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Showing 1-30 of 155 results for "E1620000" within Papers
Kara J Connelly et al.
Endocrinology, 156(1), 193-202 (2014-10-21)
Peak bone mass, one of the most important predictors for fracture risk later in life, is attained during puberty and adolescence and influenced by neonatal and pubertal sex-specific gonadal hormones and GH-IGF-I secretion patterns. This study examined the effects of
Jeremy K Larson et al.
Nanotoxicology, 8(8), 856-866 (2013-09-03)
Gold nanoparticles (GNPs) have gained considerable attention for application in science and industry. However, the untoward effects of such particles on female fertility remain unclear. The objectives of this study were to (1) examine the effects of 10-nm GNPs on
Xuefang Liang et al.
Environmental pollution (Barking, Essex : 1987), 189, 184-193 (2014-04-01)
Assessing protein responses to endocrine disrupting chemicals is critical for understanding the mechanisms of chemical action and for the assessment of hazards. In this study, the response of the liver proteome of male rare minnows (Gobiocypris rarus) treated with 17β-estradiol
Lianguo Chen et al.
Aquatic toxicology (Amsterdam, Netherlands), 149, 116-125 (2014-03-04)
This study evaluated the potential adverse effects of butenolide, a promising antifouling compound, using the marine medaka (Oryzias melastigma), a model fish for marine ecotoxicology. The active ingredient used in the commercial antifoulant SeaNine 211, 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) was employed as
Joel S Finkelstein et al.
The New England journal of medicine, 369(11), 1011-1022 (2013-09-13)
Current approaches to diagnosing testosterone deficiency do not consider the physiological consequences of various testosterone levels or whether deficiencies of testosterone, estradiol, or both account for clinical manifestations. We provided 198 healthy men 20 to 50 years of age with
Laura Ballester et al.
Fertility and sterility, 102(6), 1762-1768 (2014-09-23)
To determine optimal conditions for the inclusion of oviductal fluid (OF) in IVF protocols. Experimental prospective study. Mammalian reproduction research laboratory. Oviducts and ovaries from porcine females were collected at a slaughterhouse. A total of 30 oviducts and 1,285 oocytes
Baojian Xue et al.
American journal of physiology. Heart and circulatory physiology, 307(2), H191-H198 (2014-05-27)
This study investigated sex differences in the sensitization of angiotensin (ANG) II-induced hypertension and the role of central estrogen and ANG-(1-7) in this process. Male and female rats were implanted for telemetered blood pressure (BP) recording. A subcutaneous subpressor dose
Brian P Kenealy et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(49), 19051-19059 (2013-12-07)
Release of gonadotropin releasing hormone (GnRH) from the medial basal hypothalamus (MBH)/median eminence region (S-ME) is essential for normal reproductive function. GnRH release is profoundly regulated by the negative and positive feedback effects of ovarian estradiol (E2). Here we report
On estrogen, cholesterol metabolism, and breast cancer.
Margaret Warner et al.
The New England journal of medicine, 370(6), 572-573 (2014-02-07)
Coadministrating luteolin minimizes the side effects of the aromatase inhibitor letrozole.
Li F, Wong TY, Lin SM, et al.
Journal of Pharmacology and Experimental Therapeutics, 351(2), 270-277 (2014)
Kathryn J Grive et al.
Developmental biology, 392(1), 42-51 (2014-05-20)
Primary ovarian insufficiency (POI) affects 1% of women under the age of 40 and is associated with premature ovarian follicle depletion. TAF4b deficiency in adult female mouse models results in hallmarks of POI including stereotyped gonadotropin alterations indicative of early
Bu B Yeap et al.
The Journal of clinical endocrinology and metabolism, 99(1), E9-18 (2013-11-22)
Testosterone (T) levels decline with age and lower T has been associated with increased mortality in aging men. However, the associations of its metabolites, dihydrotestosterone (DHT) and estradiol (E2), with mortality are poorly defined. We assessed associations of T, DHT
Seiro Satohisa et al.
Endocrinology, 155(8), 3005-3016 (2014-06-01)
Adduction of a nitric oxide (NO) moiety (NO(•)) to cysteines termed as S-nitrosylation (SNO) has emerged as a crucial mechanism for NO signaling crucial for mediating the vascular effects of estrogens. Mitochondrion is a known vascular risk factor; however, the
Gonadal steroids and body composition, strength, and sexual function in men.
Paul F Schellhammer
The New England journal of medicine, 369(25), 2456-2456 (2013-12-20)
Characterization of the zebrafish Ugt repertoire reveals a new class of drug-metabolizing UDP glucuronosyltransferases.
Wang Y, Huang H, and Wu Q
Molecular Pharmacology, 86(1), 62-75 (2014)
Wenbo Li et al.
Nature, 498(7455), 516-520 (2013-06-04)
The functional importance of gene enhancers in regulated gene expression is well established. In addition to widespread transcription of long non-coding RNAs (lncRNAs) in mammalian cells, bidirectional ncRNAs are transcribed on enhancers, and are thus referred to as enhancer RNAs
Zhonghua Shi et al.
Endocrinology, 155(5), 1982-1990 (2014-03-08)
Omental adipose tissue plays a central role in insulin resistance in gestational diabetes mellitus (GDM), and the molecular mechanisms leading to GDM remains vague. Evidence demonstrates that maternal hormones, such as estradiol, contribute to insulin resistance in GDM. In this
Mariana Nigro et al.
Endocrinology, 155(8), 2881-2891 (2014-06-11)
Menopause is associated with increased visceral adiposity and disrupted glucose homeostasis, but the underlying molecular mechanisms related to these metabolic changes are still elusive. Brown adipose tissue (BAT) plays a key role in energy expenditure that may be regulated by
Irene Kwan et al.
The Cochrane database of systematic reviews, 8(8), CD005289-CD005289 (2014-08-26)
Traditional monitoring of ovarian hyperstimulation during in vitro fertilisation (IVF) and intra-cytoplasmic sperm injection (ICSI) treatment has included transvaginal ultrasonography (TVUS) plus serum estradiol levels to ensure safe practice by reducing the incidence and severity of ovarian hyperstimulation syndrome (OHSS)
Aniruddha Das et al.
Archives of sexual behavior, 43(7), 1403-1415 (2014-03-07)
Using nationally representative data from the 2005-2006 U.S. National Social Life, Health, and Aging Project, this study queried relationship, sexual, and sex hormone patterns among married evangelical women and men aged 57-85, relative to those in other religions. Results suggested
Lydia M M Vermeer et al.
Experimental neurology, 263, 8-16 (2014-09-30)
Migraine is one of the most common neurological disorders, leading to more than 1% of total disability reported and over 68 million visits to emergency rooms or physician's offices each year in the United States. Three times as many women
Gonadal steroids and body composition, strength, and sexual function in men.
Joel S Finkelstein et al.
The New England journal of medicine, 369(25), 2457-2457 (2013-12-20)
Susan H Corbett et al.
Southern medical journal, 107(7), 433-436 (2014-07-11)
To identify trends in compounding pharmacies with a focus on women's health and, more specifically, the types and combinations of medications used in the treatment of vulvodynia. This survey study was conducted with 653 nonchain pharmacies that compound medications. Each
Juan M Fregeneda-Grandes et al.
Journal of water and health, 11(4), 720-728 (2013-12-18)
Serum steroid profiles were investigated in order to evaluate the potential use of circulating sex steroid levels as a tool for sex identification in brown trout. Changes in the serum concentrations of testosterone (T), progesterone (P), 17-β-estradiol (E2), and cortisol
Estrogens and myocardial chymase: new insights into pathological hypertrophy and remodeling.
Jorge E Jalil et al.
Hypertension (Dallas, Tex. : 1979), 65(2), 271-272 (2014-11-19)
Iu O Kovaleva et al.
Eksperimental'naia i klinicheskaia farmakologiia, 76(5), 7-9 (2013-08-02)
We have studied the role of female sex hormone estradiol in the development of hypoxic pulmonary arterial hypertension. Previously, it was shown that the development of pulmonary hypertension in Wistar female rats is accompanied by a twofold increase in the
Venkataraman Sriraman et al.
Biochemical pharmacology, 89(2), 266-275 (2014-03-19)
FSH signalling through its cognate receptor is critical for follicular development and ovulation. An earlier study had documented thiazolidinone derivatives to activate FSH receptor expressed in CHO cells and rat granulosa cells; however development of this compound for clinical use
Shuzo Hirata et al.
Nature materials, 13(10), 938-946 (2014-09-10)
In materials showing reverse saturable absorption (RSA), the optical absorbance increases as the power of the light incident on them increases. To date, RSA has only been observed when very intense light sources, such as short-pulse lasers, are used. Here
Maren S Fragala et al.
The journals of gerontology. Series A, Biological sciences and medical sciences, 70(2), 202-209 (2014-08-20)
The Foundation for the National Institutes of Health Sarcopenia Project developed data-driven cut-points for clinically meaningful weakness and low lean body mass. This analysis describes strength and function response to interventions based on these classifications. In data from four intervention
K Schulz et al.
Die Pharmazie, 68(5), 311-316 (2013-06-28)
For estradiol (E2) the separation of the degradation products delta6- and delta9,11-E2 is especially challenging due to their structural similarity. There is no method described in the literature yet which adequately addresses this problem. The present study describes a HPLC
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