Identify and correct common HPLC problems to restore column performance. Get help with peak problems (peak splitting, peak tailing, peak fronting, etc.), retention time, purge noise, and loss of resolution with example chromatograms.
A sensitive LC-MS/MS quantitative method for the simultaneous analysis of highly polar 11 nucleotide activated sugars having similar structures and physicochemical properties using Supel™ Carbon LC column.
The sample complexity makes it important to use highly-efficient, highly-selective phases and columns that are compatible with different detection systems to maximize the information from HPLC experiments. Ascentis Express Fused-Core® columns meet these requirements.
Polar graphitic carbon (2.7 μm) based Ultra/High-performance liquid chromatographic separation of four highly polar pesticides, two polar herbicides―paraquat & diquat, and Vitamin D and its metabolites.
Nitrosamines have been discovered as a serious contaminant group in active pharmaceutical ingredients (API) belonging to the sartan family. This article describes a GC-MS method for the determination of nitrosamines in Valsartan tablets according to US FDA guide lines that
A sensitive and reproducible HPLC-DAD method for the purity analysis of safinamide and its related impurities using an Ascentis® Express C8 column (150 x 4.6 mm, 5 μm), meeting the system suitability criteria.
The Milliflex Oasis® filtration system is a complete solution for monitoring in-process samples, water, filtrable raw materials, and finished products for bioburden and microbial limits testing. The system increases QC lab productivity while reducing the risk of false results.