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Showing 1-30 of 313 results for "741442" within Papers
Ryuichiro Suzuki et al.
Biochimica et biophysica acta, 1854(5), 476-484 (2015-03-04)
Starch and glycogen are widespread storage polysaccharides in bacteria, plants, and animals. Recently, some cyanobacteria were found to accumulate water-insoluble α-glucan similar to amylopectin rather than glycogen, the latter of which is more commonly produced in these organisms. The amylopectin-producing
Sabine H van Rijt et al.
ACS nano, 9(3), 2377-2389 (2015-02-24)
Nanoparticles allow for controlled and targeted drug delivery to diseased tissues and therefore bypass systemic side effects. Spatiotemporal control of drug release can be achieved by nanocarriers that respond to elevated levels of disease-specific enzymes. For example, matrix metalloproteinase 9
Noorhayati Idros et al.
Sensors (Basel, Switzerland), 15(6), 12891-12905 (2015-06-06)
This proof-of-concept study proposes a novel sensing mechanism for selective and label-free detection of 2,4,6-trinitrotoluene (TNT). It is realized by surface chemistry functionalization of silica nanoparticles (NPs) with 3-aminopropyl-triethoxysilane (APTES). The primary amine anchored to the surface of the silica
Celina Baravalle et al.
Research in veterinary science, 100, 52-60 (2015-04-14)
The purposes of this study were to explore TLR2 and TLR4 participation and MyD88 and NF-κB activation in bovine mammary glands (BMG) treated with Panax ginseng (PG) at involution and verify the effect of PG in the cytokine expression. Quarters
Lucía Vigezzi et al.
Reproductive toxicology (Elmsford, N.Y.), 52, 83-92 (2015-02-11)
We assessed the long-term effect of perinatal exposure to bisphenol A (BPA) on the rat uterus and the uterine response to estrogen (E2) replacement therapy. BPA (0.5 or 50μg/kg/day) was administered in the drinking water from gestational day 9 until
Dang-Dang Li et al.
Molecular and cellular endocrinology, 413, 13-25 (2015-06-27)
Although Hmgn3 is involved in the regulation of development and cellular differentiation, its physiological roles on decidualization are still unknown. Here we showed that Hmgn3 was highly expressed in the decidua and decidualizing stromal cells. Overexpression of Hmgn3 variants, Hmgn3a
Diego Soares Domingues et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 993-994, 26-35 (2015-05-20)
This study reports on the development of a rapid, selective, and sensitive column-switching liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to analyze sixteen drugs (antidepressants, anticonvulsants, anxiolytics, and antipsychotics) in plasma samples from schizophrenic patients. The developed organic-inorganic hybrid monolithic column
F S Ruggeri et al.
Nature communications, 6, 7831-7831 (2015-07-29)
Amyloids are insoluble protein fibrillar aggregates. The importance of characterizing their aggregation has steadily increased because of their link to human diseases and material science applications. In particular, misfolding and aggregation of the Josephin domain of ataxin-3 is implicated in
Yi Wang et al.
Biosensors & bioelectronics, 70, 61-68 (2015-03-22)
In this study, a sensitive immune-biosensing system capable of multiplexed, real-time electrical readout was developed based on giant magnetoresistive (GMR) sensor array to detect a panel of protein biomarkers simultaneously. PAPP-A, PCSK9, and ST2 have been regarded as promising candidate
Behzad Rezaei et al.
Biosensors & bioelectronics, 48, 61-66 (2013-05-08)
In this work, stainless steel (SS) was used as a substrate to fabricate an inexpensive and disposable impedimetric immunosensor. SS surface was modified with a stable thin layer of 3-aminopropyltriethoxysilane (APTES), and followed by electrodeposition of gold nanoparticles (GNPs). The
C A F Mançanares et al.
Theriogenology, 84(6), 887-898 (2015-07-06)
The yolk sac (YS) represents a promising source of stem cells for research because of the hematopoietic and mesenchymal cell niches that are present in this structure during the development of the embryo. In this study, we report on the
Benjamin Otto et al.
PloS one, 9(7), e102552-e102552 (2014-07-23)
Lymph node metastasis indicates poor prognosis in esophageal cancer. To understand the underlying mechanisms, most studies so far focused on investigating the tumors themselves and/or invaded lymph nodes. However they neglected the potential events within the metastatic niche, which precede
T P Vinod et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 15(14), 3026-3031 (2014-08-01)
Bottom-up synthesis offers novel routes to obtain nanostructures for nanotechnology applications. Most self-assembly processes are carried out in three dimensions (i.e. solutions); however, the large majority of nanostructure-based devices function in two dimensions (i.e. on surfaces). Accordingly, an essential and
Xinai Zhang et al.
Talanta, 132, 600-605 (2014-12-06)
In this paper, we report an amplified electrochemical immunoassay for Escherichia coli as indicator bacteria relevant to the quality of dairy product using the functionalized gold nanorod-based labels ({dAb-AuNR-FCA}). The {dAb-AuNR-FCA} labels were designed by exploiting silica-functionalized gold nanorods (AuNR@SiO2)
Margaret A Keighren et al.
Transgenic research, 24(4), 665-691 (2015-06-07)
Recent reports of a new generation of ubiquitous transgenic chimaera markers prompted us to consider the criteria used to evaluate new chimaera markers and develop more objective assessment methods. To investigate this experimentally we used several series of fetal and
Lian Bai et al.
Soft matter, 11(26), 5282-5293 (2015-06-09)
Bicontinuous, interfacially jammed, emulsion gels (bijels) are a novel class of materials composed of two immiscible phases with interpenetrating domains that are stabilized by a monolayer of colloidal particles at the interface. However, existing bijel systems so far all consist
Israel D de Souza et al.
Talanta, 140, 166-175 (2015-06-07)
The present study (1) reports on the synthesis of two hybrid silica monoliths functionalized with aminopropyl or cyanopropyl groups by the sol-gel process; (2) evaluates these monoliths as selective stationary phase for microextraction by packed sorbent (MEPS) to determine drugs
E Calleri et al.
Chembiochem : a European journal of chemical biology, 15(8), 1154-1160 (2014-05-07)
Resveratrol, a modulator of several signaling proteins, can exert off-target effects involving the peroxisome proliferator-activated receptor (PPAR) transcription factors. However, evidence for the direct interaction between this polyphenol and PPARs is lacking. Here, we addressed the hypothesis that resveratrol and
Yulan Wang et al.
Biosensors & bioelectronics, 74, 59-65 (2015-06-30)
An ultrasensitive sandwich-type electrochemical immunosensor based on a novel signal amplification strategy was developed for the quantitative determination of human immunoglobulin G (IgG). Pd nanocubes functionalized magnetic graphene sheet (Pd-Fe3O4-GS) was employed as the matrix to immobilize the primary antibodies
Robert Weinmeister et al.
ACS nano, 9(10), 9718-9730 (2015-09-15)
Aqueous microdroplets with a volume of a few femtoliters are an ideal sample size for single-molecule fluorescence experiments. In particular, they enable prolonged measurements to be made on individual molecules that can diffuse freely in the surrounding medium. However, the
Yilin Lu et al.
Physical chemistry chemical physics : PCCP, 17(33), 21149-21157 (2014-12-06)
A new type of surface-enhanced Raman scattering (SERS) substrate consisting of β-cyclodextrin (β-CD) coated SiO2@Au@Ag nanoparticles (SiO2@Au@Ag@CD NPs) has been achieved. Our protocol was a simplified approach as the fabrication and modification of the silver shell were realized in a
Liang Yang et al.
Archives of pharmacal research, 37(12), 1554-1559 (2014-08-15)
The present study aimed to develop an effective oral formulation of tranilast (TL), a poorly soluble anti-inflammatory drug, via the formation of drug complex with 3-aminopropyl functionalized magnesium phyllosilicate (AMP clay) and improve the pH-dependent drug dissolution and bioavailability of
Lorraine O'Neill et al.
Arthritis & rheumatology (Hoboken, N.J.), 67(9), 2447-2456 (2015-05-29)
Giant cell arteritis (GCA) is pathologically characterized by dysfunctional angiogenesis and inflammatory cell infiltration. Acute-phase serum amyloid A (A-SAA) is an acute-phase reactant, but is also produced at sites of inflammation and may contribute to vascular inflammation in atherosclerosis. This
K C Barick et al.
Dalton transactions (Cambridge, England : 2003), 44(33), 14686-14696 (2015-07-29)
Magnetic luminescent hybrid nanostructures (MLHN) have received a great deal of attention due to their potential biomedical applications such as thermal therapy, magnetic resonance imaging, drug delivery and intracellular imaging. We report the development of bifunctional Fe3O4 decorated YPO4:Eu hybrid
Sheng-Lin Cai et al.
Biosensors & bioelectronics, 71, 37-43 (2015-04-18)
In this work, we have proposed a label-free nanopore-based biosensing strategy for protein detection by performing the DNA-protein interaction inside a single glass conical nanopore. A lysozyme binding aptamer (LBA) was used to functionalize the walls of glass nanopore via
Simone Guedes Calderano et al.
Nucleic acids research, 43(5), 2655-2665 (2015-02-19)
Eukaryotic genome duplication relies on origins of replication, distributed over multiple chromosomes, to initiate DNA replication. A recent genome-wide analysis of Trypanosoma brucei, the etiological agent of sleeping sickness, localized its replication origins to the boundaries of multigenic transcription units.
Charles A P Godoy et al.
Clinics (Sao Paulo, Brazil), 70(5), 356-362 (2015-06-04)
The vulva is the primary site affected in lichen sclerosus, a chronic dermatosis in women that is histologically characterized by a zone of collagen remodeling in the superior dermis. The normal physiological properties of the vulva depend on the assembly
Dan Zheng et al.
Talanta, 99, 22-28 (2012-09-13)
A mediatorless glucose biosensor was developed by the immobilization of glucose oxidase (GOx) to graphene-functionalized glassy carbon electrode (GCE). The surface of GCE was functionalized with graphene by incubating it with graphene dispersed in 3-aminopropyltriethoxysilane (APTES), which acted both as
Mingming Ren et al.
Materials science & engineering. C, Materials for biological applications, 56, 348-355 (2015-08-08)
Embryonic stem (ES) cells offer the potential to generate all cell types in the body, which provide a promising approach to repair tissue damage or dysfunction. In the past decade, great efforts have been made to induce the differentiation of
Jesus Prieto-Lloret et al.
The Journal of physiology, 593(11), 2459-2477 (2015-04-03)
Adult animals that have been perinatally exposed to oxygen-rich atmospheres (hyperoxia), recalling those used for oxygen therapy in infants, exhibit a loss of hypoxic pulmonary vasoconstriction, whereas vasoconstriction elicited by depolarizing agents is maintained. Loss of pulmonary hypoxic vasoconstriction is
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