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Showing 1-30 of 715 results for "cd90" within Papers
Kiyoko Kawamura et al.
American journal of clinical pathology, 140(4), 544-549 (2013-09-21)
To pathologically distinguish mesothelioma from lung carcinoma, particularly adenocarcinoma. We conducted immunohistochemical analyses on clinical specimens, including 26 cases of mesothelioma, 28 cases of lung adenocarcinoma, and 33 cases of lung squamous cell carcinoma. We found that CD90 expression was
Xi Zhang et al.
Journal of experimental & clinical cancer research : CR, 35(1), 176-176 (2016-11-12)
Cancer stem cells (CSCs) are important in the tumorigenesis and progression of hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) play crucial roles regulating CD133 The miRNA profiles of CD90 miR-589-5p and miR-33b-5p were down-regulated in CD90 In HCC, miR-589-5p down-regulates the stemness
Ke Cheng et al.
Journal of the American Heart Association, 3(5), e001260-e001260 (2014-10-11)
The regenerative potential of cardiosphere-derived cells (CDCs) for ischemic heart disease has been demonstrated in mice, rats, pigs, and a recently completed clinical trial (CADUCEUS). CDCs are CD105(+) stromal cells of intrinsic cardiac origin, but the antigenic characteristics of the
Limei Wang et al.
American journal of physiology. Lung cellular and molecular physiology, 318(4), L813-L830 (2020-02-20)
Our understanding of mesenchymal cell subsets and their function in human lung affected by aging and in certain disease settings remains poorly described. We use a combination of flow cytometry, prospective cell-sorting strategies, confocal imaging, and modeling of microvessel formation
Bo Fu et al.
Cytotechnology, 72(3), 433-444 (2020-03-15)
Although nonwoven fabric (NWF) has been reported to be a candidate scaffold for the large-scale expansion of mesenchymal stem cells (MSCs), the quality of cells grown in NWF has not been well clarified. In this report, MSCs grown in an
Luo Chen et al.
Cancers, 15(7) (2023-04-14)
We had previously shown that THY1 (CD90) is a tumor suppressor in nasopharyngeal carcinoma (NPC) and that its down-regulation and loss of expression are associated with tumor metastasis, yet the mechanism leading to such effects remains unknown. In this study
Olga N Karpus et al.
Cell reports, 26(13), 3698-3708 (2019-03-28)
Intestinal epithelial cells have a defined hierarchy with stem cells located at the bottom of the crypt and differentiated cells more at the top. Epithelial cell renewal and differentiation are strictly controlled by various regulatory signals provided by epithelial as
Elmar Kirches et al.
Journal of neuro-oncology, 138(2), 251-259 (2018-02-23)
Mesenchymal stem cells (MSC) have been found in various cancers and were discussed to influence tumor biology. Cells fulfilling the complete MSC criteria, including surface marker expression (CD73, CD90, CD105) and tri-lineage differentiation, have been isolated solely from a low
Yuanlong Li et al.
Journal of nanobiotechnology, 20(1), 150-150 (2022-03-21)
Osteoarthritis (OA) is a highly prevalent human degenerative joint disorder that has long plagued patients. Glucocorticoid injection into the intra-articular (IA) cavity provides potential short-term analgesia and anti-inflammatory effects, but long-term IA injections cause loss of cartilage. Synovial mesenchymal stem
You-Kyoung Kim et al.
Stem cells translational medicine, 5(2), 227-234 (2016-01-01)
The treatment of bone defects still presents complex problems, although various techniques have been developed. The periosteum is considered a good source of osteogenic precursor cells for new bone formation. It can be collected easily in the clinical setting and
Xueliang Wang et al.
International journal of clinical and experimental pathology, 8(5), 5105-5112 (2015-07-21)
The epithelial-mesenchymal transition (EMT) generates cells with properties of stem cells, if that happened, the stem cell should be with mesenchymal property. This study aimed to identify a group of cells with mesenchymal stem cell (MSC)-like characteristics in breast cancer
Yang Zeng et al.
Oncotarget, 10(43), 4479-4491 (2019-07-20)
Both anti-tumoral and pro-tumoral effects of mesenchymal stem cells (MSCs) in preclinical treatment of ovarian cancer have been controversially demonstrated. In this study, we profiled the phenotypes of mouse compact bone-derived MSCs (CB-MSCs) and bone marrow-derived MSCs (BM-MSCs) and found
Collynn F Woeller et al.
Toxicological sciences : an official journal of the Society of Toxicology, 157(2), 305-319 (2017-03-23)
Environmental chemicals termed "obesogens" disrupt the endocrine system to promote adipogenesis and obesity. Tetrabromobisphenol-A (TBBPA) has been reported to increase adipogenesis; however, the mechanism(s) of action are unclear. Thy1 (CD90) is a glycophosphatidylinositol-anchored membrane protein that serves as a marker
Lichao Sun et al.
Journal of Cancer, 8(1), 111-116 (2017-01-27)
The development of liver cancer would undergo a sequential progression from chronic inflammatory liver disease, cirrhosis to neoplasia. During these pathophysiological changes, abnormal liver microenvironment might induce the hepatocytes to die, abnormally proliferate and initiate cancer stem cells. Metallocarboxypeptidases (MCPs)
Liang Wu et al.
Annals of translational medicine, 9(4), 282-282 (2021-03-13)
Diabetic kidney disease (DKD), the major cause of chronic kidney disease, is associated with progressive renal fibrosis. The expression of CD90 correlated with fibrogenesis. However, the association between urinary soluble CD90 and renal disease severity, and whether it predicts outcomes
Hongyu Wang et al.
Biochimie, 181, 25-33 (2020-11-27)
Modified DNA aptamers incorporated with amino-acid like side chains or drug-like ligands can offer unique advantages and enhance specificity as affinity ligands. Thy-1 membrane glycoprotein (THY1 or CD90) was previously identified as a biomarker candidate of neovasculature in pancreatic ductal
Yanzhen Li et al.
Biomaterials, 236, 119824-119824 (2020-02-07)
In response to heart injury, inflammation, or mechanical overload, quiescent cardiac fibroblasts (CFs) can become activated myofibroblasts leading to pathological matrix remodeling and decline in cardiac function. Specific targeting of fibroblasts may thus enable new therapeutic strategies to delay or
Megan E Dempsey et al.
Cellular and molecular bioengineering, 14(3), 267-277 (2021-06-11)
Antibodies are an essential research tool for labeling surface proteins but can potentially influence the behavior of proteins and cells to which they bind. Because of this, researchers and clinicians are interested in the persistence of these antibodies, particularly for
Shuyu Liu et al.
Ecotoxicology and environmental safety, 169, 564-572 (2018-11-27)
PFOS and PFOA are two of the most abundant perfluorinated compounds (PFCs) in the environment. Previous studies have reported they have a long half-life (up to five years) once they enter into the human body. Moreover, they can potentially promote
Kotaro Horiguchi et al.
Biochemical and biophysical research communications, 480(2), 273-279 (2016-10-30)
Contact-dependent (juxtacrine) signaling is important for local cell-to-cell interaction and has received attention in recent years regarding its role in pituitary function, differentiation, and development. This study investigated one of the juxtacrine-related molecules, thymocyte differentiation antigen 1 (THY1), in the
Vera S Donnenberg et al.
Cytometry. Part A : the journal of the International Society for Analytical Cytology, 93(4), 448-457 (2018-03-03)
Flow cytometric cell surface proteomics provides a new and powerful tool to determine changes accompanying neoplastic transformation and invasion, providing clues to essential interactions with the microenvironment as well as leads for potential therapeutic targets. One of the most important
CD90.
A J Henniker
Journal of biological regulators and homeostatic agents, 15(4), 392-393 (2002-02-28)
CD90.
A Zucchini et al.
Journal of biological regulators and homeostatic agents, 15(1), 82-85 (2001-06-05)
Zhen Fan Yang et al.
Cancer cell, 13(2), 153-166 (2008-02-05)
This study characterized cancer stem cells (CSCs) in hepatocellular carcinoma (HCC) cell lines, tumor specimens, and blood samples. The CD90+ cells, but not the CD90(-) cells, from HCC cell lines displayed tumorigenic capacity. All the tumor specimens and 91.6% of
Zhen Fan Yang et al.
Cancer cell, 13(2), 153-166 (2008-02-05)
This study characterized cancer stem cells (CSCs) in hepatocellular carcinoma (HCC) cell lines, tumor specimens, and blood samples. The CD90+ cells, but not the CD90(-) cells, from HCC cell lines displayed tumorigenic capacity. All the tumor specimens and 91.6% of
Florian Kollert et al.
Arthritis care & research, 65(2), 281-287 (2012-07-19)
Vascular injury and endothelial cell (EC) activation are pathogenic hallmarks of systemic sclerosis (SSc; scleroderma). Human CD90 is highly expressed on activated ECs and can be shed from the cell surface. This study was conducted to examine whether soluble CD90
Kazuhiko Oishi et al.
Biochemical and biophysical research communications, 349(3), 1065-1072 (2006-09-12)
Although it is now clear that several subpopulations of neural stem cells (NSCs) exist during early development and adulthood, the angiogenic potential of NSCs remains a subject of debate. Here, we report that CD44(+) CD90(+) cells isolated from primary neurospheres
Kathleen Schubert et al.
European journal of immunology, 41(3), 645-656 (2011-01-26)
Human Thy-1 (CD90) has been shown to mediate adhesion of inflammatory cells to activated microvascular endothelial cells via interaction with Mac-1 (CD11b/CD18) in vitro. Since there are no data showing the physiological relevance of Thy-1 for the recruitment of inflammatory
Henning C Fiegel et al.
Pediatric surgery international, 24(1), 101-105 (2007-10-24)
Neuroblastoma (NBL) is the most common solid tumor in children. Tumors in advanced stage or with positive risk factors still have a poor prognosis. Thy1 (CD90) is a membrane glycoprotein expressed in thymus, retinal ganglionic cells, and several types of
Elke Wandel et al.
Journal of immunology (Baltimore, Md. : 1950), 188(3), 1442-1450 (2012-01-03)
Leukocyte recruitment in response to inflammatory signals is governed, in part, by binding to Thy-1 (CD90) on activated endothelial cells (EC). In this study, we characterized the adhesion G-protein coupled receptor CD97, present on peripheral myeloid cells, as a novel
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