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Showing 1-30 of 38 results for "M6699" within Papers
Eva Rufino-Palomares et al.
Proteomics, 11(16), 3312-3325 (2011-07-14)
Maslinic acid (MA) is a pentacyclic triterpene used as a feed additive to stimulate growth, protein-turnover rates, and hyperplasia in fish. To further our understanding of cellular mechanisms underlying the action of MA, we have used 2-DE coupled with MS
Jun Liu et al.
Natural product research, 25(12), 1190-1194 (2011-07-12)
In this study, we have examined the hypolipidemic effect of olive pomace extracts. Identification and quantitation of maslinic acid and oleanolic acid as the potentially effective components of the pomace extracts were carried out by high performance liquid chromatography methods.
M Gowri Ponnapalli et al.
Journal of natural products, 75(2), 275-279 (2012-02-10)
Four new isomeric macrolides of combretastatin D-2 congeners named isocorniculatolide A (1), 11-O-methylisocorniculatolide A (2), 11-O-methylcorniculatolide A (3), and 12-hydroxy-11-O-methylcorniculatolide A (4), and the known corniculatolide A (5), arjunolic acid, and maslinic acid were isolated from the CHCl(3) extract of
Yi-chih Hung et al.
Food & function, 6(9), 2967-2974 (2015-07-21)
The cardiac protective effects of asiatic acid (AA) and maslinic acid (MA) in diabetic mice were examined. These triterpenoids at 0.1 or 0.2% of the diet were supplied to diabetic mice for 12 weeks. The AA or MA treatments decreased
Hala I Al-Jaber et al.
Journal of Asian natural products research, 14(7), 618-625 (2012-05-12)
The novel seco-ursane-type triterpenoid 3β,11α-dihydroxy-17,22-seco-17(28), 12-ursadien-22-oic acid (1) was isolated for the first time from a natural source from two Salvia species growing wild in Jordan, Salvia palaestina Benth. and Salvia syrica L. In addition to compound 1, S. syriaca
Parth Thakor et al.
Journal of kidney cancer and VHL, 4(1), 16-24 (2017-04-14)
Despite the introduction of many novel therapeutics in clinical practice, metastatic renal cell carcinoma (RCC) remains a treatment-resistant cancer. As red and processed meat are considered risk factors for RCC, and a vegetable-rich diet is thought to reduce this risk
Susana Sánchez-Tena et al.
PloS one, 8(3), e59392-e59392 (2013-03-26)
Chemoprevention is a pragmatic approach to reduce the risk of colorectal cancer, one of the leading causes of cancer-related death in western countries. In this regard, maslinic acid (MA), a pentacyclic triterpene extracted from wax-like coatings of olives, is known
Yisong Qian et al.
European journal of pharmacology, 670(1), 148-153 (2011-08-16)
Maslinic acid is a triterpenoid compound present in plants of Olea europaea. This compound has been reported to have potent antioxidant, anti-cancer, anti-HIV and anti-inflammatory activities. In this study, we investigated the neuroprotective effect of maslinic acid and its mechanism
Andres Parra et al.
European journal of medicinal chemistry, 46(12), 5991-6001 (2011-10-25)
Maslinic acid (2α,3β-dihydroxyolean-12-en-28-oic acid), a natural dihydroxylated pentacyclic triterpene acid isolated from olive-pressing residues, has been investigated together with some of its derivatives regarding the induction of apoptosis in B16F10 melanoma cells. Some of the compounds tested are described in
Ana Márquez Martín et al.
Free radical research, 40(3), 295-302 (2006-02-18)
The pentacyclic triterpene maslinic acid (MA) is a natural compound present in the non glyceride fraction of pomace olive oil, also called orujo olive oil. This compound has previously demonstrated antioxidant properties against lipid peroxidation in vitro, but its effects
Tomohiro Nabekura et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 70, 140-145 (2015-03-18)
Drug efflux transporter P-glycoprotein plays an important role in cancer chemotherapy. The nuclear factor-κB (NF-κB) transcription factors play critical roles in development and progression of cancer. In this study, the effects of natural compounds that can inhibit NF-κB activation on
Glòria Lozano-Mena et al.
Journal of agricultural and food chemistry, 60(41), 10220-10225 (2012-09-26)
Maslinic acid, a pentacyclic triterpene from olives, has been reported to exert beneficial effects on health, including anticarcinogenic activity. Despite its importance, little is known about its bioavailability in both humans and animals. A fundamental step for this evaluation consisted
Su Yeong Kim et al.
Natural product communications, 9(12), 1683-1685 (2015-01-30)
The ethanol extract of Tilia taquetii Schneider leaves was investigated for its anti-wrinkle properties and for the relevant chemical constituents. Phytochemical studies led to the identification of five known compounds, viz. phytol (1), isoquercitrin (2), oleanderolide (3), arjunolic acid (4)
Ana Marquez-Martin et al.
Cytokine, 36(5-6), 211-217 (2007-02-13)
Olive pomace oil, also known as "orujo" olive oil, is a blend of refined-pomace oil and virgin olive oil, fit for human consumption. Maslinic acid, oleanolic acid, erythrodiol, and uvaol are pentacyclic triterpenes, found in the non-glyceride fraction of orujo
Carlos Moneriz et al.
Malaria journal, 10, 103-103 (2011-04-27)
The anti-malarial activity of maslinic acid (MA), a natural triterpene which has been previously shown to exert a parasitostatic action on Plasmodium falciparum cultures, was analysed in vivo by using the Plasmodium yoelii 17XL murine model. ICR mice were infected
Carlos Moneriz et al.
The FEBS journal, 278(16), 2951-2961 (2011-06-22)
Most drugs against malaria that are available or under development target a single process of the parasite infective cycle, favouring the appearance of resistant mutants which are easily spread in areas under chemotherapeutic treatments. Maslinic acid (MA) is a low
Fernando J Reyes-Zurita et al.
BMC cancer, 11, 154-154 (2011-04-29)
Maslinic acid, a pentacyclic triterpene found in the protective wax-like coating of the leaves and fruit of Olea europaea L., is a promising agent for the prevention of colon cancer. We have shown elsewhere that maslinic acid inhibits cell proliferation
Yan Sun et al.
Talanta, 205, 120011-120011 (2019-08-28)
A fast and simple analytical method was developed to fully understand the chemical diversity of pentacyclic triterpenes: lupane, oleanane and ursane type, using multiple neutral loss markers scanning combined with substructure recognition (MNLSR). This procedure was performed on ultra-high performance
Althaf Hussain Shaik et al.
Journal of medicinal food, 15(8), 741-746 (2012-08-01)
The present study aimed to evaluate the protective effect of maslinic acid (MA) on body weight, heart weight, lipids, lipoproteins, lipid peroxidation (LPO), cardiac marker enzymes, and paraoxonase (PON) in normal control and isoproterenol (ISO)-induced myocardial infarcted albino Wistar rats.
Carlos Moneriz et al.
Malaria journal, 10, 82-82 (2011-04-12)
Natural products have played an important role as leads for the development of new drugs against malaria. Recent studies have shown that maslinic acid (MA), a natural triterpene obtained from olive pomace, which displays multiple biological and antimicrobial activities, also
Longfei Huang et al.
European journal of pharmacology, 672(1-3), 169-174 (2011-10-06)
Maslinic acid (2-α, 3-β-dihydroxyolean-12-en-28-oic acid) is a natural triterpenoid compound from Olea europaea. This compound prevents oxidative stress and pro-inflammatory cytokine generation in vitro. This study was planned to investigate the anti-inflammatory effects of maslinic acid in central nervous system
W H Yap et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(2), 183-191 (2011-09-07)
Maslinic acid, a natural pentacyclic triterpene has been shown to inhibit growth and induce apoptosis in some tumour cell lines. We studied the molecular response of Raji cells towards maslinic acid treatment. A proteomics approach was employed to identify the
Estela Giménez et al.
Journal of chromatography. A, 1410, 68-75 (2015-07-27)
Pentacyclic triterpenes are gaining interest due to their beneficial health effects, as anti-inflammatory, anti-diabetic and anti-tumoral, among others. In this study, an analytical LC-MS method was developed for the simultaneous determination of maslinic, oleanolic and ursolic acids along with erythrodiol
Ivone Lucia Acebey-Castellon et al.
Journal of natural products, 74(2), 163-168 (2011-02-04)
Three new bidesmosidic saponins (1-3) and a new ursane triterpenoid, 2α,3β,11α,23-tetrahydroxyurs-12-en-28-oic acid (4), along with seven known compounds, were isolated from a methanolic extract of the leaves of Symplocos lancifolia. The bidesmosidic saponins were found to possess the same sugar
Vlasios Goulas et al.
Phytochemical analysis : PCA, 23(5), 444-449 (2012-01-04)
Triterpenic acids, such as maslinic acid and oleanolic acid, are commonly found in olive fruits and have been associated with many health benefits. The drying and extraction methods, as well as the solvents used, are critical factors in the determination
Dong-Mei Wu et al.
Naunyn-Schmiedeberg's archives of pharmacology, 383(3), 321-330 (2011-02-01)
Maslinic acid (MA) is a triterpenoid with a high concentration that exists in olives. This natural compound, which has shown multiple biological activities, was proved to be an anti-tumoral agent more recently. We have investigated the mechanisms of MA with
Teng Guan et al.
Journal of neuroscience research, 89(11), 1829-1839 (2011-07-30)
Maslinic acid (MA), a natural triterpene from Olea europaea L., is a well-known inhibitor of glycogen phosphorylase and elicits multiple biological activities. The purpose of this study was to evaluate the effects of MA on focal cerebral ischemia in hyperglycemic
Lim Yang Mooi et al.
Asian Pacific journal of cancer prevention : APJCP, 13(4), 1177-1182 (2012-07-18)
Protein kinase C (PKC) has been implicated in carcinogenesis and displays variable expression profiles during cancer progression. Studies of dietary phytochemicals on cancer signalling pathway regulation have been conducted to search for potent signalling regulatory agents. The present study was
Optimisation of microwave-assisted extraction of triterpenoic acids from olive mill waste using response surface methodology
Ozkan G, et al.,
Quality Assurance and Safety of Crops & Foods, 9(2), 179-185 (2017)
So Young Park et al.
The British journal of nutrition, 109(2), 210-222 (2012-06-22)
Maslinic acid is found in various natural sources, most notably in pomace olive oil, and exerts pro-apoptotic activities in various cancer cells in vitro. In the present study, DU145 human prostate cancer cells were cultured with 0-25 μm-maslinic acid to
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