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Showing 1-30 of 90 results for "M6752" within Papers
Claire E McKellar et al.
eLife, 9 (2020-06-26)
We describe the anatomy of all the primary motor neurons in the fly proboscis and characterize their contributions to its diverse reaching movements. Pairing this behavior with the wealth of Drosophila's genetic tools offers the possibility to study motor control
Yeun Kim et al.
Acta odontologica Scandinavica, 73(6), 427-432 (2014-11-12)
Micro-computed tomography (MCT) with alternative image reformatting techniques shows complex and detailed root canal anatomy. This study compared two-dimensional (2D) and 3D MCT image reformatting with standard tooth clearing for studying mandibular first molar mesial root canal morphology. Extracted human
Hongxia Wang et al.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 206(2), 289-307 (2020-01-07)
Voltage-gated sodium (NaV) channels, encoded by the gene para, play a critical role in the rapid processing and propagation of visual information related to collision avoidance behaviors. We investigated their localization by immunostaining the optic lobes and central brain of
ChengXiao Wang et al.
AAPS PharmSciTech, 13(2), 556-567 (2012-04-06)
We prepared pressure-sensitive adhesive (PSA) patches based on styrene-isoprene-styrene (SIS) thermoplastic elastomer using hot-melt coating method. The liquid paraffine is added in the PSA matrices as a plasticizer to moderate the PSA properties. Three drugs, methyl salicylate, capsaicin, and diphenhydramine
Wouter Kegge et al.
Annals of botany, 115(6), 961-970 (2015-04-09)
Volatile organic compounds (VOCs) play various roles in plant-plant interactions, and constitutively produced VOCs might act as a cue to sense neighbouring plants. Previous studies have shown that VOCs emitted from the barley (Hordeum vulgare) cultivar 'Alva' cause changes in
Colm Carraher et al.
PloS one, 7(6), e38391-e38391 (2012-06-16)
In insects, odorant receptors detect volatile cues involved in behaviours such as mate recognition, food location and oviposition. We have investigated the evolution of three odorant receptors from five species within the moth genera Ctenopseustis and Planotrotrix, family Tortricidae, which
Nicole A Marjon et al.
Molecular cancer research : MCR, 12(11), 1644-1654 (2014-07-18)
The role of 17β-estradiol (E2) in breast cancer development and tumor growth has traditionally been attributed exclusively to the activation of estrogen receptor-α (ERα). Although targeted inhibition of ERα is a successful approach for patients with ERα(+) breast cancer, many
Ticiano P Barbosa et al.
Bioorganic & medicinal chemistry, 19(14), 4250-4256 (2011-06-21)
The chalcone-like series 1a-1g was efficiently synthesized from Morita-Baylis-Hillman reaction (52-74% yields). Compounds 1a-1g were designed by molecular hybridization based on the anti-inflammatory drug methyl salicylate (3) and the antileishmanial moiety of the Morita-Baylis-Hillman adducts 2a-2g. The 1a-1g compounds were
Sandra L Grimm et al.
Molecular endocrinology (Baltimore, Md.), 28(12), 2025-2037 (2014-10-22)
Progesterone receptors (PRs) are phosphorylated on multiple sites, and a variety of roles for phosphorylation have been suggested by cell-based studies. Previous studies using PR-null mice have shown that PR plays an important role in female fertility, regulation of uterine
Taraka R Donti et al.
Disease models & mechanisms, 7(2), 271-280 (2013-11-26)
Mutations in subunits of succinyl-CoA synthetase/ligase (SCS), a component of the citric acid cycle, are associated with mitochondrial encephalomyopathy, elevation of methylmalonic acid (MMA), and mitochondrial DNA (mtDNA) depletion. A FACS-based retroviral-mediated gene trap mutagenesis screen in mouse embryonic stem
Niall J A Conboy et al.
Journal of chemical ecology, 46(11-12), 1090-1104 (2020-10-28)
The glasshouse whitefly (Trialeurodes vaporariorum Westwood) is a polyphagous arthropod pest that is of particular detriment to glasshouse grown tomato (Solanum lycopersicum) across temperate regions of the world. Control of whiteflies with synthetic pesticides has resulted in the evolution of
T Y Chan
Human & experimental toxicology, 15(9), 747-750 (1996-09-01)
Methyl salicylate (oil of wintergreen) is widely available in many over-the-counter liniments, ointments, lotions or medicated oils for the relief of musculoskeletal aches and pains. Ingestion of methyl salicylate poses the threat of severe, rapid-onset salicylate poisoning because of its
Dirk W Lachenmeier et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 51, 173-178 (2012-10-09)
Mouthwash ingestion has been observed in settings of restricted availability to alcoholic beverages such as in hospitals, prisons or military establishments. The literature offers limited evidence that ingredients of mouthwash may have health effects above the effects of ethanol. This
Duc-Viet Nguyen et al.
Molecular pharmaceutics, 12(2), 444-452 (2014-12-17)
Controlled release plays an essential role in formulating topical and transdermal drug delivery systems. In this study, we correlated the skin permeation of Sesamin, a lipophilic drug, with the rheological properties of two different organogel carriers, i.e., low molecular weight
Xin Lan et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 102, 281-285 (2012-12-12)
The excited-state properties of intramolecular hydrogen bonding (IMHB) in methyl salicylate (MS) and its effects on the excited-state intramolecular proton transfer (ESIPT) have been investigated using theoretical methods. From the geometric optimization and IR spectra in the ground and excited
A novel mouse model of high flow-induced pulmonary hypertension-surgically induced by right pulmonary artery ligation
Zhang A, et al.
The Journal of Surgical Research, 208, 132-139 (2017)
Evelina Vågesjö et al.
Cell transplantation, 24(2), 263-276 (2014-02-01)
The only clinically available curative treatment of type 1 diabetes mellitus is replacement of the pancreatic islets by allogeneic transplantation, which requires immunosuppressive therapies. Regimens used today are associated with serious adverse effects and impaired islet engraftment and function. The
Lourdes Santana et al.
Journal of medicinal chemistry, 51(21), 6740-6751 (2008-10-07)
The work provides a new model for the prediction of the MAO-A and -B inhibitor activity by the use of combined complex networks and QSAR methodologies. On the basis of the obtained model, we prepared and assayed 33 coumarin derivatives
Carla De Giovanni et al.
Breast cancer research : BCR, 16(1), R10-R10 (2014-01-24)
The availability of mice transgenic for the human HER2 gene (huHER2) and prone to the development of HER2-driven mammary carcinogenesis (referred to as FVB-huHER2 mice) prompted us to study active immunopreventive strategies targeting the human HER2 molecule in a tolerant
Richard Radnovich et al.
Journal of pain research, 7, 727-735 (2014-12-20)
Treatment for pain due to shoulder impingement syndrome (SIS) typically begins conservatively with nonsteroidal anti-inflammatory drugs and physical therapy and can include subacromial injection of corticosteroids, particularly in patients unresponsive to conservative measures. The heated lidocaine/tetracaine (HLT) patch has been
Airborne signalling by methyl salicylate in plant pathogen resistance
Shulaev V, et al.
Nature, 385(6618), 718-718 (1997)
Jian-ping Wang et al.
Journal of ethnopharmacology, 137(3), 1089-1094 (2011-07-30)
Siegesbeckia orientalis has been traditionally used as a topical anti-inflammatory and analgesic agent. Current study was designed to explore the topical anti-inflammatory and analgesic effects of a constituent isolated from Siegesbeckia orientalis (Compositae), in order to validate its folk use.
Jun-Ru Lee et al.
Developmental biology, 463(1), 39-52 (2020-05-04)
Netrin is a remarkably conserved midline landmark, serving as a chemotactic factor that organizes the bilateral neural architecture in the post-gastrula bilaterian embryos. Netrin signal also guides cell migration in many other neural and non-neural organogenesis events in later developmental
Peter O Bayguinov et al.
Journal of neurophysiology, 114(1), 662-676 (2015-05-23)
The mammalian superior colliculus (SC) is a laminar midbrain structure that translates visual signals into commands to shift the focus of attention and gaze. The SC plays an integral role in selecting targets and ultimately generating rapid eye movements to
Jochen Pauwels et al.
Journal of pharmaceutical and biomedical analysis, 60, 51-58 (2011-11-19)
Capsaicinoids, salicylic acid, methyl and ethyl salicylate, glycol monosalicylate, camphor and l-menthol are widely used in topical formulations to relieve local pain. For each separate compound or simple mixtures, quantitative analysis methods are reported. However, for a mixture containing all
Swati S More et al.
ACS chemical neuroscience, 6(2), 306-315 (2014-10-30)
Amyloidopathic disorders such as Alzheimer's disease present symptomology years after the entrenchment of amyloidogenic imbalance. The pathologic α-helix → β-strand conversion of amyloid β(1-42) and amyloid β(1-40) peptides causes neuronal death in the vicinity. Symptomology often presents only after significant
Tracy Greene et al.
Critical reviews in toxicology, 47(2), 98-120 (2016-11-12)
Methyl salicylate is the predominant constituent of oil of wintergreen and is used as a pesticide, a denaturant, an external analgesic, a fragrance ingredient, and a flavoring agent in products such as chewing gum, baked goods, syrups, candy, beverages, ice
Yuancai Dong et al.
Carbohydrate polymers, 94(2), 940-945 (2013-04-03)
The purpose of this study is to synthesize chitosan (CS) nanoparticles (NPs) by ionic gelation with tripolyphosphate (TPP) as crossslinker in static mixers. The proposed static mixing technique showed good control over the ionic gelation process and 152-376 nm CS
X Lu et al.
Oncogene, 33(20), 2655-2664 (2013-06-19)
Nanog is a transcription factor required for maintaining the pluripotency of embryonic stem cells, and is not expressed in most normal adult tissues. However, recent studies have indicated that Nanog is overexpressed in many types of human cancers, including breast
Kelly J Vining et al.
The New phytologist, 206(4), 1406-1422 (2014-10-30)
As a step toward functional annotation of genes required for floral initiation and development within the Eucalyptus genome, we used short read sequencing to analyze transcriptomes of floral buds from early and late developmental stages, and compared these with transcriptomes
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