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Showing 1-30 of 589 results for "75633" within Papers
Ali Mehanna et al.
Experimental neurology, 261, 147-155 (2014-06-27)
The immune system plays important functional roles in regeneration after injury to the mammalian central and peripheral nervous systems. After damage to the peripheral nerve several types of immune cells, invade the nerve within hours after the injury. To gain
Sofia Arnaouteli et al.
The Journal of biological chemistry, 290(21), 13465-13478 (2015-04-01)
Membrane-anchored lipoproteins have a broad range of functions and play key roles in several cellular processes in Gram-positive bacteria. BA0330 and BA0331 are the only lipoproteins among the 11 known or putative polysaccharide deacetylases of Bacillus anthracis. We found that
Lucy Coughlin et al.
Investigative ophthalmology & visual science, 56(3), 1437-1446 (2015-02-07)
Decreased ATP correlates with intraocular pressure exposure in the optic nerves of mice with glaucoma. To understand what underlies this energy deficit, we examined mitochondria in the myelinated optic nerve axons of the DBA/2J mouse, a model of glaucoma secondary
Marimuthu Anandharaj et al.
Research in microbiology, 166(5), 428-439 (2015-04-04)
This study sought to evaluate the probiotic potential of lactic acid bacteria (LAB) isolated from traditionally fermented south Indian koozh and gherkin (cucumber). A total of 51 LAB strains were isolated, among which four were identified as Lactobacillus spp. and
Ming Pei et al.
Bone, 78, 1-10 (2015-05-06)
Repairing large bone defects presents a significant challenge, especially in those people who have a limited regenerative capacity such as in osteoporotic (OP) patients. The aim of this study was to compare adipose stem cells (ASCs) from both normal (NORM)
Amani Makkouk et al.
Cancer immunology research, 3(4), 389-398 (2015-01-30)
In situ immunization aims at generating antitumor immune responses through manipulating the tumor microenvironment. On the basis of recent advances in the understanding of antitumor immunity, we designed a three-step approach to in situ immunization to lymphoma: (i) inducing immunogenic
Hongyu Ying et al.
BMC cell biology, 16, 14-14 (2015-05-07)
Optineurin is a gene associated with normal tension glaucoma and amyotrophic lateral sclerosis. It has been reported previously that in cultured RGC5 cells, the turnover of endogenous optineurin involves mainly the ubiquitin-proteasome pathway (UPP). When optineurin is upregulated or mutated
Andrea Valigurová et al.
PloS one, 10(4), e0125063-e0125063 (2015-04-29)
This study focused on the attachment strategy, cell structure and the host-parasite interactions of the protococcidian Eleutheroschizon duboscqi, parasitising the polychaete Scoloplos armiger. The attached trophozoites and gamonts of E. duboscqi were detected at different development stages. The parasite develops
Giulia Salvatore et al.
Journal of lipid research, 56(6), 1110-1122 (2015-04-03)
Interleukin 17A (IL-17A) is a proinflammatory cytokine involved in the pathogenesis of chronic inflammatory diseases. In the field of immunometabolism, we have studied the impact of IL-17A on the lipid metabolism of human in vitro-generated monocyte-derived dendritic cells (DCs). Microarrays
Helrik da Costa Cordeiro et al.
Acta tropica, 148, 46-50 (2015-04-26)
A new species of nematode, Squamasnema amazonica n. gen. n. sp., is described based on specimens found parasitizing the small intestine of Proechimys roberti (Rodentia: Echimyidae) collected during a survey of the fauna of Tapirapé-Aquirí National Forest (Brazil, Eastern Brazilian
M Sousa et al.
Zygote (Cambridge, England), 23(1), 145-157 (2013-09-03)
Human oocyte dysmorphisms attain a large proportion of retrieved oocytes from assisted reproductive technology (ART) treatment cycles. Extracytoplasmic defects involve abnormal morphology of the zona pellucida (ZP), perivitelline space and first polar body. The aim of the present study was
R B Abdellatief et al.
Andrologia, 47(6), 674-679 (2014-09-18)
In a prospective experimental study, the effects of chronic tramadol administration on gonadotrophic and sex hormones, histopathological and morphometrical alterations in rat testicular tissue were investigated in a laboratory setting. Tramadol was given alone to adult male albino rats. Gonadotrophic
Virág T Takács et al.
Brain structure & function, 220(2), 919-940 (2014-01-11)
Three functionally different populations of perisomatic interneurons establish GABAergic synapses on hippocampal pyramidal cells: parvalbumin (PV)-containing basket cells, type 1 cannabinoid receptor (CB1)-positive basket cells both of which target somata, and PV-positive axo-axonic cells that innervate axon initial segments. Using
Giulia Quattrocolo et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(39), 13018-13032 (2014-09-26)
Cajal-Retzius cells orchestrate the development of cortical circuits by secreting the glycoprotein reelin. However, their computational functions are still unknown. In fact, the nature of their postsynaptic targets, major neurotransmitter released, as well as the class of postsynaptic receptors activated
Liguang Zhou et al.
Applied and environmental microbiology, 81(3), 831-839 (2014-11-16)
Methanosaeta spp. are widely distributed in natural environments, and their filamentous cells contribute significantly to sludge granulation and the good performance of anaerobic reactors. A previous study indicated that Methanosaeta harundinacea 6Ac displays a quorum sensing-regulated morphological transition from short
Katharina M Uhlig et al.
Journal of virology, 89(17), 9044-9060 (2015-06-19)
To induce and trigger innate and adaptive immune responses, antigen-presenting cells (APCs) take up and process antigens. Retroviral particles are capable of transferring not only genetic information but also foreign cargo proteins when they are genetically fused to viral structural
C Liu et al.
Current molecular medicine, 15(7), 663-673 (2015-09-01)
Glioblastoma multiforme (GBM) is the most lethal brain tumor and notorious for its resistance to ionizing radiation (IR). Recent evidence suggests that one possible mechanism that enables resistance to IR and protects cells against therapeutic stress is cellular autophagy. The
Yíngyún Caì et al.
PloS one, 9(11), e112060-e112060 (2014-11-20)
Middle East respiratory syndrome coronavirus (MERS-CoV) is a recently isolated betacoronavirus identified as the etiologic agent of a frequently fatal disease in Western Asia, Middle East respiratory syndrome. Attempts to identify the natural reservoirs of MERS-CoV have focused in part
Kuaifei Xia et al.
Plant, cell & environment, 38(12), 2662-2673 (2015-05-28)
Cuticular wax forms a hydrophobic layer covering aerial plant organs and acting as a protective barrier against biotic and abiotic stresses. Compared with well-known wax biosynthetic pathway, molecular regulation of wax biosynthesis is less known. Here, we show that rice
Chiara Focaccetti et al.
PloS one, 10(2), e0115686-e0115686 (2015-02-12)
Antimetabolites are a class of effective anticancer drugs interfering in essential biochemical processes. 5-Fluorouracil (5-FU) and its prodrug Capecitabine are widely used in the treatment of several solid tumors (gastro-intestinal, gynecological, head and neck, breast carcinomas). Therapy with fluoropyrimidines is
Irene Wacker et al.
Journal of microscopy, 259(2), 105-113 (2015-01-23)
For 3D reconstructions of whole immune cells from zebrafish, isolated from adult animals by FAC-sorting we employed array tomography on hundreds of serial sections deposited on silicon wafers. Image stacks were either recorded manually or automatically with the newly released
Gary Chinga-Carrasco et al.
Micron (Oxford, England : 1993), 44, 331-338 (2012-09-18)
The complementary capabilities of various characterisation methods for micro-structural assessment are demonstrated. The assessed structures were composed of unbleached microfibrillated cellulose (MFC) in combination with bleached and 2,2,6,6-tetramethylpiperidinyl-1-oxyl (TEMPO) pre-treated MFC materials. The biodegradable nano-composites were thus characterised in detail
Katherine M Murphy et al.
American journal of botany, 102(11), 1931-1937 (2015-11-04)
Although anthers of Zea mays, Oryza sativa, and Arabidopsis thaliana have been studied intensively using genetic and biochemical analyses in the past 20 years, few updates to anther anatomical and ultrastructural descriptions have been reported. For example, no transmission electron
Karthik Ramachandran et al.
Cell transplantation, 24(7), 1183-1194 (2014-05-20)
Human islets come in a variety of sizes and shapes, and the total volume of islets used for research or clinical transplants must be estimated in a manner that is simple and valid. Islet equivalent (IEQ) measurements are the standard
Dao-Fu Dai et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 30(8), 1370-1376 (2015-03-31)
Interstitial eosinophilic aggregates (IEA) in renal biopsies often suggest allergic tubulointerstitial nephritis, yet clear associations with drug reactions are often difficult to establish. IEA are also encountered in diabetic nephropathy (DN) and thought to be attributed to medication exposure. Native
Hui Wei et al.
Frontiers in plant science, 6, 315-315 (2015-06-02)
Identifying the cell wall-ionically bound glycoside hydrolases (GHs) in Arabidopsis stems is important for understanding the regulation of cell wall integrity. For cell wall proteomics studies, the preparation of clean cell wall fractions is a challenge since cell walls constitute
Jill M Fritz et al.
Molecular biology of the cell, 25(4), 431-440 (2013-12-18)
Endoplasmic reticulum-localized DnaJ 4 (ERdj4) is an immunoglobulin-binding protein (BiP) cochaperone and component of the endoplasmic reticulum-associated degradation (ERAD) pathway that functions to remove unfolded/misfolded substrates from the ER lumen under conditions of ER stress. To elucidate the function of
Olga E Mirgorodskaya et al.
Protoplasma, 252(5), 1313-1323 (2015-02-04)
Microsporogenesis and microgametogenesis of Rhododendron ledebourii (semi-deciduous), Rhododendron luteum (deciduous), and Rhododendron catawbiense (evergreen) were studied by light and electron microscopies in order to determine the stages of pollen development in relation to period of winter dormancy and bloom time
Seo Yeon Choi et al.
Cytometry. Part A : the journal of the International Society for Analytical Cytology, 85(9), 771-780 (2014-07-02)
In this study, we have demonstrated feasibility of a semi-quantitative approach for the estimation of cellular SiO2 nanoparticles (NPs), which is based on the flow cytometry measurements of their normalized side scattering intensity. In order to improve our understanding on
Fariba Javdani et al.
The Journal of comparative neurology, 523(13), 1967-1983 (2015-03-13)
γ-Aminobutyric acid (GABA)- and glycine-mediated hyperpolarizing inhibition is associated with a chloride influx that depends on the inwardly directed chloride electrochemical gradient. In neurons, the extrusion of chloride from the cytosol primarily depends on the expression of an isoform of
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