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Showing 1-7 of 7 results for "CLS431750" within Papers
Jiaxing Li et al.
Frontiers in cell and developmental biology, 9, 598364-598364 (2021-02-16)
Decidualization is driven by differentiation of human endometrial stromal cells (ESCs), and is a prerequisite for successful implantation and establishment of pregnancy. The critical role of impaired decidualization in women suffered recurrent implantation failure (RIF) has been established, while the
Xiao Huang et al.
Nature nanotechnology, 16(2), 214-223 (2020-12-16)
Biomaterials can improve the safety and presentation of therapeutic agents for effective immunotherapy, and a high level of control over surface functionalization is essential for immune cell modulation. Here, we developed biocompatible immune cell-engaging particles (ICEp) that use synthetic short
Daniel Ley et al.
Metabolic engineering, 56, 120-129 (2019-09-19)
Chinese hamster ovary (CHO) cells are the preferred host for producing biopharmaceuticals. Amino acids are biologically important precursors for CHO metabolism; they serve as building blocks for proteogenesis, including synthesis of biomass and recombinant proteins, and are utilized for growth
Ziqiang Wang et al.
Cellular and molecular life sciences : CMLS, 77(17), 3441-3452 (2019-12-16)
The elevated expression of immune checkpoints by the tumor microenvironment is associated with poor prognosis in several cancers due to the exhaustion of tumor-infiltrating lymphocytes (TILs), and the effective suppression of the expression of these genes is key to reversing
Seetharam Deepa et al.
Theriogenology, 161, 161-175 (2020-12-18)
Wnt signaling is conserved among all species and plays a significant role in various cellular processes including reproduction. The present study identified significant involvement of wnt4a, wnt5b, and wnt8a signaling in the testicular growth of common carp,Cyprinus carpio. Predominant expression
Joseph Park et al.
Nature medicine, 27(1), 66-72 (2021-01-13)
The clinical impact of rare loss-of-function variants has yet to be determined for most genes. Integration of DNA sequencing data with electronic health records (EHRs) could enhance our understanding of the contribution of rare genetic variation to human disease1. By
Joanna Kalucka et al.
Cell, 180(4), 764-779 (2020-02-16)
The heterogeneity of endothelial cells (ECs) across tissues remains incompletely inventoried. We constructed an atlas of >32,000 single-EC transcriptomes from 11 mouse tissues and identified 78 EC subclusters, including Aqp7+ intestinal capillaries and angiogenic ECs in healthy tissues. ECs from
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