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fibroblast growth factor 10
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Showing 1-30 of 29632 results for "fibroblast growth factor 10" within Papers
Kazuto Suda et al.
BMC urology, 23(1), 169-169 (2023-10-25)
Dysregulation of the terminal differentiation of bladder urothelium is associated with the pathogenesis of urinary tract disorders. Fibroblast growth factor (Fgf)7 and Fgf10 stimulate urothelial proliferation; however, their roles in cellular differentiation remain unclear. In this study, we used an
Cho-Ming Chao et al.
The Journal of pathology, 241(1), 91-103 (2016-10-23)
Inflammation-induced FGF10 protein deficiency is associated with bronchopulmonary dysplasia (BPD), a chronic lung disease of prematurely born infants characterized by arrested alveolar development. So far, experimental evidence for a direct role of FGF10 in lung disease is lacking. Using the
C Marchese et al.
The Journal of investigative dermatology, 116(4), 623-628 (2001-04-05)
Fibroblast growth factor 10 is a novel member of the fibroblast growth factor family, which is involved in morphogenesis and epithelial proliferation. It is highly homologous to the keratinocyte growth factor (or fibroblast growth factor 7), a key mediator of
Toshiyuki Ishiwata et al.
Experimental and molecular pathology, 73(3), 181-190 (2003-02-05)
The regenerative process of the pancreas after acute pancreatitis (AP) is characterized by acinar and ductal cell proliferation with synthesis and transient deposition of extracellular matrices. Various growth factors were reported to be highly expressed in AP, but their regulation
Lujun Yang et al.
Skin pharmacology and physiology, 31(5), 229-237 (2018-05-31)
To elucidate the possible mechanisms of how basic fibroblast growth factor (bFGF) influences epidermal homeostasis in a living skin equivalent (LSE) model. Several wound healing-related growth factors were analyzed at protein and mRNA levels for dermal fibroblasts of induced alpha-smooth
D Kovacs et al.
Experimental dermatology, 14(2), 130-137 (2005-02-01)
The pathogenic mechanism underlying the hyperproliferation of keratinocytes in psoriasis is still not completely clarified. The production of cytokines released by activated T lymphocytes infiltrating the upper dermis probably has a crucial role. Even dermal fibroblasts can participate in the
M Mongiat et al.
The Journal of biological chemistry, 275(10), 7095-7100 (2000-03-04)
Perlecan is a multifaceted heparan sulfate proteoglycan that is expressed not only as an intrinsic constituent of basement membranes but also as a cell-surface and pericellular proteoglycan. Perlecan functions as a ligand reservoir for various growth factors that become stabilized
Peter L Santa Maria et al.
Journal of molecular histology, 42(1), 47-58 (2010-12-08)
The aim of this study was to provide a transcriptome profile of Keratinocyte Growth Factor (KGF)-1, Fibroblast Growth Factor (FGF) 2 and FGF10 (KGF2) in the healing rat tympanic membrane (TM) over 7 days and an immunohistochemical account over 14
Joanne Watson et al.
Nature communications, 13(1), 6589-6589 (2022-11-05)
Receptor Tyrosine Kinase (RTK) endocytosis-dependent signalling drives cell proliferation and motility during development and adult homeostasis, but is dysregulated in diseases, including cancer. The recruitment of RTK signalling partners during endocytosis, specifically during recycling to the plasma membrane, is still
Mouse Fgf7 (fibroblast growth factor 7) and Fgf8 (fibroblast growth factor 8) genes map to chromosomes 2 and 19 respectively.
M G Mattei et al.
Mammalian genome : official journal of the International Mammalian Genome Society, 6(3), 196-197 (1995-03-01)
J Buratini et al.
Biology of reproduction, 77(4), 743-750 (2007-06-22)
Some fibroblast growth factors (FGFs) affect ovarian follicle cell growth and/or differentiation. Whereas many FGFs activate several FGF receptors, FGF7 and FGF10 primarily activate only one, FGFR2B. As FGF7 is produced by bovine theca cells and acts on granulosa cells
R C Burns et al.
Developmental biology, 265(1), 61-74 (2003-12-31)
Epithelial-mesenchymal interactions are critical for the formation of gastrointestinal buds such as the cecum from the midgut, but the mechanisms regulating this process remain unclear. To investigate this problem, we have studied the temporal and spatial expression of key genes
S Bellusci et al.
Development (Cambridge, England), 124(23), 4867-4878 (1998-01-15)
During mouse lung morphogenesis, the distal mesenchyme regulates the growth and branching of adjacent endoderm. We report here that fibroblast growth factor 10 (Fgf10) is expressed dynamically in the mesenchyme adjacent to the distal buds from the earliest stages of
D Ron et al.
The Journal of biological chemistry, 268(8), 5388-5394 (1993-03-15)
A cDNA predicted to encode a transmembrane tyrosine kinase receptor with sequence features characteristic of known fibroblast growth factor (FGF) receptors was isolated from an expression library constructed from the human mammary epithelial cell line B5/589. This cDNA, designated cl44
Gulsan Ara Sathi et al.
Journal of cell science, 130(9), 1559-1569 (2017-03-30)
The importance of macrophages in tissue development and regeneration has been strongly emphasized. However, the specific roles of macrophage colony-stimulating factor (MCSF), the key regulator of macrophage differentiation, in glandular tissue development have been unexplored. Here, we disclose new macrophage-independent
M Kanai et al.
The American journal of physiology, 272(4 Pt 1), G885-G893 (1997-04-01)
Proliferation and function of the intestinal epithelium is modulated by a range of regulatory peptides, including cytokines and peptide growth factors. To define mechanisms integrating these regulatory systems, the effects of growth factors and cytokines on the expression of the
D P Bottaro et al.
The Journal of biological chemistry, 265(22), 12767-12770 (1990-08-05)
Keratinocyte growth factor (KGF) is a member of the fibroblast growth factor (FGF) family. KGF exhibits potent mitogenic activity for a variety of epithelial cell types but is distinct from other known FGFs in that it is not mitogenic for
M Igarashi et al.
The Journal of biological chemistry, 273(21), 13230-13235 (1998-05-28)
A newly identified member of the fibroblast growth factor (FGF) family, designated FGF-10, is expressed during development and preferentially in adult lung. The predicted FGF-10 protein is most related to keratinocyte growth factor (KGF, or FGF-7). The latter is unique
Hideyo Ohuchi et al.
Biochemical and biophysical research communications, 302(3), 562-567 (2003-03-05)
Fibroblast Growth Factor (FGF) signaling is known to play an important role during cutaneous development. To elucidate the role of FGF10 during whisker formation, we examined the expression of Fgf10 in normal developing whiskers and phenotypes of Fgf10-deficient whiskers. Fgf10
Stephen E McGowan et al.
American journal of physiology. Lung cellular and molecular physiology, 309(5), L463-L474 (2015-07-04)
Pulmonary alveolar fibroblasts produce extracellular matrix in a temporally and spatially regulated pattern to yield a durable yet pliable gas-exchange surface. Proliferation ensures a sufficient complement of cells, but they must differentiate into functionally distinct subtypes: contractile myofibroblasts (MF), which
Assignment of mouse fibroblast growth factor 10 (Fgf10) gene to the telomeric region of chromosome 13.
M A Crackower et al.
Genomics, 53(2), 247-248 (1998-10-29)
Shuichi Hashimoto et al.
Pathobiology : journal of immunopathology, molecular and cellular biology, 79(3), 127-143 (2012-01-21)
Signaling by fibroblast growth factor (FGF) receptor (FGFR) 2IIIb regulates branching morphogenesis in the mammalian lung. FGFR2IIIb is primarily expressed in epithelial cells, whereas its ligands, FGF-10 and keratinocyte growth factor (KGF; FGF-7), are expressed in mesenchymal cells. FGF-10 null
Keratinocyte growth factor. A fibroblast growth factor family member with unusual target cell specificity.
S A Aaronson et al.
Annals of the New York Academy of Sciences, 638, 62-77 (1991-01-01)
S E Wilson et al.
Investigative ophthalmology & visual science, 34(8), 2544-2561 (1993-07-01)
The purpose of this study was to determine whether messenger RNA coding for hepatocyte growth factor (HGF), HGF receptor (MET), keratinocyte growth factor (KGF), KGF receptor, and fibroblast growth factor (FGF) receptor-2 were produced in primary cultures of human corneal
A C Castilho et al.
Molecular reproduction and development, 75(5), 940-945 (2008-01-01)
There is evidence that several fibroblast growth factors (FGFs) are involved in growth and development of the corpus luteum (CL), but many FGFs have not been investigated in this tissue, including FGF10. The objective of this study was to determine
R Reich-Slotky et al.
The Journal of biological chemistry, 270(50), 29813-29818 (1995-12-15)
Basic fibroblast growth factor (FGF) and keratinocyte growth factor (KGF) are structurally related fibroblast growth factors, yet they exhibit distinct receptor binding specificity. Basic FGF binds with high affinity to FGFR1, FGFR2, and FGFR4, whereas KGF does not interact with
F Ye et al.
Diabetologia, 48(2), 277-281 (2005-02-04)
The fibroblast growth factor (FGF) family consists of 22 members. In rodents, several FGFs are expressed in the pancreas, where they participate in epithelial-mesenchymal interactions. Our objective was to describe the pattern of expression of FGFs in the human embryonic
E Brogi et al.
The Journal of clinical investigation, 92(5), 2408-2418 (1993-11-01)
Because fibroblast growth factors (FGFs) modulate important functions of endothelial cells (EC) and smooth muscle cells (SMC), we studied FGF expression in human vascular cells and control or atherosclerotic arteries. All cells and arteries contained acidic (a) FGF and basic
Victor Schultz et al.
The Journal of biological chemistry, 292(6), 2495-2509 (2016-12-30)
A small library of well defined heparan sulfate (HS) polysaccharides was chemoenzymatically synthesized and used for a detailed structure-activity study of fibroblast growth factor (FGF) 1 and FGF2 signaling through FGF receptor (FGFR) 1c. The HS polysaccharide tested contained both
Honami Teramoto et al.
Journal of pediatric surgery, 38(7), 1021-1024 (2003-07-16)
Newborns with congenital diaphragmatic hernia (CDH) still have a high mortality rate, which has been attributed to pulmonary hypoplasia and pulmonary hypertension. Fibroblast growth factors (FGFs) are essential components of the gene network that regulates lung development. Recent studies suggest
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