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Showing 1-30 of 32 results for "M9144" within Papers
Deborah Frenkel et al.
PLoS pathogens, 12(7), e1005733-e1005733 (2016-07-13)
After infection with T. brucei AnTat 1.1, C57BL/6 mice lost splenic B2 B cells and lymphoid follicles, developed poor parasite-specific antibody responses, lost weight, became anemic and died with fulminating parasitemia within 35 days. In contrast, infected C57BL/6 mice lacking
Colleen F Manning et al.
PloS one, 7(6), e38313-e38313 (2012-06-08)
Simultaneous labeling of multiple targets in a single sample, or multiplexing, is a powerful approach to directly compare the amount, localization and/or molecular properties of different targets in the same sample. Here we highlight the robust reliability of the simultaneous
Gerd G Gauglitz et al.
PloS one, 7(2), e29942-e29942 (2012-02-24)
In addition to forming the epithelial barrier against the outside environment keratinocytes are immunologically active cells. In the treatment of severely burned skin, cryoconserved keratinocyte allografts gain in importance. It has been proposed that these allografts accelerate wound healing also
Functional expression of the chemokine receptor CCR7 on fibroblast-like synoviocytes
Bruhl H, et al.
Rheumatology (Basel), 47(12), 1771-1774 (2008)
Andrew M Blagborough et al.
Methods in molecular biology (Clifton, N.J.), 923, 577-600 (2012-09-20)
Here we describe a series of methods that can be used to assess the activities of "vaccines," drugs, and genetically modified vectors, for their abilities to inhibit transmission of Plasmodium from its vertebrate to its mosquito hosts. The selection of
H Brühl et al.
Rheumatology (Oxford, England), 47(12), 1771-1774 (2008-10-08)
We have characterized the expression and the function of the chemokine receptor CCR7 on fibroblast-like synoviocytes (FLS) of patients with RA and OA and on dermal fibroblasts. FLS were obtained after enzymatic digestion of synovial tissue (ST) of patients with
D Stavrou et al.
Journal of the neurological sciences, 80(2-3), 205-220 (1987-09-01)
The establishment of hybridomas after fusion of X63-Ag8.653 mouse myeloma cells and splenocytes from BALB/c mice hyperimmunized against human astrocytomas is presented. The animals were primed with 5 X 10(6) chemically modified uncultured or cultured glioma cells. Six weeks after
Sergey N Arkhipov et al.
Physiological reports, 11(7), e15652-e15652 (2023-04-07)
Development of autosomal dominant polycystic kidney disease (ADPKD) involves renal epithelial cell abnormalities. Cystic fluid contains a high level of ATP that, among other effects, leads to a reduced reabsorption of electrolytes in cyst-lining cells, and thus results in cystic
Yoann Aldon et al.
Molecular therapy. Nucleic acids, 25, 483-493 (2021-10-01)
Self-amplifying mRNA (saRNA) represents a promising platform for nucleic acid delivery of vaccine immunogens. Unlike plasmid DNA, saRNA does not require entry into the nucleus of target cells for expression, having the capacity to drive higher protein expression compared to
P M Glee et al.
Infection and immunity, 69(5), 2815-2820 (2001-04-09)
Adhesion interactions during hematogenous dissemination of Candida albicans likely involve a complex array of host and fungal factors. Possible C. albicans factors include changes in cell surface hydrophobicity and exposed antigens that have been shown in static adhesion assays to
Human Tenon?s Fibroblast-Produced IFNbeta and the Prevention of T-Cell Apoptosis
Chang L, et al.
Investigative Ophthalmology & Visual Science, 42(7), 1531-1538 (2001)
J D Hosenpud et al.
Transplantation, 52(5), 896-903 (1991-11-01)
Cardiac allograft vasculopathy (accelerated transplant atherosclerosis) is considered by most to involve a chronic allogeneic immune response to one or more constituents in the coronary vascular wall. Recent evidence suggests that there is an association between cytomegalovirus infection and the
Signe C Svindland et al.
Influenza and other respiratory viruses, 6(2), 90-100 (2011-07-14)
Development of influenza vaccines that induce mucosal immunity has been highlighted by the World Health Organisation as a priority (Vaccine 2005;23:1529). Dose-sparing strategies and an efficient mass-vaccination regime will be paramount to reduce the morbidity and mortality of a future
In vivo production of interferon beta by human Tenon's fibroblasts; a possible mediator for the development of chronic conjunctival inflammation
Chang L, et al.
The British Journal of Ophthalmology, 86(6), 611-615 (2002)
Zhi Sun et al.
The Journal of general virology, 93(Pt 9), 2008-2016 (2012-06-29)
We have developed a porcine intestine epithelial cell line, designated SD-PJEC for the propagation of influenza viruses. The SD-PJEC cell line is a subclone of the IPEC-J2 cell line, which was originally derived from newborn piglet jejunum. Our results demonstrate
Sudipta Baroi et al.
Bone, 147, 115913-115913 (2021-03-17)
The peroxisome proliferator activated receptor gamma (PPARG) nuclear receptor regulates energy metabolism and insulin sensitivity. In this study, we present novel evidence for an essential role of PPARG in the regulation of osteocyte function, and support for the emerging concept
Development and characterization of swine primary respiratory epithelial cells and their susceptibility to infection by four influenza virus types
Sreenivasan CC, et al.
Virology, 528, 152-163 (2019)
Tine M Søland et al.
Clinical and experimental dental research, 7(1), 70-77 (2020-11-04)
The presence of and the causative role of high-risk human papilloma virus (HPV) is a subject of controversy in oral squamous cell carcinoma (OSCC). The disagreement can be related to the misclassification of OSCC as oropharyngeal squamous cell carcinoma and/or
Milton Thomas et al.
Viruses, 10(6) (2018-06-09)
Influenza viruses infect the epithelial cells of the swine respiratory tract. Cell lines derived from the respiratory tract of pigs could serve as an excellent in vitro model for studying the pathogenesis of influenza viruses. In this study, we examined
L Chang et al.
The British journal of ophthalmology, 86(6), 611-615 (2002-05-30)
Chronic inflammation may develop from failure of the immune system to deactivate itself during resolution of the wound healing response, and is recognised as a major risk factor for trabeculectomy failure. Fibroblast/T cell interactions may contribute to aggressive scarring. Our
Annette L Rothermel et al.
BMC immunology, 5, 5-5 (2004-04-29)
Immune recognition of vascular endothelial cells (EC) has been implicated in allograft rejection, protection against pathogens, and lymphocyte recruitment. However, EC pervade nearly all tissues and predominate in none, complicating any direct test of immune recognition. Here, we examined antigen
Radhey S Kaushik et al.
Journal of virological methods, 148(1-2), 182-196 (2008-01-12)
Mucosal epithelial cells are infected by a wide variety of pathogens and determining their response to infection is critical for understanding disease pathogenesis. A protocol was developed for culturing primary epithelial cells from fetal bovine intestine and the cultured cells
TMEM30A is a candidate interacting partner for the beta-carboxyl-terminal fragment of amyloid-beta precursor protein in endosomes
Takasugi N, et al.
PLoS ONE, 13(8), e0200988-e0200988 (2018)
R S Mathias et al.
The American journal of physiology, 274(6), C1456-C1465 (1998-06-05)
The effect of inositol 1,4,5-trisphosphate (IP3) receptor blockade on platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), endothelin-1 (ET-1), or alpha-thrombin receptor-mediated intracellular Ca2+ (Ca2+i) release was examined using fura 2 microspectrofluorometry in single Chinese hamster ovary cells and myoblasts.
K Murata et al.
British journal of cancer, 68(1), 103-111 (1993-07-01)
The expression of Group-II phospholipase A2 (M-PLA2) was analysed immunohistochemically in malignant, non-malignant (including atrophic, hyperplastic, pseudopyloric metaplastic and intestinal metaplastic) and normal human gastric mucosae. M-PLA2 was consistently detected in the stem cell lineage, pseudopyloric metaplasia and the generative
Chithra C Sreenivasan et al.
Virology, 528, 152-163 (2019-01-08)
Influenza viruses are a group of respiratory pathogens that have evolved into four different types: A, B, C, and D. A common feature is that all four types are capable of replicating and transmitting among pigs. Here, we describe the
Andrea Casasco et al.
Methods in molecular biology (Clifton, N.J.), 289, 229-238 (2004-10-27)
Cell kinetic studies provide important information on histogenesis in vivo and in vitro. In this regard, specific antibodies to cell cycle-related antigens have been raised and characterized, thus permitting the study of cell kinetics using immunochemical methods. Recent advances in
Nobumasa Takasugi et al.
PloS one, 13(8), e0200988-e0200988 (2018-08-08)
Although the aggregation of amyloid-β peptide (Aβ) clearly plays a central role in the pathogenesis of Alzheimer's disease (AD), endosomal traffic dysfunction is considered to precede Aβ aggregation and trigger AD pathogenesis. A body of evidence suggests that the β-carboxyl-terminal
Tirth Uprety et al.
In vitro cellular & developmental biology. Animal, 55(7), 533-547 (2019-06-12)
Intestinal sub-epithelial myofibroblasts (ISEMFs) are mesenchymal cells that do not express cytokeratin but express α-smooth muscle actin and vimentin. Despite being cells with diverse functions, there is a paucity of knowledge about their origin and functions primarily due to the
Pratik Katwal et al.
Cytotechnology, 71(1), 127-148 (2019-01-03)
The intestinal epithelium is a major site of interaction with pathogens. In bovine intestinal epithelial cells (BIECs), Toll-like receptors (TLRs) play an important role in innate immune responses against enteric pathogens. This study is aimed at establishing a stable bovine
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