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Showing 1-30 of 105 results for "C0768" within Papers
Zahra Mehraban et al.
Journal of cellular biochemistry, 120(10), 17250-17257 (2019-05-29)
Alteration of free radicals (reactive oxygen species) causes mammals' sperm damage. Gallic acid (GA) is known as an antioxidant which is effective against oxidative stress. The purpose of this study was to evaluate the antioxidant effects of GA on the
[Treatment of advanced Hodgkin lymphoma].
S Kreissl et al.
Deutsche medizinische Wochenschrift (1946), 138(23), 1212-1214 (2013-05-31)
Participant-level data and the new frontier in trial transparency.
Deborah A Zarin
The New England journal of medicine, 369(5), 468-469 (2013-08-02)
Thomas Clapes et al.
Nature cell biology, 23(7), 704-717 (2021-07-14)
Haematopoietic stem cells (HSCs) are normally quiescent, but have evolved mechanisms to respond to stress. Here, we evaluate haematopoietic regeneration induced by chemotherapy. We detect robust chromatin reorganization followed by increased transcription of transposable elements (TEs) during early recovery. TE
J Tammam et al.
British journal of pharmacology, 158(5), 1183-1195 (2009-09-25)
gamma-Secretase inhibitors (GSIs) block NOTCH receptor cleavage and pathway activation and have been under clinical evaluation for the treatment of malignancies such as T-cell acute lymphoblastic leukaemia (T-ALL). The ability of GSIs to decrease T-ALL cell viability in vitro is
Aaron D Mickle et al.
Nature, 565(7739), 361-365 (2019-01-04)
The fast-growing field of bioelectronic medicine aims to develop engineered systems that can relieve clinical conditions by stimulating the peripheral nervous system1-5. This type of technology relies largely on electrical stimulation to provide neuromodulation of organ function or pain. One
An atoll variant that mocks.
Francis X McCormack et al.
American journal of respiratory and critical care medicine, 188(1), 110-110 (2013-07-03)
Yi-Hu Zheng et al.
Phytotherapy research : PTR, 28(9), 1342-1348 (2014-03-07)
The therapeutic potential of baicalein against hepatoma cells was evaluated in vitro and in vivo. In cell viability assays, baicalein showed significant cytotoxicity against the hepatocellular carcinoma cell lines H22, Bel-7404, and Hep G2 and moderate cytotoxicity against immortalized human
S Chaabouni et al.
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 17(3), 229-232 (2013-05-15)
The extranodal non-Hodgkin lymphomas of maxillofacial soft tissues are rare. We report two cases of maxillofacial soft tissue non-Hodgkin lymphoma treated with chemotherapy followed by localized radiotherapy with complete remission after 3 and 6 months. We study the clinical, radiological
Thomas Colley et al.
Antimicrobial agents and chemotherapy, 62(5) (2018-02-15)
The antifungal effects of the novel triazole PC1244, designed for topical or inhaled administration, against Aspergillus fumigatus were tested in a range of in vitro and in vivo studies. PC1244 demonstrated potent antifungal activities against clinical A. fumigatus isolates (n
Carlos Alexandre Lutterbeck et al.
Chemosphere, 135, 403-410 (2015-05-24)
Anti-cancer drugs are compounds that are of high environmental relevance because of their lack of specific mode of action. They can be extremely harmful to living organisms even at low concentrations. The present study evaluated the toxic effects of four
STAT3 mediates multidrug resistance of Burkitt lymphoma cells by promoting antioxidant feedback
Zeng R, et al.
Biochemical and biophysical research communications, 488(1), 182-188 (2017)
No Soo Kim et al.
Journal of ethnopharmacology, 241, 112025-112025 (2019-06-13)
A rhizome of Phragmites communis Trinius has been used in traditional medicine to remove a heat, relieve vomiting and fever, nourish body fluids, and treat diseases like cancers. However, the safety of Phragmitis rhizoma has not yet been fully assessed.
Veenu Tripathi et al.
Oncogene, 38(17), 3185-3200 (2019-01-11)
Transforming growth factor-β (TGF-β) is major inducer of epithelial-to-mesenchymal transition (EMT), which associates with cancer cell metastasis and resistance to chemotherapy and targeted drugs, through both transcriptional and non-transcriptional mechanisms. We previously reported that, in cancer cells, heightened mitogenic signaling
Shubin Li et al.
Journal of ovarian research, 14(1), 17-17 (2021-01-23)
This study investigated the effect of recombinant human lactoferrin (rhLF) on the premature ovarian failure (POF) of rats. After cyclophosphamide treatments, the POF rats were divided into the following groups: normal control group (NC), low-dose group (LD), medium-dose group (MD)
Tuğba Ekiz Yılmaz et al.
Acta histochemica, 122(2), 151470-151470 (2019-12-10)
Cyclophosphamide (CYP) is one of the alkylating chemotherapeutic agents and its adverse effects on folliculogenesis in the ovary are well-known due to the previous scientific research on this topic. Magnesium has various effects in organisms, including catalytic functions on the
Jared L Crandon et al.
Antimicrobial agents and chemotherapy, 59(5), 2688-2694 (2015-02-26)
The combination of cefepime with AAI101, a novel extended-spectrum β-lactamase inhibitor, possesses potent in vitro activity against many resistant Gram-negative pathogens. Against a panel of 20 mostly carbapenemase-producing cefepime-nonsusceptible strains of the family Enterobacteriaceae, we evaluated the MICs of cefepime
Jaslyn Sian-Siu Soo et al.
Apoptosis : an international journal on programmed cell death, 20(10), 1373-1387 (2015-08-16)
Metformin, an AMPK activator, has been reported to improve pathological response to chemotherapy in diabetic breast cancer patients. To date, its mechanism of action in cancer, especially in cancer stem cells (CSCs) have not been fully elucidated. In this study
Wei Cui et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(7), 1036-1040 (2013-07-16)
To explore the inhibitory effect of combined administration of bear bile powder (BBP) and cyclophosphamide (Cytoxan, CTX) on colorectal cancer liver metastasis by regulating tumor promotion inflammation microenvironment. The CRC liver metastasis mode in mice was established through in situ
Immunosuppressive effect of cyclophosphamide on white blood cells and lymphocyte subpopulations from peripheral blood of Balb/c mice
Huyan XH, et al.
International Immunopharmacology, 11(9), 1293-1297 (2011)
Genevieve M Weir et al.
Oncoimmunology, 3(8), e953407-e953407 (2014-01-01)
In clinical trials, metronomic cyclophosphamide (CPA) is increasingly being combined with vaccines to reduce tumor-induced immune suppression. Previous strategies to modulate the immune system during vaccination have involved continuous administration of low dose chemotherapy, studies that have posed unique considerations
A case of primary skull lymphoma: review of literature.
Sudhansu Sekhar Mishra et al.
Neurology India, 61(3), 334-336 (2013-07-19)
Metronomic cyclophosphamide activation of anti-tumor immunity: tumor model, mouse host, and drug schedule dependence of gene responses and their upstream regulators
Wu J, et al.
BMC Cancer, 16(1), 623-623 (2016)
Light chain deposition.
Cyrus C Hsia et al.
Blood, 121(26), 5111-5111 (2013-08-24)
Phedias Diamandis et al.
Nature chemical biology, 3(5), 268-273 (2007-04-10)
The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways that governs the
Wei Li et al.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 33(2), 233-237 (2013-06-26)
To explore the inhibitory effect of Zishenshengxue capsule (ZSC) on myelosuppression in mice induced by cyclophosphamide. Kunming mice were randomly assigned into a control group, myelosuppression group, or groups for mice with myelosuppression receiving high dose ZSC, middle dose ZSC
Elna Fernandes et al.
Chemosphere, 261, 127678-127678 (2020-07-28)
The rise of cancer cases worldwide led to an increase in production and consumption of anticancer drugs, that ultimately end up in the marine environment and are accumulated in aquatic organisms. Cyclophosphamide (CP) is a cytotoxic alkylating agent frequently prescribed
Jennifer L Guerriero et al.
Journal of immunology (Baltimore, Md. : 1950), 186(6), 3517-3526 (2011-02-09)
Dysregulation of apoptosis is associated with the development of human cancer and resistance to anticancer therapy. We have previously shown in tumor xenografts that DNA alkylating agents induce sporadic cell necrosis and regression of apoptosis-deficient tumors. Sporadic tumor cell necrosis
Susmita Kundu et al.
The Indian journal of chest diseases & allied sciences, 55(1), 49-52 (2013-06-27)
We report a case of a 42-year-old patient who presented with Wegener's granulomatosis complicated by pulmonary renal syndrome, i.e., diffuse alveolar haemorrhage and rapidly progressive crescentic glomerulonephritis. The patient was treated with plasmapheresis and immunosuppressive drugs--intravenous cyclophosphamide and methyl prednisolone.
L V Filatova et al.
Voprosy onkologii, 59(2), 59-65 (2013-07-03)
In a retrospective study during the primary mode MOPP to primary patients LH II/IVAB stages with a poor prognosis rate of CR, 5--and 10-year DFS, OS was 69%, 71% and 68%, 74% and 64%, ABVD--76%, 78%, 83% and 68%, BEACOPP-baseline--73%
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