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Showing 1-30 of 100 results for "78-70-6" within Papers
Yan-Xia Pan et al.
Journal of cardiovascular pharmacology, 44 Suppl 1, S117-S120 (2005-04-20)
The heat shock protein 70 and glucose-regulated protein 78 have been shown to protect cells against deleterious stimuli. This study was performed to determine whether endothelin-1 pretreatment could increase cardiomyocyte tolerance to hypoxia and induce heat shock protein 70 and
R M Quock et al.
Brain research, 725(1), 23-29 (1996-06-24)
Among inbred mouse strains, DBA/2 mice are unique because of their poor responsiveness to nitrous oxide (N2O) antinociception. As a first step towards identifying candidate genes involved in determining antinociceptive responsiveness to N2O, male mice from the DBA/2 strain, the
Yeshwant Singh et al.
Asian Pacific journal of tropical medicine, 8(8), 630-635 (2015-09-01)
To determine the potential drug-drug interactions between anti-malarial candidate 97/78 and anti-tubercular drug rifabutin in-vivo in rats followed by in-vitro investigation of the underlying mechanisms of drug interaction. Single oral dose study was conducted in male and female rats at
Rodney J Moreland et al.
The Journal of biological chemistry, 280(8), 6780-6791 (2004-11-03)
Pompe's disease is caused by a deficiency of the lysosomal enzyme acid alpha-glucosidase (GAA). GAA is synthesized as a 110-kDa precursor containing N-linked carbohydrates modified with mannose 6-phosphate groups. Following trafficking to the lysosome, presumably via the mannose 6-phosphate receptor
Barbara Mroczko et al.
Journal of clinical laboratory analysis, 24(4), 256-261 (2010-07-14)
Previous studies have shown elevated serum levels of interleukin 6 (IL-6) and C-reactive protein (CRP) in patients with pancreatic cancer (PC). The aim of this study was to assess the diagnostic usefulness of pretreatment serum levels of IL-6 and CRP
Joan H Admirand et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 17(8), 954-961 (2004-05-11)
Using immunohistochemical methods, we evaluated zeta-associated protein (ZAP)-70 expression in 341 cases of non-Hodgkin and Hodgkin lymphoma. In B-cell NHL, ZAP-70 was positive in five of six (83%) precursor B-lymphoblastic lymphoma, 11 of 37 (30%) chronic lymphocytic leukemia/small lymphocytic lymphoma
Junzhen Zhong et al.
Food chemistry, 199, 387-392 (2016-01-19)
β-Lactoglobulin (β-LG) was conjugated with monomethoxy polyethylene glycol-succinimidyl carbonates (mPEG-SC, 20 kDa) to investigate the relationship between the antigenicity and conformational changes of β-LG. The effect of molar ratio of protein to mPEG-SC (1:3-1:6), pH (6-8) and time (4-24h) on
Xue Hou et al.
Food chemistry, 153, 121-129 (2014-02-05)
A modified QuEChERS (quick, easy, cheap, effective, rugged and safe) method using multi-walled carbon nanotubes (MWCNTs) as a dispersive solid phase extraction (d-SPE) absorbent was established for analysis of 78 pesticide residues in tea. A 6 mg MWCNT sample was
Bryan A Bassig et al.
Environmental and molecular mutagenesis, 54(6), 450-454 (2013-06-26)
To evaluate the immunotoxicity of trichloroethylene (TCE), we conducted a cross-sectional molecular epidemiology study in China of workers exposed to TCE. We measured serum levels of IL-6, IL-10, and TNF-α, which play a critical role in regulating various components of
Ian F Burgess et al.
BMJ (Clinical research ed.), 330(7505), 1423-1423 (2005-06-14)
To evaluate the efficacy and safety of 4% dimeticone lotion for treatment of head louse infestation. Randomised controlled equivalence trial. Community, with home visits. 214 young people aged 4 to 18 years and 39 adults with active head louse infestation.
R Lavery et al.
Archives of andrology, 53(2), 71-73 (2007-04-25)
This study developed quantitative real-time PCR assays for the DAZ and RBMY1 genes to determine the copy number of RNA extracted from testicular biopsies from a cohort of normospermic controls (n=6) and azoospermic males (n=17) including two males with Y-chromosome
Zhen-Chao Xu et al.
World journal of gastroenterology, 21(24), 7468-7477 (2015-07-04)
To explore the effect of grape seed proanthocyanidin (GSP) in liver ischemia/reperfusion (IR) injury and alleviation of endoplasmic reticulum stress. Male Sprague-Dawley rats (220-250 g) were divided into three groups, namely, sham, IR, and GSP groups (n = 8 each).
B Dautzenberg
Infection, 25(1), 63-66 (1997-01-01)
The MICs of rifabutin on Mycobacterium avium are compatible with its efficacy in clinical infections. Two North American trials established the prophylactic effect of rifabutin in disseminated M. avium disease in AIDS patients. Several prospective non-randomized trials show the clinical
Michael Caspers et al.
Thrombosis and haemostasis, 108(2), 247-257 (2012-05-26)
Deficiencies of natural anticoagulant proteins including antithrombin (AT), protein C (PC) and protein S (PS) are important causes of inherited thrombophilia. This study aimed to report on the practical experience gained in performing genetic analyses of a large cohort of
Steven Attia et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 3(9), 1018-1025 (2008-09-02)
Exisulind is an apoptotic agent with preclinical activity in non-small cell lung cancer (NSCLC). Vinorelbine is safe and effective in older patients with advanced NSCLC. We assessed these agents together as palliative treatment for older patients with advanced NSCLC. Chemotherapy-naive
Renée M Overmeer et al.
International journal of cancer, 129(9), 2218-2225 (2010-12-31)
Given the lower specificity for high-grade cervical lesions of high-risk human papillomavirus (hrHPV) testing compared to cytology, additional triage testing for hrHPV test-positive women is needed to detect high-grade cervical lesions. Here, we tested whether combined methylation analysis for cell
S Nyberg et al.
The American journal of psychiatry, 156(6), 869-875 (1999-06-09)
Multicenter trials with the novel antipsychotic risperidone have suggested a standard dose of 6 mg/day. However, a dose producing the highest response rate in fixed-dose studies is likely to exceed the minimal effective dose in most patients. The aim of
G Rijksen et al.
Biochimica et biophysica acta, 719(3), 431-437 (1982-12-17)
The isozyme distribution, kinetic properties and intracellular localization of hexokinase (ADP:D-hexose-6-phosphotransferase, EC were studied in erythrocytes, blood platelets, lymphocytes and granulocytes. Soluble and particulate fractions were separated by a rapid density centrifugation method after controlled digitonin-induced cell lysis. In
Chen-Zheng Huang et al.
International journal of clinical pharmacology and therapeutics, 50(7), 461-467 (2012-05-15)
Signal transducer and activator of transcription (STAT) 6 signaling pathway is required for mediating the biologic functions of interleukin (IL)-4 which is proved to play an important role in the pathogenesis of allergic diseases and the induction of specific immunoglobulin
Wulf Paschen et al.
Journal of neurochemistry, 88(4), 983-992 (2004-02-06)
Brain trauma was induced in mice using a closed head injury (CHI) model. At 1, 6 or 24 h after trauma, brains were dissected into the cortex, striatum and hippocampus. Changes in levels of processed X-box protein 1 (xbp1), glucose-regulated
Wayne L Furman et al.
Investigational new drugs, 30(4), 1660-1670 (2011-07-29)
Gefitinib potently inhibits neuroblastoma proliferation in vitro, and the gefitinib/irinotecan combination shows greater than additive activity against neuroblastoma xenografts. This Phase II pilot study estimated the rate of response to two courses of intravenous irinotecan plus oral gefitinib in children
Rachel E Farquhar et al.
Frontiers in physiology, 13, 905834-905834 (2022-07-15)
Targeting proteins to a specific membrane is crucial for proper epithelial cell function. KCa3.1, a calcium-activated, intermediate-conductance potassium channel, is targeted to the basolateral membrane (BLM) in epithelial cells. Surprisingly, the mechanism of KCa3.1 membrane targeting is poorly understood. We
S F Ali et al.
Molecular neurobiology, 11(1-3), 145-154 (1995-08-01)
Drugs of abuse, such as phencyclidine (PCP), methamphetamine (METH), and cocaine (COC) are known to affect several behaviors in rats, such as motor activity, stereotypy, and circling. In this study, we evaluated whether these drugs produce circling preferences in the
Vanisree Mulabagal et al.
Evidence-based complementary and alternative medicine : eCAM, 2011, 601249-601249 (2009-05-21)
Tea prepared from the aerial parts of Antigonon leptopus is used as a remedy for cold and pain relief in many countries. In this study, A. leptopus tea, prepared from the dried aerial parts, was evaluated for lipid peroxidation (LPO)
Jiaying Lin et al.
Neoplasia (New York, N.Y.), 19(1), 43-53 (2017-01-24)
We previously reported that overexpression of an O-type glycosyltransferase, GALNT6 (polypeptide N-acetylgalactosaminyltransferase 6) played critical roles in mammary carcinogenesis. To further investigate the biological function of GALNT6, we screened a substrate protein(s) of GALNT6 using a VVA (Vicia villosa agglutinin)
Young Suk Kim et al.
International journal of radiation oncology, biology, physics, 84(3), 661-667 (2012-03-15)
Recently, cells deficient in O(6)-methylguanine-DNA methyltransferase (MGMT) were found to show increased sensitivity to temozolomide (TMZ). We evaluated whether hypermethylation of MGMT was associated with survival in patients with glioblastoma multiforme (GBM). We retrospectively analyzed 93 patients with histologically confirmed
Seung-Hyun Lee et al.
Protein science : a publication of the Protein Society, 15(2), 304-313 (2005-12-31)
High hydrostatic pressure (HHP)-mediated solubilization and refolding of five inclusion bodies (IBs) produced from bacteria, three gram-negative binding proteins (GNBP1, GNBP2, and GNBP3) from Drosophila, and two phosphatases from human were investigated in combination of a redox-shuffling agent (2 mM
Julie M Vose et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 19(1), 123-128 (2012-09-04)
The purpose of this study was to evaluate the standard outpatient dose of 131-Iodine tositumomab (75 cGy) combined with high-dose carmustine, etoposide, cytarabine, and melphalan (BEAM) followed by autologous stem cell rescue for the treatment of chemotherapy-sensitive relapsed or refractory
J S Plested et al.
Infection and immunity, 67(10), 5417-5426 (1999-09-25)
We investigated the conservation and antibody accessibility of inner core epitopes of Neisseria meningitidis lipopolysaccharide (LPS) because of their potential as vaccine candidates. An immunoglobulin G3 murine monoclonal antibody (MAb), designated MAb B5, was obtained by immunizing mice with a
Anne Juuti et al.
Oncology, 68(2-3), 97-106 (2005-05-12)
Syndecan-1 is a transmembrane receptor that participates in cell-cell and cell-matrix interactions, cell proliferation and cell migration. Expression of syndecan-1 is downregulated in many cancers, but in pancreatic ductal adenocarcinoma it is upregulated. We studied the immunohistochemical expression of syndecan-1
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