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Showing 1-30 of 31 results for "C8541" within Papers
Kai Josef Endriß et al.
Reproduction, fertility, and development, 33(4), 305-317 (2021-02-13)
In cattle, maternal recognition of early pregnancy depends on the effects of the embryonic signal interferon (IFN)-τ. IFN-stimulated genes have been upregulated in the maternal liver during early pregnancy. In this study, primary hepatocyte cell culture models were evaluated for
Anaïs Chauvin et al.
Methods in molecular biology (Clifton, N.J.), 1765, 155-166 (2018-03-29)
Proteomics allows the simultaneous detection and identification of thousands of proteins within a sample. Here, we describe a quantitative method to compare protein expression and subcellular localization of different cell lines representative of different stages of colorectal cancer using stable
Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain
Jiang Y, et al.
Experimental Hematology, 30(8), 896-904 (2002)
Role of extracellular signal-regulated kinase pathway in RRR-alpha-tocopheryl succinate-induced differentiation of human MDA-MB-435 breast cancer cells
You H, et al.
Molecular Carcinogenesis, 33(4), 228-236 (2002)
H Schlichenmaier et al.
Anatomia, histologia, embryologia, 31(5), 273-277 (2002-12-18)
The expression pattern of the intermediate filament protein cytokeratin 18 (CK 18) is described during pre- and post-natal development of the porcine lung using a monoclonal antibody against human CK 18. Lungs from 16 foetuses in pseudoglandular, canalicular, saccular and
Nikola Kolundzic et al.
Stem cell research, 38, 101462-101462 (2019-05-20)
We have generated an induced pluripotent stem cell (iPSC) line KCLi002-A (iOP107) from a female donor, heterozygous for the loss-of-function mutation p.R2447X in the filaggrin gene (FLG). Epidermal keratinocytes were reprogrammed using non-integrating Sendai virus vectors. The entire process of
Alex-Ane Mathieu et al.
Proteomics, 16(23), 3009-3018 (2016-10-01)
Studying cell differentiation and transformation allows a better understanding of the mechanisms involved in the initiation and the evolution of cancer. The role of proteins which participate in these processes is dependent on their location within the cell. Determining the
Le Ann Blomberg et al.
Molecular reproduction and development, 73(12), 1491-1502 (2006-08-12)
Gastrulation and trophectoderm elongation of the porcine conceptus coincide with peak conceptus estrogen secretion from gestational day 11 to day 12. The current study aim was to identify genes required for elongation by defining the transcriptome profile of this dynamic
Heather M Wilson et al.
Methods in molecular biology (Clifton, N.J.), 806, 187-201 (2011-11-08)
Culture of isolated kidney glomerular cells has been employed for almost four decades as a tool to dissect pathophysiological effects of individual cell types in renal disease. This chapter aims to highlight in detail the available techniques to isolate, culture
Fiona M Frame et al.
Methods in molecular biology (Clifton, N.J.), 1443, 181-201 (2016-06-02)
In order to fully explore the biology of a complex solid tumor such as prostate cancer, it is desirable to work with patient tissue. Only by working with cells from a tissue can we take into account patient variability and
Spatiotemporal analysis of putative notochordal cell markers reveals CD24 and keratins 8, 18, and 19 as notochord-specific markers during early human intervertebral disc developmen
Rodrigues-Pinto R, et al.
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society, 34(8), 1327-1340 (2016)
Characterization of new members of the human type II keratin gene family and a general evaluation of the keratin gene domain on chromosome 12q13.13
Rogers MA, et al.
The Journal of Investigative Dermatology, 124(3), 536-544 (2005)
J Ahenkorah et al.
Journal of cellular and molecular medicine, 13(4), 735-748 (2008-05-10)
We show here that at least 5 keratin proteins are present in villous trophoblast and the same 5 in extravillous trophoblast. A further 14 tested were undetectable in these tissues. In contrast, 10 of the 19 keratins tested were present
Nikola Kolundzic et al.
Stem cell research, 39, 101527-101527 (2019-08-14)
We have generated an induced pluripotent stem cell (iPSC) line KCLi003-A (iOP101) from epidermal keratinocytes of a female donor, heterozygous for the loss-of-function mutation p.R501X in the filaggrin gene (FLG), using non-integrating Sendai virus vectors. Derivation and expansion of iPSCs
Emer L Molloy et al.
Growth factors (Chur, Switzerland), 26(1), 12-22 (2008-03-28)
Bone morphogenetic proteins (BMPs) are critical morphogens and play key roles in epithelial-mesenchymal transitions (EMTs) during embryogenesis. BMP4 is required for early mesoderm formation and also regulates morphogenesis and epithelial cell differentiation in developing lungs. While, BMP signalling pathways are
Cinzia Cocola et al.
Journal of cellular biochemistry, 118(3), 570-584 (2016-09-16)
Recent studies suggest that human tumors are generated from cancer cells with stem cell (SC) properties. Spontaneously occurring cancers in dogs contain a diversity of cells that like for human tumors suggest that certain canine tumors are also generated from
H Inada et al.
The Journal of cell biology, 155(3), 415-426 (2001-10-31)
Keratin 8 and 18 (K8/18) are the major components of intermediate filament (IF) proteins of simple or single-layered epithelia. Recent data show that normal and malignant epithelial cells deficient in K8/18 are nearly 100 times more sensitive to tumor necrosis
Liani Devito et al.
Stem cell research, 31, 122-126 (2018-08-04)
We have generated an induced pluripotent stem cell (iPSC) line KCLi001-A (iOP118) from a female atopic dermatitis (AD) patient, heterozygous for the loss-of-function mutation c.2282del4 in the filaggrin gene (FLG). Epidermal keratinocytes were reprogrammed using non-integrating Sendai virus vectors. The
Immuno-electron microscopic localisation of caveolin 1 in human placenta
Byrne S, et al.
Immunobiology, 212(1), 39-46 (2007)
Matthew J Lawson et al.
Royal Society open science, 8(11), 211067-211067 (2021-11-06)
Micro-computed tomography (µCT) provides non-destructive three-dimensional (3D) imaging of soft tissue microstructures. Specific features in µCT images can be identified using correlated two-dimensional (2D) histology images allowing manual segmentation. However, this is very time-consuming and requires specialist knowledge of the
Thomas Brabletz et al.
Cancer research, 64(19), 6973-6977 (2004-10-07)
The homeobox transcription factor Cdx2 specifies intestinal development and homeostasis and is considered a tumor suppressor in colorectal carcinogenesis. However, Cdx2 mutations are rarely found. Invasion of colorectal cancer is characterized by a transient loss of differentiation and nuclear accumulation
Detection of PrPSc in rectal biopsy and necropsy samples from sheep with experimental scrapie
Espenes A, et al.
Journal of Comparative Pathology, 134(2-3), 115-125 (2006)
Carolyn J Baglole et al.
Methods in molecular medicine, 117, 115-127 (2005-08-25)
Primary fibroblasts represent a heterogeneous population of cells that can be separated into subsets on the basis of cell surface markers such as Thy-1. Deriving fibroblasts initially involves obtaining tissue explants from tissues such as the lung, heart, cornea, skin
Alexia Nunez-Parra et al.
Chemical senses, 36(9), 771-780 (2011-06-17)
Cell-to-cell metabolic interactions are crucial for the functioning of the nervous system and depend on the differential expression of glucose transporters (GLUTs) and monocarboxylate transporters (MCTs). The olfactory receptor neurons (ORNs) and supporting cells (SCs) of the olfactory epithelium exhibit
Nobuyuki Nishikawa et al.
Endocrinology, 154(6), 2058-2068 (2013-04-03)
Acute bladder distension causes various morphologic and functional changes, in part through altered gene expression. We aimed to investigate the physiologic role of PTHrP, which is up-regulated in an acute bladder distension model in female rats. In the control Empty
Poonam S Kakade et al.
The Journal of biological chemistry, 291(23), 12003-12013 (2016-04-10)
Keratins 8/18 (K8/18) are phosphoglycoproteins and form the major intermediate filament network of simple epithelia. The three O-GlcNAcylation (Ser(29), Ser(30), and Ser(48)) and two phosphorylation (Ser(33) and Ser(52)) serine sites on K18 are well characterized. Both of these modifications have
Khalidah Ibraheem et al.
Cells, 11(20) (2022-10-28)
The capacity to induce tumour-cell specific apoptosis represents the most unique feature of the TNF receptor (TNFR) family member CD40. Recent studies on the signalling events triggered by its membrane-presented ligand CD40L (mCD40L) in normal and malignant epithelial cells have
Cytokeratin 18 knockdown decreases cell migration and increases chemosensitivity in non-small cell lung cancer
Zhang B, et al.
Journal of Cancer Research and Clinical Oncology, 142(12), 2479-2487 (2016)
Increased plasma levels of CK-18 as potential cell death biomarker in patients with HELLP syndrome
John K, et al.
Cell Death & Disease, 4(10), e886-e886 (2013)
Sirpa Aho
Experimental dermatology, 13(11), 700-707 (2004-10-27)
In epithelial cells, cell-cell and cell-matrix junctions, desmosomes and hemidesmosomes, provide anchorage sites for the keratin-intermediate filaments. The plakin proteins desmoplakin (DP), plectin, and periplakin represent intracellular constituents of these adhesion junctions. In staurosporine-treated apoptotic HaCaT cells, DP, plectin, and
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