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Showing 1-6 of 6 results for "HPA018790" within Papers
Simone C Tauber et al.
Journal of neuropathology and experimental neurology, 73(1), 2-13 (2013-12-18)
Fas-apoptotic inhibitory molecule 2 (Faim2) is a neuron-specific membrane protein and a member of the evolutionary conserved lifeguard apoptosis regulatory gene family. Its neuroprotective effect in acute neurological diseases has been demonstrated in an in vivo model of focal cerebral
Tatiana Hurtado de Mendoza et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(41), 17189-17194 (2011-10-01)
Lifeguard (LFG) is an inhibitor of Fas-mediated cell death and is highly expressed in the cerebellum. We investigated the biological role of LFG in the cerebellum in vivo, using mice with reduced LFG expression generated by shRNA lentiviral transgenesis (shLFG
Vesna Bucan et al.
Cellular & molecular biology letters, 15(2), 296-310 (2010-03-26)
Lifeguard (LFG) is an anti-apoptotic protein that inhibits Fas-mediated death in tumour cells. However, the molecular function of human LFG in the carcinogenesis of human breast cells is uncertain. We studied the expression and function of endogenous LFG in four
Miriam Fernández et al.
Journal of neurochemistry, 103(1), 190-203 (2007-07-20)
Fas ligand (FasL)-receptor system plays an essential role in regulating cell death in the developing nervous system, and it has been implicated in neurodegenerative and inflammatory responses in the CNS. Lifeguard (LFG) is a protein highly expressed in the hippocampus
Daniel Komnig et al.
Journal of neurochemistry, 145(3), 258-270 (2018-01-10)
Delayed cell death in the penumbra region of acute ischemic stroke occurs through apoptotic mechanisms, making it amenable to therapeutic interventions. Fas/CD95 mediates apoptotic cell death in response to external stimuli. In mature neurons, Fas/CD95 signaling is modulated by Fas-apoptotic
Linlin Tang et al.
Diagnostic pathology, 9, 56-56 (2014-03-14)
The goal of our study is to investigate the associations between 18 candidate genetic markers and overweight/obesity. A total of 72 eligible articles were retrieved from literature databases including PubMed, Embase, SpingerLink, Web of Science, Chinese National Knowledge Infrastructure (CNKI)
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