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Showing 1-30 of 50 results for "96-76-4" within Papers
F Ducray et al.
Neurology, 72(2), 156-161 (2009-01-14)
alpha-Internexin (INA) is a proneural gene encoding a neurofilament interacting protein that is upregulated in some gliomas, particularly oligodendrogliomas. INA expression was evaluated by immunohistochemistry in a series of 122 gliomas, and correlated to the 1p19q codeletion, a favorable prognostic
Mariko Matsumoto et al.
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences, (129)(129), 68-75 (2012-01-21)
A chemical category is a group of chemicals whose toxicological properties are expected to be similar or follow a regular pattern as a result of structural similarity. The category approach is beneficial for decreasing in the resource of risk assessment
Wendy Pollock et al.
Journal of immunological methods, 347(1-2), 19-23 (2009-06-06)
Most laboratories screen for antineutrophil cytoplasmic antibodies (ANCA) with indirect immunofluorescence (IIF) and confirm cytoplasmic (C-ANCA) and perinuclear (P-ANCA) staining with ELISAs for proteinase 3 (PR3) and myeloperoxidase (MPO) specificities. This study determined the concordance of ANCA test results from
Peiguo G Chu et al.
The American journal of surgical pathology, 26(8), 978-988 (2002-08-10)
Hepatocyte monoclonal antibody (Hep) (alternatively Hep Par 1 for Hep paraffin 1) has been reported to stain normal hepatic tissue and hepatocellular carcinoma (HCC) with high specificity. We have studied the Hepatocyte expression in 96 cases of HCC and 311
C Labbé-Jullié et al.
Endocrinology, 131(4), 1999-2009 (1992-10-01)
To compare the structural topology of the human TSH to that of the structurally related gonadotropins, 10 peptides covering the entire primary sequence of the alpha- and beta-subunits of TSH were synthesized and used as antigens for the preparation of
W G Chung et al.
Japanese journal of pharmacology, 84(2), 213-220 (2000-12-29)
Rat and human liver microsomes oxidized ranitidine to its N-oxide (66-76%) and S-oxide (13-18%) and desmethylranitidine (12-16%). N- and S-oxidations of ranitidine were inhibited by metimazole [flavin-containing monooxygenase (FMO) inhibitor] to 96-97% and 71-85%, respectively, and desmethylation of ranitidine was
Norbert Niederle et al.
Annals of hematology, 92(5), 653-660 (2013-01-24)
Bendamustine demonstrated clinical activity in pre-treated hematological malignancies due to its unique mechanism of action distinct from standard alkylating agents. This study assessed its efficacy in patients with chronic lymphocytic leukemia pre-treated with an alkylator, in comparison to fludarabine. Patients
Ashley R Schick et al.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 29(3), 239-245 (2019-04-18)
To calculate a risk prediction model for hemangiosarcoma (HSA) diagnosis in dogs presenting with nontraumatic hemoabdomen. Retrospective multicenter observational cohort study enrolling dogs presented 2003-2016. Five academic veterinary medical centers. A total of 406 dogs with nontraumatic hemoabdomen as the
Heimo H Wenzl et al.
Digestive diseases and sciences, 60(5), 1414-1423 (2014-11-09)
Many patients with quiescent Crohn's disease are maintained on long-term treatment with azathioprine (AZA), but controlled data are limited. We aimed to evaluate the efficacy of AZA therapy for more than 4 years to maintain clinical remission. We performed a
François Raffi et al.
The Lancet. Infectious diseases, 13(11), 927-935 (2013-10-01)
In the primary analysis of SPRING-2 at week 48, dolutegravir showed non-inferior efficacy to and similar tolerability to raltegravir in adults infected with HIV-1 and naive for antiretroviral treatment. We present the 96 week results. SPRING-2 is an ongoing phase
Won Joon Seong et al.
The journal of obstetrics and gynaecology research, 41(11), 1715-1720 (2015-10-01)
In the present study, we aimed to assess the biomarkers in mid-trimester cervical fluid that can predict early stage cervical shortening. We obtained cervical swab specimens from 96 gravidas, after which the cervical length was measured, at approximately 20 weeks of
U Haug et al.
British journal of cancer, 96(9), 1329-1334 (2007-04-05)
Stool testing based on tumour-derived markers might offer a promising approach for non-invasive colorectal cancer (CRC) screening. The aim of this study was to estimate the potential of a new test for faecal tumour M2-PK to discriminate patients with CRC
Sharon D Whatley et al.
The Journal of investigative dermatology, 127(12), 2790-2794 (2007-06-29)
Erythropoietic protoporphyria (EPP) is an inherited cutaneous porphyria characterized by partial deficiency of ferrochelatase (FECH), accumulation of protoporphyrin IX in erythrocytes, skin, and liver, and acute photosensitivity. Genetic counseling in EPP requires identification of FECH mutations, but current sequencing-based procedures
K W Harder et al.
The Biochemical journal, 298 ( Pt 2), 395-401 (1994-03-01)
The intracellular domain of human protein tyrosine phosphatase beta (HPTP beta) (44 kDa) was expressed in bacteria, purified using epitope 'tagging' immunoaffinity chromatography, and characterized with respect to kinetic profile, substrate specificity and potential modulators of enzyme activity. A chromogenic
C J Word et al.
International immunology, 1(3), 296-309 (1989-01-01)
The entire nucleotide sequence (approximately 20 kbp) spanning the human immunoglobulin IgM (mu) and IgD (delta) heavy chain constant region genes has been determined from DNA of mu-delta producing chronic lymphocytic leukemic B cells. As in the murine IgM +
Michael T Furlong et al.
Journal of pharmaceutical and biomedical analysis, 70, 574-579 (2012-06-20)
Carvedilol is widely prescribed for the treatment of hypertension, heart failure and left ventricular dysfunction following myocardial infarction. A sensitive and reliable liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay was developed and validated to enable reliable and efficient bioanalysis of the
Nigel W Brown et al.
Therapeutic drug monitoring, 38(1), 50-58 (2016-01-15)
A liquid chromatography-tandem mass spectrometric (LC-MS/MS) method was developed for routine measurement of ribavirin concentrations in EDTA-anticoagulated plasma. After protein precipitation, we used a bridged ethylene hybrid (hydrophilic interaction) chromatography column, 0.1 mmol/L ammonium formate pH 3.0, and a gradient
Jacqueline Bachofner et al.
Swiss medical weekly, 148, w14560-w14560 (2018-01-30)
The introduction of direct acting antivirals (DAAs) for the therapy of chronic hepatitis C (CHC) has revolutionised treatment and marks a paradigm shift in the approach to this disease, rendering interferon-based therapies obsolete. We retrospectively and prospectively evaluated treatment results
Yan Zheng et al.
Omics : a journal of integrative biology, 13(4), 301-306 (2009-07-25)
Differentiated embryo-chondrocyte expressed gene 1 (DEC1), as a bHLH transcriptional factor, plays important roles in cell differentiation, proliferation, and apoptosis. The expression of DEC1 and its role in human gastric cancer are unknown. This study was designed to characterize the
K Martínez et al.
Journal of chromatography. A, 879(1), 27-37 (2000-06-28)
A new method for the simultaneous determination of antifouling pesticides and some of their byproducts such as dichlofluanid, diuron and its byproducts [demethyldiuron and 1-(3,4-dichlorophenyl)urea], (2-thiocyanomethylthio)ben: zothiazole, chlorothalonil, Sea-nine 211, Irgarol 1051 and one of its byproducts (2-methylthio-4-tert.-butylamino-s-triazine) in seawater
Emad Hamdy et al.
Journal of laparoendoscopic & advanced surgical techniques. Part A, 25(6), 460-464 (2015-05-08)
Achalasia is an incurable primary motor disorder of the esophagus. The best treatment modality for achalasia is still controversial. This study compared the short- and intermediate-term outcome between endoscopic pneumatic dilatation (EPD) versus laparoscopic esophageal myotomy (LEM) for the management
S-W Tang et al.
Journal of clinical pharmacy and therapeutics, 37(5), 588-593 (2012-02-18)
The pathogenic mechanism of antituberculosis drug-induced hepatotoxicity (ATDH) is thought to involve drug-metabolizing enzymes including N-acetyl transferase2 (NAT2), cytochrome P4502E1 (CYP2E1) and glutathione S-transferase (GST) M1, T1. The associations between genetic polymorphisms of those genes and ATDH have been reported
Harold E Bays et al.
The American journal of cardiology, 108(5), 682-690 (2011-06-21)
AMR101 is an omega-3 fatty acid agent containing ≥96% eicosapentaenoic acid ethyl ester and no docosahexaenoic acid. Previous smaller studies suggested that highly purified eicosapentaenoic acid lowered triglyceride (TG) levels without increasing low-density lipoprotein (LDL) cholesterol levels. TG-lowering therapies such
J A Schneider et al.
Stroke, 36(5), 954-959 (2005-03-19)
Studies investigating the relation of the apolipoprotein E (apoE) epsilon4 allele to clinical stroke and to vascular changes on magnetic resonance imaging have been conflicting. Little data are available regarding the relation of apoE epsilon4 to cerebral infarctions documented on
XiaoFei Li et al.
Atherosclerosis, 218(1), 83-89 (2011-05-25)
Inflammation plays a crucial role in plaque vulnerability. Calcifications can be detected by means of in vivo imaging techniques. The study purpose is to assess a potential association between tissue localization of calcifications and the inflammatory biomarkers, C-reactive protein (CRP)
David Gonzalez et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 29(16), 2223-2229 (2011-04-13)
TP53 mutations have been described in chronic lymphocytic leukemia (CLL) and have been associated with poor prognosis in retrospective studies. We aimed to address the frequency and prognostic value of TP53 abnormalities in patients with CLL in the context of
Philip E Greilich et al.
Journal of cardiothoracic and vascular anesthesia, 29(2), 303-310 (2014-12-24)
High-quality prospective trials of hemostatic "rescue" therapy to control massive bleeding in cardiac surgery are lacking. Wide variability in the care of patients with severe bleeding following cardiopulmonary bypass has precluded accurate comparison of treatment groups in previous studies. This
Knut Brockow et al.
The Journal of allergy and clinical immunology, 135(4), 977-984 (2014-10-02)
Oral wheat plus cofactors challenge tests in patients with wheat-dependent exercise-induced anaphylaxis (WDEIA) produce unreliable results. We sought to confirm WDEIA diagnosis by using oral gluten flour plus cofactors challenge, to determine the amount of gluten required to elicit symptoms
Stefan Santen et al.
International journal of colorectal disease, 25(9), 1063-1070 (2010-07-02)
Leukocyte recruitment is a key feature in ischemia-reperfusion (I/R)-induced tissue injury. The aim of the present study was to investigate the effect of Rho-kinase inhibition on I/R-provoked leukocyte recruitment in the colon. C57BL/6 mice were subjected to 30 min of
E Shiigi et al.
Journal of bone and mineral metabolism, 19(5), 308-311 (2001-08-11)
Ossification of spinal ligaments (OSL) is a common form of myelopathy characterized by heterotopic bone formation in the spinal ligaments, predominantly in men. Although the etiology of OSL is not fully understood, previous studies have strongly suggested the involvement of
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