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Showing 1-30 of 34 results for "M1787" within Papers
A K Conly et al.
Poultry science, 91(7), 1633-1640 (2012-06-16)
These studies were designed to determine the relative bioavailability and tolerance of tribasic Mn chloride (TBMC) for growing broiler chickens. In experiment 1, birds were fed a basal diet (starter, 102 ppm; grower, 209 ppm) or the basal diet supplemented
In vitro Assessment of RNA Polymerase I Activity
Govoni M
Oncogene (2016)
Michele Michelin et al.
World journal of microbiology & biotechnology, 28(11), 3179-3186 (2012-07-26)
Aspergillus ochraceus, a thermotolerant fungus isolated in Brazil from decomposing materials, produced an extracellular β-xylosidase that was purified using DEAE-cellulose ion exchange chromatography, Sephadex G-100 and Biogel P-60 gel filtration. β-xylosidase is a glycoprotein (39 % carbohydrate content) and has
Oliviero L Gobbo et al.
Contrast media & molecular imaging, 7(6), 542-546 (2012-09-20)
Lung parenchyma remains one of the most difficult tissues to be imaged by means of magnetic resonance imaging (MRI). Several MRI techniques are routinely used for lung imaging. However, manganese-enhancement MRI (MEMRI) technique has not been associated with pulmonary MRI.
Adrienne P Stephenson et al.
Toxicology letters, 218(3), 299-307 (2013-01-09)
Manganese (Mn) is an essential trace element required for normal function and development. However, exposure to this metal at elevated levels may cause manganism, a progressive neurodegenerative disorder with neurological symptoms similar to idiopathic Parkinson's disease (IPD). Elevated body burdens
Tora Sund Morken et al.
Pediatric research, 73(2), 171-179 (2012-11-24)
Hypoxia-ischemia (HI) induces delayed inflammation and long-term gray and white matter brain injury that may be altered by hyperoxia. HI and 2 h of hyperoxia (100% O2) or room air (21% O2) in 7-d-old (P7) rats were studied by magnetic resonance
Elizabeth Greally et al.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 15, 4-4 (2013-01-18)
Manganese-enhanced cardiovascular magnetic resonance (MECMR) can non-invasively assess myocardial calcium influx, and calcium levels are known to be elevated in muscular dystrophy cardiomyopathy based on cellular studies. Left ventricular functional studies and MECMR were performed in mdx mice (model of
Kamilla Blecharz-Klin et al.
Toxicology and applied pharmacology, 265(1), 1-9 (2012-10-02)
The effect of intranasal manganese chloride (MnCl(2)·4H(2)O) exposure on spatial learning, memory and motor activity was estimated in Morris water maze task in adult rats. Three-month-old male Wistar rats received for 2weeks MnCl(2)·4H(2)O at two doses the following: 0.2mg/kg b.w.
M R Sepúlveda et al.
Contrast media & molecular imaging, 7(4), 426-434 (2012-06-01)
Manganese is a vital element and cofactor of many key enzymes, but it is toxic at high levels, causing pronounced disturbances in the mammalian brain. Magnetic resonance imaging (MRI) studies using manganese ions as a paramagnetic contrast agent are often
Asad A Aboud et al.
Neurotoxicology, 33(6), 1443-1449 (2012-10-27)
Manganese (Mn) is an environmental risk factor for Parkinson's disease (PD). Recessive inheritance of PARK2 mutations is strongly associated with early onset PD (EOPD). It is widely assumed that the influence of PD environmental risk factors may be enhanced by
Xiao-fei Liu et al.
Biological trace element research, 151(2), 217-224 (2012-11-30)
Manganese (Mn) is an essential element required for normal development and reproduction. However, little is known about the reproductive toxicity of Mn in birds. To investigate the Mn-induced toxicity on testicular trace element levels and crucial hormonal parameters on male
Manganese enhanced MRI in rat hippocampus: A correlative study with synchrotron X-ray microprobe
Daoust A, et al.
Neuroimage, 64, 10-18 (2013)
Jason P Covy et al.
Journal of neuroscience research, 90(12), 2306-2316 (2012-08-01)
Mutations in ATP13A2, which encodes a lysosomal P-type ATPase of unknown function, cause an autosomal recessive parkinsonian syndrome. With mammalian cells, we show that ATP13A2 expression protects against manganese and nickel toxicity, in addition to proteasomal, mitochondrial, and oxidative stress.
O M Vasyliv et al.
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993), 75(2), 37-44 (2013-06-01)
Superoxide dismutase, as one of the enzymes of cells' antioxidant defensive system, catalyzes superoxide anion-radical (O2-) dismutation with O2 and H2O2 forming. The influence of such transition metal compounds, as FeSO4, FeCl3, MnCl2, NiCl2, and CoCl2 on superoxide dismutase activity
Highly multiplexed and strand-specific single-cell RNA 5′ end sequencing
Islam S, et al.
Nature Protocols, 7(5), 813-813 (2012)
Dinamene Santos et al.
Biological trace element research, 152(1), 113-116 (2013-01-15)
Manganese (Mn) is an essential metal for biological systems; however, occupational or clinical exposure to high levels of Mn can produce a neurological disorder called manganism. Oxidative stress and neuroinflammation play major roles in the Mn-induced neurodegeneration leading to dysfunction
Dorit B Hoffmann et al.
Journal of neuropathology and experimental neurology, 72(8), 745-757 (2013-07-19)
Optic neuritis is a common manifestation of multiple sclerosis, an inflammatory demyelinating disease of the CNS. Recently, the neurodegenerative component of multiple sclerosis has come under focus particularly because permanent disability in patients correlates well with neurodegeneration; and observations in
Barry J Bowman et al.
Eukaryotic cell, 11(11), 1362-1370 (2012-09-18)
The pmr gene is predicted to encode a Ca(2+)-ATPase in the secretory pathway. We examined two strains of Neurospora crassa that lacked PMR: the Δpmr strain, in which pmr was completely deleted, and pmr(RIP), in which the gene was extensively
A G Kanthasamy et al.
Toxicology letters, 214(3), 288-295 (2012-09-22)
The role of normal cellular prion protein (PrP) remains to be fully elucidated; however, the protein is crucial for the infection and progression of prion diseases. Recent evidence indicates that PrP is a metalloprotein since the octapeptide repeat sequences in
Molecular Cloning: A Laboratory Manual
Sambrook, J. and Russel, D.W.
Molecular Cloning: A Laboratory Manual, 1, A4-A4 (2001)
Katharina A Sterenczak et al.
BMC cancer, 12, 284-284 (2012-07-13)
Cell lines represent a key tool in cancer research allowing the generation of neoplasias which resemble initial tumours in in-vivo animal models. The characterisation of early tumour development is of major interest in order to evaluate the efficacy of therapeutic
Geoffrey J Topping et al.
Medical physics, 40(4), 042502-042502 (2013-04-06)
Manganese(II) is employed as a contrast agent with magnetic resonance imaging (MRI) for study of neuronal activation in rats and mice. However, at the concentrations required for MRI, Mn may induce pharmacological or toxic effects. Positron emission tomography (PET) imaging
Anne Bertrand et al.
NeuroImage, 64, 693-702 (2012-09-11)
The impairment of axonal transport by overexpression or hyperphosphorylation of tau is well documented for in vitro conditions; however, only a few studies on this phenomenon have been conducted in vivo, using invasive procedures, and with contradictory results. Here we
Dinamene Santos et al.
Biological trace element research, 150(1-3), 337-341 (2012-09-14)
Manganese (Mn) is an essential element and it acts as a cofactor for a number of enzymatic reactions, including those involved in amino acid, lipid, protein, and carbohydrate metabolism. Excessive exposure to Mn can lead to poisoning, characterized by psychiatric
Marta Sidoryk-Wegrzynowicz et al.
Journal of neurochemistry, 122(4), 856-867 (2012-06-20)
Manganese (Mn) has been implicated in the impairment of the glutamate-glutamine cycling (GGC) by deregulation of Glu and glutamine (Gln) turnover in astrocytes. Here, we have examined possible mechanisms involved in the Mn(II)-mediated disruption of Glu turnover, including those related
Alexia Daoust et al.
NeuroImage, 96, 133-142 (2014-04-08)
The MAP6 (microtubule-associated protein 6) KO mouse is a microtubule-deficient model of schizophrenia that exhibits severe behavioral disorders that are associated with synaptic plasticity anomalies. These defects are alleviated not only by neuroleptics, which are the gold standard molecules for
Jerome A Roth et al.
Neurotoxicology, 35, 121-128 (2013-01-15)
Chronic exposure to Mn results in the development of a neurological disorder known as manganism characterized by neurological deficits resembling that seen in Parkinsonism. Although dopaminergic neurons within the nigrostriatal pathway appear intact, Mn-induced irregularities in DA transmission have been
Graziela Ribeiro Batista et al.
The European journal of esthetic dentistry : official journal of the European Academy of Esthetic Dentistry, 8(1), 104-117 (2013-02-08)
This study aimed to evaluate the efficacy of chemical agents to increase the bleaching effectiveness of 10% carbamide peroxide. Two hundred and ninety enamel-dentin discs were prepared from bovine incisors. The color measurement was performed by a spectrophotometer using the
Lisa Hoffman et al.
Environmental toxicology and pharmacology, 34(2), 556-573 (2012-07-25)
The effects of the fungicides Maneb, Mancozeb, and Zineb were investigated in transformed colon cells, HT-29, Caco2 and non-transformed cells, CCD-18Co. Significant decreases in viability were observed with Maneb and Mancozeb in HT-29 and CCD-18Co (80-260μM), and Caco2 cells (40-180μM).
Syndecan-1 regulates cell migration and fibronectin fibril assembly
Stepp MA, et al.
Experimental Cell Research, 316(14), 2322-2339 (2010)
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