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Dynamic Live Cell Imaging of Caspase Mediated Apoptosis and Cellular Hypoxia in Lymphocytes and Cancer Cells Using the CellASIC® ONIX2 Microfluidic Platform
Application note on how the CellASIC® ONIX2 microfluidic system can be used to analyze caspase-3 mediated apoptosis/cell death and cellular hypoxia in live immune and cancer cell lines.
Metal Hydrides for NiMH Battery Applications
Rechargeable solid-state batteries are becoming increasingly important due to wide-spread use in computers, portable electronics, and vehicular applications.
Materials for Thin Film Solid Oxide Fuel Cells (TF-SOFCs)
This technical spotlight focuses on the thin film solid oxide fuel cells (TF-SOFC). TF-SOFCs refer to solid oxide fuel cells with electrolyte thin films. This review highlights technical advantages of TF-SOFC and introduces deposition methods of electrolyte thin films to
Recent Developments in Silicon Anode Materials for High Performance Lithium-Ion Batteries
Recent demand for electric and hybrid vehicles, coupled with a reduction in prices, has caused lithium-ion batteries (LIBs) to become an increasingly popular form of rechargeable battery technology.
Advancements in Quantum Dot Solar Cells
Professor Sharma and colleagues review the synthesis and applications of this novel material. This includes a discussion of the unique properties of quantum dots and their suitability for solar cell applications, along with common synthesis techniques used to develop these
Vibrio Detection
Vibrios are motile, curved or comma-shaped bacilli and have a single polar flagella with sheet proteins. They are often found in open water, freshwater and saltwater.
Surface-enhanced Solar Energy Conversion Systems Using Gold and Silver Nanoparticles
Sustainable, environment-friendly, and clean energy sources with sufficiently high production efficiency for practical application are highly desirable to meet the energy challenge of the 21st century due to the world′s increasing energy demand.
Olivine-Type Cathode Materials for Lithium-Ion Batteries
Lithium-ion batteries (LIBs) have been widely adopted as the most promising portable energy source in electronic devices because of their high working voltage, high energy density, and good cyclic performance.
Detection, identification, differentiation and cultivation of Yersinia species
Detection, identification, differentiation and cultivation of Yersinia species
Stable Isotope Labeled Fatty Acids as Metabolic Tracers presents an article about Stable Isotope labeled fatty acids and triglycerides can be used as tracers to follow the metabolism of dietary fat.
Drug transport assays in a 96-well system: reproducibility and correlation to human absorption
Application note on Drug transport assays in a 96-well system using Millicell-96 System from Millipore.
Inhibition of Nucleic Acid Synthesis by Antibiotics
Quinolones are a key group of antibiotics that interfere with DNA synthesis by inhibiting topoisomerase, most frequently topoisomerase II (DNA gyrase), an enzyme involved in DNA replication.
Insulin Signaling and Energy Homeostasis
Glucose metabolism is regulated by the opposing actions of insulin and glucagon. Insulin is released from pancreatic ß cells in response to high blood glucose levels and regulates glucose metabolism through its actions on muscle, liver, and adipose tissue.
Cholesterol Biosynthesis
Biosynthesis of cholesterol generally takes place in the endoplasmic reticulum of hepatic cells and begins with acetyl- CoA, which is mainly derived from an oxidation reaction in the mitochondria. Acetyl-CoA and acetoacetyl-CoA are converted to 3-hydroxy- 3-methylglutaryl-CoA (HMG-CoA) by HMG-CoA
Bile Acids
The liver excretes excess cholesterol in the form of bile acids. Bile acids serve two purposes: to remove unwanted cholesterol from the body and to aid in lipid digestion in the intestine.
Immuno Oncology Research Tools and Solutions
Whether you need screening tools for CAR/TCR therapies and mAB development, target cells for efficacy testing, or potency assays for clinical development, we provide functional biologically-relevant solutions to help you save time, accelerate your immuno-oncology research, and simplify your workflow.
Angiotensin Receptors
We offer many products related to angiotensin receptors for your research needs.
Although actin is one of the most conserved eukaryotic proteins, it is expressed as six isoforms characterized by electrophoresis and amino acid sequence analysis. Four of the six isoforms represent differentiation markers of muscle tissues. The other two are found
Acetylcholine Receptors (Muscarinic)
Muscarinic acetylcholine receptors are G protein-coupled receptors (GPCRs) and mediate acetylcholine actions in the CNS and non-nervous tissues. Learn more about acetylcholine receptors and their role in cell signaling.
Handling and Storage Guidelines for Peptides and Proteins
Handling and Storage Guidelines for Peptides and Proteins
Nanodisc Technology: A Revolutionary System for Study of Membrane Proteins
Read our article about how the Nanodisc system allows for structural studies of membrane proteins.
Parahydrogen Induced Polarization
Parahydrogen Induced Polarization (PHIP) is a hyperpolarization technique, where the nuclear singlet state of parahydrogen is used as a source of hyperpolarization.
Papain, Cysteine Protease, Properties & Products
Papain is a cysteine protease of the peptidase C1 family. Papain consists of a single polypeptide chain with three disulfide bridges and a sulfhydryl group necessary for activity of the enzyme.
Folic Acid Metabolism in Cancer
This issue of Biofiles reviews some of our newest and most innovative technologies and their specific applications toward cancer research. In preparing this issue of Biofiles, one is reminded how complex the disease of cancer is, and how difficult it
Interleukin Family (IL)
The Interleukins comprise a disparate group of cytokines and growth factors that are produced by and released from leukocytes. Interleukin-1β (1L-1β) is released primarily from stimulated macrophages and monocytes and plays a key role in inflammatory and immune responses and
DNA Damage and Repair
DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.
Troponin together with tropomyosin, regulate the binding of myosin to actin. Troponin is a trimeric protein composed of Troponin subunits I, C and T. Troponin C binds calcium ions, Troponin T binds to tropomyosin and troponin I binds
Isoprene Biosynthesis
Two metabolic pathways exist for the biosynthesis of isopentenyl pyrophosphate and dimethylallyl pyrophosphate: The mevalonate pathway, predominantly used by plants and in a few insect species. The non-mevalonate pathway or methyl D-erythritol 4-phosphate (MEP) pathway, which occurs in plant chloroplasts
Tec kinases represent the second largest family of nonreceptor tyrosine kinases and are activated in response to cellular stimulation by antigen receptors, integrins, growth factors, cytokines and G protein-coupled receptors.
Angiostatin and Endostatin: Key Players in a Dual Threat Approach to Cancer Treatment
Anticancer drugs development - natural and synthetic angiogenesis inhibitors.
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