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Showing 1-30 of 257 results for "C7521" within Papers
Jillian L Astarita et al.
Nature immunology, 16(1), 75-84 (2014-10-28)
In lymph nodes, fibroblastic reticular cells (FRCs) form a collagen-based reticular network that supports migratory dendritic cells (DCs) and T cells and transports lymph. A hallmark of FRCs is their propensity to contract collagen, yet this function is poorly understood.
James E Dixon et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(15), 5580-5585 (2014-04-08)
The ability of materials to define the architecture and microenvironment experienced by cells provides new opportunities to direct the fate of human pluripotent stem cells (HPSCs) [Robinton DA, Daley GQ (2012) Nature 481(7381):295-305]. However, the conditions required for self-renewal vs.
Jonathan E Moore et al.
The British journal of ophthalmology, 98(2), 270-274 (2013-11-30)
Cross-linking of the cornea is usually carried out at a young age as a treatment to manage ectasia. The corneal limbal region contains delicate long-lived stem cells, which could potentially be deleteriously affected by Ultraviolet A (UV-A) radiation. Damage to
Yaowu Hu et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(1), 116-120 (2013-12-18)
Domestic cats are one of the most popular pets globally, but the process of their domestication is not well understood. Near Eastern wildcats are thought to have been attracted to food sources in early agricultural settlements, following a commensal pathway
Yuanming Ouyang et al.
Journal of biomedical nanotechnology, 9(6), 931-943 (2013-07-19)
An ideal nerve scaffold should supply structural guidance and trophic support to facilitate nerve regeneration. Aligned electrospun nanofibers have shown considerable promise for the precise guidance of regenerating axons in vitro and in vivo. Therefore, uniaxially aligned three-dimension (3D) nanofiberous
Sarah Finke et al.
Cell surface (Amsterdam, Netherlands), 5, 100032-100032 (2020-08-18)
Cyclic diguanylate (c-di-GMP) signalling affects several cellular processes in Bacillus cereus group bacteria including biofilm formation and motility, and CdgF was previously identified as a diguanylate cyclase promoting biofilm formation in B. thuringiensis. C-di-GMP can exert its function as a
Sriniwas Sriram et al.
Investigative ophthalmology & visual science, 54(13), 8214-8223 (2013-11-28)
Transforming growth factor β1 (TGFβ1), TGFβ receptor (TGFβR2), and connective tissue growth factor (CTGF) are key regulators of fibrosis in the cornea and in other tissues, including liver, skin, and kidney. We developed an antifibrotic treatment targeting these three critical
Hanne Haslene-Hox et al.
American journal of physiology. Heart and circulatory physiology, 308(1), H18-H28 (2014-11-09)
Elements of the extracellular matrix (ECM), notably collagen and glucosaminoglycans, will restrict part of the space available for soluble macromolecules simply because the molecules cannot occupy the same space. This phenomenon may influence macromolecular drug uptake. To study the influence
Zhen-Yu Hong et al.
Radiation research, 182(1), 83-91 (2014-06-18)
In a previous study, we established an image-guided small-animal micro-irradiation system mimicking clinical stereotactic body radiotherapy (SBRT). The goal of this study was to develop a rodent model of acute phase lung injury after ablative irradiation. A radiation dose of
JAK-STAT activation contributes to cytotoxic T cell-mediated basal cell death in human chronic lung allograft dysfunction.
Khatri, et al.
JCI insight, 8 (2023)
Ken Nakata et al.
Clinical calcium, 23(12), 1731-1739 (2013-12-03)
Meniscus is one of the most important tissues in knee joint from the biomechanical point of view. Meniscus injury is well known to cause osteoarthritis. At moment, there is a limitation of operative repair procedure especially for the meniscus injury
Jinfeng Zeng et al.
Small (Weinheim an der Bergstrasse, Germany), 16(24), e1907434-e1907434 (2020-05-07)
In recent decades, tissue engineering techniques have attracted much attention in the construction of 3D tissues or organs. However, even though precise control of cell locations in 3D has been achieved, the organized cell locations are easily destroyed because of
Catalina Carrasco-Pozo et al.
International journal of molecular sciences, 20(21) (2019-11-02)
Androgen receptor (AR) stimulators, such as androgen and Tip60, play a pivotal role in prostatic carcinogenesis as androgen receptor signaling is critical for the growth and transformation of the prostate gland. Moreover, androgen and Tip60 promotes HIF-1α activation, involved in
Eleanor Bates et al.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 6(5), 351-359 (2007-03-03)
Quinine has been increasingly utilized as a placebo in cystic fibrosis (CF) clinical trials, including those leading to FDA approval of inhaled tobramycin, recent studies of anti-inflammatory aerosols such as glutathione, and clinical testing of hypertonic saline aerosols to augment
PACK-CXL: defining CXL for infectious keratitis.
Farhad Hafezi et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 30(7), 438-439 (2014-07-02)
I Sanzari et al.
Scientific reports, 8(1), 11991-11991 (2018-08-12)
We recently demonstrated that patterned Parylene C films could be effectively used as a mask for directly copolymerizing proteins on polyacrylamide hydrogel (PAm). In this work, we have proved the applicability of this technique for studying the effect such platforms
Amy W Cheng et al.
The American surgeon, 80(10), 999-1002 (2014-09-30)
The use of biologic mesh in abdominal wall operations has gained popularity despite a paucity of outcome data. Numerous biologic products are available with virtually no clinical comparison studies. A retrospective study was conducted to compare patients who underwent abdominal
Xiaojing Li et al.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 72(2), 304-304 (2014-01-21)
The purpose of the present study was to compare a newly developed chitosan-collagen membrane (CCM) with a standard collagen membrane (SCM) regarding their effects on guided bone regeneration. The right mandibular premolars and first molar were extracted from 12 beagle
Jeroen Bastiaans et al.
Investigative ophthalmology & visual science, 54(13), 8306-8314 (2013-12-05)
De-differentiation of RPE cells into mesenchymal cells (epithelial-mesenchymal transition; EMT) and associated collagen production contributes to development of proliferative vitreoretinopathy (PVR). In patients with PVR, intraocular coagulation cascade activation occurs and may play an important initiating role. Therefore, we examined
Marco Rossi et al.
Investigative ophthalmology & visual science, 54(6), 4148-4157 (2013-05-25)
To evaluate the effect of corneal deswelling prior to a microkeratome and femtosecond (fs) laser cut and the impact of the fs laser energy settings on the tissue surface and collagen quality. Porcine and human corneas were incubated in THIN-C
Joanne B Tayapad et al.
Current opinion in ophthalmology, 24(4), 288-290 (2013-05-25)
This review presents current data regarding the use of collagen cross-linking in the management of corneal infections. Infectious keratitis can lead to blindness without proper antimicrobial therapy. The disease can still progress and lead to corneal melt despite early detection
Jon P Joelsson et al.
ALTEX, 36(4), 634-642 (2019-06-19)
Mechanical ventilation (MV) is a life-saving therapy for critically ill patients, alleviating the work of breathing and supporting adequate gas exchange. However, MV can cause ventilator induced lung injury (VILI) by baro/volu- and atelectrauma, even lead to acute respiratory distress
Geraldine M Jowett et al.
Nature materials, 20(2), 250-259 (2020-09-09)
Organoids can shed light on the dynamic interplay between complex tissues and rare cell types within a controlled microenvironment. Here, we develop gut organoid cocultures with type-1 innate lymphoid cells (ILC1) to dissect the impact of their accumulation in inflamed
Marta N Shahbazi et al.
Nature communications, 11(1), 3987-3987 (2020-08-12)
Aneuploidy, the presence of an abnormal number of chromosomes, is a major cause of early pregnancy loss in humans. Yet, the developmental consequences of specific aneuploidies remain unexplored. Here, we determine the extent of post-implantation development of human embryos bearing
Alejandro Arboleda et al.
Investigative ophthalmology & visual science, 55(4), 2731-2738 (2014-03-29)
To evaluate the efficacy of coulomb-controlled iontophoresis (CCI) for delivery of riboflavin prior to corneal collagen cross-linking (CXL). The eyes of 20 8-week-old Lewis rats, subject to epithelium-ON (epi-ON, n = 20 eyes) or epithelium-OFF (epi-OFF, n = 20 eyes)
Takeshi Imamura et al.
Clinical calcium, 23(12), 1767-1773 (2013-12-03)
Intravital optical imaging technique is a promising method that allows us to investigate complex vital phenomena in vivo . In particular, discovery and development of unique fluorescent proteins and smart fluorescent dyes in conjunction with appropriate equipment such as two-photon
Fillers and neocollagenesis.
Jean D A Carruthers et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 40 Suppl 12, S134-S136 (2014-11-25)
Characterization of a fold in TANGO1 evolved from SH3 domains for the export of bulky cargos.
Arnolds, et al.
Nature Communications, 14, 2273-2273 (2023)
Nienke Soeters et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 30(7), 454-460 (2014-06-04)
To compare the effect of corneal cross-linking (CXL) for keratoconus in various age groups and to investigate the influence of the topographic cone location on the outcome of CXL. This cohort study included 95 patients (119 eyes) diagnosed as having
Nancy L Sehgel et al.
Hypertension (Dallas, Tex. : 1979), 65(2), 370-377 (2014-12-03)
Hypertension and aging are both recognized to increase aortic stiffness, but their interactions are not completely understood. Most previous studies have attributed increased aortic stiffness to changes in extracellular matrix proteins that alter the mechanical properties of the vascular wall.
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