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Showing 1-30 of 479 results for "90340" within Papers
P Kannampalli et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 26(12), 1694-1704 (2014-10-10)
Increasing evidence indicates a positive effect of probiotics on the nervous system. The objective of this study was to determine if probiotic Lactobacillus rhamnosus GG (LGG) and/or prebiotics polydextrose/galactooligosaccharide (PDX/GOS) can alter the colonic sensitivity in a neonatal rat model
Keith E Levine et al.
Talanta, 140, 115-121 (2015-06-07)
Organotin compounds (OTCs) are heavily employed by industry for a wide variety of applications, including the production of plastics and as biocides. Reports of environmental prevalence, differential toxicity between OTCs, and poorly characterized human exposure have fueled the demand for
Davy Baudelet et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 986-987, 35-43 (2015-02-24)
The P2X receptors are seven-transmembrane domain G protein-coupled receptors and the 7 subtypes of P2X receptors identified in humans, and named P2X1 to P2X7, are channel receptors whose endogenous ligand is ATP. New antagonists of the P2X7 receptor were developed
Cynthia M Antonio-Cisneros et al.
International journal of molecular sciences, 16(1), 1590-1612 (2015-01-15)
Applications of carbon-TiO2 materials have attracted attention in nanotechnology due to their synergic effects. We report the immobilization of TiO2 on carbon prepared from residues of the plant Manihot, commercial TiO2 and glycerol. The objective was to obtain a moderate
Wei Li et al.
Journal of pharmaceutical and biomedical analysis, 114, 341-347 (2015-06-24)
A novel simple, fast and efficient supercritical fluid chromatography (SFC) method was developed and compared with RPLC method for the separation and determination of impurities in rifampicin. The separation was performed using a packed diol column and a mobile phase
Zhoumeng Lin et al.
Toxicological sciences : an official journal of the Society of Toxicology, 141(1), 90-102 (2014-06-11)
Atrazine (ATR) is one of the most frequently detected pesticides in the U.S. water supply. This study aimed to investigate neurobehavioral and neurochemical effects of ATR in C57BL/6 mouse offspring and dams exposed to a relatively low (3 mg/l, estimated
Wen Hu et al.
Colloids and surfaces. B, Biointerfaces, 123, 254-263 (2014-10-04)
Nanocarriers with low toxicity, high stability, long circulation in blood and triggered drug release at target sites are extremely needed for cancer therapy. In this study, different molar ratios of poly (ethylene glycol) (PEG) were conjugated to poly (amidoamine) dendrimer
Rahul Narayanan et al.
Angewandte Chemie (International ed. in English), 53(23), 5936-5940 (2014-03-20)
Ambient ionization is achieved by spraying from a carbon nanotube (CNT)-impregnated paper surface under the influence of small voltages (≥3 V). Organic molecules give simple high-quality mass spectra without fragmentation in the positive or negative ion modes. Conventional field ionization is
Stacy M Copp et al.
ACS nano, 9(3), 2303-2310 (2015-01-30)
The remarkable precision that DNA scaffolds provide for arraying nanoscale optical elements enables optical phenomena that arise from interactions of metal nanoparticles, dye molecules, and quantum dots placed at nanoscale separations. However, control of ensemble optical properties has been limited
Manos Gkikas et al.
Biomacromolecules, 16(11), 3686-3693 (2015-10-16)
Novel poly(L-lysine)-block-poly(L-proline) (PLL-b-PLP)-based materials with all PLP helical conformers, i.e., PLP II and the rare PLP I are here reported. Electrostatic supramolecular complexation of the adjacent cationic PLL with anionic molecules bearing DNA analogue H-bonding functionalities, such as deoxyguanosine monophosphate
Anita Aranyi et al.
Journal of chromatography. A, 1387, 123-133 (2015-02-18)
The direct separation of the enantiomers of 1-(α-aminoarylmethyl)-2-naphthol, 1-(α-aminoalkyl)-2-naphthol, 2-(α-aminoarylmethyl)-1-naphthol analogues and 2-(1-amino-2-methylpropyl)-1-naphthol) was investigated in supercritical fluid chromatography. Five commercially available chiral stationary phases based on immobilized polysaccharide chiral selectors (Chiralpak IA, IB, IC, ID and IE) were evaluated.
Qin-Hua Gu et al.
Nature communications, 6, 6789-6789 (2015-04-11)
Long-term potentiation (LTP) is a form of synaptic plasticity that results in enhanced synaptic strength. It is associated with the formation and enlargement of dendritic spines-tiny protrusions accommodating excitatory synapses. Both LTP and spine remodelling are crucial for brain development
Nusheng Chen et al.
Carbohydrate polymers, 128, 122-129 (2015-05-26)
Biocomposites with tunable properties were successfully prepared through ionic assembly between anionic carboxymethyl cellulose (CMC) and cationic copolymers (quaternized poly(l-lactide)-block-poly N,N-dimethylamino-2-ethyl methacrylate) (PLA-b-PDMAEMA). The quaternized PDMAEMA segment not only works as a compatibilizer between hydrophilic CMC and hydrophobic PLA, but
Madeshwaran Sekkarapatti Ramasamy et al.
Journal of colloid and interface science, 455, 63-70 (2015-06-10)
The synthesis of self-doped conducting polypyrrole-grafted graphene sheets (GS-PPy) for non-volatile memory applications is reported. First, the alkyne-modified graphene sheets (GS-alkyne) were covalently functionalized with a water-soluble polymer containing numerous anionic SO3(-) dopants by a copper-catalyzed click reaction. Then, polypyrrole
J A Redondo et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 90, 38-43 (2014-12-03)
In this work, the cationic monomer N-ethyl pyrrolidine methacrylamide (EPA) was copolymerized with the neutral monomer N-hydroxypropyl methacrylamide (HPMA) at different molar ratios obtaining linear random copolymers that were characterized and evaluated in vitro as non-viral gene carriers using murine
Kai Luo et al.
Journal of chromatography. A, 1379, 51-55 (2015-01-04)
While urinary 3-hydroxybenzo[a]pyrene (3-OHBaP) can indicate exposure to carcinogenic benzo[a]pyrene (BaP) in humans, most previous analytical methods could not detect it in the general population due to a lack of sufficient sensitivity. In this study, a new liquid chromatography-electrospray mass-mass
Anton Airinei et al.
International journal of molecular sciences, 12(9), 6176-6193 (2011-10-22)
Novel polythioetherimides bearing azobenzene moieties were synthesized from azobismaleimides and bis-2-mercaptoethylether. Kinetics of trans-cis photoisomerization and of thermal conversion of cis to trans isomeric forms were investigated in both polymer solution and poly(methyl methacrylate) doped films using electronic absorption spectroscopy.
István Ilisz et al.
Journal of pharmaceutical and biomedical analysis, 98, 130-139 (2014-06-09)
Procedures for the direct high-performance liquid chromatographic enantiomer separation of four bicyclo[2.2.2]octane-based 3-amino-2-carboxylic acids were developed in polar-ionic mode on zwitterionic chiral stationary phases (CSPs) based on cinchonane alkaloide quinine, quinidine and chiral sulfonic acid motifs. The effects of the
Yang Shu et al.
Journal of chromatography. A, 1390, 50-61 (2015-03-17)
Three cyclofructan-based, two glycopeptide-based, and one zwitterionic column used in the HILIC mode were assessed within a graphical framework based on different functional characteristics contributing to selectivity. The characteristics of these six HILIC columns are put in the perspective of
Anshul Sharma et al.
Macromolecular bioscience, 15(2), 200-214 (2014-10-11)
Here we report on the modular synthesis and characterization of biodegradable, controlled porous, liquid crystal elastomers (LCE) and their use as three-dimensional cell culture scaffolds. The elastomers were prepared by cross-linking of star block-co-polymers with pendant cholesterol units resulting in
Georgeta Coneac et al.
AAPS PharmSciTech, 16(4), 889-904 (2015-01-17)
The aim of the present investigation was to develop and evaluate microemulsion-loaded hydrogels (MEHs) for the topical delivery of fluconazole (FZ). The solubility of FZ in oils, surfactants and cosurfactants was evaluated to identify the components of the microemulsion. The
Hyun Wook Huh et al.
Carbohydrate polymers, 126, 130-140 (2015-05-03)
A biomineralized hydrogel system containing hyaluronic acid (HA) and poloxamer composed of a poly(ethylene oxide)/poly(propylene oxide)/poly(ethylene oxide) (PEO-PPO-PEO) block copolymer was developed as a biomimetic thermo-responsive injectable hydrogel system for bone regeneration. Using HA and poloxamer macromers with polymerizable residues
Jafer Vali Shaik et al.
Journal of chromatographic science, 52(7), 646-653 (2013-07-13)
A novel, specific and stability-indicating reversed-phase (RP) ultra-high-performance liquid chromatography (UHPLC) method, which is mass compatible, was developed and validated for the quantitative determination of silodosin and its related substances. Silodosin was subjected to stress conditions like hydrolysis (acid and
Huijuan Zhang et al.
Journal of drug targeting, 23(6), 552-567 (2015-03-11)
Artemisinin (ART) is a kind of drug with an endoperoxide bridge which tends to react with Fe(2+) to generate radicals for killing cancer cells. However, simultaneous delivery of hydrophobic ART and Fe(2+) ions into cancer cells remains a major challenge.
Le Ngoc Tran et al.
Journal of chromatography. A, 1396, 140-147 (2015-04-22)
A weak anion-exchanger chiral selector, quinine-incorporated silica/zirconia hybrid monolithic (QUI-S/ZHM) capillary column was prepared by sol-gel technology. The performance of the QUI-S/ZHM column was investigated for enantioresolution of a set of acidic chiral drugs and dinitrobenzoyl (DNB)-amino acids by capillary
J Jeong et al.
Domestic animal endocrinology, 52, 82-89 (2015-05-02)
Apolipoprotein D (APOD) is a glycoprotein which is widely expressed in mammalian tissues. It is structurally and functionally similar to the lipocalins which are multiple lipid-binding proteins that transport hydrophobic ligands and other small hydrophobic molecules, including cholesterol and several
Yuji Teramura
Biomaterials, 48, 119-128 (2015-02-24)
Intercellular interactions are important in the development, immune responses, and functions of tissues and organs. Few methods are currently available for experimentally inducing and analysing cell-cell interaction in vitro. Here I propose a method to induce cell-cell attachment by cell
Zhao et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 6(5), 843-848 (2000-05-29)
The vinylation of iodobenzene with methyl acrylate has been studied with several supported palladium catalysts in N-methylpyrrolidone in the presence of triethylamine and/or sodium carbonate. The reaction can be performed in air without any solubilizing or activating ligands. It was
Younis Baqi et al.
Molecules (Basel, Switzerland), 17(3), 2599-2615 (2012-03-07)
MG 50-3-1 (3, trisodium 1-amino-4-{4-[4-chloro-6-(2-sulfophenylamino)-1,3,5-triazin-2-ylamino]-2-sulfophenylamino}-9,10-dioxo-9,10-dihydroanthracene 2-sulfonate) is the most potent and selective antagonist (IC₅₀ 4.6 nM) for "P2Y₁-like" nucleotide-activated membrane receptors in guinea-pig taenia coli responsible for smooth muscle relaxation. Full characterization of the compound, however, e.g., at the human
Umadevi V Wesley et al.
Molecular neurobiology, 51(3), 1530-1541 (2014-08-03)
Sphingomyelin synthase (SMS) is a key enzyme involved in the generation of sphingomyelin (SM) and regulation of cell growth and survival. However, the effects of SMS on neuronal cell proliferation and cell cycle progression are not completely elucidated. In this
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