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Showing 1-30 of 79 results for "A89855" within Papers
Alison E Mahan et al.
Journal of immunological methods, 417, 34-44 (2014-12-20)
The N-glycan of the IgG constant region (Fc) plays a central role in tuning and directing multiple antibody functions in vivo, including antibody-dependent cellular cytotoxicity, complement deposition, and the regulation of inflammation, among others. However, traditional methods of N-glycan analysis
Interaction of anthranilic acid with silver nanoparticles: A Raman, surface-enhanced Raman scattering and density functional theoretical study.
Chadha R, et al.
Journal of Molecular Structure, 1076, 35-41 (2014)
Emilien Foureau et al.
Current genetics, 58(4), 245-254 (2012-05-24)
Candida guilliermondii is an interesting biotechnological model for the industrial production of value-added metabolites and also remains an opportunistic emerging fungal agent of candidiasis often associated with oncology patients. The aim of the present study was to establish a convenient
P Calandra
Acta vitaminologica et enzymologica, 29(1-6), 158-160 (1975-01-01)
The pattern of tryptophan metabolites "via kynurenine" was determined in the epidermis of man and mouse using semiquantitative method of one- and two-dimensional thin-layer-chromatography. In the epidermis of healthy man the following metabolites were present: tryptophan, kynurenine, anthranilic acid, 3-hydroxyanthranilic
Anne Staudt Kvistgaard et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 73, 59-70 (2014-07-30)
Lacprodan® OPN-10 is a proprietary whey-based protein product that contains bovine-derived osteopontin (OPN), found in human milk and other bodily tissues. In vitro genotoxicity tests conducted according to accepted guidelines at up to 5000μg/plate OPN failed to induce genetic mutations
Daiki Asakawa et al.
Journal of the American Society for Mass Spectrometry, 24(2), 297-300 (2013-01-12)
MALDI in-source decay (ISD) has been used for top-down sequencing of proteins. The use of the matrix 1,5-diaminonapthalene (1,5-DAN) gave abundant w ions, which are formed from the unimolecular dissociation of z• radical fragments via α cleavage reaction and thus
Raza Rasool et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 148, 435-443 (2015-05-09)
New metal polychelates of Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) obtained by the interaction of metal acetates with polymeric Schiff base containing formaldehyde and piperazine, have been investigated. Structural and spectroscopic properties have been evaluated by elemental analysis, FT-IR and
Generation of 9(10H)-Acridone from Anthranilic Acid.
Ho TL and Jou DG.
J. Chin. Chem. Soc., 48(1), 81-82 (2001)
Umang V Shah et al.
Pharmaceutical research, 32(1), 248-259 (2014-07-20)
Surface area and surface energy of pharmaceutical powders are affected by milling and may influence formulation, performance and handling. This study aims to decouple the contribution of surface area and surface energy, and to quantify each of these factors, on
Wenjun Zhou et al.
Brain, behavior, and immunity, 46, 147-153 (2015-02-01)
Chronic pain frequently co-occurs with major depressive disorder but the mechanisms are poorly understood. We investigated the contribution of indoleamine 2,3-dioxygenase-1 (IDO1), a rate-limiting enzyme in the conversion of tryptophan to neurotoxic metabolites, to this comorbidity using the spared nerve
Katsumi Shibata et al.
Bioscience, biotechnology, and biochemistry, 79(1), 103-108 (2014-09-26)
The conversion of tryptophan (Trp) → nicotinamide (Nam) is an important pathway for supplying vitamin niacin. We reported the following two phenomena: (1) severe food restriction led to an increase in the Trp → Nam conversion compared with free-access control
Marisa Möller et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 898, 121-129 (2012-05-23)
It is highly beneficial to monitor the activity of the kynurenine pathway in a large series of samples with high accuracy and reliability in a single experimental protocol. We have developed a rapid specific solid-phase extraction (SPE)-liquid chromatography-electrospray ionization tandem
Jiangbei Yuan et al.
Analytical biochemistry, 462, 1-9 (2014-06-10)
A novel strategy is proposed, using cost-saving chemical reactions to generate intact free reducing N-glycans and their fluorescent derivatives from glycoproteins for subsequent analysis. N-Glycans without core α-1,3-linked fucose are released in reducing form by selective hydrolysis of the N-type
Chiaki Hiratsuka et al.
Journal of nutritional science and vitaminology, 60(4), 255-260 (2014-10-10)
We have previously reported that dietary supplementation with up to 5.0 g/d of L-tryptophan (L-Trp) for 21 d has no adverse effects, judging from the levels of general blood variables, in healthy women. We performed a randomized, double-blind, placebo-controlled, crossover
Heiko Niewerth et al.
Journal of bacteriology, 195(5), 1068-1080 (2013-01-01)
The genes coding for quinaldine catabolism in Arthrobacter sp. strain Rue61a are clustered on the linear plasmid pAL1 in two upper pathway operons (meqABC and meqDEF) coding for quinaldine conversion to anthranilate and a lower pathway operon encoding anthranilate degradation
Luisa Rios-Avila et al.
The Journal of nutrition, 143(9), 1509-1519 (2013-08-02)
Vitamin B-6 deficiency is associated with impaired tryptophan metabolism because of the coenzyme role of pyridoxal 5'-phosphate (PLP) for kynureninase and kynurenine aminotransferase. To investigate the underlying mechanism, we developed a mathematical model of tryptophan metabolism via the kynurenine pathway.
Verena J Koller et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 80, 130-136 (2015-03-21)
Synthetic cannabinoids (SCs) cause similar effects as cannabis and are sold in herbal mixtures. Recent investigations indicate that some of these drugs possess genotoxic properties. Therefore, we tested representatives of two groups, namely, aminoalkylindoles (AM-2201 and UR-144) and 1-alkylindazoles (5F-AKB-48
Jae-Suk Choi et al.
Biological & pharmaceutical bulletin, 37(12), 1963-1970 (2014-12-03)
Rice bran oil extracted by supercritical CO2 extraction (RB-SCE) reportedly exhibits pharmacological activities such as antioxidant and in vivo hair growth-inducing effects. Such activities raise the possibility of the development of novel hair growth-inducing agents using RB-SCE. The aim of
Hiroyuki Yamashita et al.
Pharmaceutical research, 31(8), 1946-1957 (2014-02-14)
The advent of cocrystals has demonstrated a growing need for efficient and comprehensive coformer screening in search of better development forms, including salt forms. Here, we investigated a coformer screening system for salts and cocrystals based on binary phase diagrams
Amal Abdel Haleem Mohamed Eissa et al.
Chemical & pharmaceutical bulletin, 60(10), 1290-1300 (2012-08-07)
Simple, three classes of new anthranilic acid derivatives were aimed at, synthesized and tested for their toxicity, anti-inflammatory, analgesic, antipyretic activity. Also, their potential protective role against ulcerative colitis in rats was performed. Furthermore, their effect on liver and kidney
Mehmet Karabacak et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 96, 644-656 (2012-08-09)
This study presents the structural and spectroscopic characterization of 3,5-dibromoanthranilic acid with help of experimental techniques (FT-IR, FT-Raman, UV, NMR) and quantum chemical calculations. The vibrational spectra of title compound were recorded in solid state with FT-IR and FT-Raman in
David C A Neville et al.
Journal of chromatography. A, 1233, 66-70 (2012-03-07)
Hydrophilic interaction liquid chromatography (HILIC) of fluorescently labelled oligosaccharides is used in many laboratories to analyse complex oligosaccharide mixtures. Separations are routinely performed using a TSK gel-Amide 80 HPLC column, and retention times of different oligosaccharide species are converted to
C H Little et al.
Archives of environmental health, 54(1), 6-14 (1999-02-20)
Twenty patients proved sensitive to a 15-min exposure to 15 ppm toluene. We assessed patients neuropsychologically before and after toluene exposure, and they had impaired cognitive functioning characterized by a deterioration in short- and long-term memory and psychomotor coordination. We
Eri Nishiyama et al.
FEMS microbiology letters, 330(1), 46-55 (2012-03-01)
In our recent screen for soil-induced genes, the expression of andA operon (andAcAdAbAa) for anthranilate catabolism in Burkholderia multivorans ATCC 17616 was found to increase dramatically in a soil sample (Nishiyama et al., Environ Microbiol 12: 2539, 2010). The operon was
M R Ritchie et al.
European journal of clinical nutrition, 58(9), 1286-1289 (2004-04-01)
To study the variation in genistein + daidzein intake over a 6-month period and test the reliability of 24 h urinary isoflavones as a biomarker of exposure over time. Dietary genistein + daidzein intake was assessed at various time points
Jun Soma et al.
Nephron, 92(3), 693-698 (2002-10-10)
Tranilast, N-(3,4-dimethoxycinnamoyl) anthranilic acid, suppresses collagen synthesis by various cells, including macrophages and fibroblasts, by interfering with the actions of transforming growth factor-beta 1. We investigated the effect of tranilast on progression of diabetic nephropathy (DN), since this process is
M F Alves et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 38(6), 861-868 (2005-06-04)
A continuous assay using internally quenched fluorescent peptides with the general sequence Abz-peptidyl-(Dnp)P-OH (Abz = ortho-aminobenzoic acid; Dnp = 2,4-dinitrophenyl) was optimized for the measurement of angiotensin I-converting enzyme (ACE) in human plasma and rat tissues. Abz-FRK(Dnp)P-OH, which was cleaved
Chiaki Hiratsuka et al.
The Journal of nutrition, 143(6), 859-866 (2013-04-26)
Because of the frequent use of L-tryptophan (L-Trp) in dietary supplements, determination of the no-observed-adverse-effect-level is desirable for public health purposes. We therefore assessed the no-observed-adverse-effect-level for L-Trp and attempted to identify a surrogate biomarker for excess L-Trp in healthy
A A M Belal et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 149, 771-787 (2015-05-20)
The main target of this paper is to get an interesting data for the preparation and characterizations of metal oxide (MO) nanoparticles using H2L Schiff base complexes as precursors through the thermal decomposition procedure. Five Schiff base complexes of Mn(II)
Hans F N Kvitvang et al.
Analytical chemistry, 83(7), 2705-2711 (2011-03-11)
Metabolite profiling methods are important tools for measurement of metabolite pools in biological systems. While most metabolite profiling methods report relative intensities or depend on a few internal standards representing all metabolites, the ultimate requirement for a quantitative description of
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