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cd45
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Showing 1-30 of 62 results for "cd45" within Technical Documents
MOUSE ANTI-HUMAN CD45
the
Western blotting technique
Studies of CD45 expression and the association with T-cell receptor signaling
Studies of the mechanism by which CD45 regulates B cell activation through protein tyrosine
Monoclonal Anti-Human CD45 Biotin Conjugate Purified Mouse Immunoglobulin Clone Bra-55
preservative.
Description
Monoclonal anti-human CD45 antibody recognizes the
CD45 human cell surface glycoproteins of 180, 190, 205
and 220 kD. CD45 is a family of single chain,
transmembraneous glycoproteins
Data Sheet - C7556
immunological
functions.
Monoclonal Anti-Human CD45 antibody recognizes the
CD45 human cell surface glycoproteins 180, 190, 205,
and 220 kDa. CD45 is a family of single chain trans-
membraneous glycoproteins
Data Sheet - P7687
handling practices.
Description
Monoclonal Anti-CD45 antibody recognizes the CD45
human cell surface glycoproteins 180, 190, 205 and
220 kDa. CD45 is a family of single chain
transmembraneous glycoproteins
Data Sheet - F8527
antibody is detectable.
Monoclonal Anti-Human CD45 antibody recognizes the
CD45 human cell surface glycoprotein of 180, 190, 205,
and 220 kDa. CD45 is a family of single chain
transmembrane glycoproteins
Data Sheet - F4149
purified CD45 monoclonal antibody. The
conjugate is then purified by gel filtration to remove
unbound FITC. No free FITC is detectable.
Monoclonal Anti-Human CD45 antibody recognizes the
CD45 human
FlowCellect™ Human B-cell FAS Kit (100 Tests)
anti-human CD45 antibody (clone 2D1)
recognizes CD45, a single chain type I transmembrane protein typically is expressed at high levels on
nucleated cells of haematopoietic origin (1). CD45 is present
Data Sheet - F7792
when gating on CD45
positive cells.
Uses
This product is intended for use as the negative isotype
control for TRI-TAG reagents of the mouse IgG1-FITC/
mouse IgG2a-PE/anti-human CD45-Quantum Red format
Data Sheet - F7900
F7900\ANYLOT.DAT
MONOCLONAL ANTI-MOUSE CD45
FITC CONJUGATE CLONE I3/2
Purified Rat Immunoglobulin
Product No. F7900
Monoclonal Anti-Mouse CD45 (rat IgG2a isotype) is conjunction with R-PE
Mesenchymal Stem Cell Characterization Kit (Rat)
selection
antibodies. In addition, antibodies to CD14 and CD45 are two negative selection
markers that are provided with the kit. CD14 and CD45 are two surface markers
that are present on leukocytes and
Data Sheet - D8065
competitive with the substrate.
Dephostatin inhibits CD45, a T-cell receptor-associated
transmembrane PTPase found on nucleated
hematopoietic cells. CD45, leukocyte common antigen-
related PTPase, as well
Growth Kinetics of Human Mesenchymal Stem Cells in the Mobius® Single-use Bioreactor
establishing the
cells in the lab, hMSCs were characterized by flow cytometry. CD90+, CD105+, CD73+, CD34-, CD45-, CD11b-
cell surface antigen profiles were expressed as expected (guidance from Dominici, et al.
Rat Mesenchymal Stem Cell Kit
directed against two specific hematopoietic cell surface
markers, (CD14, present on leukocytes and CD45, present on monocytes and
macrophages) that are not expressed by mesenchymal stem cells (2, 3, 4)
Data Sheet - G7420
activities of galectin-1 include cell differentiation
and inhibition of CD45 protein phosphatase activity.
Galectin-1 binds CD45, CD3, and CD4 in addition to
-galactoside. Galectin-1 bound in the
Data Sheet - SRP5079
Catalog Number SRP5079
Storage Temperature –70 °C
Synonyms: B220, Cd45, CD45R, loc, Ly-5, Lyt-4, T200
Product Description
PTPRC (CD45) contains an extracellular domain, a
single transmembrane segment
Rat Mesenchymal Stem Cell Kit
directed against two specific hematopoietic cell surface
markers, (CD14, present on leukocytes and CD45, present on monocytes and
macrophages) that are not expressed by mesenchymal stem cells (2, 3, 4)
Data Sheet - F8025
Description
FITC Conjugated Monoclonal Anti-Mouse CD45R
recognizes the 220 kD isoform (B220) of CD45 ex-
pressed on pre-B cells and B cells. Other isoforms are
a 200 kD antigen expressed on all leukocytes
Protein Phosphatases Technical Bulletin
217614 Corresponds to the cytoplasmic domain (amino acid residues 584 – 1281) of 20 mg
CD45, Human, Recombinant human CD45. Useful for regulation and inhibition studies. M.W. 95 kDa.
Activity: ≥20,000 units
CCMCL1 Mantle Cell Lymphoma Cell Line
analysis of cell surface
molecules. CCMCL1 cells express high levels of CD19 (B),
CD20 (C) and CD45 (D) and are negative for CD3 (E) and
CD25 (F).
CCMCL1 Mantle Cell Lymphoma
Cell Line
Product Information Sheet - PTP101
.4
1.6
1.8
2
LAR T-cell
PTPase
CD45
A
62
0
Protein tyrosine phosphatases, LAR PTP, 1U (Sigma
L0907), T-cell PTP, 1U (Calbiochem ) and CD45, 1U
(Calbiochem) were incubated for 10 min
Improved Ex Vivo Expansion of Functional CD34plus Cells Using Stemline II Hematopoietic Stem Cell Expansion Medium
.064 ± 0.017 ± 0.143 ± 0.036 ± 0.018 ± 0.108 ±
CD45+ 0.061 0.006 0.081 0.013 0.019 0.162
Average % 0.000 ± 0.003 ± 0.007 ± 0.011 ± 0.002 ± 0.010 ±
CD45+/CD34+ 0.000 0.006 0.006 0.009 0.004 0.000
Optimal Serum-Free Ex Vivo Expansion and Activation of T Lymphocytes Using Stemline T CellExpansion Medium
Figure 3A. Engraftment of human T cells in the NOD/SCID-β2M mouse spleen
(200x mag, anti-human CD45 - Red).
0%
10%
20%
30%
40%
–10%
%
K
56
2
ly
si
s
Data Sheet - M1941
with ATP. This
autophosphorylation and activation is reversed by
protein phosphatase 2A2, but not by CD45 or protein
tyrosine phosphatase.1
The MAPK family of kinases is activated as a rapid
intracellular
Data Sheet
an estimated 36 hour doubling time. SCCOHT-1
cells are positive for CD29 and negative for CD24 and CD45 as assessed by flow cytometry. Injection of distinct
subpopulations of the SCCOHT-1 cell line exhibited
Data Sheet - GW21465
at –20 °C
Synonyms: Protein tyrosine phosphatase, receptor type, C
isoform 1, EC 3.1.3.48; L-CA; CD45 antigen; T200
Product Description
Required for T-cell activation through the antigen receptor.
Data Sheet-SCC437
an estimated 36 hour doubling time. SCCOHT-1
cells are positive for CD29 and negative for CD24 and CD45 as assessed by flow cytometry. Injection of distinct
subpopulations of the SCCOHT-1 cell line exhibited
Data Sheet - M9440
dephostatin were
synthesized.3 However, only methyl-3,4-dephostatin
inhibits the PTPase activity of CD45. This analogue is
10 times more stable than dephostatin in cell culture
media.3 It strongly inhibits
Data Sheet - E1904
receptor 3 substrate (IRS-3). However, unlike
dephostatin, this analog did not effectively inhibit
CD45-associated PTPase.2
Preparation Instructions
Ethyl-3,4-dephostatin is soluble in DMSO at 22 mg
Data Sheet - P0857
receptor
transmembrane-type PTPs and non-receptor,
intracellular PTPs. The receptor PTPs (e.g. LAR, CD45,
PTP α, β, δ, µ, κ, etc.) contain a general structure of
membrane receptor with an extracellular domain
Data Sheet - P8998
phosphatases inhibit
activities of phosphorylation cascades, some activate
them. The tyrosine phosphatase CD45, for example,
activates the Src family tyrosine kinases by
dephosphorylating an inhibitory phosphotyrosine
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