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The Effective Use of Protein Kinase Inhibitors
92 86 100 87 75 106 81 25 109 95 101 6 32 18
GSK-3β 107 92 90 13 38 105 83 101 66 61 85 53 30 89 58 99 5 50 46
ROCK-II 0 13 7
The Effective Use of Protein Kinase Inhibitors
92 86 100 87 75 106 81 25 109 95 101 6 32 18
GSK-3β 107 92 90 13 38 105 83 101 66 61 85 53 30 89 58 99 5 50 46
ROCK-II 0 13 7
Polyvinyl alcohol: Revival of a long lost polymer
25%
PVA 18–88 ✓ ✓ 18%
PVA 26–88 ✓ ✓ 15%
PVA 40–88 ✓ ✓ 13%
PVA 28–99 ✓ ✓ 15%
* Maximum solubility was defined as the concentration at which the mixture exceeded
Poster - PVA as binder in continuous twin-screw granulation
Mannitol (Pearlitol
50C, Roquette, Lestrem) as hydrophilic filler. Different
grades of PVA (4-88, 18-88, 40-88, MilliporeSigma,
Germany) were used as binder, 5% w/w was added
to the filler. Additionally
Use of Polyvinyl Alcohol as an effective Binder in Continuous Twin-Screw Granulation
100 200 300 400 500
PVA 4-88 PVA 18-88 PVA 40-88
2.5
0
0.5
1.0
1.5
2.0
0.085 0.090 0.095 0.100 0.110 0.115 0.120 0.125
PVA 18-88PVA 4-88 PVA 40-88
Product Information Sheet - CS0710
Solution
Lysis Buffer Reaction Mixture
Test X µl --- --- 88-X µl 12 µl
Blank --- --- --- 88 µl 12 µl
Modulator Reaction X µl --- Y µl 88-X-Y µl 12 µl
Data Sheet - E8154
(2000).
16. O’Reilly, M.S. et al., Cell, 88, 277-285 (1997).
17. Dixelius, J. et al., Cancer Res., 62, 1944-1947
(2002).
18. Miosge, M. et al., FASEB J., 13, 1743-1750 (1999).
19. Dhanabal, M. et al
Data Sheet - E8279
).
16. O′Reilly, M.S., et al., Cell, 88, 277-285 (1997).
17. Dixelius, J., et al., Cancer Res., 62, 1944-1947
(2002).
18. Miosge, M., et al., FASEB J., 13, 1743-1750
(1999).
19. Dhanabal M, et
Data Sheet - E1783
al., Brain Res., 1228, 6-13
(2008).
8. Chen, G. et al., Proteomics, 3, 496-504 (2003).
9. Balabanov, S. et al., Blood, 109, 1701-1711 (2007).
VS,DS,KAA,PHC,MAM 06/19-1
2019
Pellicon®3 Cassettes with Ultracel®Membrane Performance Guide
sizes 88 cm2 and 0.11 m2.
Cassettes
Torque
(in-lb)
Air
Diffusion
(cc/min)
at 30 psi
Air Diffusion
(cc/min)
at 100 psi
P3C010C00
(10 kDa, 88 cm2)
150 1 7
190 1 6
MILLIPLEX®MAP Human Myokine Panel is an optimized quantitative immunoassay that simultaneously measures 15 novel muscle-secreted factors
20480 3460 739890 30 20 40110 3110 2370 17170 37 9 570 790
%
detectable
88 88 100 63 100 50 13 38 100 38 88 75 88 63 50
Table 6.
Comparison of biomarkers expressed
Verfication summary-03-0202-00
.0 8% 88%
3 1:32 5.75 0.9 16% 184.09 29.3 16% 102%
HMN713788
3 MRD (1:4) 21.56 3.2 15% 86.25 12.6 15% -
3 1:8 11.27 0.4 4% 90.12 3.3 4% 104%
3 1:16 5.95 1.1
Data Sheet - G5419
(1996).
9. Karlsen, A.E., et al., Proc. Natl. Acad. Sci., 88,
8337 (1991).
10. Michelsen, B.K., et al., Proc. Natl. Acad. Sci., 88,
8754 (1991).
11. Kaufman, D.L., et al., J. Neurochem., 56
Protocol: Human Ghrelin (Active)
Recovery rate
1
0 (Basal) 325 -- 239 --
100 416 91% 338 99%
1,000 1,203
App Note: Analysis of Drugs of Abuse in Urine After Cleanup with New Supel™ Swift HLB Solid Phase Extraction 96-well Plates
Buprenorphine
44%
5.8%
13 Methadone
90%
2.7%
Overall*
88%
10.8
*Omits Buprenorphine
5
Figure 7. Matrix effects (ion suppression and ion enhancement) Across the 13 analytes. Purple dash
Data Sheet - F0550
1988).
8. Rothwell, V. M., and Rohrschneider, L. R.,
Oncogene Res., 1, 311-324 (1987).
9. Chabot, B., et al., Nature, 335, 88-89 (1988).
10. Geissler, E. N., et al., Cell, 55, 185-192 (1988).
11
Biological Evaluation of the MILLIPLEX®MAPMouse High Sensitivity T Cell Panel
GM-CSF 13 IL-10 100
IFNγ 94 100 IL-12 (p70) 63
IL-1α 100 IL-13 100
IL-1β 56 LIX 100
IL-2 93 62 IL-17A 100
IL-4 100 79 KC 100
IL-5
PTFE Membrane Filters - For filtering acids, bases, or solvents, as well as gases
70 10 13 14
EASTERN EUROPE,
C.I.S., AFRICA, MIDDLE
EAST AND GULF
Life Sciences Division:
Tel. +33 3 88 38 9536
Fax +33 3 88 38 9539
BioPharmaceutical Division:
Tel. +43 1 877-8926
Fax +43 1 877-1654
RonaCare Allantoin
Taipei
Taiwan
Phone: +88 6-2-27 42 27 88 ext. 640
Fax: +88 6-2-27 42 32 14
Internet: www.merck.com.tw
E-mail: [email protected]
Japan
Merck Ltd.
ARCO Tower, 5 F
8-1, Shimomeguro 1-chome
Meguro ku
Tokyo
Quality Control Range Sheet- FCY-109 and FCY-209
FAS Control 1 95 – 198 pg/mL IL-6 Control 1 428 – 889 pg/mL
Control 2 788 – 1638 pg/mL Control 2 3711 – 7707 pg/mL
Spare parts for Mobius®Bioreactors (50 L, 200 L, 1000 L & 2000 L)
x Critical
#88 SPKHPI175BRX FLOW CONVERTER LFC-1C-CS x x x x Critical
89 SPKHPI176BRX FLOW SENSOR EXT CABLE LFE-B.1-10S x x Critical
90 SPKHPI177BRX FLOW SENSOR EXT CABLE LFE-B.1-30 x x Critical
Data Sheet - T1815
, et al., Immunology, 88, 284 (1996).
5. de Rochemonteix, B.G., et al., Am. J. Respir. Cell
Mol. Biol., 14, 279 (1996).
6. Lewis, M., et al., Proc. Natl. Acad. Sci. USA, 88,
2830
Product Information Sheet - MD0100
Reaction
mix
Test X µl --- 88-X µl 12 µl
Blank --- --- 88 µl 12 µl
Positive
Control --- 2 µl 86 µl 12 µl
X is the volume of cell lysate
SMC®Plate Washer Evaluation Kit
61 11 18
H 97 76 89 77 80 83 85 71 87 88 78 81 83 7 9
Column Mean 78 65 72 63 69 67 65 63 64 73 61 81
SD 10 9 11
Pellicon® 3 Cassette with Ultracel® Membrane
NaOH at 50 °C up to 50 hours
Operating pH Range 2–13
Component Material Toxicity Component materials were tested and meet the criteria of the USP 88> Biological Reactivity Tests for Class VI Plastics
Data Sheet - G1166
(1996).
9. Karlsen, A.E., et al., Proc. Natl. Acad. Sci., 88,
8337 (1991).
10. Michelsen, B.K., et al., Proc. Natl. Acad. Sci., 88,
8754 (1991).
11. Kaufman, D.L. et al., J. Neurochem., 56
Pellicon® Single-Pass TFF Accessories Installation and User Guide
Installation and User Guide 13
Installation
Components
Key Description
1 Holder end plate
2 Gasket
3 Pellicon® Single-Pass TFF Mini diverter plate
4 Pellicon® 3 88 cm2 or 0.11 m2 Cassette
5 Tie
LABORATORY NOTEBOOK ISSUANCE PAGE
82
11
8.
71
12
1.
76
12
7.
60
12
6.
90
13
1.
29
20
4.
38
20
7.
2
20
8.
98
(2
09
)
(2
10
)
(2
22
)
(2
84
)
(2
89
)
LABORATORY NOTEBOOK ISSUANCE PAGE
82
11
8.
71
12
1.
76
12
7.
60
12
6.
90
13
1.
29
20
4.
38
20
7.
2
20
8.
98
(2
09
)
(2
10
)
(2
22
)
(2
84
)
(2
89
)
LABORATORY NOTEBOOK ISSUANCE PAGE
82
11
8.
71
12
1.
76
12
7.
60
12
6.
90
13
1.
29
20
4.
38
20
7.
2
20
8.
98
(2
09
)
(2
10
)
(2
22
)
(2
84
)
(2
89
)
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