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Showing 1-30 of 34 results for "GRSA" within Papers
Hye-Jin Eom et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 222, 125-134 (2019-05-06)
Sea-Nine™ 211 is an emerging biocide that has an adverse impact on aquatic environments. In this study, the marine polychaete Perinereis aibuhitensis was exposed to Sea-Nine (0.1, 1, and 10 μg L-1), and acute toxicity and biochemical responses such as changes in
A comparative cytotoxicity study of TiO 2 nanoparticles under light and dark conditions at low exposure concentrations
Dalai S, et al.
Toxicology Research, 1(2), 116-130 (2012)
Mostafa I Waly et al.
Asian Pacific journal of cancer prevention : APJCP, 13(8), 4051-4055 (2012-10-27)
Functional foods include antioxidant nutrients which may protect against many human chronic diseases by combating reactive oxygen species (ROS) generation. The purpose of the present study was to investigate the protective effect of pomegranate peel extract (PPE) on azoxymethane (AOM)-induced
Karl W Engel et al.
Journal of biophotonics, 9(11-12), 1148-1156 (2016-07-09)
Photobiomodulation (PBM) therapy has been noted to promote cell proliferation and growth in many different cell types shown both in vitro and in vivo. Currently, treatment regimens are used in the clinic for a variety of ailments, including wound healing.
Fazal Khan et al.
BMC complementary and alternative medicine, 17(1), 418-418 (2017-08-24)
Hepatocellular carcinoma (HCC) accounts for major cancer-related deaths despite current advanced therapies. Treatment and prognosis of HCC is better in patients with preserved liver function. Many natural products including ajwa dates (Phoenix dactylifera L.), are claimed to have hepatoprotective and
Jin Wuk Lee et al.
Aquatic toxicology (Amsterdam, Netherlands), 172, 67-79 (2016-01-17)
To examine the toxic effects of multi-walled carbon nanotubes (MWCNTs) in the marine environment, we first exposed the monogonont rotifer (Brachionus koreanus) to MWCNTs in the presence of copper. The acute toxicity of copper decreased significantly with a decrease in
Gurdeep Marwarha et al.
Journal of Alzheimer's disease : JAD, 68(1), 219-237 (2019-02-05)
Epidemiological studies have suggested a positive correlation between saturated fat intake and the risk for developing Alzheimer's disease (AD). While diets-enriched in the saturated free fatty acid (sFFA) palmitate has been shown to induce cognitive dysfunction and AD-like pathology, polyunsaturated
Yun Kyung Shin et al.
Harmful algae, 86, 37-45 (2019-07-31)
The ichthyotoxic Cochlodinium polykrikoides is one of the most harmful bloom-forming dinoflagellates. In the present study, the economically important red seabream Pagrus major was exposed to sublethal concentrations of C. polykrikoides (i.e., 1,000 and 3,000 cells mL-1) for 24 h, and
Md Niamul Haque et al.
PloS one, 14(4), e0214236-e0214236 (2019-04-10)
Chlorothalonil is a thiol-reactive antifoulant that disperses widely and has been found in the marine environment. However, there is limited information on the deleterious effects of chlorothalonil in marine mollusks. In this study, we evaluated the effects of chlorothalonil on
Imran Khan et al.
Scientific reports, 5, 10581-10581 (2015-06-02)
High power lasers are used extensively in medicine while lower power applications are popular for optical imaging, optogenetics, skin rejuvenation and a therapeutic modality termed photobiomodulation (PBM). This study addresses the therapeutic dose limits, biological safety and molecular pathway of
Deepak Kumar et al.
Environmental toxicology, 32(5), 1617-1627 (2017-01-20)
The present study deals with the toxicity assessment of two differently synthesized zero valent iron nanoparticles (nZVI, chemical and biological) as well as Fe
Toxicity effects of an environmental realistic herbicide mixture on the seagrass Zostera noltei
Diepens NJ, et al.
Environmental Pollution (Barking, Essex : 1987), 222, 393-403 (2017)
Michael F Almeida et al.
Journal of sports sciences, 36(12), 1363-1370 (2017-09-13)
Moderate physical exercise acts at molecular and behavioural levels, such as interfering in neuroplasticity, cell death, neurogenesis, cognition and motor functions. Therefore, the aim of this study is to analyse the cellular effects of moderate treadmill running upon substantia nigra
Effects of antifouling biocides on molecular and biochemical defense system in the gill of the pacific oyster Crassostrea gigas
Mi Seon P, et al.
PLoS ONE, 11(12), e0168978-e0168978 (2016)
V M Factor et al.
The Journal of biological chemistry, 273(25), 15846-15853 (1998-06-23)
In previous studies we have demonstrated that transforming growth factor (TGF)-alpha/c-myc double transgenic mice exhibit an enhanced rate of cell proliferation, accumulate extensive DNA damage, and develop multiple liver tumors between 4 and 8 months of age. To clarify the
Justin R Prigge et al.
Cell reports, 19(13), 2771-2781 (2017-06-29)
Energetic nutrients are oxidized to sustain high intracellular NADPH/NADP+ ratios. NADPH-dependent reduction of thioredoxin-1 (Trx1) disulfide and glutathione disulfide by thioredoxin reductase-1 (TrxR1) and glutathione reductase (Gsr), respectively, fuels antioxidant systems and deoxyribonucleotide synthesis. Mouse livers lacking both TrxR1 and
Mi Seon Park et al.
PloS one, 11(12), e0168978-e0168978 (2016-12-23)
Antifouling biocides such as organotin compounds and their alternatives are potent toxicants in marine ecosystems. In this study, we employed several molecular and biochemical response systems of the Pacific oyster Crassostrea gigas to understand a potential mode of action of
Kristin M O'Brien et al.
The Journal of experimental biology, 221(Pt 5) (2018-01-24)
The unusual pattern of expression of hemoglobin (Hb) and myoglobin (Mb) among Antarctic notothenioid fishes provides an exceptional model system for assessing the impact of these proteins on oxidative stress. We tested the hypothesis that the lack of oxygen-binding proteins
Brant L Kedrowski et al.
Journal of enzyme inhibition and medicinal chemistry, 29(4), 491-494 (2013-07-03)
The activity of glutathione reductase with an unnatural analog of oxidized glutathione was explored. The analog, L-γ-glutamyl-2-methyl-L-cysteinyl-glycine disulfide, places an additional methyl group on the alpha position of each of the central cysteine residues, which significantly increases steric bulk near
Eunjin Byeon et al.
Aquatic toxicology (Amsterdam, Netherlands), 218, 105337-105337 (2019-11-19)
To understand effects of two widely used antidepressant on the antioxidant defense mechanism in the marine rotifer Brachionus koreanus, we assessed acute toxicity and measured population growth, reactive oxygen species (ROS) levels, glutathione (GSH) levels, and antioxidant enzymatic activities (GST
Behnaz Ghaemi et al.
ACS applied materials & interfaces, 11(50), 46408-46418 (2019-11-16)
Recent studies suggest that cancer cell death accompanied by organelle dysfunction might be a promising approach for cancer therapy. The Golgi apparatus has a key role in cell function and may initiate signaling pathways to mitigate stress and, if irreparable
Glutathione: Chemical, Biochemical and Metabolic Aspects.
Dolphin D., et al.
Glutathione: Chemical, Biochemical and Metabolic Aspects (1989)
Comparative efficacy of three brands of gum acacia on adenine-induced chronic renal failure in rats.
B H Ali et al.
Physiological research, 62(1), 47-56 (2012-11-24)
Gum acacia (GA) is used in pharmaceutical, cosmetic and food industries as an emulsifier and stabilizer, and in some countries in the traditional treatment of patients with chronic kidney disease (CKD). We have previously found that GA ameliorates adenine-induced chronic
Hadja Fatima Tbahriti et al.
Biochemistry research international, 2013, 358985-358985 (2014-01-15)
Oxidative stress seems to be involved in the path physiology of cardiovascular complications of chronic kidney disease (CKD). In this study, we determined the effect of different stages of CKD and substitutive therapies on oxidative stress. One hundred sixty-seven patients
I K Smith et al.
Analytical biochemistry, 175(2), 408-413 (1988-12-01)
A method for assaying glutathione reductase (GSH; EC 1.6.4.2) in crude plant extracts is described. The method is based on the increase in absorbance at 412 nm when 5,5'-dithiobis(2-nitrobenzoic acid) (DTNB) is reduced by GSH. The effects of the following
Young Dae Kim et al.
Aquatic toxicology (Amsterdam, Netherlands), 188, 119-129 (2017-05-14)
Microcystins (MCs) are a major group of potent cyanobacterial toxins found in freshwater and even brackish waterbodies. To understand the putative correlation between bioconcentration of MCs and antioxidant responses of the digestive gland of bivalves, Pacific oyster Crassostrea gigas and
Grażyna Świderska-Kołacz et al.
Nutrients, 13(6) (2021-07-03)
Algae are potential and natural source of long-chain polyunsaturated fatty acids like eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). The diatom Pinnularia borealis accumulates high levels of EPA and may be considered as a source for commercial production of dietary
Hind A Alkhatabi et al.
Antioxidants (Basel, Switzerland), 11(3) (2022-03-26)
Venetoclax (ABT199) is a selective B-cell lymphoma 2 (BCL-2) inhibitor. The US FDA recently approved it to be used in combination with low-dose cytarabine or hypomethylating agents in acute myeloid leukemia (AML) or elderly patients non-eligible for chemotherapy. However, acquiring
Aida Begic et al.
Journal of enzyme inhibition and medicinal chemistry, 32(1), 478-489 (2017-01-20)
Examination of cadmium (Cd) toxicity and disulfiram (DSF) effect on liver was focused on oxidative stress (OS), bioelements status, morphological and functional changes. Male Wistar rats were intraperitoneally treated with 1 mg CdCl
Karla P Melo et al.
Neurotoxicity research, 35(2), 410-420 (2018-10-03)
Proteostasis and oxidative stress were evaluated in motor cortex and spinal cord of aged Lewis rats exposed to 1 mg/kg/day of rotenone during 4 or 8 weeks, prior or after practicing three protocols of mild treadmill running. Results demonstrated that exercise done
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