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Showing 1-30 of 147 results for "D1133" within Papers
P C Adams et al.
Hepatology (Baltimore, Md.), 14(6), 1230-1234 (1991-12-01)
The elimination of toxic metal ions metabolically accumulated by patients remains a difficult clinical problem and a target of drug development. DTPA (diethylenetriaminepentaacetic acid) is a hydrophilic chelating agent with high affinity for divalent and trivalent metal ions including iron
Manish Garg et al.
Urology, 83(4), 805-811 (2014-02-04)
To determine the subjective and objective outcomes of retroperitoneoscopic vs open pyeloplasty with minimal incision in a prospective randomized comparison study. In this study between August 2011 to July 2013, 30 patients underwent retroperitoneal laparoscopic pyeloplasty and 30 open pyeloplasty
Ali Rabie et al.
Annals of nuclear medicine, 29(10), 870-876 (2015-08-12)
Various phosphonate ligands labeled with β(-)-emitting radionuclides have shown good efficacy for bone pain palliation. In this study, a new agent for bone pain palliation has been developed. ¹⁵³Sm-(4-{[(bis(phosphonomethyl))carbamoyl]methyl}-7,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl) acetic acid (¹⁵³Sm-BPAMD) complex was prepared using BPAMD ligand and ¹⁵³SmCl3.
Matthias Fellner et al.
Analytical biochemistry, 459, 56-60 (2014-05-27)
A fast and easy method for enzyme activity assays using the chromogenic Ellman reagent, 5,5'-dithiobis(2-nitrobenzoic acid), was developed. The method was used to measure the activity of the nonheme mono-iron enzyme cysteine dioxygenase. Quantifying the depletion of the substrate, cysteine
Ken-ichiro Matsumoto et al.
Chemical & pharmaceutical bulletin, 63(3), 195-199 (2015-03-12)
The density of hydroxyl radicals (·OH) produced in aqueous samples by exposure to X-ray or carbon-ion beams was investigated. The generation of ·OH was detected by the electron paramagnetic resonance (EPR) spin-trapping technique using 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) as the spin-trapping agent.
Fabian aus dem Siepen et al.
Clinical research in cardiology : official journal of the German Cardiac Society, 104(8), 640-647 (2015-04-10)
T1 mapping by cardiac magnetic resonance imaging (CMR) is able to determine the extracellular volume fraction. Wild-type transthyretin amyloidosis (WT-ATTR) is characterized by extracellular amyloid deposition in the heart. Recent reports indicated a reduction of left ventricular (LV) myocardial mass
P C Braga et al.
Drug research, 65(5), 244-251 (2014-06-12)
A new diclofenac salt called diclofenac-choline (DC) has recently been proposed for the symptomatic treatment of oropharyngeal inflammatory processes and pain because its greater water solubility allows the use of high concentrations, which are useful when the contact time between
Leonor C Costa et al.
Environmental science and pollution research international, 22(23), 18574-18589 (2015-09-24)
This study aimed to assess the mechanisms of innate immune function responses to silica-coated iron oxide nanoparticle functionalized with dithiocarbamate groups (IONP) exposure alone and its associated mercury (Hg) in European eel (Anguilla anguilla L.) phagocytes isolated from peritoneum (P-phagocytes)
Erik de Blois et al.
Current topics in medicinal chemistry, 12(23), 2677-2685 (2013-01-24)
An overview how to measure and to quantify radiolysis by the addition of quenchers and to maintain Radio-Chemical Purity (RCP) of vulnerable methionine-containing regulatory peptides is presented. High RCP was only achieved with a combination of quenchers. However, quantification of
Zhen Gao et al.
Biochemical pharmacology, 91(4), 474-482 (2014-08-26)
Palmitic acid, one of the saturated free fatty acids, impairs cardiovascular function as manifested by inducing vascular inflammation, apoptosis and over-production of reactive oxygen species (ROS) although the origin for ROS remains unclear. The present study investigated the cellular mechanisms
Rajendra Kurapati et al.
Small (Weinheim an der Bergstrasse, Germany), 11(32), 3985-3994 (2015-05-12)
Understanding human health risk associated with the rapidly emerging graphene-based nanomaterials represents a great challenge because of the diversity of applications and the wide range of possible ways of exposure to this type of materials. Herein, the biodegradation of graphene
Boyd L O'Dell et al.
Biological trace element research, 152(1), 98-104 (2013-01-08)
Zinc deficiency in 3T3 cells induced by the use of diethylenetriaminepentaacetate (DTPA) has been shown to impair calcium entry associated with failure of proliferation when the cells are stimulated with polypeptide growth factors (GF). These functions of zinc have been
Ezgi Doğan Cömert et al.
Food research international (Ottawa, Ont.), 121, 257-268 (2019-05-22)
This study aimed to investigate the reaction between methylglyoxal and amino acids, polyphenols and sulfur compounds and to provide a new approach for the determination of their dicarbonyl scavenging activities. Various pure compounds and beverages were reacted with methylglyoxal under
Julia E Martin et al.
PLoS genetics, 11(3), e1004977-e1004977 (2015-03-17)
Escherichia coli does not routinely import manganese, but it will do so when iron is unavailable, so that manganese can substitute for iron as an enzyme cofactor. When intracellular manganese levels are low, the cell induces the MntH manganese importer
Yu-Tsai Yang et al.
Carbohydrate polymers, 92(2), 1915-1920 (2013-02-13)
A penta-ethyl ester prodrug of the radionuclide decorporation agent diethylenetriaminepentaacetic acid (DTPA), which exists as an oily liquid, was encapsulated in alginate beads by the ionotropic gelation method. An optimal formulation was found by varying initial concentrations of DTPA penta-ethyl
Karthickeyan Chella Krishnan et al.
Infection and immunity, 82(7), 2992-3001 (2014-05-07)
Streptococcal cysteine protease (SpeB), the major secreted protease produced by group A streptococcus (GAS), cleaves both host and bacterial proteins and contributes importantly to the pathogenesis of invasive GAS infections. Modulation of SpeB expression and/or its activity during invasive GAS
Daniil Karnaushenko et al.
Advanced materials (Deerfield Beach, Fla.), 27(42), 6582-6589 (2015-09-24)
A novel method relying on strain engineering to realize arrays of on-chip-integrated giant magneto-impedance (GMI) sensors equipped with pick-up coils is put forth. The geometrical transformation of an initially planar layout into a tubular 3D architecture stabilizes favorable azimuthal magnetic
Michael R Bukowski et al.
Analytical biochemistry, 469, 54-64 (2014-12-03)
Protein S-glutathionylation is a posttranslational modification that links oxidative stimuli to reversible changes in cellular function. Protein-glutathione mixed disulfide (PSSG) is commonly quantified by reduction of the disulfide and detection of the resultant glutathione species. This methodology is susceptible to
Katsuhiko Sueda et al.
Health physics, 105(2), 208-214 (2013-06-27)
Diethylenetriaminepentaacetic acid (DTPA) is a chelating agent that is used to facilitate the elimination of radionuclides such as americium from contaminated individuals. Its primary site of action is in the blood, where it competes with various biological ligands, including transferrin
Diego Mendez-Gonzalez et al.
Journal of colloid and interface science, 596, 64-74 (2021-04-11)
In this work, we present a luminescence platform that can be used as point of care system for determining the presence and concentration of specific oligonucleotide sequences. This sensor exhibited a limit of detection as low as 50 fM by
Agung Nugroho et al.
Pharmaceutical biology, 53(5), 653-661 (2014-12-05)
Artemisia iwayomogi Kitamura (Compositae) has been very widely used for the treatment of acute or chronic hepatitis, jaundice, and gastritis. In the course of our continuing efforts to identify and quantify peroxynitrite scavengers from Compositae plants, A. iwayomogi was used
Janhvi Pandey et al.
Ecotoxicology and environmental safety, 122, 296-302 (2015-08-25)
A field experiment using tannery sludge as a soil amendment material and palmarosa (Cymbopogon martinii) as a potential phytostabilizer was conducted to investigate their synergistic effect in relation to the improvement in soil quality/property. Three consecutive harvests of two cultivars
Vitaliy B Borisov et al.
Biochimica et biophysica acta, 1847(2), 182-188 (2014-12-03)
Cytochrome bd is a prokaryotic respiratory quinol oxidase phylogenetically unrelated to heme-copper oxidases, that was found to promote virulence in some bacterial pathogens. Cytochrome bd from Escherichia coli was previously reported to contribute not only to proton motive force generation
Gauthier J-P Deblonde et al.
Nature communications, 10(1), 2438-2438 (2019-06-06)
Metal ion separations are critical to numerous fields, including nuclear medicine, waste recycling, space exploration, and fundamental research. Nonetheless, operational conditions and performance are limited, imposing compromises between recovery, purity, and cost. Siderophore-inspired ligands show unprecedented charge-based selectivity and compatibility
Sébastien Leguay et al.
Inorganic chemistry, 51(23), 12638-12649 (2012-11-17)
Complexation of trivalent actinides with DTPA (diethylenetriamine pentaacetic acid) was studied as a function of pcH and temperature in (Na,H)Cl medium of 0.1 M ionic strength. Formation constants of both complexes AnHDTPA(-) and AnDTPA(2-) (where An stands for Am, Cm
Aytül Hamzalıoğlu et al.
Food chemistry, 318, 126467-126467 (2020-03-08)
This study aims to investigate in depth the mechanism of acrylamide formation in coffee during roasting. For this purpose, a comprehensive kinetic model including the elementary steps for acrylamide formation was proposed. The changes in sucrose, reducing sugars, free amino
Jae Sue Choi et al.
Archives of pharmacal research, 37(10), 1354-1363 (2014-07-06)
To investigate the effect of C-glycosylation at different positions of luteolin, the structure-activity relationships of luteolin and a pair of isomeric C-glycosylated derivatives orientin and isoorientin, were evaluated. We investigated the effects of C-glycosylation on the antioxidant, anti-Alzheimer's disease (AD)
Karthik Dhananjayan et al.
Analytical biochemistry, 573, 51-66 (2019-02-24)
Glyoxal (GO) and methylglyoxal (MGO) are two important biomarkers in diabetes. Analytical methods for determination of GO and MGO in serum samples are either HPLC with UV-Vis (low sensitivity) or MS/MS (expensive) detection. These disadvantages have hampered the introduction of
Monal B Shah et al.
Journal of bioscience and bioengineering, 120(2), 167-173 (2015-02-01)
Metal pollution due to the huge electronic waste (E-waste) accumulation is widespread across the globe. Extraction of copper, zinc and nickel from computer printed circuit boards (c-PCB) with a two-step bleaching process using ferric sulphate generated by Leptospirillum ferriphilum dominated
Claire M Doskey et al.
PloS one, 10(7), e0132572-e0132572 (2015-07-15)
The biological consequences upon exposure of cells in culture to a dose of xenobiotic are not only dependent on biological variables, but also the physical aspects of experiments e.g. cell number and media volume. Dependence on physical aspects is often
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