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Showing 1-30 of 106 results for "88190" within Papers
Yasuro Atoji
Experimental eye research, 136, 72-77 (2015-05-20)
Glutamate is an excitatory neurotransmitter in the vertebrate retina. A previous study found vesicular glutamate transporter 2 (vGluT2) mRNA in the pigeon retina, suggesting that bipolar and ganglion cells are glutamatergic. The present study examined the localization of ionotropic glutamate
Yue Hu et al.
Journal of experimental botany, 66(15), 4733-4747 (2015-05-23)
The barley stripe mosaic virus (BSMV) triple gene block 1 (TGB1) protein is required for virus cell-to-cell movement. However, little information is available about how these activities are regulated by post-translational modifications. In this study, we showed that the BSMV
Jana Travnickova et al.
Nature communications, 6, 6227-6227 (2015-02-18)
In vertebrates, haematopoietic stem/progenitor cells (HSPCs) first emerge in the aorta-gonad-mesonephros (AGM) before colonizing transitory and subsequently definitive haematopoietic organs allowing haematopoiesis throughout adult life. Here we identify an unexpected primitive macrophage population accumulated in the dorsal mesenteric mesoderm surrounding
Helene Schulz et al.
Experimental and molecular pathology, 99(1), 33-38 (2015-05-07)
The epidermal growth factor (EGF)-like ligands and their cognate ERBB1-4 receptors represent important signaling pathways that regulate tissue and cell proliferation, differentiation and regeneration in a wide variety of tissues, including the urogenital tract. Betacellulin (BTC) can activate all four
Dongjuan Yuan et al.
Biochimica et biophysica acta, 1841(9), 1272-1284 (2014-05-08)
Eicosanoids play an important role in inducing complex and crucial physiological processes in animals. Eicosanoid biosynthesis in animals is widely reported; however, eicosanoid production in invertebrate tissue is remarkably different to vertebrates and in certain respects remains elusive. We, for
Karuppiah Muthumani et al.
Science translational medicine, 7(301), 301ra132-301ra132 (2015-08-21)
First identified in 2012, Middle East respiratory syndrome (MERS) is caused by an emerging human coronavirus, which is distinct from the severe acute respiratory syndrome coronavirus (SARS-CoV), and represents a novel member of the lineage C betacoronoviruses. Since its identification
Timothy P Holsgrove et al.
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 229(11), 769-777 (2015-10-28)
Thorough pre-testing is critical in assessing the likely in vivo performance of spinal devices prior to clinical use. However, there is a lack of data available concerning the dynamic testing of lumbar (porcine model) total disc replacements in all six
Wing Yan Yu et al.
Stem cells and development, 24(5), 624-639 (2014-10-18)
A growing body of evidence has revealed that stem-like cells in the posterior limbus of the eye between the corneal endothelium (CE) and trabecular meshwork (TM) may be able to rejuvenate these tissues in disease. However, these cells have not
Duc Fehr et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(46), E6265-E6273 (2015-11-19)
Noninvasive, radiological image-based detection and stratification of Gleason patterns can impact clinical outcomes, treatment selection, and the determination of disease status at diagnosis without subjecting patients to surgical biopsies. We present machine learning-based automatic classification of prostate cancer aggressiveness by
Ashima Saxena et al.
Chemico-biological interactions, 238, 161-169 (2015-07-07)
Serum-derived human butyrylcholinesterase (Hu BChE) is a stoichiometric bioscavenger that is being developed as a potential prophylactic nerve agent countermeasure. Previously, we reported the prophylactic efficacy of Hu BChE in Göttingen minipigs against a whole-body exposure to 4.1mg/m(3) of sarin
Andreza M F Aranha et al.
Dental materials : official publication of the Academy of Dental Materials, 22(9), 864-869 (2006-01-04)
The aim of this in vitro study was to evaluate the cytotoxicity of resin-modified glass-ionomer lining cements submitted to different curing regimes and applied to an immortalized odontoblast-cell line (MDPC-23). Forty round-shaped specimens of each experimental material (Fuji Lining LC
Izabella Baranowska Körberg et al.
Human molecular genetics, 24(18), 5069-5078 (2015-06-25)
Bladder exstrophy, a severe congenital urological malformation when a child is born with an open urinary bladder, is the most common form of bladder exstrophy-epispadias complex (BEEC) with an incidence of 1:30,000 children of Caucasian descent. Recent studies suggest that
M Ohlsson et al.
Neurology, 71(23), 1896-1901 (2008-12-03)
Mutations in the beta-tropomyosin gene (TPM2) are a rare cause of congenital myopathies with features of nemaline myopathy and cap disease and may also cause distal arthrogryposis syndromes without major muscle pathology. We describe the muscle biopsy findings in three
Roberta Russo et al.
The FEBS journal, 281(17), 3828-3843 (2014-07-22)
Growing evidence suggests that the transcription factors belonging to the Jun family are involved in many important cellular events, such as the control of bone development in mammalians. We have characterized, for the first time, a member of the Jun
Verónica Pérez-De La Cruz et al.
Brain research bulletin, 68(5), 379-383 (2005-12-27)
3-Nitropropionic acid is a neurotoxin that irreversibly inhibits succinate dehydrogenase, a relevant enzyme constituting the complex II of the respiratory chain during mitochondrial electron transport. 3-Nitropropionic acid is known to produce oxidative/nitrosative stress and evokes an experimental model of Huntington's
Paweł Laniewski et al.
Clinical and vaccine immunology : CVI, 21(9), 1267-1276 (2014-07-06)
Salmonella enterica serovar Gallinarum is the etiological agent of fowl typhoid, which constitutes a considerable economic problem for poultry growers in developing countries. The vaccination of chickens seems to be the most effective strategy to control the disease in those
Y C Chang et al.
Journal of endodontics, 27(2), 82-84 (2001-08-09)
Recently halothane has been reported to be the most suitable alternative to chloroform in dissolving gutta-percha. Periapical tissue toxicity of halothane is not completely known. In this study gutta-percha dissolved by halothane was evaluated with the almar blue dye assay
A Santa Maria et al.
Ecotoxicology and environmental safety, 39(3), 164-167 (1998-05-08)
A natural stimulant, Paullinia cupana, commonly called guarana, was tested for its ability to induce in vitro toxicity in Chinese hamster ovary (CHO) cells and bacterial cells (Photobacterium phosphoreum). The cytotoxic effects of aqueous guarana extracts were evaluated by three
Miguel Angel Martin-Piedra et al.
Cytotherapy, 15(4), 507-518 (2013-01-29)
One of the most important issues in tissue engineering (TE) is the search for a suitable stem cell reservoir with optimal cell viability levels for the development of new tissues relevant for therapeutic needs. The aim of this study was
Andrea Springer et al.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 46(3), 482-490 (2015-09-10)
Although research on lemurid primates in Madagascar has been ongoing for several decades, reports on different drug regimes to immobilize wild lemurs are limited. This study compares the efficacy, reliability, and side effects of ketamine-xylazine, ketamine-xylazine-atropine, and tiletamine-zolazepam immobilization in
Renata Rodrigues-Ribeiro et al.
Cell biochemistry and biophysics, 71(2), 1225-1233 (2014-11-12)
P2 receptors activated by ATP are expressed in the skeletal system. However, the role of P2 receptors in osteoblast differentiation remains unclear. Participation of P2 receptors in differentiation was investigated in the preosteoblast MC3T3-M1 cell line. Preosteoblasts were stimulated for
A S Amin
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 51(3), 267-272 (2001-05-10)
A simple, accurate and sensitive method for the determination of micro amounts of vitamin E (V(E)) in pure form and in multi-vitamin capsules is described. The method is based on the reduction of tetrazolium blue in slightly alkaline medium by
Stacia A Sower et al.
Endocrinology, 156(8), 3026-3037 (2015-06-13)
The gnathostome (jawed vertebrates) classical pituitary glycoprotein hormones, FSH, LH, and TSH, consist of a common α-subunit (GpA1) and unique β-subunits (Gpβ1, -2, and -3), whereas a recently identified pituitary glycoprotein hormone, thyrostimulin, consists of GpA2 and GpB5. This paper
M Shokrzadeh et al.
Drug research, 65(6), 281-286 (2014-03-29)
This study was undertaken to evaluate the protective effects of melatonin against cyclophosphamide (CP)-induced oxidative lung toxicity in mice. Mice were pre-treated with various doses of melatonin for 7 consecutive days and were then injected with CP (200 mg/kg b.
Y Mizutani et al.
The Journal of urology, 160(2), 561-570 (1998-07-29)
The resistance of bladder cancer to anticancer chemotherapeutic drugs is a major problem. Several immunotherapeutic approaches have been developed to treat drug-resistant tumor cells. The Fas antigen (Fas)-Fas ligand pathway is involved in cytotoxic T lymphocyte and natural killer cell-mediated
Jean-Michel Lemée et al.
Journal of neuro-oncology, 122(1), 53-61 (2015-01-07)
Glioblastoma (GB) is the most frequent and aggressive type of primary brain tumor. Recurrences are mostly located at the margin of the resection cavity in the peritumoral brain zone (PBZ). Although it is widely believed that infiltrative tumor cells in
Shaotong Zhu et al.
The Journal of biological chemistry, 290(34), 20761-20773 (2015-07-03)
Complex I (NADH:ubiquinone oxidoreductase) is a multisubunit, membrane-bound enzyme of the respiratory chain. The energy from NADH oxidation in the peripheral region of the enzyme is used to drive proton translocation across the membrane. One of the integral membrane subunits
Jeffrey D Kearns et al.
Molecular cancer therapeutics, 14(7), 1625-1636 (2015-04-26)
Although EGFR is a validated therapeutic target across multiple cancer indications, the often modest clinical responses to current anti-EGFR agents suggest the need for improved therapeutics. Here, we demonstrate that signal amplification driven by high-affinity EGFR ligands limits the capacity
Tetrazolium-based colorimetric assay for the detection of HIV replication inhibitors: revisited 20 years later.
Pannecouque C, Daelemans D, and De Clercq E
Nature Protocols, 3(3), 427-434 (2008)
Valerio Magnaghi et al.
The European journal of neuroscience, 19(10), 2641-2649 (2004-05-19)
The location and the role of gamma-aminobutyric acid type B (GABA(B)) receptors in the central nervous system have recently received considerable attention, whilst relatively little is known regarding the peripheral nervous system. In this regard, here we demonstrate for the
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