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Showing 1-30 of 329 results for "D2915" within Papers
Dexamethasone affects cell growthapoptosis chemosensitivity of colon cancer via glucocorticoid receptor alphaNF-kappaB
He J, et al.
Testing, 8(40), 67670-67670 (2017)
Aline Fernanda de Souza et al.
Cells, 10(11) (2021-11-28)
Turner syndrome (TS) is a genetic disorder in females with X Chromosome monosomy associated with highly variable clinical features, including premature primary gonadal failure leading to ovarian dysfunction and infertility. The mechanism of development of primordial germ cells (PGCs) and
Regina M Myers et al.
Cancer, 120(9), 1417-1425 (2014-01-30)
The authors prospectively assessed anxiety, depression, and behavior in children with standard-risk acute lymphoblastic leukemia (SR-ALL) during the first year of therapy and identified associated risk factors. A cohort study was performed of 159 children (aged 2 years-9.99 years) with
Florian A Britto et al.
American journal of physiology. Endocrinology and metabolism, 307(11), E983-E993 (2014-10-16)
REDD1 (regulated in development and DNA damage response 1) has been proposed to inhibit the mechanistic target of rapamycin complex 1 (mTORC1) during in vitro hypoxia. REDD1 expression is low under basal conditions but is highly increased in response to
Alice Pham et al.
Obstetrics and gynecology, 120(6), 1451-1458 (2012-11-22)
To estimate the beneficial and harmful effects of dexamethasone for prevention of postoperative nausea and vomiting in women undergoing laparoscopic gynecologic surgery. We searched the following bibliographic databases: MEDLINE (from 1946 to January 2012), Embase (from 1980 to 2012 week
Dongkyun Kim et al.
Immunity, 53(3), 581-596 (2020-07-25)
Glucocorticoids (GC) are the mainstay treatment option for inflammatory conditions. Despite the broad usage of GC, the mechanisms by which GC exerts its effects remain elusive. Here, utilizing murine autoimmune and allergic inflammation models, we report that Foxp3+ regulatory T
Jing Gong et al.
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 29(6), 561-564 (2013-06-12)
To observe the expressions of IL-21 and its receptor (IL-21R) in the lungs of chronic asthmatic mice, and investigate the effects of dexamethasone (Dex) on their expressions. Thirty-three specific pathogen free (SPF) BALB/c female mice were randomly divided into control
Eva Hoster et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(13), 1338-1346 (2014-04-02)
Mantle-cell lymphoma (MCL) is a distinct B-cell lymphoma associated with poor outcome. In 2008, the MCL International Prognostic Index (MIPI) was developed as the first prognostic stratification tool specifically directed to patients with MCL. External validation was planned to be
J R Bellis et al.
British journal of anaesthesia, 113(1), 23-42 (2014-06-20)
Summary In children undergoing tonsillectomy, dexamethasone is recommended to reduce the risk of postoperative nausea and vomiting while non-steroidal anti-inflammatory drugs (NSAIDs) are used for pain relief. We aimed to determine whether children who receive dexamethasone or dexamethasone with NSAID
T Maślanka et al.
Polish journal of veterinary sciences, 16(2), 219-222 (2013-08-27)
Recently, we found that dexamethasone caused a depletion of CD25- CD4+ T cells, but it increased the number of CD25highCD4+ and CD25lowCD4+ T cells. We also determined meloxicam-induced increase in the number of CD25highCD4+ T cells. In view of this
Olivier Aubert et al.
Transplantation, 97(9), 946-952 (2014-04-25)
This prospective monocentric study investigated the effect of corticosteroids plus bortezomib to reduce anti-HLA antibodies before renal transplantation. Included were 23 patients with stable immunization against HLA and awaiting a kidney transplant (KT). Treatment consisted of bortezomib (1.3 mg/m) plus
Jungwook Paek et al.
ACS nano, 13(7), 7627-7643 (2019-06-14)
The vasculature is an essential component of the circulatory system that plays a vital role in the development, homeostasis, and disease of various organs in the human body. The ability to emulate the architecture and transport function of blood vessels
Karen Dendoncker et al.
PloS one, 12(7), e0181101-e0181101 (2017-07-08)
Glucocorticoid resistance (GCR), i.e. unresponsiveness to the beneficial anti-inflammatory activities of the glucocorticoid receptor (GR), poses a serious problem in the treatment of inflammatory diseases. One possible solution to try and overcome GCR, is to identify molecules that prevent or
Chao H Yang et al.
JAMA dermatology, 150(4), 426-428 (2014-02-21)
Cryoglobulins are cold-precipitating immunoglobulins that occur secondary to lymphoproliferative disorders, chronic viral infections, and autoimmune disorders. The treatment of cryoglobulinemia should target the underlying disorder; however, such an approach may be difficult, and therapeutic options remain limited for type I
Pierfrancesco Mirabelli et al.
Experimental eye research, 125, 118-127 (2014-06-17)
Inflammatory angiogenesis is the pathogenic mechanism of various sight-threatening eye diseases, among them corneal neovascularization. Current treatment options include steroids which have undesirable side effects, or anti-VEGF which has only limited efficacy. In an inflammatory environment, however, angiogenesis can be
Lotfi Benboubker et al.
The New England journal of medicine, 371(10), 906-917 (2014-09-04)
The combination melphalan-prednisone-thalidomide (MPT) is considered a standard therapy for patients with myeloma who are ineligible for stem-cell transplantation. However, emerging data on the use of lenalidomide and low-dose dexamethasone warrant a prospective comparison of the two approaches. We randomly
Robert C L N Kramer et al.
Lab on a chip, 20(2), 311-319 (2019-12-07)
Microfluidic atomic force microscopy (AFM) cantilever probes have all the functionalities of a standard AFM cantilever along with fluid pipetting. They have a channel inside the cantilever and an aperture at the tip. Such probes are useful for precise fluid
Andrew Neill et al.
Emergency medicine journal : EMJ, 30(2), 165-166 (2013-01-26)
A short-cut review was carried out to establish whether the administration of dexamethasone reduced the risk of recurrence of migraine headaches at 24 h. Three hundred and fifteen articles were found using the reported search including two systematic reviews and
Clinically relevant genetic advances in endocrinology.
Angela Rogers et al.
Clinical medicine (London, England), 13(3), 299-305 (2013-06-14)
Tae Wook Nam et al.
Acta orthopaedica Belgica, 79(2), 211-215 (2013-07-05)
The authors compared the effect of postoperative administration of corticosteroids (dexamethasone) on prevertebral soft tissue swelling with that of placebo in patients with anterior cervical discectomy and fusion (ACDF). Sixty-two consecutive patients with degenerative disc disease of the cervical spine
Jeffery B Ostler et al.
Journal of virology, 95(4) (2020-11-20)
Following acute infection, herpes simplex virus 1 (HSV-1) lytic cycle viral gene expression is silenced; consequently, lifelong latency in neurons is established. Certain external stimuli that trigger reactivation from latency also activate the glucocorticoid receptor (GR). The synthetic corticosteroid dexamethasone
Tzu-Chieh Chen et al.
The Journal of biological chemistry, 296, 100395-100395 (2021-02-11)
Chronic glucocorticoid exposure causes insulin resistance and muscle atrophy in skeletal muscle. We previously identified phosphoinositide-3-kinase regulatory subunit 1 (Pik3r1) as a primary target gene of skeletal muscle glucocorticoid receptors involved in the glucocorticoid-mediated suppression of insulin action. However, the
Wanderley Marques Bernardo et al.
Revista da Associacao Medica Brasileira (1992), 59(4), 387-391 (2013-07-23)
To verify the efficacy of dexamethasone in the prophylaxis of nausea and vomiting in patients submitted to laparoscopic cholecystectomy. This was a systematic review of the literature through the MEDLINE, Embase, and LILACS databases. Only controlled and randomized clinical trials
[New and old medications for croup and seizures in children. Oral dexamethasone and buccal midazolam may provide better treatment].
Axelsson Inge et al.
Lakartidningen, 110(48), 2163-2163 (2014-01-18)
Yajun Chen et al.
American journal of physiology. Lung cellular and molecular physiology, 306(8), L797-L807 (2014-02-04)
Chronic airway diseases are characterized by inflammation and mucus overproduction. The MUC5AC mucin gene is upregulated by the proinflammatory cytokine interleukin-1 β (IL-1β) via activation of cAMP response element-binding protein (CREB) in the NCI-H292 cancer cell line and nuclear factor-κB
Chenming Yang et al.
Journal of biomedical nanotechnology, 9(9), 1617-1623 (2013-08-29)
The purpose of this research was to investigate the possibility of dexamethasone (DEX)-loaded PLGA-TPGS nanoparticles (NPs) in rabbits after intravitreal administration for the treatment of posterior segment diseases. The DEX-loaded PLGA-TPGS NPs were fabricated and characterized in terms of surface
Kasima Ekthuwapranee et al.
The Journal of steroid biochemistry and molecular biology, 145, 38-48 (2014-10-12)
Glucocorticoids, hormones that are released in response to stress, induce neuronal cell damage. The hippocampus is a primary target of glucocorticoids in the brain, the effects of which include the suppression of cell proliferation and diminished neurogenesis in the dentate
Denise Martinez Alanis et al.
Nature communications, 5, 3923-3923 (2014-06-01)
The lung is a branched tubular network with two distinct compartments--the proximal conducting airways and the peripheral gas exchange region--separated by a discrete boundary termed the bronchoalveolar duct junction (BADJ). Here we image the developing mouse lung in three-dimensions (3D)
Jennifer E Flower et al.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 44(4), 1115-1119 (2014-01-24)
A 10-yr-old female spayed mixed breed tiger presented for a 9-day history of acute and nonprogressive paralysis of the pelvic limbs. Magnetic resonance imaging revealed a lesion suggestive of fibrocartilaginous embolic myelopathy with regional spinal cord edema, decreased disk signal
Yasunobu Sekiguchi et al.
Journal of clinical and experimental hematopathology : JCEH, 53(1), 21-28 (2013-06-27)
A 56-year-old man developed epistaxis, hoarseness, and swelling of a finger in March 2010. On the basis of biopsies of the masses in the pharynx and finger, he was diagnosed with extramedullary plasmablastic plasmacytoma, with somewhat immature CD45(+), MPC-1(-), and
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