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Showing 1-30 of 2074 results for "G7021" within Papers
Mio Okada et al.
Journal of breath research, 8(4), 046004-046004 (2014-11-02)
Transplantation of insulin (INS)-secreting cells differentiated in vitro from stem cells promises a safer and easier treatment of severe diabetes mellitus. A volatile bioactive compound, hydrogen sulfide (H2S), promotes cell differentiation; human tooth-pulp stem cells undergo hepatic differentiation. The aim
Audrey Beaussart et al.
Nanoscale, 7(36), 14996-15004 (2015-08-27)
Many fungal pathogens produce cell surface polysaccharides that play essential roles in host-pathogen interactions. In Aspergillus fumigatus, the newly discovered polysaccharide galactosaminogalactan (GAG) mediates adherence to a variety of substrates through molecular mechanisms that are poorly understood. Here we use
P A Adhikari et al.
Journal of animal science, 93(1), 209-216 (2015-01-09)
The aim was to determine the true total tract digestibility (TTTD) and standardized total tract digestibility (STTD) of P in canola meals from Brassica napus black (BNB) and Brassica juncea yellow (BJY) fed to growing pigs. Fifty-four barrows with an
Yi-Chun Chen et al.
Diabetologia, 57(10), 2066-2075 (2014-07-06)
EGF and gastrin co-administration reverses type 1 diabetes in rodent models. However, the failure of this to translate into a clinical treatment suggests that EGF-mediated tissue repair is a complicated process and warrants further investigation. Thus, we aimed to determine
C Ekman et al.
Journal of applied physiology (Bethesda, Md. : 1985), 119(9), 953-960 (2015-09-05)
Healthy first-degree relatives with heredity of type 2 diabetes (FH+) are known to have metabolic inflexibility compared with subjects without heredity for diabetes (FH-). In this study, we aimed to test the hypothesis that FH+ individuals have an impaired response
N V Batista et al.
Clinical and experimental immunology, 178(3), 416-427 (2014-08-13)
The prevalence of food allergy is rising in the western world. Allergen restriction is the chosen treatment in this condition, but continuous ingestion of the antigen has shown positive results in clinical trials. In a previous study, we have shown
Shefeeq M Theparambil et al.
Glia, 63(9), 1581-1594 (2015-03-31)
Cytosolic H(+) buffering plays a major role for shaping intracellular H(+) shifts and hence for the availability of H(+) for biochemical reactions and acid/base-coupled transport processes. H(+) buffering is one of the prime means to protect the cell from large
Sujatha Kandasamy et al.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 46(3), 659-666 (2015-09-29)
Ten bacterial strains that utilize cyanide (CN) as a nitrogen source were isolated from cassava factory wastewater after enrichment in a liquid media containing sodium cyanide (1 mM) and glucose (0.2% w/v). The strains could tolerate and grow in cyanide
V A Gault et al.
Acta diabetologica, 52(3), 461-471 (2014-11-07)
Xenin-25 is co-secreted with glucose-dependent insulinotropic polypeptide (GIP) from intestinal K-cells following a meal. Xenin-25 is believed to play a key role in glucose homoeostasis and potentiate the insulinotropic effect of GIP. This study investigated the effects of sub-chronic administration
Natasha R Ryz et al.
American journal of physiology. Gastrointestinal and liver physiology, 309(9), G730-G742 (2015-09-05)
Vitamin D deficiency affects more that 1 billion people worldwide. Although thought to increase risk of bacterial infections, the importance of vitamin D on host defense against intestinal bacterial pathogens is currently unclear since injection of the active form of
Rebeca Garcia et al.
Talanta, 147, 307-314 (2015-11-26)
Following bread dough development can be a hard task as no reliable method exists to give the optimal mixing time. Dough development is linked to the evolution of gluten proteins, carbohydrates and lipids which can result in modifications in the
Tae-Jin Ju et al.
Journal of pharmacological sciences, 126(2), 115-125 (2014-10-25)
The present study examined whether hemin could prevent the development of high-fat diet-induced insulin resistance in the liver and skeletal muscle using a hyperinsulinemic-euglycemic clamp. A four-week high-fat feeding to mice increased the body weight, fat mass, and plasma levels
Julia Kennedy-Darling et al.
Journal of proteome research, 13(8), 3810-3825 (2014-07-08)
DNA-protein interactions play critical roles in the control of genome expression and other fundamental processes. An essential element in understanding how these systems function is to identify their molecular components. We present here a novel strategy, Hybridization Capture of Chromatin
Zhongqi Fan et al.
BioMed research international, 2015, 960357-960357 (2015-03-31)
The microbial cell wall plays a crucial role in biofilm formation and drug resistance. cspA encodes a repeat-rich glycophosphatidylinositol-anchored cell wall protein in the pathogenic fungus Aspergillus fumigatus. To determine whether cspA has a significant impact on biofilm development and
Sally Yu Shi et al.
Nature communications, 6, 7415-7415 (2015-06-17)
Reactive oxygen species (ROS) have been linked to a wide variety of pathologies, including obesity and diabetes, but ROS also act as endogenous signalling molecules, regulating numerous biological processes. DJ-1 is one of the most evolutionarily conserved proteins across species
Alison Ludzki et al.
Diabetes, 64(8), 2769-2779 (2015-04-08)
Mitochondrial ADP transport may represent a convergence point unifying two prominent working models for the development of insulin resistance, as reactive lipids (specifically palmitoyl-CoA [P-CoA]) can inhibit ADP transport and subsequently increase mitochondrial reactive oxygen species emissions. In the current
Jian Li et al.
Bioprocess and biosystems engineering, 38(9), 1795-1802 (2015-05-28)
Biochemical production processes require water and nutrient resources for culture media preparation, but aqueous waste is generated after the target products are extracted. In this study, culture waste (including cells) produced from a lab-scale fermenter was fed into a microbial
Jiho Kang et al.
Journal of periodontal & implant science, 45(3), 101-110 (2015-07-02)
Sclerostin, an inhibitor of Wnt/β-catenin signaling, exerts negative effects on bone formation and contributes to periodontitis-induced alveolar bone loss. Recent studies have demonstrated that serum sclerostin levels are increased in diabetic patients and that sclerostin expression in alveolar bone is
Rebekka Kohlmann et al.
International journal of medical microbiology : IJMM, 305(4-5), 469-479 (2015-05-09)
Rapid identification of the causative microorganism is a key element in appropriate antimicrobial therapy of bloodstream infections. Whereas traditional analysis of positive blood cultures requires subculture over at least 16-24h prior to pathogen identification by, e.g. matrix-assisted laser-desorption/ionization time-of-flight mass
Yu-Feng Zhang et al.
Clinical laboratory, 61(8), 999-1008 (2015-10-03)
Advanced glycation end products (AGEs) accumulate in the retinal vascular cells, neurons, and glias of patients with diabetes mellitus and lead to the pathogenesis of diabetic retinopathy (DR). In the present study, to elucidate the orchestrated interactions of high mobility
Jason M Tonne et al.
Diabetologia, 58(2), 313-323 (2014-10-24)
Achieving a better understanding of beta cell regeneration after immunological destruction is crucial for the development of immunotherapy approaches for type 1 diabetes. In previous type 1 diabetes models, sustained immune activation eliminates regenerating beta cells, thus limiting the study
Investigating the antifungal activity and mechanism(s) of geraniol against Candida albicans strains.
Maria Clerya Alvino Leite et al.
Medical mycology, 53(3), 275-284 (2014-12-07)
Candida albicans can be a yeast that is a commensal on the human body but can cause opportunistic or pathogenic infections. Candida infections may create serious health problems and as a result has initiated a search for new drugs with
Saidan Ding et al.
The international journal of biochemistry & cell biology, 55, 252-263 (2014-09-16)
We previously demonstrated that dopamine (DA) overload may be a key mechanism behind development of minimal hepatic encephalopathy (MHE) in rats. It has been shown that low-grade cerebral oedema and oxidative stress play important roles in the pathogenesis of MHE.
Christophe Varin et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(27), 9900-9911 (2015-07-15)
Sleep-active neurons located in the ventrolateral preoptic nucleus (VLPO) play a crucial role in the induction and maintenance of slow-wave sleep (SWS). However, the cellular and molecular mechanisms responsible for their activation at sleep onset remain poorly understood. Here, we
Vinpocetine attenuates neointimal hyperplasia in diabetic rat carotid arteries after balloon injury.
Ke Wang et al.
PloS one, 9(5), e96894-e96894 (2014-05-14)
Diabetes exacerbates abnormal vascular smooth muscle cell (VSMC) accumulation in response to arterial wall injury. Vinpocetine has been shown to improve vascular remolding; however, little is known about the direct effects of vinpocetine on vascular complications mediated by diabetes. The
Marilyn G Wiebe et al.
Applied microbiology and biotechnology, 99(22), 9439-9447 (2015-08-13)
An open reading frame CC1225 from the Caulobacter crescentus CB15 genome sequence belongs to the Gfo/Idh/MocA protein family and has 47 % amino acid sequence identity with the glucose-fructose oxidoreductase from Zymomonas mobilis (Zm GFOR). We expressed the ORF CC1225
Notch signaling maintains T cell memories.
Aaron M Miller et al.
Nature medicine, 21(1), 16-18 (2015-01-09)
Edgar Dantán-González et al.
BMC veterinary research, 11, 278-278 (2015-11-11)
Avian coccidiosis is a disease caused worldwide by several species of parasite Eimeria that causes significant economic losses. This disease affects chickens development and production, that most of times is controlled with anticoccidial drugs. Although efforts have been made to
Olga N Karpus et al.
Arthritis research & therapy, 17, 6-6 (2015-01-19)
CD55, a glycosylphosphatidylinositol-anchored, complement-regulating protein (decay-accelerating factor), is expressed by fibroblast-like synoviocytes (FLS) with high local abundance in the intimal lining layer. We here explored the basis and consequences of this uncommon presence. Synovial tissue, primary FLS cultures, and three-dimensional
M Montazerozohori et al.
Materials science & engineering. C, Materials for biological applications, 55, 462-470 (2015-06-29)
Some new cadmium(II) Schiff base complexes CdLX2 (where X=Cl(-), Br(-), I(-), SCN(-) and N3(-) and L=N,N-bis((E)-3-(4-(dimethylamino)phenyl)allylidene)benzene-1,2-diamine) were synthesized and characterized by elemental analysis, FT-IR, UV-visible, (1)HNMR spectra, and conductivity measurements. Moreover, the structure of the CdLI2 was determined by single
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