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Showing 1-13 of 13 results for "HT110332" within Papers
Mi Rim Lee et al.
Experimental and therapeutic medicine, 17(3), 2185-2193 (2019-03-15)
The therapeutic effects of mulberry (Morus alba) leaves on lipid metabolism, including lipogenesis, lipolysis and hyperlipidemia are widely known, although their fermented products are yet to be applied. To investigate the therapeutic effects of a novel extract of mulberry leaves
Su Ji Bae et al.
Molecules (Basel, Switzerland), 25(11) (2020-06-12)
Perilla oil has been considered to have excellent potential for treating various diseases due to its contents of beneficial fatty acids, such as α-linolenic acid, oleic acid and linoleic acid. The therapeutic effects and molecular mechanism of an α-linolenic acid-enriched
Kristin Gee et al.
Tissue engineering. Part A, 26(7-8), 411-418 (2019-11-08)
Introduction: Splenectomy is common after trauma or hematologic disease, and alters immune protection against pathogens, which may lead to
Holger Greschik et al.
Cell death & disease, 8(11), e3173-e3173 (2017-11-24)
While several studies correlated increased expression of the histone code reader Spin1 with tumor formation or growth, little is known about physiological functions of the protein. We generated Spin1M5 mice with ablation of Spin1 in myoblast precursors using the Myf5-Cre
Hyeon Jun Choi et al.
Molecules (Basel, Switzerland), 25(4) (2020-02-27)
Positive physiological benefits of several plant oils on the UV-induced photoaging have been reported in some cell lines and model mice, but perilla oil collected from the seeds of PerillafrutescensL. has not been investigated in this context. To study the
Hyun-Jung Park et al.
Development (Cambridge, England), 144(12), 2282-2293 (2017-05-17)
In humans and rodents, the prostate gland develops from the embryonic urogenital sinus (UGS). The androgen receptor (AR) is thought to control the expression of morphogenetic genes in inductive UGS mesenchyme, which promotes proliferation and cytodifferentiation of the prostatic epithelium.
Hadir Marei et al.
Nature communications, 7, 10664-10664 (2016-02-19)
The small GTPase Rac1 has been implicated in the formation and dissemination of tumours. Upon activation by guanine nucleotide exchange factors (GEFs), Rac1 associates with a variety of proteins in the cell thereby regulating various functions, including cell migration. However
Christy L Trejo et al.
PloS one, 14(2), e0212031-e0212031 (2019-02-23)
We describe the use of a ligation-based targeted whole transcriptome expression profiling assay, TempO-Seq, to profile formalin-fixed paraffin-embedded (FFPE) tissue, including H&E stained FFPE tissue, by directly lysing tissue scraped from slides without extracting RNA or converting the RNA to
Jorge A Pereira et al.
Human molecular genetics, 29(8), 1253-1273 (2020-03-05)
Some mutations affecting dynamin 2 (DNM2) can cause dominantly inherited Charcot-Marie-Tooth (CMT) neuropathy. Here, we describe the analysis of mice carrying the DNM2 K562E mutation which has been associated with dominant-intermediate CMT type B (CMTDIB). Contrary to our expectations, heterozygous
Insu Kwon et al.
The journal of physiological sciences : JPS, 68(3), 269-280 (2017-02-19)
Elevation of anabolism and concurrent suppression of catabolism are critical metabolic adaptations for muscular hypertrophy in response to resistance exercise (RE). Here, we investigated if RE-induced muscular hypertrophy is acquired by modulating a critical catabolic process autophagy. Male Wistar Hannover
Thyroid hormone availability in the human fetal brain: novel entry pathways and role of radial glia.
Daniela López-Espíndola et al.
Brain structure & function, 224(6), 2103-2119 (2019-06-06)
Thyroid hormones (TH) are crucial for brain development; their deficiency during neurodevelopment impairs neural cell differentiation and causes irreversible neurological alterations. Understanding TH action, and in particular the mechanisms regulating TH availability in the prenatal human brain is essential to
Yael Aylon et al.
Genes & development, 30(7), 786-797 (2016-03-26)
The Hippo signaling pathway is a major regulator of organ size. In the liver, Hippo pathway deregulation promotes hyperplasia and hepatocellular carcinoma primarily through hyperactivation of its downstream effector, YAP. The LATS2 tumor suppressor is a core member of the
Chun-Wei Allen Feng et al.
Scientific reports, 7(1), 17619-17619 (2017-12-17)
Male infertility is a major and growing problem and, in most cases, the specific root cause is unknown. Here we show that the transcription factor SOX30 plays a critical role in mouse spermatogenesis. Sox30-null mice are healthy and females are
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