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Showing 1-30 of 1692 results for "733458" within Papers
Kevin Y Lee et al.
Nature communications, 6, 8054-8054 (2015-08-25)
Skeletal muscle is composed of both slow-twitch oxidative myofibers and fast-twitch glycolytic myofibers that differentially impact muscle metabolism, function and eventually whole-body physiology. Here we show that the mesodermal transcription factor T-box 15 (Tbx15) is highly and specifically expressed in
Christian Brion et al.
BMC genomics, 15, 1085-1085 (2014-12-17)
Thiamine availability is involved in glycolytic flux and fermentation efficiency. A deficiency of this vitamin may be responsible for sluggish fermentations in wine making. Therefore, both thiamine uptake and de novo synthesis could have key roles in fermentation processes. Thiamine
Daniel A Enquobahrie et al.
Reproductive sciences (Thousand Oaks, Calif.), 22(7), 904-910 (2015-02-14)
Repeat pregnancies with different perinatal outcomes minimize underlying maternal genetic diversity and provide unique opportunities to investigate nongenetic risk factors and epigenetic mechanisms of pregnancy complications. We investigated gestational diabetes mellitus (GDM)-related differential DNA methylation in early pregnancy peripheral blood
Shewit Kalayou et al.
Cell biology and toxicology, 30(6), 361-376 (2014-11-25)
The mycotoxin alternariol (AOH) is an important contaminant of fruits and cereal products. The current study sought to address the effect of a non-toxic AOH concentration on the proteome of the steroidogenic H295R cell model. Quantitative proteomics based on stable
Anna Della Corte et al.
Talanta, 140, 52-61 (2015-06-07)
The abundance of lipids in plants is influenced by genotype and phenotype. Despite being a very important class of plant metabolites, knowledge of grape lipids is still very limited to date, with the exception of those located in seeds. Few
Pamela Brunswick et al.
Journal of chromatography. A, 1405, 49-71 (2015-06-16)
A rapid and sensitive liquid chromatography quadrupole time of flight method has been established for the determination of total naphthenic acid concentrations in aqueous samples. This is the first methodology that has been adopted for routine, high resolution, high throughput
Wei-Chung Su et al.
Inhalation toxicology, 26(14), 843-852 (2014-10-08)
Workers and researchers in the carbon nanotubes (CNT)-related industries and laboratories might be exposed to CNT aerosols while generating and handling CNT materials. From the viewpoint of occupational health, it is essential to study the deposition of CNT aerosol in
Mieczysław Sajewicz et al.
Journal of chromatographic science, 52(4), 329-333 (2013-04-11)
Previous studies by the authors have used thin-layer chromatography to demonstrate the ability of chiral low molecular weight carboxylic acids to undergo spontaneous oscillatory chiral conversion in abiotic (aqueous and nonaqueous) solutions. General mechanisms of this conversion were proposed, taking
Michelle S Gupta et al.
Annals of biomedical engineering, 43(5), 1145-1157 (2014-11-12)
Intervertebral disc (IVD) herniation can be caused by both degeneration and traumatic injury, ultimately resulting in back pain or sciatica due to disc protrusion. Replacement of the nucleus pulposus (NP) tissue during surgical intervention post herniation could improve the long-term
Clayton B'Hymer et al.
Journal of chromatographic science, 53(4), 619-624 (2014-08-19)
A high-performance liquid chromatography-tandem mass spectrometric (HPLC-MS/MS) method was developed for the determination of mitomycin C, an anticancer drug, from contamination on various surfaces. Mitomycin C is often used in various forms of intraperitoneal chemotherapy, and operating room healthcare worker
Gisele H J M Leyten et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 21(13), 3061-3070 (2015-03-20)
Serum PSA (sPSA) testing has led to the identification of patients with indolent prostate cancer, and inevitably overtreatment has become a concern. Progensa PCA3 urine testing was shown to improve the diagnosis of prostate cancer, but its diagnostic value for
Henriette Jülke et al.
Cell transplantation, 24(6), 1111-1125 (2013-12-18)
The purpose of this study was to evaluate the use of three different superparamagnetic iron oxide (SPIO) particles for labeling of ovine and equine bone marrow (BM)-derived multipotent stromal cells (MSCs) in vitro. MSCs were obtained from five adult sheep
Masashi Kamikawa et al.
Acta histochemica et cytochemica, 47(2), 35-43 (2014-09-16)
We previously demonstrated that macrophages exhibit endoplasmic reticulum fragmentation under cholesterol-rich conditions, which results in the generation of acyl-coenzyme A: cholesterol acyltransferase 1 (ACAT1)-associated late endosomes/lysosomes (ACAT1-LE). ACAT1-LE efficiently esterify free cholesterol in loco, even with abnormal egress of free
Yueting Shao et al.
Toxicological sciences : an official journal of the Society of Toxicology, 146(1), 43-51 (2015-03-27)
The cerebellum is known as the major target regions of methylmercury (MeHg) toxicity, but the mechanisms are still not fully understood. We studied the effects of MeHg exposure in the cerebellum of common marmoset (Callithrix jacchus) using a shotgun proteomic
Jinzhou Yuan et al.
Lab on a chip, 15(13), 2790-2798 (2015-05-27)
Animal motility varies with genotype, disease, aging, and environmental conditions. In many studies, it is desirable to carry out high throughput motility-based sorting to isolate rare animals for, among other things, forward genetic screens to identify genetic pathways that regulate
M L Alves da Silva et al.
Journal of tissue engineering and regenerative medicine, 9(6), 714-723 (2013-10-25)
Paracrine signalling from chondrocytes has been reported to increase the synthesis and expression of cartilage extracellular matrix (ECM) by stem cells. The use of conditioned medium obtained from chondrocytes for stimulating stem cells chondrogenic differentiation may be a very interesting
Diogo Vieira da Silva Pellegrina et al.
PloS one, 10(6), e0128341-e0128341 (2015-06-06)
Sepsis is one of the highest causes of mortality in hospitalized people and a common complication in both surgical and clinical patients admitted to hospital for non-infectious reasons. Sepsis is especially common in older people and its incidence is likely
Charmion I Cruickshank-Quinn et al.
PloS one, 9(7), e101855-e101855 (2014-07-10)
Cigarette smoke exposure is linked to the development of a variety of chronic lung and systemic diseases in susceptible individuals. Metabolomics approaches may aid in defining disease phenotypes, may help predict responses to treatment, and could identify biomarkers of risk
Anita Aranyi et al.
Journal of chromatography. A, 1387, 123-133 (2015-02-18)
The direct separation of the enantiomers of 1-(α-aminoarylmethyl)-2-naphthol, 1-(α-aminoalkyl)-2-naphthol, 2-(α-aminoarylmethyl)-1-naphthol analogues and 2-(1-amino-2-methylpropyl)-1-naphthol) was investigated in supercritical fluid chromatography. Five commercially available chiral stationary phases based on immobilized polysaccharide chiral selectors (Chiralpak IA, IB, IC, ID and IE) were evaluated.
Bo Kyung Sun et al.
International journal of molecular sciences, 16(7), 16655-16668 (2015-07-25)
Fluoxetine was originally developed as an antidepressant, but it has also been used to treat obesity. Although the anti-appetite effect of fluoxetine is well-documented, its potential effects on human adipose-derived stem cells (ASCs) or mature adipocytes have not been investigated.
Evaluation of five antifungal agents used in remediation practices against six common indoor fungal species.
P Chakravarty et al.
Journal of occupational and environmental hygiene, 10(1), D11-D16 (2012-12-01)
Getu Kahsay et al.
Journal of pharmaceutical and biomedical analysis, 111, 91-99 (2015-04-17)
Misoprostol is a synthetic prostaglandin E1 analogue which is mainly used for prevention and treatment of gastric ulcers, but also for abortion due to its labour inducing effect. Misoprostol exists as a mixture of diastereoisomers (1:1) and has several related
Lorena Rocha Ayres et al.
The journal of venomous animals and toxins including tropical diseases, 21, 29-29 (2015-08-15)
Activation of the complement system plays an important role in the regulation of immune and inflammatory reactions, and contributes to inflammatory responses triggered by envenomation provoked by Bothrops snakes. The present study aimed to assess whether Bothrops jararacussu and Bothrops
Fang Wei et al.
Journal of chromatography. A, 1404, 60-71 (2015-06-14)
In this investigation, off-line comprehensive two-dimensional liquid chromatography-atmospheric pressure chemical ionization mass spectrometry using a single column has been applied for the identification and quantification of triacylglycerols in edible oils. A novel mixed-mode phenyl-hexyl chromatographic column was employed in this
Sara Tomei et al.
Molecular oncology, 9(1), 93-104 (2014-09-02)
The existence of a dichotomy between immunologically active and quiescent tumor phenotypes has been recently recognized in several types of cancer. The activation of a Th1 type of immune signature has been shown to confer better prognosis and likelihood to
Bikramjit Ghosh et al.
Marine biotechnology (New York, N.Y.), 17(6), 841-853 (2015-09-28)
This study examined the feasibility of alginate microcapsules manufactured using a low-impact technology and reagents to protect orally delivered immunogens for use as immunoprophylactics for fish. Physical characteristics and protein release kinetics of the microcapsules were examined at different pH
Philippe Régnier et al.
Marine drugs, 13(5), 2857-2874 (2015-05-12)
Astaxanthin, a powerful antioxidant, is a good candidate for the prevention of intracellular oxidative stress. The aim of the study was to compare the antioxidant activity of astaxanthin present in two natural extracts from Haematococcus pluvialis, a microalgae strain, with
Jae Won Jeong et al.
Nature communications, 5, 5387-5387 (2014-11-11)
Nanotransfer printing technology offers outstanding simplicity and throughput in the fabrication of transistors, metamaterials, epidermal sensors and other emerging devices. Nevertheless, the development of a large-area sub-50 nm nanotransfer printing process has been hindered by fundamental reliability issues in the replication
Noe Cabello et al.
American journal of physiology. Lung cellular and molecular physiology, 309(10), L1150-L1163 (2015-09-06)
Sex differences in the incidence of respiratory diseases have been reported. Women are more susceptible to inflammatory lung disease induced by air pollution and show worse adverse pulmonary health outcomes than men. However, the mechanisms underlying these differences remain unknown.
Byung-Man Kwak et al.
Food chemistry, 165, 569-574 (2014-07-21)
A rapid and simple sample preparation method for vitamin D3 (cholecalciferol) was developed for emulsified dairy products such as milk-based infant formulas. A sample was mixed in a 50 mL centrifuge tube with the same amount of water and isopropyl
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