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Showing 1-13 of 13 results for "MAB3402C3" within Papers
Peng Lu et al.
Investigative ophthalmology & visual science, 63(3), 18-18 (2022-03-17)
Pituitary adenylate cyclase-activating polypeptide (PACAP) has shown potent neuroprotective effects in central nervous system and retina disorders. However, whether PACAP can attenuate retinal neurodegeneration induced by acute ocular hypertension (AOH) and the underlying mechanisms remain unknown. In this study, we
Stephen S Dominy et al.
Science advances, 5(1), eaau3333-eaau3333 (2019-02-13)
Porphyromonas gingivalis, the keystone pathogen in chronic periodontitis, was identified in the brain of Alzheimer's disease patients. Toxic proteases from the bacterium called gingipains were also identified in the brain of Alzheimer's patients, and levels correlated with tau and ubiquitin
Matthias Gralle et al.
Journal of neurochemistry, 156(1), 88-105 (2019-12-31)
Insulin signaling through the insulin receptor has long been studied in classic target organs, such as adipose tissue and skeletal muscle, where one of its effects is to increase glucose uptake. Insulin and insulin receptor are present in many areas
Jian Zhang et al.
Animal cells and systems, 23(1), 32-41 (2019-03-06)
The objective of this study was to clarify the relationship between the effect and associated mechanisms of lithium chloride on neural stem cells (NSCs) and the Wnt signaling pathway. The expression of key molecules proteins related to the Wnt signaling
Galina Dvoriantchikova et al.
Scientific reports, 12(1), 17152-17152 (2022-10-14)
Ischemia-reperfusion (IR) injury is implicated in a large array of pathological conditions in the retina. Increasing experimental evidence suggests that programmed necrosis makes a significant contribution to inflammation and retinal damage triggered by IR. Since there are many types of
Galina Dvoriantchikova et al.
International journal of molecular sciences, 24(12) (2023-06-28)
Retinal ischemia-reperfusion (IR)-which ultimately results in retinal ganglion cell (RGC) death-is a common cause of visual impairment and blindness worldwide. IR results in various types of programmed cell death (PCD), which are of particular importance since they can be prevented
Simona Hankeova et al.
EMBO molecular medicine, 14(12), e15809-e15809 (2022-11-09)
Spontaneous bleeds are a leading cause of death in the pediatric JAG1-related liver disease Alagille syndrome (ALGS). We asked whether there are sex differences in bleeding events in patients, whether Jag1Ndr/Ndr mice display bleeds or vascular defects, and whether discovered
Junjin Lin et al.
Scientific reports, 11(1), 23569-23569 (2021-12-09)
Microvascular compression of the trigeminal root entry zone (TREZ) is the main cause of most primary trigeminal neuralgia (TN), change of glial plasticity was previously studied in the TREZ of TN rat model induced by chronic compression. To better understand
Shahriar SheikhBahaei et al.
The Journal of comparative neurology, 526(13), 2032-2047 (2018-06-12)
Astrocytes, the most abundant and structurally complex glial cells of the central nervous system, are proposed to play an important role in modulating the activities of neuronal networks, including respiratory rhythm-generating circuits of the preBötzinger complex (preBötC) located in the
Ariana Z Turk et al.
The Journal of comparative neurology, 530(2), 574-589 (2021-08-14)
Astrocytes, the star-shaped glial cells, are the most abundant non-neuronal cell population in the central nervous system. They play a key role in modulating activities of neural networks, including those involved in complex motor behaviors. Common marmosets (Callithrix jacchus), the
Kimberley Delaunay et al.
Journal of clinical medicine, 10(13) (2021-07-20)
The aim of this study was to evaluate the potential anti-angiogenic effect of MTRN (meteorin) in the laser-induced CNV rat model and explore its mechanisms of action. MTRN, thrompospondin-1, glial cell markers (GFAP, vimentin), and phalloidin were immuno-stained in non-human
Angela R Dixon et al.
Toxicology in vitro : an international journal published in association with BIBRA, 29(3), 564-574 (2015-01-03)
With m-Dinitrobenzene (m-DNB) as a selected model neurotoxicant, we demonstrate how to assess neurotoxicity, using morphology based measurement of neurite degeneration, in a conventional "full-contact" and a modern "restricted-contact" co-culture of rat cortical neurons and astrocytes. In the "full-contact" co-culture
Madeha Ishag Adam et al.
Neural regeneration research, 18(6), 1364-1370 (2022-12-02)
The trigeminal root entry zone is the zone at which the myelination switches from peripheral Schwann cells to central oligodendrocytes. Its special anatomical and physiological structure renders it susceptible to nerve injury. The etiology of most primary trigeminal neuralgia is
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