Search Within


Applied Filters:
Showing 1-30 of 45 results for "AB911" within Papers
Dean S Carson et al.
Addiction biology, 15(4), 448-463 (2010-08-25)
Recent preclinical evidence indicates that the neuropeptide oxytocin may have potential in the treatment of drug dependence and drug withdrawal. Oxytocin reduces methamphetamine self-administration, conditioned place preference and hyperactivity in rodents. However, it is unclear how oxytocin acts in the
Joe Eun Son et al.
Science advances, 7(44), eabh4503-eabh4503 (2021-10-28)
[Figure: see text].
Pryscila D S Teixeira et al.
Journal of neuroendocrinology, 32(2), e12818-e12818 (2019-11-30)
Neurones expressing the melanin-concentrating hormone (MCH) can be found in the medial preoptic area (mPOA) and ventral aspects of the periventricular preoptic nucleus of rats by mid-to-late lactation and this expression disappears after weaning. The transitory expression of MCH in
Hailan Liu et al.
The Journal of comparative neurology, 529(9), 2362-2375 (2020-12-29)
Vitamin D action has been linked to several diseases regulated by the brain including obesity, diabetes, autism, and Parkinson's. However, the location of the vitamin D receptor (VDR) in the brain is not clear due to conflicting reports. We found
Haruki Nishimura et al.
Frontiers in endocrinology, 11, 43-43 (2020-03-03)
Various types of acute/chronic nociceptive stimuli cause neuroendocrine responses such as activation of the hypothalamo-neurohypophysial [oxytocin (OXT) and arginine vasopressin (AVP)] system and hypothalamo-pituitary adrenal (HPA) axis. Chronic multiple-arthritis activates the OXT/AVP system, but the effects of acute mono-arthritis on
Feng-Qin He et al.
IBRO neuroscience reports, 11, 164-174 (2021-11-09)
Exercise can reduce the incidence of stress-related mental diseases, such as depression and anxiety. Control group was neither exposed to CVMS nor TRE (noCVMS/noTRE). Females were tested and levels of serum17-beta-oestradiol (E2), estrogen receptors α immunoreactive neurons (ERα-IRs), estrogen receptors
Leqiang Sun et al.
Molecular neurodegeneration, 14(1), 8-8 (2019-02-10)
Neurotropic virus-based tracers have been extensively applied in mapping and manipulation of neural circuits. However, their neurotropic and neurotoxic properties remain to be fully characterized. Through neural circuit tracing, we systematically compared the neurotropism discrepancy among different multi-trans-synaptic and mono-synaptic
Fengqin He et al.
The European journal of neuroscience, 47(1), 95-108 (2017-12-06)
Oestrogen has both anxiogenic and anxiolytic effects because of variation in opposing action on alpha (ERα) and beta (ERβ) estrogen receptors in the medial preoptic area (mPOA), bed nucleus of the stria terminalis (BNST) and medial amygdala (MeA). Oxytocin (OT)
Eric R Schuppe et al.
The Journal of comparative neurology, 530(6), 903-922 (2021-10-07)
Neuropeptides, including oxytocin-like peptides, are a conserved group of hormones that regulate a wide range of social behaviors, including vocal communication. In the current study, we evaluate whether putative brain sites for the actions of isotocin (IT), the oxytocin (OT)
Mehwish Anwer et al.
Journal of neurotrauma, 37(7), 924-938 (2019-10-28)
Traumatic brain injury (TBI) causes damage to the hypothalamo-hypophyseal axis, leading to endocrine dysregulation in up to 40% of TBI patients. Hence, there is an urgent need to identify non-invasive biomarkers for TBI-associated hypothalamo-hypophyseal pathology. Sushi repeat-containing protein X-linked 2
Amanda Holley et al.
Physiology & behavior, 196, 78-83 (2018-08-24)
Although female rats are typically described as having a promiscuous mating strategy, if sexually naïve females have their formative sexually rewarding experiences paired with the same male, they will recognize that male and display mate-guarding behavior towards him in the
Omprakash Singh et al.
Brain structure & function, 225(9), 2775-2798 (2020-11-04)
This study tested the hypothesis whether hypothalamic cocaine-and amphetamine-regulated transcript (CART)-containing systems were involved in photoperiod-induced responses associated with spring migration (hyperphagia and weight gain) and reproduction (gonadal maturation) in migratory songbirds. We specifically chose CART to examine neural mechanism(s) underlying
Jianbo Liu et al.
Frontiers in neuroscience, 15, 634781-634781 (2021-02-27)
Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders characterized by impaired skills in social interaction and communication in addition to restricted and repetitive behaviors. Many different factors may contribute to ASD development; in particular, oxytocin receptor (OXTR) deficiency
Mahasweta Das et al.
The Journal of comparative neurology, 500(4), 761-776 (2006-12-13)
The hypothalamic paraventricular nucleus (PVN) coordinates major neuroendocrine and behavioral mechanisms, particularly responses to homeostatic challenges. Parvocellular and magnocellular PVN neurons are richly innervated by pituitary adenylate cyclase-activating polypeptide (PACAP) axons. Our recent functional observations have also suggested that PACAP
D Zelena et al.
Journal of neuroendocrinology, 25(8), 711-718 (2013-05-10)
Adult male Brattleboro rats were used to investigate the impact of the congenital absence of vasopressin on the release pattern of oxytocin (OXT) within the hypothalamic supraoptic nucleus (SON) in response to a 10-min forced swimming session and osmotic stimulation.
Sarah J Baracz et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 47(8), 1561-1573 (2022-05-18)
Early life stress (ELS) is associated with perturbed neural development and augmented vulnerability to mental health disorders, including addiction. How ELS changes the brain to increase addiction risk is poorly understood, and there are no therapies which target this ELS-induced
E V Farina et al.
Anatomia, histologia, embryologia, 43(2), 159-163 (2013-04-05)
Many studies have demonstrated the physiological effects of oxytocin (OT), atrial natriuretic peptide (ANP) and vasopressin (VP) in the homoeostasis of body fluids during physical exercise. However, a little information is available about the related immunohistochemical changes in hypothalamic magnocellular
Karin Warfvinge et al.
The journal of headache and pain, 21(1), 10-10 (2020-02-08)
Recent work, both clinical and experimental, suggests that the hypothalamic hormone oxytocin (OT) and its receptor (OTR) may be involved in migraine pathophysiology. In order to better understand possible central actions of OT in migraine/headache pathogenesis, we mapped the distribution
María Pilar Madrigal et al.
Communications biology, 4(1), 586-586 (2021-05-16)
Oxytocin (OXT) and arginine vasopressin (AVP) support a broad range of behaviors and homeostatic functions including sex-specific and context-appropriate social behaviors. Although the alterations of these systems have been linked with social-related disorders such as autism spectrum disorder, their formation
Aleisha M Moore et al.
Scientific reports, 9(1), 14768-14768 (2019-10-16)
Neurons in the hypothalamic arcuate nucleus (ARC) that co-express kisspeptin, neurokinin B and dynorphin (KNDy cells) are essential for mammalian reproduction as key regulators of gonadotropin-releasing hormone (GnRH) secretion. Although multiple endogenous and exogenous signals act indirectly via KNDy neurons
Brigitta Bonaldo et al.
European journal of histochemistry : EJH, 65(s1) (2021-11-11)
Bisphenol A (BPA), an organic synthetic compound found in some plastics and epoxy resins, is classified as an endocrine disrupting chemical. Exposure to BPA is especially dangerous if it occurs during specific "critical periods" of life, when organisms are more
Han Kyoung Choe et al.
Neuron, 87(1), 152-163 (2015-07-04)
Meaningful social interactions modify behavioral responses to sensory stimuli. The neural mechanisms underlying the entrainment of neutral sensory stimuli to salient social cues to produce social learning remain unknown. We used odor-driven behavioral paradigms to ask if oxytocin, a neuropeptide
Nicole Denoix et al.
Frontiers in medicine, 9, 925433-925433 (2022-07-19)
The hydrogen sulfide (H2S) and the oxytocin/oxytocin receptor (OT/OTR) systems interact in the central nervous and cardiovascular system. As a consequence of osmotic balance stress, H2S stimulates OT release from the paraventricular nuclei (PVN) in the hypothalamic regulation of blood
Paula G F Quaresma et al.
The Journal of comparative neurology, 529(6), 1228-1239 (2020-08-28)
Multiple neuroendocrine, autonomic and behavioral responses are regulated by the paraventricular nucleus of the hypothalamus (PVH). Previous studies have shown that PVH neurons express the growth hormone (GH) receptor (GHR), although the role of GH signaling on PVH neurons is
S Higo et al.
Journal of neuroendocrinology, 28(4) (2015-12-29)
The neuropeptide kisspeptin and its receptor play an essential role in reproduction as a potent modulator of the gonadotrophin-releasing hormone (GnRH) neurone. In addition to its reproductive function, kisspeptin signalling is also involved in extra-hypothalamic-pituitary-gonadal (HPG) axis systems, including oxytocin
Yu-Ting Lin et al.
Nature communications, 8(1), 537-537 (2017-09-16)
In addition to the regulation of social and emotional behaviors, the hypothalamic neuropeptide oxytocin has been shown to stimulate neurogenesis in adult dentate gyrus; however, the mechanisms underlying the action of oxytocin are still unclear. Taking advantage of the conditional
Silvana Valtcheva et al.
Nature, 621(7980), 788-795 (2023-09-21)
Oxytocin is a neuropeptide that is important for maternal physiology and childcare, including parturition and milk ejection during nursing1-6. Suckling triggers the release of oxytocin, but other sensory cues-specifically, infant cries-can increase the levels of oxytocin in new human mothers7
Hao-Cheng Chang et al.
The Journal of biological chemistry, 299(1), 102728-102728 (2022-11-22)
Haploinsufficiency in retinoic acid induced 1 (RAI1) causes Smith-Magenis syndrome (SMS), a severe neurodevelopmental disorder characterized by neurocognitive deficits and obesity. Currently, curative treatments for SMS do not exist. Here, we take a recombinant adeno-associated virus (rAAV)-clustered regularly interspaced short
DLK1 is a somato-dendritic protein expressed in hypothalamic arginine-vasopressin and oxytocin neurons.
Villanueva, C; Jacquier, S; de Roux, N
Testing null
Ting-Bei Bo et al.
The ISME journal, 14(10), 2625-2645 (2020-07-08)
Many small mammals engage in coprophagy, or the behavior of consuming feces, as a means to meet nutritional requirements when feeding on low-quality foods. In addition to nutritional benefits, coprophagy may also help herbivores retain necessary gut microbial diversity and
Page 1 of 2