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Showing 1-30 of 352 results for "79622" within Papers
Noemi GonzĆ”lez-AbuĆn et al.
Food & function, 5(9), 2357-2364 (2014-08-05)
We have previously reported that procyanidins, a class of flavonoids, improve glycemia and exert an incretin-like effect, which was linked to their proven inhibitory effect on the dipeptidyl-peptidase 4 (DPP4) activity. However, their actual effect on incretin levels has not
Rouhollah Karami-Osboo et al.
Journal of food science and technology, 52(4), 2440-2445 (2015-04-02)
A method based on dispersive liquid-liquid microextraction (DLLME) was developed for the quantitative extraction of Ochratoxin A (OTA) from raisin samples. The influence of various parameters on the recovery of OTA such as type and volume of DLLME extractant, centrifuging
Abhishek Mandal et al.
Biophysical journal, 109(9), 1873-1884 (2015-11-05)
The cellular process of intrinsic apoptosis relies on the peroxidation of mitochondrial lipids as a critical molecular signal. Lipid peroxidation is connected to increases in mitochondrial reactive oxygen species, but there is also a required role for mitochondrial cytochrome c
Jun-Wei Zhang et al.
Chemical communications (Cambridge, England), 49(70), 7750-7752 (2013-07-26)
Chiral phosphoric acid and Hoveyda-Grubbs II were found to catalyze an olefin cross-metathesis-intramolecular oxo-Michael cascade reaction of the ortho-allylphenols and enones to provide a variety of benzofuran and benzoxazine derivatives in moderate to good yields and enantioselectivity.
Emma-Dune Leriche et al.
Molecules (Basel, Switzerland), 19(12), 20731-20750 (2014-12-17)
Highly branched polyamidoamine (PAMAM) dendrimers presenting biological activities have been envisaged as non-viral gene delivery vectors. They are known to associate with nucleic acid (DNA) in non-covalent complexes via electrostatic interactions. Although their transfection efficiency has been proved, PAMAMs present
Jin Zhang et al.
Journal of pharmaceutical and biomedical analysis, 98, 247-252 (2014-06-20)
Peak tailing of phosphate prodrugs in acidic mobile phases was thoroughly investigated. The results indicated that both metal-phosphate interactions and silanophilic interactions contributed to the observed peak tailing. Column pretreatment with phosphate buffers was demonstrated to be an effective and
Catalin Koro et al.
European journal of immunology, 44(11), 3403-3412 (2014-08-19)
Post-translational modifications of proteins significantly affect their structure and function. The carbamylation of positively charged lysine residues to form neutral homoitrulline occurs primarily under inflammatory conditions through myeloperoxidase-dependent cyanate (CNO-) formation. We analyzed the pattern of human IgG1 carbamylation under
Li Yan Chan et al.
The Journal of organic chemistry, 78(17), 8826-8832 (2013-08-07)
A simple and efficient method is developed for Pd-catalyzed ortho-acetoxylation using organophosphates, namely, benzylic phosphonic and aryl phosphoric monoacids, as the directing group.
Tarek A Ahmed et al.
AAPS PharmSciTech, 15(3), 772-780 (2014-03-22)
The objective of this study was to investigate the sustained release of a hydrophilic drug, montelukast (MK), from two biodegradable polymeric drug delivery systems, in situ implant (ISI) and in situ microparticles (ISM). N-Methyl pyrrolidone (NMP), dimethyl sulfoxide (DMSO), triacetin
Xabier Osteikoetxea et al.
PloS one, 10(3), e0121184-e0121184 (2015-03-24)
In recent years the study of extracellular vesicles has gathered much scientific and clinical interest. As the field is expanding, it is becoming clear that better methods for characterization and quantification of extracellular vesicles as well as better standards to
T Noelle Lombana et al.
Scientific reports, 5, 17488-17488 (2015-12-04)
Rapid identification of residues that influence antibody expression and thermostability is often needed to move promising therapeutics into the clinic. To establish a method that can assess small expression differences, we developed a Bacterial Antibody Display (BAD) system that overcomes
Joanna Znaleziona et al.
Journal of pharmaceutical and biomedical analysis, 105, 10-16 (2014-12-22)
The chiral recognition of the centrally acting analgesic agent tapentadol and its isomers with various cyclodextrins (CDs) was studied by capillary electrophoresis, focusing on the migration order of four stereoisomers. In the case of non-charged hydroxypropylated CDs (2-hydroxypropyl-Ī²-CD, 2-hydroxypropyl-Ī³-CD) the
Magali Tanghe et al.
Molecular biotechnology, 57(11-12), 1010-1017 (2015-08-20)
The auxiliary activity family 9 (AA9, formerly GH61) harbors a recently discovered group of oxidative enzymes that boost cellulose degradation. Indeed, these lytic polysaccharide monooxygenases (LPMOs) are able to disrupt the crystalline structure of cellulose, thereby facilitating the work of
Mahsa Moeinian et al.
World journal of gastroenterology, 20(31), 10876-10885 (2014-08-26)
To investigate the beneficial effect of the combination of butyrate, Lactobacillus casei, and L-carnitine in a rat colitis model. Rats were divided into seven groups. Four groups received oral butyrate, L-carnitine, Lactobacillus casei and the combination of three agents for
A A Gryshchenko et al.
Bioorganic & medicinal chemistry, 23(9), 2287-2293 (2015-03-31)
Fibroblast grow factor receptor 1 (FGFR1) is an important anti-cancer target that plays crucial role in oncogenesis and oncogenic angiogenesis. The structure-activity relationship (SAR) of N-phenylthieno[2,3-d]pyrimidin-4-amines was investigated. Binding of active compounds with FGFR1 kinase was analyzed by molecular modeling
Surya Prakash Rao Pydimarry et al.
Journal of chromatographic science, 52(1), 42-51 (2012-12-22)
A simple, sensitive, precise and accurate stability-indicating ultra-performance liquid chromatography (UPLC) method was developed for the quantitative determination of the purity of the active pharmaceutical ingredient of milnacipran hydrochloride (MCP) and its pharmaceutical dosage form in the presence of its
Li-Hong Ye et al.
Analytical and bioanalytical chemistry, 407(6), 1763-1773 (2014-12-21)
A novel effervescent-salt-assisted dispersive micro-solid-phase extraction using mesoporous hybrid materials was developed for the extraction of minute traces of constituents in complicated plant preparations. In this study, a special tablet containing carbon dioxide sources (sodium dihydrogenphosphate and sodium carbonate) and
Michela Mori et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 88(3), 635-642 (2014-10-12)
The wound healing stands as very complex and dynamic process, aiming the re-establishment of the damaged tissue's integrity and functionality. Thus, there is an emerging need for developing biopolymer-based composites capable of actively promoting cellular proliferation and reconstituting the extracellular
Wei Zhou et al.
PloS one, 9(10), e109619-e109619 (2014-10-03)
The Flos Lonicerae-Fructus Forsythiae herb couple is the basic components of Chinese herbal preparations (Shuang-Huang-Lian tablet, Yin-Qiao-Jie-Du tablet and Fufang Qin-Lan oral liquid), and its pharmacological effects were significantly higher than that in Flos Lonicerae or Fructus Forsythiae, but the
Dilusha M Fernando et al.
BMC complementary and alternative medicine, 15, 398-398 (2015-11-08)
Macrofungi have an established history of use in traditional oriental medicine. Anthracophyllum lateritium is a terrestrial macrofungus found in the dry zone forest reserves in Sri Lanka. Yet there are no scientific reports on bioactive properties of this species. Hence
Ali M Yehia et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 153, 231-240 (2015-09-01)
Spectral resolution of cefquinome sulfate (CFQ) in the presence of its degradation products was studied. Three selective, accurate and rapid spectrophotometric methods were performed for the determination of CFQ in the presence of either its hydrolytic, oxidative or photo-degradation products.
Amir Ahmad Ajami et al.
The journal of contemporary dental practice, 14(1), 26-33 (2013-04-13)
This study evaluated the effect of three different contamination removal methods on bond strength of one-step self-etching adhesive to dentin contaminated with an aluminum chloride hemostatic agent. One hundred noncarious adult molars were used in this study; 2-mm-thick dentin disks
Kazuhiro Higuchi et al.
Organic letters, 17(1), 154-157 (2014-12-20)
The asymmetric total synthesis of (-)-leuconoxine has been achieved. The desymmetrization of a prochiral diester using a chiral phosphoric acid catalyst produced a highly enantioenriched lactam with excellent yield. The ring construction featuring an intramolecular N-acyliminium cyclization and the one-step
Nikolaos Psychogios et al.
PloS one, 6(2), e16957-e16957 (2011-03-02)
Continuing improvements in analytical technology along with an increased interest in performing comprehensive, quantitative metabolic profiling, is leading to increased interest pressures within the metabolomics community to develop centralized metabolite reference resources for certain clinically important biofluids, such as cerebrospinal
Anand Babu et al.
Pharmaceutical biology, 53(6), 838-848 (2014-11-29)
Curcumin exhibits a wide spectrum of biological activities which include neuroprotective, antinociceptive, anti-inflammatory, and antioxidant activity. The present study evaluates the effect of curcumin in vincristine-induced neuropathy in a mice model. Vincristine sulfate (0.1 mg/kg, i.p. for 10 consecutive days)
Jeevan Thavanathan et al.
International journal of nanomedicine, 10, 2711-2722 (2015-04-22)
We have developed a colorimetric biosensor using a dual platform of gold nanoparticles and graphene oxide sheets for the detection of Salmonella enterica. The presence of the invA gene in S. enterica causes a change in color of the biosensor
Toni E Newsome et al.
Journal of chromatography. A, 1364, 261-270 (2014-09-15)
Nanofibrous silica-based stationary phases for electrospun ultra-thin layer chromatography (E-UTLC) are described. Nanofibers were produced by electrospinning a solution of silica nanoparticles dispersed in polyvinylpyrrolidone solutions to create composite silica/polymer nanofibers. Stationary phases were created from as-spun nanofibers, or the
Li Chu et al.
DNA and cell biology, 34(3), 178-188 (2015-01-22)
The traditional Chinese medicinal formula BDL301 has been used to inhibit inflammation for hundreds of years. The development of colorectal cancer and chronic inflammation are closely related. In this study, we investigated whether BDL301 could inhibit tumor growth. We found
Roshan Uthappa et al.
The journal of contemporary dental practice, 13(6), 756-759 (2013-02-14)
The purpose of the study was to compare two different commercial bleaching agents, Opalescence with Colgate Platinum, and 30% phosphoric acid used as aggressive agent on the morphology of human enamel. Ten freshly extracted, noncarious, human maxillary central incisors extracted
Mustafa Demirci et al.
Clinical oral investigations, 19(9), 2187-2199 (2015-03-25)
To evaluate the medium-term clinical performance of direct composite build-ups for diastema closures and teeth recontouring using a nano and a nanohybrid composite in combination with three- or two-step etch-and-rinse adhesives following treatment with fixed orthodontic appliances. A total of
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