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Showing 1-30 of 222 results for "C6745" within Papers
Meng Hu et al.
The Journal of pharmacology and experimental therapeutics, 351(1), 87-95 (2014-07-23)
Myofibroblasts are effector cells in fibrotic disorders that synthesize and remodel the extracellular matrix (ECM). This study investigated the role of the Src kinase pathway in myofibroblast activation in vitro and fibrogenesis in vivo. The profibrotic cytokine, transforming growth factor
A severe pulmonary complication in a patient with COL4A1-related disorder: A case report.
Abe Y, et al.
European Journal of Medical Genetics, 60(3), 169-171 (2017)
Surgery, 156(4), 908-909 (2014-09-23)
Alexander H Nave et al.
Arteriosclerosis, thrombosis, and vascular biology, 34(7), 1446-1458 (2014-05-17)
Pulmonary vascular remodeling, the pathological hallmark of pulmonary arterial hypertension, is attributed to proliferation, apoptosis resistance, and migration of vascular cells. A role of dysregulated matrix cross-linking and stability as a pathogenic mechanism has received little attention. We aimed to
Jun Shimizu et al.
Biochemical and biophysical research communications, 456(2), 626-630 (2014-12-17)
Oral supplementation with collagen hydrolysate (CH) has been shown to improve the condition of the skin in humans and experimental animals. Several hydroxyproline-containing oligo-peptides were previously detected in human peripheral blood after the ingestion of CH, and the two dipeptides
Jerome P Sullivan
Primary dental journal, 2(4), 49-55 (2014-01-29)
In the front of the mouth, the treatment of such a bony defect carries the risk of a poor aesthetic outcome. High patient expectations, combined with the difficulty of recreating a large mass of viable bone in which a dental
Alejandra Orihuel et al.
Food research international (Ottawa, Ont.), 125, 108622-108622 (2019-09-27)
The enterohemorrhagic Escherichia (E.) coli (EHEC) is a pathogen of great concern for public health and the meat industry all over the world. The high economic losses in meat industry and the high costs of the illness highlight the necessity
P Bainbridge
Journal of wound care, 22(8), 407-408 (2013-08-09)
Fibroblasts are critical in supporting normal wound healing, involved in key processes such as breaking down the fibrin clot, creating new extra cellular matrix (ECM) and collagen structures to support the other cells associated with effective wound healing, as well
Fabiano Ribeiro Cirano et al.
The Journal of oral implantology, 40(6), 655-659 (2014-12-17)
This study analyzed the role of recombinant human bone morphogenetic protein 2 (rhBMP-2) and recombinant human bone morphogenetic protein 7 (rhBMP-7) in the adhesion and differentiation of rat osteoblast-like (osteo-1) cells cultured on chemically modified titanium surfaces. Osteo-1 cells were
Morgan D Silldorff et al.
The Journal of bone and joint surgery. American volume, 96(20), e175-e175 (2014-10-17)
Injury to the supraspinatus and infraspinatus tendons and the associated atrophic changes to the muscle remain a common clinical problem. Specifically, increased muscle stiffness has been implicated in failure of the repair and poor functional outcomes. We present a comparison
Daehwan Kim et al.
International journal of cancer, 135(11), 2547-2557 (2014-04-18)
Discoidin domain receptors (DDRs) are unusual receptor tyrosine kinases (RTKs) that are activated by fibrillar collagens instead of soluble growth factors. DDRs play an important role in various cellular functions and disease processes, including malignant progression. Compared to other RTKs
Di Wu et al.
The Journal of biological chemistry, 289(49), 34033-34048 (2014-10-23)
We have reported previously that nonmuscle myosin II-interacting guanine nucleotide exchange factor (MyoGEF) plays an important role in the regulation of cell migration and cytokinesis. Like many other guanine nucleotide exchange factors (GEFs), MyoGEF contains a Dbl homology (DH) domain
Luigi Martino et al.
Nucleic acids research, 43(1), 645-660 (2014-12-10)
The La-related proteins (LARPs) form a diverse group of RNA-binding proteins characterized by the possession of a composite RNA binding unit, the La module. The La module comprises two domains, the La motif (LaM) and the RRM1, which together recognize
V K Il'in et al.
Vestnik Rossiiskoi akademii meditsinskikh nauk, (2)(2), 56-62 (2013-07-04)
Dysbiotic shifts in intestinal and pharyngeal microflora were studied in 22 normal volunteers in 9-, 14-, 105- and 520-d chamber experiments simulating some of the spaceflight factors. Two preparations were administered to prevent pharyngeal and intestinal dysbiosis: oral dry probiotic
Lin Xu et al.
PloS one, 6(5), e20282-e20282 (2011-06-10)
CD4(+)CD25(+) regulatory T cells (Tregs), a heterogeneous population, were enrichment in tumor mass and played an important role in modulating anti-tumor immunity. Recently, we reported a Treg subset, CCR6(+) Tregs but not CCR6(-)Tregs, were enriched in tumor mass and closely
Utilization of commercial collagens for preparing well-differentiated human beta cells for confocal microscopy.
Brennecke, et al.
Frontiers in Endocrinology, 14, 1187216-1187216 (2023)
Hui Xie et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 26(1), 156-168 (2010-06-26)
Recently, a membrane-based estrogen receptor (ER), ER-α36, was identified and cloned that transduces membrane-initiated estrogen signaling such as activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway. Here we show that the postmenopausal level of estradiol (E2) induces
U M D Lekshmi et al.
Pakistan journal of biological sciences : PJBS, 16(22), 1545-1550 (2014-02-12)
To assess the effects of antidiabetic drugs on collagen, the study has been carried out. However, at present, no conclusive data available on the In vivo effect of antidiabetic drugs in collagen. It was therefore thought worthwhile to undertake a
Wei Li et al.
Biochemical pharmacology, 89(3), 370-385 (2014-04-08)
Preeclampsia is a complication of pregnancy manifested as maternal hypertension and often fetal growth restriction. Placental ischemia could be an initiating event, but the linking mechanisms leading to hypertension and growth restriction are unclear. We have shown an upregulation of
Gayan S De Silva et al.
Surgery, 156(1), 183-189 (2014-05-27)
Biologic matrices used in abdominal wall reconstruction are purported to undergo remodeling into connective tissue resembling native collagen. Key steps in that process include inflammatory response at the mesh/tissue interface, cellular penetration, and neovascularization of the matrix, followed by fibroblast
Lucia Pulzova et al.
Scientific reports, 1, 86-86 (2012-02-23)
Lyme borreliosis is the most widespread vector-borne disease in temperate zones of Europe and North America. Although the infection is treatable, the symptoms are often overlooked resulting in infection of the neuronal system. In this work we uncover the underlying
Serafim Tsitsilonis et al.
Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons, 20(2), 94-99 (2014-05-07)
The effect of anabolic androgenic steroids on tendons has not yet been fully elucidated. Aim of the present study was the evaluation of the impact of anabolic androgenic steroids on the biomechanical and histological characteristics of Achilles tendons. Twenty-four male
Shaynoor Dramsi et al.
Microbes and infection, 14(12), 1044-1048 (2012-07-31)
Group B Streptococcus (GBS) is the leading cause of neonatal septicemia and meningitis. Pili appendages were shown to play a critical role in bacterial adhesion and colonization of human tissues. Recently it was claimed that binding of the pilus-associated adhesin
Gary Mok et al.
International journal of radiation oncology, biology, physics, 90(2), 278-288 (2014-10-12)
Dose-escalated radiation therapy for localized prostate cancer improves disease control but is also associated with worse rectal toxicity. A spacer placed between the prostate and rectum can be used to displace the anterior rectal wall outside of the high-dose radiation
Big bubble DALK after CXL in keratoconic patients.
Alfonso Iovieno et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 29(12), 801-801 (2013-12-07)
Panaghiotis Bazos et al.
The international journal of esthetic dentistry, 9(3), 330-352 (2014-08-16)
A thorough understanding of the spatial distribution pertaining to the histo-anatomic coronal structures and dynamic light interaction of the natural dentition provides the dental team with the ultimate strategic advantage with regards to optical integration of the final restoration. The
Jonathan G Sham et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(5), 799-804 (2014-03-15)
Hepatocellular carcinoma (HCC) is a devastating malignancy in which imperfect imaging plays a primary role in diagnosis. Glypican-3 (GPC3) is an HCC-specific cell surface proteoglycan overexpressed in most HCCs. This paper presents the use of (89)Zr-conjugated monoclonal antibody against GPC3
Débora Lopes Salles Scheffel et al.
American journal of dentistry, 27(6), 330-334 (2015-02-25)
To evaluate the influence of the time elapsed between the application and photoactivation of Single Bond 2 (SB) on microtensile bond strength (μTBS) and collagen exposure at the adhesive interface produced in the presence of intrapulp pressure. Dentin occlusal surfaces
Jiawang Gao et al.
PLoS pathogens, 19(1), e1011077-e1011077 (2023-01-19)
Ebola virus (EBOV) causes severe hemorrhagic fever in humans with high mortality. In Ebola virus disease (EVD) survivors, EBOV persistence in the eyes may break through the inner blood-retinal barrier (iBRB), leading to ocular complications and EVD recurrence. However, the
Self-organizing stem cells.
Natalie de Souza
Nature methods, 11(1), 31-31 (2014-02-14)
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