Search Within
A7460
Applied Filters:
Keyword:'A7460'
Showing 1-30 of 296 results for "A7460" within Papers
Tae Hoon Kwon et al.
Molecules and cells, 38(7), 616-623 (2015-05-28)
P2 receptors are membrane-bound receptors for extracellular nucleotides such as ATP and UTP. P2 receptors have been classified as ligand-gated ion channels or P2X receptors and G protein-coupled P2Y receptors. Recently, purinergic signaling has begun to attract attention as a
Hiroko Kita-Matsuo et al.
PloS one, 4(4), e5046-e5046 (2009-04-09)
Developmental, physiological and tissue engineering studies critical to the development of successful myocardial regeneration therapies require new ways to effectively visualize and isolate large numbers of fluorescently labeled, functional cardiomyocytes. Here we describe methods for the clonal expansion of engineered
Angels Ruyra et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 182, 55-63 (2014-12-24)
The zebrafish (Danio rerio) is a widely used model species for biomedical research and is also starting to be a model for aquaculture research. The ZFL cell line, established from zebrafish liver, has been mostly used in toxicological and ecotoxicological
Anna Poltronieri et al.
La Medicina del lavoro, 101(6), 403-408 (2010-12-15)
Hairdressers are exposed to irritants and allergenic compounds that may cause contact dermatitis, rhinitis and asthma. In this paper we describe the case of a female, age 33 years, who developed contact dermatitis after 10 years of exposure to ammonium
M Vergara-BarberƔn et al.
Food chemistry, 169, 28-33 (2014-09-23)
The improvement of protein extraction from olive leaves using an enzyme-assisted protocol has been investigated. Using a cellulase enzyme (CelluclastĀ® 1.5L), different parameters that affect the extraction process, such as the influence and amount of organic solvent, enzyme amount, pH
Jessica R Ingram et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(36), E4975-E4984 (2015-08-26)
Calcium-dependent protein kinases (CDPKs) comprise the major group of Ca2+-regulated kinases in plants and protists. It has long been assumed that CDPKs are activated, like other Ca2+-regulated kinases, by derepression of the kinase domain (KD). However, we found that removal
Sae Jeong Park et al.
American journal of cancer research, 5(7), 2127-2138 (2015-09-04)
S-adenosylhomocysteine hydrolase (AHCY) hydrolyzes S-adenosylhomocysteine to adenosine and l-homocysteine, and it is already known that inhibition of AHCY decreased cell proliferation by G2/M arrest in MCF7 cells. However, the previous study has not indicated what mechanism the cell cycle arrest
Yong-Woo Kim et al.
Materials science & engineering. C, Materials for biological applications, 95, 86-94 (2018-12-24)
Human skin exhibits high stiffness of up to 100āÆMPa and high toughness of up to 3600āÆJāÆm-2 despite its high water content of 40-70āÆwt%. Engineering hydrogels have rarely possessed both high stiffness and toughness, because compliant hydrogels usually become brittle when
Donghee Lee et al.
Langmuir : the ACS journal of surfaces and colloids, 31(35), 9684-9693 (2015-08-14)
The stiffness of the extracellular matrix (ECM) plays an important role in controlling cell functions. As an alternative to the ECM, hydrogels of tunable elasticity are widely used for in vitro cell mechanobiology studies. Therefore, characterizing the Young's modulus of
Beate Schwer et al.
RNA (New York, N.Y.), 21(6), 1135-1146 (2015-04-18)
Protein phosphatases regulate mRNA synthesis and processing by remodeling the carboxy-terminal domain (CTD) of RNA polymerase II (Pol2) to dynamically inscribe a Pol2 CTD code. Fission yeast Fcp1 (SpFcp1) is an essential 723-amino acid CTD phosphatase that preferentially hydrolyzes Ser2-PO4
Siegfried Wagner et al.
Anticancer research, 35(1), 145-148 (2015-01-01)
Canine prostate cancer (PC) is a highly aggressive malignancy. However, in contrast to man, neither standard screening strategies nor curative therapeutic options exist for the companion animal. A prostate-specific membrane antigen (PSMA) screening as molecular marker akin to human PC
Maree T Smith et al.
Journal of pharmaceutical sciences, 104(7), 2388-2396 (2015-05-23)
This study was designed to assess the analgesic efficacy and systemic exposure of oxycodone administered topically in a novel tocopheryl phosphate mixture (TPM) gel formulation, to the inflamed hindpaws in a rat model of inflammatory pain. Unilateral hindpaw inflammation was
Ali Nematollahzadeh et al.
Journal of chromatography. A, 1345, 154-163 (2014-05-03)
In the present work, we report a novel method for the reinforcement of hierarchically structured molecularly imprinted polymer (MIP) for the separation of human serum albumin (HSA) and immunoglobulin G (IgG) proteins under pressure driven flow conditions. The template proteins
Fuchao Xu et al.
Journal of chromatography. A, 1401, 33-41 (2015-05-23)
A multi-residue analytical method was developed for the determination of a range of flame retardants (FRs), including polybrominated diphenyl ethers (PBDEs), emerging halogenated FRs (EFRs) and organophosphate FRs (PFRs), in food matrices. An ultrasonication and vacuum assisted extraction (UVAE), followed
Xiuzhen Zhu et al.
Electrophoresis, 36(13), 1507-1513 (2014-11-05)
Electrophoresis and dielectrophoresis of cells can reveal many distinct cellular properties but are often conducted separately. Herein a simultaneous strategy was proposed, and a simple method was established by making cells migrate through a cross channel under a micro video
Il Young Choi et al.
Angewandte Chemie (International ed. in English), 54(36), 10497-10501 (2015-06-20)
A new method to develop two-dimensional PANI nanosheets using ice as a removable hard template is presented. Distinctly high current flows of 5.5ā
mA at 1ā
V and a high electrical conductivity of 35ā
Sācm(-1) were obtained for the polyaniline (PANI) nanosheets, which
Micky Fu Xiang Lee et al.
Journal of chromatography. A, 1394, 71-80 (2015-04-04)
A thermo-responsive random copolymer, POEGMA (poly(oligoethylene glycol) methacrylate) grafted on cationized agarose adsorbent was used for size selective protein adsorption. The effects of OEGMA300 ((oligoethylene glycol) methyl ether methacrylate, Mn=300g/mol) content and temperature on the adsorption of bovine serum albumin
Madeshwaran Sekkarapatti Ramasamy et al.
Journal of colloid and interface science, 455, 63-70 (2015-06-10)
The synthesis of self-doped conducting polypyrrole-grafted graphene sheets (GS-PPy) for non-volatile memory applications is reported. First, the alkyne-modified graphene sheets (GS-alkyne) were covalently functionalized with a water-soluble polymer containing numerous anionic SO3(-) dopants by a copper-catalyzed click reaction. Then, polypyrrole
Apeng Chen et al.
Analytica chimica acta, 887, 230-236 (2015-09-01)
Toward developing a micro HPLC cartridge, we have recently built a high-pressure electroosmotic pump (EOP). However, we do not recommend people to use this pump to deliver an organic solvent directly, because it often makes the pump rate unstable. We
Christian Franck et al.
PloS one, 6(3), e17833-e17833 (2011-04-07)
The interactions between biochemical processes and mechanical signaling play important roles during various cellular processes such as wound healing, embryogenesis, metastasis, and cell migration. While traditional traction force measurements have provided quantitative information about cell matrix interactions in two dimensions
Juliana Ben et al.
Neurochemical research, 39(12), 2492-2500 (2014-10-16)
The epileptogenesis process involves cell signaling events associated with neuroplasticity. The mitogen-activated protein kinases (MAPKs) integrate signals originating from a variety of extracellular stimuli and may regulate cell differentiation, survival, cell death and synaptic plasticity. Here we compared the total
Ailing Teo et al.
Journal of biomechanics, 48(10), 1777-1781 (2015-06-09)
Embryonic stem cells (ESCs) grow into three-dimensional (3D) spheroid structures en-route to tissue growth. In vitro spheroids can be controllably induced on a two-dimensional (2D) substrate with high viability. Here we use a method for inducing pluripotent embryoid body (EB)
Biomineralized biomimetic organic/inorganic hybrid hydrogels based on hyaluronic acid and poloxamer.
Hyun Wook Huh et al.
Carbohydrate polymers, 126, 130-140 (2015-05-03)
A biomineralized hydrogel system containing hyaluronic acid (HA) and poloxamer composed of a poly(ethylene oxide)/poly(propylene oxide)/poly(ethylene oxide) (PEO-PPO-PEO) block copolymer was developed as a biomimetic thermo-responsive injectable hydrogel system for bone regeneration. Using HA and poloxamer macromers with polymerizable residues
Rajeev Kumar Kapoor et al.
Bioresource technology, 189, 99-106 (2015-04-16)
Laccases have wide range of substrate specificity and find applications from pulp industry to waste water remediation. Laccases have also been used in combined pretreatment of biomass hydrolyzates to remove enzymatic and fermentation inhibitors. In this study, laccase production by
Anna Labernadie et al.
Nature communications, 5, 5343-5343 (2014-11-12)
Podosomes are adhesion structures formed in monocyte-derived cells. They are F-actin-rich columns perpendicular to the substrate surrounded by a ring of integrins. Here, to measure podosome protrusive forces, we designed an innovative experimental setup named protrusion force microscopy (PFM), which
Loreen R Stromberg et al.
Journal of microbiological methods, 116, 1-7 (2015-06-21)
Certain Shiga toxin-producing Escherichia coli (STEC) are virulent human pathogens that are most often acquired through contaminated food. The United States Department of Agriculture, Food Safety and Inspection Service has declared several serogroups of STEC as adulterants in non-intact raw
Asif Khurshid Qazi et al.
Cancer letters, 359(1), 47-56 (2015-01-03)
Deregulation of PI3K signalling pathway is strongly involved in pathology of cancer and development of resistance in tumour cells. Here, we report that pharmacologically active vasicinone analogue, RLX (7, 8, 9, 10-Tetrahydroazepino [2, 1-b] quinazolin-12-(6H)-on), exhibited potent anticancer activities both
CĆ©line Labouesse et al.
Biophysical journal, 108(10), 2437-2447 (2015-05-21)
The mechanical interaction between adherent cells and their substrate relies on the formation of adhesion sites and on the stabilization of contractile acto-myosin bundles, or stress fibers. The shape of the cell and the orientation of these fibers can be
Senem Ćulha et al.
Materials science & engineering. C, Materials for biological applications, 52, 315-324 (2015-05-09)
L-Lysine imprinted poly(2-hydroxyethyl methacrylate-co-N-methacryloyl-L-aspartic acid) [P(HEMA-co-MAAsp)] cryogels were synthesized and characterized with Fourier transform infrared spectroscopy, scanning electron microscopy, surface area measurements, swelling, and squeezing tests. Specific surface area for imprinted cryogel was 34.2m(2)/g while the value was 21.3m(2)/g for
Aurore Masson et al.
Scientific reports, 5, 16898-16898 (2015-11-19)
Today, Light Sheet Fluorescence Microscopy (LSFM) makes it possible to image fluorescent samples through depths of several hundreds of microns. However, LSFM also suffers from scattering, absorption and optical aberrations. Spatial variations in the refractive index inside the samples cause
Page 1 of 10