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Showing 1-30 of 160 results for "BCA1" within Papers
Hui Zhang et al.
Thoracic cancer, 6(2), 172-179 (2015-08-15)
To determine the relationship between FOXN1 (a transcription factor) and B cell-attracting chemokine 1 (BCA1, a chemotactic factor), and their influence on thymoma cell proliferation. We initially used immunohistochemical methods to compare the expression levels of FOXN1 and BCA1 in
D Jantas et al.
Neurotoxicity research, 25(2), 208-225 (2013-10-10)
Tianeptine (Tian) possesses neuroprotective potential, however, little is known about the effect of this drug in models of neuronal apoptosis. In the present study, we aimed (1) to compare the neuroprotective capacities of some antidepressants (ADs) in the models of
Milvija Plazibat et al.
The FEBS journal, 287(21), 4783-4800 (2020-02-15)
Antiepileptic/teratogen valproate (VPA) is a histone deacetylase inhibitor/epigenetic drug proposed for the antitumor therapy where it is generally crucial to target poorly or undifferentiated cells to prevent a recurrence. Transplanted rodent gastrulating embryos-proper (primitive streak and three germ layers) are
Zhitao Gong et al.
Journal of neuroinflammation, 18(1), 203-203 (2021-09-17)
We have recently showed that atorvastatin (ATO) combined with low dose of dexamethasone (DEX) was more efficacious in treating patients with chronic subdural haematoma (CSDH) than ATO monotherapy. This study was designed to investigate the underlying mechanisms of the improved
Involvement of double-stranded RNA-dependent protein kinase and antisense viral RNA in the constitutive NFĪŗB activation in adult T-cell leukemia/lymphoma cells.
S Kinpara et al.
Leukemia, 29(6), 1425-1429 (2015-01-09)
Alex Ismail et al.
FEBS letters, 591(1), 137-144 (2016-12-08)
Rat perivascular adipose tissue (PVAT) stores, takes up, and releases norepinephrine (NE; Ayala-Lopez et al. (2014) Pharmacol Res Perspect 2, e00041). We hypothesized that 3T3-L1 adipocytes would exhibit similar behaviors and, thus, could serve as a model for PVAT adipocytes.
Federica Geddo et al.
Nutrients, 13(3) (2021-04-04)
Skeletal muscle plays a pivotal role in whole-body glucose metabolism, accounting for the highest percentage of glucose uptake and utilization in healthy subjects. Impairment of these key functions occurs in several conditions including sedentary lifestyle and aging, driving toward hyperglycemia
Gabriela KrejÄovĆ” et al.
eLife, 8 (2019-10-15)
Macrophage-mediated phagocytosis and cytokine production represent the front lines of resistance to bacterial invaders. A key feature of this pro-inflammatory response in mammals is the complex remodeling of cellular metabolism towards aerobic glycolysis. Although the function of bactericidal macrophages is
Daorong Hou et al.
Transgenic research (2021-10-29)
Uncoupling protein 1 (UCP1) was found exclusively in the inner membranes of the mitochondria of brown adipose tissue (BAT). We found that UCP1 was also expressed in heart tissue and significantly upregulated in isoproterenol (ISO)-induced acute myocardial ischemia (AMI) rat
Hong-Wei Zhang et al.
Journal of cellular and molecular medicine, 25(8), 3699-3713 (2021-02-24)
MicroRNA-24-3p (miR-24-3p) has been implicated as a key promoter of chemotherapy resistance in numerous cancers. Meanwhile, cancer-associated fibroblasts (CAFs) can secret exosomes to transfer miRNAs, which mediate tumour development. However, little is known regarding the molecular mechanism of CAF-derived exosomal
Christopher Donovan et al.
Translational vision science & technology, 10(9), 25-25 (2021-08-24)
To evaluate the use of genipin in delaying enzymatic digestion of corneal stroma. Human corneal stromal tissue was treated with genipin, a known chemical crosslinker, and then along with control tissue was subjected to enzymatic digestion with collagenase. The effects
Annette Wiegand et al.
Caries research, 53(6), 636-642 (2019-06-05)
This study aimed to analyse if the erosion-protective potential of the salivary pellicle is different between female and male subjects. Bovine enamel and dentin specimens (each nĀ = 3) were exposed to the oral cavity of healthy female or male volunteers
David J Ferland et al.
PloS one, 15(2), e0229251-e0229251 (2020-02-25)
Since chemerin's identification as an adipokine, it has been associated with a number of human diseases including diabetes and obesity. However, the basic scientific foundation for these clinical determinations is still lacking. Fibroblastic mouse 3T3 cells are unable to develop
Katie E Marshall et al.
The Journal of experimental biology, 221(Pt 15) (2018-06-14)
Internal ice formation leads to wholesale changes in ionic, osmotic and pH homeostasis, energy metabolism, and mechanical damage, across a small range of temperatures, and is thus an abiotic stressor that acts at a distinct, physiologically relevant, threshold. Insects that
Yogesh Bhattarai et al.
Physiological reports, 2(10) (2014-10-31)
Large conductance Ca(2+)-activated K(+) (BK) channels consist of pore-forming Ī±- and accessory Ī²-subunits. There are four Ī²-subunit subtypes (Ī²1-Ī²4), BK Ī²1-subunit is specific for smooth muscle cells (SMC). Reduced BK Ī²1-subunit expression is associated with SMC dysfunction in animal models
TGFB1 modulates in vitro secretory activity and viability of equine luteal cells
Galvao A, et al.
Cytokine, 110, 316-327 (2018)
David J Ferland et al.
The Journal of pharmacology and experimental therapeutics, 365(2), 212-218 (2018-02-23)
Chemerin is an inflammatory adipokine positively associated with hypertension and obesity. The majority of chemerin derives from the liver and adipose tissue, however, their individual contributions to blood pressure are unknown. We began studying chemerin in the normal rat using
Vladimir GrubiÅ”iÄ et al.
Cell reports, 32(10), 108100-108100 (2020-09-10)
Mechanisms resulting in abdominal pain include altered neuro-immune interactions in the gastrointestinal tract, but the signaling processes that link immune activation with visceral hypersensitivity are unresolved. We hypothesized that enteric glia link the neural and immune systems of the gut
Magnus Karlsson et al.
International journal of cancer, 127(3), 729-736 (2009-12-05)
Powerful analytical tools are vital for characterizing the complex molecular changes underlying oncogenesis and cancer treatment. This is particularly true, if information is to be collected in vivo by noninvasive approaches. In the recent past, hyperpolarized (13)C magnetic resonance (MR)
Seyedsina Moeinzadeh et al.
Advanced biosystems, 1(3) (2017-03-01)
The objective of this work was to investigate the effect of devitalized human mesenchymal stem cells (hMSCs) and endothelial colony-forming cells (ECFCs) seeded on mineralized nanofiber microsheets on protein release, osteogenesis, vasculogenesis, and macrophage polarization. Calcium phosphate nanocrystals were grown
Zhiwei Chen et al.
PloS one, 8(11), e79725-e79725 (2013-11-19)
Ionic liquid pretreatment of biomass has been shown to greatly reduce the recalcitrance of lignocellulosic biomass, resulting in improved sugar yields after enzymatic saccharification. However, even under these improved saccharification conditions the cost of enzymes still represents a significant proportion
E Gefen et al.
Journal of evolutionary biology, 24(10), 2110-2117 (2011-06-24)
Lower Nahal Oren in Northern Israel, often referred to as 'Evolution Canyon', has been proposed as a microscale model site for ecological evolution. However, conflicting stress resistance and mating assay results contribute to controversy over the Nahal Oren model. In
Federico Iseppon et al.
Journal of biological methods, 4(1), e65-e65 (2017-03-07)
Local stimulation with optical tweezers has been used to mimic natural stimuli that occur in biological processes such as cell migration or differentiation. Carriers (beads and lipid vesicles) with sizes down to 30 nm can be manipulated with a high
Belal Mosaferi et al.
Scientific reports, 11(1), 22941-22941 (2021-11-27)
The gut-microbiota-brain axis plays an important role in stress-related disorders, and dysfunction of this complex bidirectional system is associated with Alzheimer's disease. This study aimed to assess the idea that whether gut microbiota depletion from early adolescence can alter anxiety-
Nadia Ayala-Lopez et al.
American journal of physiology. Heart and circulatory physiology, 309(11), H1904-H1914 (2015-10-04)
Perivascular adipose tissue (PVAT) reduces vasoconstriction to norepinephrine (NE). A mechanism by which PVAT could function to reduce vascular contraction is by decreasing the amount of NE to which the vessel is exposed. PVATs from male Sprague-Dawley rats were used
Lucie CrƩpin et al.
Applied and environmental microbiology, 83(5) (2017-01-25)
During fermentative growth in natural and industrial environments, Saccharomyces cerevisiae must redistribute the available nitrogen from multiple exogenous sources to amino acids in order to suitably fulfill anabolic requirements. To exhaustively explore the management of this complex resource, we developed
Carlos Moreno-Yruela et al.
Nature communications, 12(1), 62-62 (2021-01-06)
Histones control gene expression by regulating chromatin structure and function. The posttranslational modifications (PTMs) on the side chains of histones form the epigenetic landscape, which is tightly controlled by epigenetic modulator enzymes and further recognized by so-called reader domains. Histone
S A Follows et al.
Infection and immunity, 77(9), 3602-3610 (2009-06-24)
Several microbial pathogens can modulate the host apoptotic response to infection, which may contribute to immune evasion. Various studies have reported that infection with the sexually transmitted disease pathogen Neisseria gonorrhoeae can either inhibit or induce apoptosis. N. gonorrhoeae infection
Stephanie W Watts et al.
Pharmacology research & perspectives, 3(1), e00103-e00103 (2015-02-19)
Serotonin (5-HT, 5-hydroxytryptamine) reduces blood pressure of the conscious rat when administered chronically (1Ā week). 5-HT does not directly relax isolated arteries, and microsphere experiments in 5-HT-infused rats suggested that 5-HT increased flow to the splanchnic bed. We hypothesized that 5-HT
NatƔlia Bonissi GonƧalves et al.
Clinics (Sao Paulo, Brazil), 73, e150-e150 (2018-11-01)
Dietary omega-3 fatty acids have been efficacious in decreasing serum cholesterol levels and reducing the risk of cardiovascular disease. However, the metabolic and molecular changes induced by the omega-3 fatty acid Ī±-linolenic acid (ALA), which is found in linseed oil
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