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Showing 1-30 of 603 results for "F9037" within Papers
Ana Carolina Acevedo et al.
BMC medical genetics, 16, 8-8 (2015-05-01)
Raine syndrome (RS) is a rare autosomal recessive bone dysplasia typified by osteosclerosis and dysmorphic facies due to FAM20C mutations. Initially reported as lethal in infancy, survival is possible into adulthood. We describe the molecular analysis and clinical phenotypes of
Jarmila Krojerová-Prokešová et al.
The Journal of heredity, 106(4), 375-385 (2015-04-29)
Due to a restriction of the distributional range of European red deer (Cervus elaphus L.) during the Quaternary and subsequent recolonization of Europe from different refugia, a clear phylogeographical pattern in genetic structure has been revealed using mitochondrial DNA markers.
Fatemah Chehrehasa et al.
Journal of neuroscience methods, 177(1), 122-130 (2008-11-11)
Labelling and identifying proliferating cells is central to understanding neurogenesis and neural lineages in vivo and in vitro. We present here a novel thymidine analogue, ethynyl deoxyuridine (EdU) for labelling dividing cells, detected with a fluorescent azide which forms a
Qiaoran Li et al.
Current biology : CB, 31(9), 1850-1861 (2021-03-04)
An animal's decision to accept or reject a prospective food is based only, in part, on its chemical composition. Palatability is also greatly influenced by textural features including smoothness versus grittiness, which is influenced by particle sizes. Here, we demonstrate
Yusuke Hagiwara et al.
Canadian journal of microbiology, 61(10), 735-743 (2015-07-18)
Fungal decomposition of lignin leads to the whitening, or bleaching, of leaf litter, especially in temperate and tropical forests, but less is known about such bleaching in forests of cooler regions, such as boreal and subalpine forests. The purposes of
Sadia Bekal et al.
The Journal of general virology, 95(Pt 6), 1272-1280 (2014-03-20)
Heterodera glycines, the soybean cyst nematode (SCN), is a subterranean root pathogen that causes the most damaging disease of soybean in the USA. A novel nematode virus genome, soybean cyst nematode virus 5 (SbCNV-5), was identified in RNA sequencing data
Laura E Blue et al.
Journal of chromatography. A, 1380, 71-80 (2015-01-13)
The predicted advantages of superficially porous particles over totally porous particles are decreased eddy dispersion, longitudinal diffusion, and resistance to mass transfer contributions to the theoretical plate height. While sub-2 micron superficially porous particles are commercially available, further improvements in
Ye Yan et al.
Nature communications, 6, 7006-7006 (2015-05-07)
Neural progenitors and terminally differentiated neurons show distinct redox profiles, suggesting that coupled-redox cascades regulate the initiation and progression of neuronal differentiation. Discrete cellular compartments have different redox environments and how they contribute to differentiation is unclear. Here we show
Junpei Kimura et al.
Scientific reports, 4, 7290-7290 (2014-12-04)
Members of the Toll-like receptor (TLR) family serve as pathogen sensors and participate in local autoimmune responses. This study found a correlation between glomerular injury and TLR expression by analysing BXSB/MpJ-Yaa (BXSB-Yaa) lupus model mice. In isolated glomeruli, the mRNA
Sandy R Shultz et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 35(8), 1339-1347 (2015-04-09)
Multitrauma is a common medical problem worldwide, and often involves concurrent traumatic brain injury (TBI) and bone fracture. Despite the high incidence of combined TBI and fracture, preclinical TBI research commonly employs independent injury models that fail to incorporate the
Ana Vieira-da-Silva et al.
Cytogenetic and genome research, 145(1), 59-67 (2015-05-23)
Compared to humans and other mammals, rodent genomes, specifically Muroidea species, underwent intense chromosome reshuffling in which many complex structural rearrangements occurred. This fact makes them preferential animal models for studying the process of karyotype evolution. Here, we present the
Paige S Katz et al.
Journal of neurotrauma, 32(5), 297-306 (2014-08-29)
Traumatic brain injury (TBI) is an increasingly frequent and poorly understood condition lacking effective therapeutic strategies. Inflammation and oxidative stress (OS) are critical components of injury, and targeted interventions to reduce their contribution to injury should improve neurobehavioral recovery and
Francesca Palombo et al.
The journal of physical chemistry. B, 116(45), 13481-13489 (2012-10-24)
Molecular dynamics of formamide solutions of alkali metal halide salts were investigated using the time-resolved ultrafast optical Kerr effect (OKE) to observe the effects of ion solvation on the dynamics of a nonaqueous high-permittivity H-bonding solvent. The picosecond orientational and
Brandon L Blakely et al.
Nature methods, 11(12), 1229-1232 (2014-10-13)
We developed molecular tension probes (TPs) that report traction forces of adherent cells with high spatial resolution, can in principle be linked to virtually any surface, and obviate monitoring deformations of elastic substrates. TPs consist of DNA hairpins conjugated to
Haiya Yang et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 31(10), 1005-1010 (2015-10-16)
One way to determine the pH at the air/water interface with a confocal fluorescence microscope has been proposed. The relation between the pH at the air/water interface and that in a bulk solution has been formulated in connection with the
Javier Pérez-González et al.
PloS one, 9(12), e115394-e115394 (2014-12-30)
The maintenance of genetic diversity across generations depends on both the number of reproducing males and females. Variance in reproductive success, multiple paternity and litter size can all affect the relative contributions of male and female parents to genetic variation
Christopher Beck et al.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 272(10), 2765-2776 (2014-09-13)
The prevalence of hearing impairment is estimated as approximately 1 on 1,000 newborn children. To assess a higher mutation detection rate in individuals with hearing loss a three-step mutation screening program consisting of GJB2 in first line, then GJB1, GJB3
Karen Mendelson et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 244(8), 948-954 (2015-05-23)
The sphingosine 1-phosphate (S1P) signaling pathway regulates zebrafish cardiogenesis, and provides a paradigm for how signaling gradients coordinate collective cell migration across tissue layers. It is known that the S1P transporter (Spns2) functions in extra-embryonic YSL to activate G protein-coupled
Preethi S Nair et al.
PloS one, 9(5), e97337-e97337 (2014-05-23)
Despite increased awareness and diagnostic facilities, 70-80% of the haemophilia A (HA) patients still remain undiagnosed in India. Very little data is available on prevalent mutations in HA from this country. We report fifty mutations in seventy one Indian HA
A Touati et al.
Journal of clinical microbiology, 53(10), 3182-3194 (2015-07-24)
Molecular typing of Mycoplasma pneumoniae is an important tool for identifying grouped cases and investigating outbreaks. In the present study, we developed a new genotyping method based on single nucleotide polymorphisms (SNPs) selected from the whole-genome sequencing of eight M.
Armen Y Mulkidjanian et al.
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 42(5), 507-516 (2012-11-08)
We have recently reconstructed the 'hatcheries' of the first cells by combining geochemical analysis with phylogenomic scrutiny of the inorganic ion requirements of universal components of modern cells (Mulkidjanian et al. Proc Natl Acad Sci U S A 109:E821-830, 2012).
André Barretto Bruno Wilke et al.
Parasites & vectors, 7, 468-468 (2014-10-05)
Culex quinquefasciatus mosquitoes can be found in almost every major city of Brazil and are vectors of filariasis and several arboviruses. Microsatellite markers have been widely used to uncover the genetic structure of various groups of insect populations. The aim
Carlos O Jacobo-Cabral et al.
Pediatric transplantation, 18(7), 706-713 (2014-08-27)
The aim of this study was to evaluate the bioavailability of two oral tacrolimus formulations, the innovator Prograf(®) and a formulation commercialized in Mexico with the brand name Limustin(®), in children. Stable Mexican pediatric renal transplant recipients received the product
Alexis Poncy et al.
Developmental biology, 404(2), 136-148 (2015-06-03)
In developing liver, cholangiocytes derive from the hepatoblasts and organize to form the bile ducts. Earlier work has shown that the SRY-related High Mobility Group box transcription factor 9 (SOX9) is transiently required for bile duct development, raising the question
Jeffery W Bacher et al.
PloS one, 10(8), e0132727-e0132727 (2015-08-08)
Microsatellite instability (MSI) occurs in over 90% of Lynch syndrome cancers and is considered a hallmark of the disease. MSI is an early event in colon tumor development, but screening polyps for MSI remains controversial because of reduced sensitivity compared
Mario Mietzsch et al.
Human gene therapy, 26(10), 688-697 (2015-07-03)
Scalable production of recombinant adeno-associated virus vectors (rAAV) in baculovirus-infected Sf9 cells yields high burst sizes but variable infectivity rates per packaged AAV vector genome depending on the chosen serotype. Infectivity rates are particularly low for rAAV5 vectors, based on
Danielle Carpenter et al.
Human molecular genetics, 24(12), 3472-3480 (2015-03-20)
The human salivary amylase genes display extensive copy number variation (CNV), and recent work has implicated this variation in adaptation to starch-rich diets, and in association with body mass index. In this work, we use paralogue ratio tests, microsatellite analysis
Lisa A Poole et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(48), 14864-14869 (2015-11-19)
The SMARCAL1 (SWI/SNF related, matrix-associated, actin-dependent, regulator of chromatin, subfamily A-like 1) DNA translocase is one of several related enzymes, including ZRANB3 (zinc finger, RAN-binding domain containing 3) and HLTF (helicase-like transcription factor), that are recruited to stalled replication forks
Kai-Lian Zheng et al.
International journal of clinical and experimental pathology, 8(6), 6181-6191 (2015-08-12)
Pancreatic ductal adenocarcinoma (PDAC) is the most common form of malignancy in pancreatic carcinoma. Here we report our discovery on the correlations between transcriptional alternative splicing (AS) of NUMB, APP, VEGFA and PDAC in patients. The expression of NUMB, APP
Roberta Lattanzi et al.
BioMed research international, 2015, 301292-301292 (2015-02-17)
The new chemokine Prokineticin 2 (PROK2) and its receptors (PKR1 and PKR2) have a role in inflammatory pain and immunomodulation. Here we identified PROK2 as a critical mediator of neuropathic pain in the chronic constriction injury (CCI) of the sciatic
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