 2270-2282 (2015-04-01)
Sar1B GTPase is a key component of Coat protein complex II (COPII)-coated vesicles that bud from the endoplasmic reticulum to export newly synthesized proteins. The aims of this study were to determine whether Sar1B responds to lipid regulation and to
Journal of environmental sciences (China), 25(4), 637-644 (2013-08-09)
Organic phosphorus (nonreactive P, NRP) is a major component of P in sediments, but information about its chemical forms and dynamic transformation is limited. The chemical forms and dynamic behaviors of NRP in a sediment profile from Lake Taihu, a
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 40(7), 671-682 (2015-06-04)
This study tested the hypothesis that elevating the intracellular phosphorylation potential (IPP = [ATP]/[ADP]free) within rat fast-twitch tibialis anterior muscles by creatine (Cr) loading would prevent fast-to-slow fibre transitions induced by chronic low-frequency electrical stimulation (CLFS, 10 Hz, 12 h/day).
The Science of the total environment, 527-528, 520-529 (2015-05-26)
This study examined the feasibility of nanofiltration (NF) and reverse osmosis (RO) in treating challenging natural tropical waters containing high fluoride and natural organic matter (NOM). A total of 166 water samples were collected from 120 sources within northern Tanzania
Journal of chromatography. A, 1394, 137-147 (2015-04-08)
Extraction parameters, chemical fingerprint, and the single compounds' activity levels were considered for the selection of active botanicals. For an initial survey, the total bioactivity (i.e., total reducing capacity, total flavonoids contents and free radical scavenging capacity) of 21 aqueous
Tuberculosis (Edinburgh, Scotland), 95(6), 770-779 (2015-09-01)
Dormant, slow-growing, antibiotic-tolerant Mycobacterium tuberculosis undermine the shortening of tuberculosis treatment to less than 6 months and are thought to be characterised by intracellular lipid bodies. Antibiotic effects on such persisting bacilli escape evaluation as they cannot be readily cultured.
Mutation research. Genetic toxicology and environmental mutagenesis, 786-788, 137-143 (2015-07-28)
As a part of the Japanese Center for the Validation of Alternative Methods (JaCVAM)-initiative international validation study of the in vivo alkaline comet assay (comet assay), we examined DNA damage in the liver, stomach, and bone marrow of rats dosed
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 50(10), 1040-1045 (2015-06-30)
This study evaluates the potential for a novel semidecentralized approach that uses coagulant disinfectant products (CDPs) for humanitarian water treatment, by testing two commercially available products (CDP-W and CDP-T). Their performances were evaluated against the relevant water quality treatment objectives
Nature communications, 6, 7899-7899 (2015-08-15)
Interactions between absorbers and plasmonic metasurfaces can give rise to unique optical properties not present for either of the individual materials and can influence the performance of a host of optical sensing and thin-film optoelectronic applications. Here we identify three
Journal of pharmaceutical sciences, 104(10), 3351-3365 (2015-06-26)
The development of novel systems with oral protein delivery as ultimate goal represents an important field of pharmaceutics. Prilling of protein-loaded polymeric solutions into lipid-based hardening baths could provide here an attractive formulating technology. As the obtained microgel dispersion can
Molecular pharmacology, 88(6), 1002-1010 (2015-10-03)
Many spider-venom peptides are known to modulate the activity of the voltage-gated sodium (NaV) subtype 1.7 (NaV1.7) channel, which has emerged as a promising analgesic target. In particular, a class of spider-venom peptides (NaSpTx1) has been found to potently inhibit
AAPS PharmSciTech, 16(2), 444-454 (2014-11-02)
The objective of the present study was to investigate the effects of processing variables and formulation factors on the characteristics of hot-melt extrudates containing a copolymer (Kollidon® VA 64). Nifedipine was used as a model drug in all of the
Organic & biomolecular chemistry, 13(2), 388-397 (2014-11-05)
In the development of our melanoma-selective delivery approach, three preselected conjugates of 5-iodo-2'-deoxyuridine (IUdR) to the ICF01012 melanoma-carrier were radiolabelled with iodine-125, and their in vivo distribution profile was determined. A radioiodination method for the conjugate 1a and its PEGylated
Human reproduction (Oxford, England), 30(4), 800-811 (2015-03-06)
Does ulipristal acetate (UPA) used for emergency contraception (EC) interfere with the human embryo implantation process? UPA, at the dosage used for EC, does not affect human embryo implantation process, in vitro. A single pre-ovulatory dose of UPA (30 mg)
Pharmacological research, 91, 78-87 (2014-12-08)
The ability of an antineoplastic drug to exert its cytostatic effect depends largely on the balance between its uptake into and extrusion from the cancer cells. ATP driven efflux transporter proteins drive the export of antineoplastic drugs and play a
Development and evaluation of electromembrane extraction across a hollow polymer inclusion membrane.
Journal of chromatography. A, 1406, 34-39 (2015-07-05)
In this work, a new variation of the electromembrane extraction (EME) approach employing a hollow polymer inclusion membrane (HPIM) was developed. In this method, a HPIM was prepared by casting a solution of the desired proportions of cellulose acetate (CTA)
Luminescence : the journal of biological and chemical luminescence, 30(7), 990-995 (2015-02-03)
The chemiluminescence (CL) of lucigenin (Luc(2+)) can be enhanced by different alcohols in alkaline solution. The effect of different fatty alcohols on the CL of lucigenin was related to the carbon chain length and the number of hydroxyl groups. Glycerol
Drug delivery and translational research, 4(3), 268-274 (2015-03-20)
Amorphous indomethacin was prepared by melting the γ-form of indomethacin, spatially confined within microcontainers (inner diameter of 223 μm), followed by cooling of the melt at a rate of 14, 23 or 36 K/min. The physical stability of the amorphous indomethacin within
The Analyst, 140(2), 590-599 (2014-11-27)
Development of improved glucose detection has vast significance in both clinical and point of care settings. Herein, we present a novel, label-free, enzyme-free, colorimetric method of glucose detection that relies on the reduction of a gold salt precursor facilitated by
BMC genomics, 16, 442-442 (2015-06-10)
Amplified gene families on sex chromosomes can harbour genes with important biological functions, especially relating to fertility. The Y-linked heat shock transcription factor (HSFY) family has become amplified on the Y chromosome of the domestic pig (Sus scrofa), in an
Journal of food science, 80(10), C2117-C2126 (2015-09-17)
Mature-green cherry tomato fruits (Lycopersicon esculentum cv. Jinyu) were exposed to different power densities of ultrasound (66.64, 106.19, and 145.74 W/L) at 25 °C to study ultrasound non-thermal effects on the storage properties. Among the three levels of ultrasound irradiation
Journal of chromatography. A, 1366, 65-72 (2014-09-24)
A novel interface that enables high-performance anion-exchange chromatography (HPAEC) to be coupled with electrospray ionization (ESI) mass spectrometry (MS) is reported. A sheath liquid consisting of 50mM NH4Ac in isopropanol with 0.05% acetic acid, infused at a flow rate of
Talanta, 114, 243-247 (2013-08-21)
In the present work, a flow injection (FI) "turn off-on" chemiluminescent method was developed for the determination of glutathione (GSH). Strong chemiluminescence (CL) signals were observed from the hydrogen peroxide and CdTe quantum dots (QDs) system under basic condition, addition
Proceedings of the National Academy of Sciences of the United States of America, 112(34), E4792-E4801 (2015-08-12)
In ventricular myocytes, the physiological function of stromal interaction molecule 1 (STIM1), an endo/sarcoplasmic reticulum (ER/SR) Ca(2+) sensor, is unclear with respect to its cellular localization, its Ca(2+)-dependent mobilization, and its action on Ca(2+) signaling. Confocal microscopy was used to
Molecular pharmacology, 88(4), 676-688 (2015-07-16)
The serotonin transporter (SERT) regulates neurotransmission by the biogenic monoamine neurotransmitter serotonin (5-HT, 5-hydroxytryptamine) in the central nervous system, and drugs inhibiting SERT are widely used for the treatment of a variety of central nervous system diseases. The conformational dynamics
Carbohydrate polymers, 129, 216-223 (2015-06-09)
Viscoelastic properties of aqueous solutions of xyloglucan extracted from Hymenaea courbaril seeds (Jatobá gum) were investigated by rheology over a wide range of concentrations and temperatures. The polymer was characterized in dilute solutions by light scattering measurements and size exclusion
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