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Showing 1-19 of 19 results for "L4386" within Papers
Rajesh Guruswamy Damodaran et al.
Biotechnology progress, 34(4), 1059-1068 (2018-04-01)
Type II diabetes progresses with inadequate insulin secretion and prolonged elevated circulating glucose levels. Also, pancreatic islets isolated for transplantation or tissue engineering can be exposed to glucose over extended timeframe. We hypothesized that isolated pancreatic islets can secrete insulin
Sarah Johann et al.
Toxics, 8(2) (2020-07-02)
Genotoxicity assessment is of high relevance for crude and refined petroleum products, since oil compounds are known to cause DNA damage with severe consequences for aquatic biota as demonstrated in long-term monitoring studies. This study aimed at the optimization and
Rajesh Guruswamy Damodaran et al.
Journal of tissue engineering and regenerative medicine, 12(5), 1230-1237 (2018-03-03)
Diabetes mellitus involves the loss of function and/or absolute numbers of insulin-producing β cells in pancreatic islets. Islet transplantation is currently being investigated as a potential cure, and advances in tissue engineering methods can be used to improve pancreatic islets
Emilio E Méndez-Olivos et al.
Frontiers in cellular neuroscience, 11, 398-398 (2018-01-13)
Mammals are unable to regenerate its spinal cord after a lesion, meanwhile, anuran amphibians are capable of spinal cord regeneration only as larvae, and during metamorphosis, this capability is lost. Sox2/3+ cells present in the spinal cord of regenerative larvae
Liwen Wang et al.
Autophagy, 14(3), 518-533 (2017-12-08)
Melanoma is among the most life-threatening cancers. The pathogenesis of melanoma has not been fully elucidated. Recently, dysregulated macroautophagy/autophagy has been found to play a critical but inconsistent role in modulating melanoma growth at different stages, with the regulatory mechanism
Lianchun Fan et al.
Stem cells and development, 17(3), 585-597 (2008-06-26)
Although embryonic germ (EG) cell-mediated gene transfer has been successful in the mouse for more than a decade, this approach is limited in other species due to the difficulty of isolating the small numbers of progenitors of germ cell lineage
Christiano Calixto Conceição et al.
Scientific reports, 11(1), 19202-19202 (2021-09-30)
In the present work, we established two novel embryonic cell lines from the mosquito Aedes fluviatilis containing or not the naturally occurring symbiont bacteria Wolbachia, which were called wAflu1 and Aflu2, respectively. We also obtained wAflu1 without Wolbachia after tetracycline
Zora Chui-Kuen Chan et al.
eLife, 9 (2020-03-26)
At vertebrate neuromuscular junctions (NMJs), the synaptic basal lamina contains different extracellular matrix (ECM) proteins and synaptogenic factors that induce and maintain synaptic specializations. Here, we report that podosome-like structures (PLSs) induced by ubiquitous ECM proteins regulate the formation and
Steven J Conrad et al.
Avian diseases, 64(3), 243-246 (2020-11-19)
Marek's disease (MD) is an oncogenic, lymphoproliferative, and highly contagious disease of chickens. Its etiologic agent is the alphaherpesvirus Marek's disease virus (MDV, Gallid alphaherpesvirus 2), and it is a chronic and ubiquitous problem for the poultry industry with significant
Y Qian et al.
Insect biochemistry and molecular biology, 27(5), 387-395 (1997-05-01)
Prostaglandins of the 2-series (e.g. PGE2) are typically synthesized from arachidonic acid (AA) after AA is released from cellular phospholipids after activation of an intracellular phospholipase A2 (PLA2). Treatment of isolated salivary glands with PLA2 inhibitor oleyloxyethyl phosphorylcholine (OPC) or
Kento Igarashi et al.
PloS one, 12(1), e0170006-e0170006 (2017-01-21)
Nbs1 is one of the genes responsible for Nijmegen breakage syndrome, which is marked with high radiosensitivity. In human NBS1 (hNBS1), Q185E polymorphism is known as the factor to cancer risks, although its DSB repair defect has not been addressed.
N Garcia-Velasco et al.
Ecotoxicology and environmental safety, 183, 109545-109545 (2019-08-26)
Earthworm immune cells (coelomocytes) have become a target system in ecotoxicology due to their sensitivity against a wide range of pollutants, including silver nanoparticles (AgNPs). Presently, in vitro approaches (viability assays in microplate, flow cytometry, cell sorting) with primary cultures
Roger Maldonado-Ruiz et al.
Nutrients, 11(6) (2019-06-05)
Maternal overnutrition during pregnancy leads to metabolic alterations, including obesity, hyperphagia, and inflammation in the offspring. Nutritional priming of central inflammation and its role in ghrelin sensitivity during fed and fasted states have not been analyzed. The current study aims
Xinxin Wu et al.
Plant & cell physiology, 55(8), 1426-1436 (2014-05-23)
The secretion of organic acid anions from roots is an important mechanism for plant aluminum (Al) tolerance. Here we report cloning and characterizing BoMATE (KF031944), a multidrug and toxic compound extrusion (MATE) family gene from cabbage (Brassica oleracea). The expression
Ferda Topal Celikkan et al.
Cytotherapy, 21(1), 64-75 (2018-11-21)
The HUC-HEART Trial is a clinical study of intramyocardial delivery of current Good Manufacturing Practice (cGMP)-grade human umbilical cord multipotent stromal cells (HUC-MSCs) in ischemic cardiomyopathy where 2 × 107 cells are administered to peri-infarcted myocardium. Prior to the onset of the trial
Joshua Phelan et al.
Talanta, 211, 120737-120737 (2020-02-20)
This is the first demonstration of the study of glycan protein turnover in living cells by FTIR with commercially available tetraacetylated N-Azidoacetyl-D-Mannosamine (Ac4ManNAz) label. The FTIR analysis has shown to be able to monitor the metabolism of glycans in living
Bernardo Saucedo et al.
Scientific reports, 9(1), 4453-4453 (2019-03-16)
Ranavirus is the second most common infectious cause of amphibian mortality. These viruses affect caudates, an order in which information regarding Ranavirus pathogenesis is scarce. In the Netherlands, two strains (CMTV-NL I and III) were suspected to possess distinct pathogenicity
Nancy Nader et al.
PLoS biology, 18(11), e3000901-e3000901 (2020-11-03)
The steroid hormone progesterone (P4) mediates many physiological processes through either nuclear receptors that modulate gene expression or membrane P4 receptors (mPRs) that mediate nongenomic signaling. mPR signaling remains poorly understood. Here we show that the topology of mPRβ is
Effect of estradiol on vitellogenesis and oocyte development of female swimming crab, Portunus trituberculatus
Liu M, et al.
Aquaculture (Amsterdam, Netherlands), 486, 240-245 (2018)
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