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Showing 1-30 of 33 results for "C9080" within Papers
Jule K Michler et al.
Cytometry. Part A : the journal of the International Society for Analytical Cytology, 93(1), 104-114 (2017-09-03)
The easily accessible niche represented by skin and its appendages may serve as a promising source to complement modern regenerative medicine for horses. In humans and in animal models for human medicine, the hair follicle and its stem cell niches
Richard A Lasher et al.
Journal of tissue engineering, 3(1), 2041731412455354-2041731412455354 (2012-08-25)
Quantifying structural features of native myocardium in engineered tissue is essential for creating functional tissue that can serve as a surrogate for in vitro testing or the eventual replacement of diseased or injured myocardium. We applied three-dimensional confocal imaging and
Guangheng Li et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 20(9), 1611-1623 (2005-08-02)
After intramuscular implantation, BMP4-expressing NIH/3T3 fibroblasts and BMP4-expressing C2C12 myoblasts can promote ectopic cartilage and bone formation. Fibroblasts tend to undergo chondrogenesis, whereas myoblasts primarily undergo osteogenesis. These results suggest that endochondral bone formation may involve different cell types, a
Arun Satelli et al.
Cellular and molecular life sciences : CMLS, 68(18), 3033-3046 (2011-06-04)
Vimentin, a major constituent of the intermediate filament family of proteins, is ubiquitously expressed in normal mesenchymal cells and is known to maintain cellular integrity and provide resistance against stress. Vimentin is overexpressed in various epithelial cancers, including prostate cancer
Ze-Wei Tao et al.
Acta biomaterialia, 101, 206-218 (2019-10-28)
Congenital heart defects affect about 1% births in the United States. Many of the defects are treated with surgically implanted patches made from inactive materials or fixed pericardium that do not grow with the patients, leading to an increased risk
Dennis Webster et al.
Frontiers in genetics, 11, 627673-627673 (2021-02-16)
To study the pathophysiology of human diseases, develop innovative treatments, and refine approaches for regenerative medicine require appropriate preclinical models. Pigs share physiologic and anatomic characteristics with humans and are genetically more similar to humans than are mice. Genetically modified
Lilian Gonçalves dos Reis Bastos et al.
Journal of cellular biochemistry, 115(12), 2175-2187 (2014-08-12)
Radiotherapy remains a major approach to adjuvant therapy for patients with advanced colorectal cancer, however, the fractionation schedules frequently allow for the repopulation of surviving tumors cells, neoplastic progression, and subsequent metastasis. The aim of the present study was to
Pauliina Filppu et al.
JCI insight, 6(9) (2021-05-15)
Glioma stem cells (GSCs) drive propagation and therapeutic resistance of glioblastomas, the most aggressive diffuse brain tumors. However, the molecular mechanisms that maintain the stemness and promote therapy resistance remain poorly understood. Here we report CD109/STAT3 axis as crucial for
Marina Yasvoina et al.
The British journal of ophthalmology (2022-03-19)
Invasion of pigmented cells into the retina occurs in retinal degenerative diseases, such as macular telangiectasia type 2 (MacTel) and retinitis pigmentosa (RP). These intraretinal pigmented cells may be derived from the retinal pigment epithelium (RPE), but differences and similarities
Coexpression of keratin-and vimentin-type intermediate filaments in human metastatic carcinoma cells
Ramaekers FC, et al.
Proceedings of the National Academy of Sciences of the USA, 80(9), 2618-2622 (1983)
Michael B Powner et al.
Ophthalmology, 120(11), 2344-2352 (2013-06-19)
To correlate postmortem histology from a patient with macular telangiectasia (MacTel) type 2 with previously recorded clinical imaging data. Observational clinicopathologic case report. The distribution of retinal blood vessels was used to map the location of serial wax sections in
Sandra Noriega et al.
Cells, tissues, organs, 197(1), 14-26 (2012-09-19)
The impact of low-intensity diffuse ultrasound (LIDUS) stimulation on the cytoskeletal organization of chondrocytes seeded in three-dimensional (3D) scaffolds was evaluated. Chondrocytes seeded on 3D chitosan matrices were exposed to LIDUS at 5.0 MHz (approx. 15 kPa, 51 s, 4
Yimu Zhao et al.
Matrix biology : journal of the International Society for Matrix Biology, 85-86, 189-204 (2019-04-15)
Organ-on-a-chip systems have the potential to revolutionize drug screening and disease modeling through the use of human stem cell-derived cardiomyocytes. The predictive power of these tissue models critically depends on the functional assembly and maturation of human cells that are
Prakash Chelladurai et al.
Scientific reports, 10(1), 12864-12864 (2020-08-01)
Pharmacological modulation of class I histone deacetylases (HDAC) has been evaluated as a therapeutic strategy for pulmonary hypertension (PH) in experimental models of PH. However, information of their expression, regulation and transcriptional targets in human PH and the therapeutic potential
Phenotypical and ultrastructural features of Oct4-positive cells in the adult mouse lung
Galiger C, et al.
Journal of Cellular and Molecular Medicine, 18(7), 1321-1333 (2014)
Michael B Powner et al.
Investigative ophthalmology & visual science, 57(11), 5031-5037 (2016-09-24)
Retinal ischemia has been traditionally assessed by fluorescein angiography, visualizing perfused vessels. However, this method does not provide any information about nonperfused vessels, and although it is often assumed that vessels in ischemic areas regress, we know little about how
Izabela Nita et al.
Scientific reports, 7, 41901-41901 (2017-02-06)
Idiopathic Pulmonary Fibrosis (IPF) is a progressive, irreversible lung disease with complex pathophysiology. Evidence of endoplasmic reticulum (ER) stress has been reported in alveolar epithelial cells (AEC) in IPF patients. Secreted mediators from bone marrow stem cells (BMSC-cm) have regenerative
Dillon K Jarrell et al.
PloS one, 16(5), e0239242-e0239242 (2021-05-20)
Fibrin has been used clinically for wound coverings, surgical glues, and cell delivery because of its affordability, cytocompatibility, and ability to modulate angiogenesis and inflammation. However, its rapid degradation rate has limited its usefulness as a scaffold for 3D cell
Nidheesh Dadheech et al.
Stem cell research & therapy, 11(1), 327-327 (2020-08-01)
Despite the potential, bone marrow-derived mesenchymal stem cells (BMSCs) show limitations for beta (ß)-cell replacement therapy due to inefficient methods to deliver BMSCs into pancreatic lineage. In this study, we report TGF-ß family member protein, Activin-a potential to stimulate efficient
Sven Otto et al.
PloS one, 16(5), e0251530-e0251530 (2021-05-21)
Distal axonopathy is seen in a broad range of species including equine patients. In horses, this degenerative disorder of the recurrent laryngeal nerve is described as recurrent laryngeal neuropathy (RLN). The dysfunctional innervation of the cricoarytenoideus dorsalis muscle (CAD) leads
Michael B Powner et al.
Retina (Philadelphia, Pa.), 38 Suppl 1, S105-S113 (2017-10-19)
Macular telangiectasia Type 2 (MacTel) causes glial and photoreceptor cell death in a small, oval patch in the central retina. Beyond this oval area, no disease manifestations have been described so far. Here, we describe a novel pathological aspect of
Morphology of the myoepithelial cell: immunohistochemical characterization from resting to motile phase
Beha G, et al.
TheScientificWorldJournal, 2012 (2012)
HaYeun Ji et al.
Biomaterials, 85, 180-194 (2016-02-14)
Access to smooth muscle cells (SMC) would create opportunities for tissue engineering, drug testing, and disease modeling. Herein we report the direct conversion of human endothelial progenitor cells (EPC) to induced smooth muscle cells (iSMC) by induced expression of MYOCD.
Munehiro Yuhki et al.
Reproductive biology and endocrinology : RB&E, 9, 104-104 (2011-08-02)
Studies on the mechanisms of decidualization and endometriosis are often hampered by lack of primary endometrial cells. To facilitate in vitro studies, we established a human endometrial stromal cell line, KC02-44D, immortalized with human telomerase reverse transcriptase. Upon exposure to
Loraine L Y Chiu et al.
Tissue engineering. Part A, 17(11-12), 1465-1477 (2008-09-12)
The main objectives of current work were (1) to compare the effects of monophasic or biphasic electrical field stimulation on structure and function of engineered cardiac organoids based on enriched cardiomyocytes (CM) and (2) to determine if electrical field stimulation
Intermediate filaments of the vimentin and prekeratin type in human epidermis
Mahrle G, et al.
The Journal of Investigative Dermatology, 81(1), 46-48 (1983)
C Dores et al.
Andrology, 3(3), 590-597 (2015-04-17)
To study spermatogonial stem cells the heterogeneous testicular cell population first needs to be enriched for undifferentiated spermatogonia, which contain the stem cell population. When working with non-rodent models, this step requires working with large numbers of cells. Available cell
Basic fibroblast growth factor controls migration in human mesenchymal stem cells
Schmidt A, et al.
Stem Cells, 24(7), 1750-1758 (2006)
Selwa Mokhtar Boularaoui et al.
Journal of tissue engineering and regenerative medicine, 12(2), e918-e936 (2017-01-20)
Skeletal muscle holds significant regenerative potential but is incapable of restoring tissue loss caused by severe injury, congenital defects or tumour ablation. Consequently, skeletal muscle models are being developed to study human pathophysiology and regeneration. Their physiological accuracy, however, is
Juan Vélez et al.
Biology, 10(10) (2021-10-24)
The apicomplexan Cryptosporidium parvum causes thousands of human deaths yearly. Since bovines represent the most important reservoir of C. parvum, the analysis of infected bovine small intestinal (BSI) explants cultured under physioxia offers a realistic model to study C. parvum-host
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