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Showing 1-30 of 40 results for "C0990000" within Papers
Brian D Fitz et al.
Journal of chromatography. A, 1392, 82-90 (2015-03-31)
Low thermal mass gas chromatography (LTM-GC) was evaluated for rapid, high peak capacity separations with three injection methods: liquid, headspace solid phase micro-extraction (HS-SPME), and direct vapor. An Agilent LTM equipped with a short microbore capillary column was operated at
Flávia C Carvalho et al.
Journal of pharmaceutical sciences, 99(5), 2367-2374 (2009-12-08)
The development of a controlled-release dosage form of zidovudine (AZT) is of crucial importance, in view of the pharmacokinetics of its toxic activity. A suitable drug delivery system could increase AZT bioavailability, reducing its dose-dependent side effects. In this study
Mohamed Sellami et al.
BMC biotechnology, 11, 68-68 (2011-06-21)
Waxes are esters of long-chain fatty acids and long-chain alcohols. Their principal natural sources are animals (sperm whale oil) and vegetables (jojoba) which are expensive and not easily available. Wax esters synthesized by enzymatic transesterification, using palm stearin as raw
Nermeen Adel ElKasabgy et al.
International journal of pharmaceutics, 472(1-2), 369-379 (2014-07-01)
Lipotomes were designed to enhance lacidipine's oral bioavailability by improving its solubility and enhancing the oral lymphatic uptake. Lipotomes were prepared using cetyl alcohol and Tween(®) 80 using a thin film hydration technique. Cetyl alcohol was chosen for imparting a
Rehab Nabil Shamma et al.
Pharmaceutical development and technology, 17(5), 583-593 (2011-07-21)
Sustained release matrix pellets of the freely water soluble drug, betahistine dihydrochloride (BH), were prepared using freeze pelletization technique. Different waxes and lipids (cetyl alcohol, beeswax, glyceryl tripalmitate (GTP) and glyceryl tristearate) were evaluated for the preparation of matrix pellets.
Dhanalakshmi S Anbukumar et al.
Journal of lipid research, 51(5), 1085-1092 (2009-12-19)
Neutrophils are important in the host response against invading pathogens. One chemical defense mechanism employed by neutrophils involves the production of myeloperoxidase (MPO)-derived HOCl. 2-Chlorohexadecanal (2-ClHDA) is a naturally occurring lipid product of HOCl targeting the vinyl ether bond of
Sudarsan Biswal et al.
Acta pharmaceutica (Zagreb, Croatia), 59(2), 199-210 (2009-07-01)
The purpose of the study was to evaluate the suitability of laboratory scale spheronizer for the production of spherical pellets loaded with diltiazem hydrochloride by wax combination. The 1:1 combination of cetyl alcohol and hydrogenated castor oil, as low and
Mahmoud Mokhtar Ibrahim et al.
Drug development and industrial pharmacy, 40(6), 765-773 (2013-04-11)
In this study, unilamellar liposomal vesicles of diltiazem HCl (DH) were prepared using either reversed phase evaporation (REV) or proliposome methods. Soya phosphatidylcholine (SPC) was used for preparing the liposomes, and the vesicles were rigidified using cholesterol (Chol) or cetyl
M A Sheraz et al.
International journal of cosmetic science, 36(5), 494-504 (2014-07-30)
The present investigation is based on the formulation of water-in-oil (w/o) cream preparations of ascorbic acid (AA) at pH 4-6 using different emollients and humectants. The preparations were stored in the dark at 30°C for a period of 3 months and
Luca Lo Piccolo et al.
Applied and environmental microbiology, 77(4), 1204-1213 (2010-12-25)
Enzymes involved in oxidation of long-chain n-alkanes are still not well known, especially those in gram-positive bacteria. This work describes the alkane degradation system of the n-alkane degrader actinobacterium Gordonia sp. strain SoCg, which is able to grow on n-alkanes
Xiaoyu Wang et al.
Physical chemistry chemical physics : PCCP, 14(16), 5470-5478 (2012-03-15)
Myoglobin binding to the binary monolayers composed of sodium hexadecylimino diacetate and hexadecanol at the air-water interface by means of metal coordination has been investigated using infrared reflection absorption spectroscopy (IRRAS). In the absence of Cu(2+), no myoglobin binding to
Claire Gendre et al.
International journal of pharmaceutics, 453(2), 448-453 (2013-06-26)
Curing is generally required to stabilize film coating from aqueous polymer dispersion. This post-coating drying step is traditionally carried out in static conditions, requiring the transfer of solid dosage forms to an oven. But, curing operation performed directly inside the
Yunfei Sun et al.
International journal of pharmaceutics, 468(1-2), 83-90 (2014-04-09)
Gene therapy is a potent tool for the treatment of cancer and other gene defect diseases, which involves using DNA that encodes a functional, therapeutic gene to replace a mutated gene. However, the DNA transfection efficiency is restricted by its
James L Hargrove et al.
Experimental biology and medicine (Maywood, N.J.), 229(3), 215-226 (2004-02-28)
Very long chain fatty alcohols obtained from plant waxes and beeswax have been reported to lower plasma cholesterol in humans. This review discusses nutritional or regulatory effects produced by wax esters or aliphatic acids and alcohols found in unrefined cereal
T Yoshida et al.
International journal of pharmaceutics, 365(1-2), 81-88 (2008-09-16)
Salting-out effects were utilized for developing a multiparticulate system balancing numbness masking and high bioavailability. A "salting-out taste-masking system" consisting of a drug core containing acetaminophen as a model drug, a salting-out layer containing sodium carbonate (Na(2)CO(3)) and hydroxypropylmethylcellulose (HPMC)
Aly Ahmed Abdelbary et al.
Drug delivery, 22(1), 37-49 (2013-12-20)
Famotidine HCl has low bioavailability (40-45%) due to its narrow absorption window and low solubility in intestinal pH. Lipids were utilized in the formulation of novel gastroretentive dosage forms to increase the availability of famotidine HCl at its absorption site.
Laurent Perge et al.
International journal of pharmaceutics, 422(1-2), 59-67 (2011-10-27)
A hot melt dispersion method was used to prepare new sustained release ibuprofen composite microparticles of a solid lipid at ambient temperature, cetyl alcohol. The dispersion of colloidal silicon dioxide nanoparticles (hydrophilic Aerosil 200 or hydrophobic Aerosil R974) either in
T P Pyroh et al.
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993), 71(4), 9-14 (2009-11-27)
The hexadecane oxidation of Rhodococcus erythropolls EK-1 was established to be catalyzed by the alkane hydroxylase complex containing Fe-S proteid rubredoxin. Alkane hydroxylase activity was increased twice in the presence of 10 mg/l iron ions in the cultivation medium. Sodium
Liping He et al.
Carbohydrate research, 348, 95-98 (2011-11-22)
The hydrophilic features of natural fibers (NFs) hinder the widespread application of natural fiber/polymer composites due to the hydroxyl groups (-OH) presented in the cellulose molecule. Detecting reactive hydroxyl groups in NFs is very important for optimizing the modification process
Jaleh Varshosaz et al.
Journal of liposome research, 24(3), 191-203 (2013-12-21)
Quercetin (QT) is a potential chemotherapeutic drug with low solubility that seriously limits its clinical use. The aim of this study was enhancing cellular penetration of QT by sterol containing solid lipid nanoparticles (SLNs) which make bilayers fluent for targeting
Allergic contact dermatitis from cetyl alcohol.
Angela E Aakhus et al.
Dermatitis : contact, atopic, occupational, drug, 22(1), 56-57 (2011-02-05)
Yoshinori Onuki et al.
Drug development and industrial pharmacy, 40(7), 937-943 (2013-05-02)
A non-destructive method for monitoring creaming of emulsion-based formulations is in great demand because it allows us to understand fully their instability mechanisms. This study was aimed at demonstrating the usefulness of magnetic resonance (MR) techniques, including MR imaging (MRI)
Yuanzhi Chen et al.
Small (Weinheim an der Bergstrasse, Germany), 11(12), 1460-1469 (2014-10-31)
The combination of metal and semiconductor components in nanoscale to form a hybrid nanocrystal provides an important approach for achieving advanced functional materials with special optical, magnetic and photocatalytic functionalities. Here, a facile solution method is reported for the synthesis
Shishu Goindi et al.
Journal of liposome research, 24(3), 249-257 (2014-03-22)
Levocetirizine, an active enantiomer of cetirizine is third generation antihistaminic agent used for treating various allergies like atopic dermatitis, chronic idiopathic urticaria and allergic rhinitis. Development of novel topical formulation of levocetirizine based on flexible vesicles (FVs) with an aim
W B Rizzo et al.
Journal of lipid research, 41(7), 1077-1081 (2000-07-07)
Sjögren-Larsson syndrome (SLS) is an inherited disorder associated with deficient oxidation of long-chain aliphatic alcohols. Previous studies have reported modest elevations in total (free + esterified) fatty alcohols in SLS, but free fatty alcohols have not been selectively measured, in
Katerina Dvorácková et al.
Drug development and industrial pharmacy, 35(8), 930-940 (2009-03-11)
The purpose of this experimental work was the development of hydrophilic-lipophilic matrix tablets for controlled release of slightly soluble drug represented here by diclofenac sodium (DS). Drug dissolution profile optimization provided by soluble filler was studied. Matrix tablets were based
Kerstin Wagner et al.
Chemistry and physics of lipids, 145(2), 119-127 (2006-12-26)
The monolayer structure of pure dipalmitoylphosphatidylcholine (DPPC) and equimolar mixtures of DPPC/n-hexadecanol (C(16)OH) and DPPC/dipalmitoylglycerol (DPG) are studied by the film balance technique and grazing incidence X-ray diffraction measurements. At 20 degrees C, the binary systems exhibit complete miscibility. In
Benjawan Boonkaew et al.
Burns : journal of the International Society for Burn Injuries, 40(8), 1562-1569 (2014-04-29)
A novel burn wound hydrogel dressing has been previously developed which is composed of 2-acrylamido-2-methylpropane sulfonic acid sodium salt with silver nanoparticles (silver AMPS). This study compared the cytotoxicity of this dressing to the commercially available silver products; Acticoat™, PolyMem
Marcos Luciano Bruschi et al.
Drug development and industrial pharmacy, 34(3), 267-278 (2008-03-26)
Precursor systems of liquid crystalline phase were prepared using the surfactant PPG-5-Ceteth-20, isopropyl myristate, and water; gelatin microparticles containing propolis were then added into these systems. Homogeneity of dispersion, the in-system microparticle morphology, and sedimentation behavior of each formulation were
Neha Mittal et al.
Molecular and cellular biochemistry, 354(1-2), 113-122 (2011-04-05)
Surfactant plays an important role in lung homeostasis and is also involved in maintaining innate immunity within the lung. Lipopolysaccharide (LPS) is known to elicit acute proinflammatory responses in lung diseases such as acute respiratory distress syndrome and is responsible
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