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Showing 1-15 of 15 results for "MABS132" within Papers
PET Demonstrates Functional Recovery after Treatment by Danhong Injection in a Rat Model of Cerebral Ischemic-Reperfusion Injury.
Wang, Z; Song, F; Li, J; Zhang, Y; He, Y; Yang, J; Zhou, H; Zhao, T; Fu, W; Xing, P; Wan et al.
Evidence-Based Complementary and Alternative Medicine : ECAM null
Dan Shao et al.
Nature communications, 9(1), 2935-2935 (2018-07-28)
Glucose and branched-chain amino acids (BCAAs) are essential nutrients and key determinants of cell growth and stress responses. High BCAA level inhibits glucose metabolism but reciprocal regulation of BCAA metabolism by glucose has not been demonstrated. Here we show that
A Monnier et al.
Acta physiologica (Oxford, England), 219(4), 790-802 (2016-07-02)
Evidence that brain-derived neurotrophic factor (BDNF), a neurotrophin largely involved in cognition, is expressed by cerebral endothelial cells led us to explore in rats the contribution of the cerebral microvasculature to BDNF found in brain tissue and the link between
Roberta Battistella et al.
International journal of molecular sciences, 22(21) (2021-11-14)
The vascular system is vital for all tissues and the interest in its visualization spans many fields. A number of different plant-derived lectins are used for detection of vasculature; however, studies performing direct comparison of the labeling efficacy of different
Stanley Andrisse et al.
American journal of physiology. Endocrinology and metabolism, 314(4), E353-E365 (2018-01-20)
Hyperandrogenemia and hyperinsulinemia are believed to play prominent roles in polycystic ovarian syndrome (PCOS). We explored the effects of low-dose dihydrotestosterone (DHT), a model of PCOS, on insulin signaling in metabolic and reproductive tissues in a female mouse model. Insulin
Benjamin H Singer et al.
The Journal of comparative neurology, 514(6), 567-582 (2009-04-14)
Forebrain neurogenesis persists throughout life in the rodent subventricular zone (SVZ) and hippocampal dentate gyrus (DG). Several strategies have been employed to eliminate adult neurogenesis and thereby determine whether depleting adult-born neurons disrupts specific brain functions, but some approaches do
Majid Iqbal et al.
Endocrinology, 152(3), 1067-1079 (2011-01-18)
The early fetal brain is susceptible to teratogens in the maternal circulation, because brain microvessel expression of drug efflux transporter, P-glycoprotein (P-gp), is very low. However, there is a dramatic up-regulation of brain microvessel P-gp in late gestation. This study
Oscar Manouchehrian et al.
Journal of neuroinflammation, 18(1), 34-34 (2021-01-31)
The exchange of cerebrospinal (CSF) and interstitial fluid is believed to be vital for waste clearance in the brain. The sleep-dependent glymphatic system, which is comprised of perivascular flow of CSF and is largely dependent on arterial pulsatility and astrocytic
Endotoxin-induced inflammation down-regulates L-type amino acid transporter 1 (LAT1) expression at the blood-brain barrier of male rats and mice.
Wittmann, G; Mohacsik, P; Balkhi, MY; Gereben, B; Lechan, RM
Fluids and Barriers of the Cns null
Shikha Prasad et al.
Fluids and barriers of the CNS, 12, 18-18 (2015-07-25)
Diabetes and tobacco smoking are significant public health concerns which have been shown to independently impact the blood-brain barrier (BBB). Since smoking is a risk factor for diabetes and shares some of the common pathological pathways leading to metabolic abnormalities
Martin Pedard et al.
Frontiers in physiology, 8, 1125-1125 (2018-01-30)
Cognitive abilities are largely dependent on activation of cerebral tropomyosin-related kinase B receptors (TrkB) by brain-derived neurotrophic factor (BDNF) that is secreted under a bioactive form by both neurons and endothelial cells. In addition, there is mounting evidence for a
Jiaming Zhou et al.
ASN neuro, 15, 17590914231151534-17590914231151534 (2023-02-18)
Retinitis pigmentosa (RP) is an inherited disorder that results in vision impairment but general and mutation-independent therapeutic strategies are not available. However, it is widely regarded that the cGMP system, including cGMP and its interactor cGMP-dependent protein kinase (PKG), acts
Linn Stenfelt et al.
Transfusion, 59(3), 1108-1117 (2019-01-01)
The P1 antigen was first described in 1927 and belongs to the P1PK histo-blood group system, together with Pk and NOR. The A4GALT-encoded 4-α-galactosyltransferase synthesizes these antigens and has been considered to extend glycolipids exclusively. However, contradicting studies have been
Alexander E Ropper et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(5), E820-E829 (2017-01-18)
Mesenchymal stromal stem cells (MSCs) isolated from adult tissues offer tangible potential for regenerative medicine, given their feasibility for autologous transplantation. MSC research shows encouraging results in experimental stroke, amyotrophic lateral sclerosis, and neurotrauma models. However, further translational progress has
Daniele Tomassoni et al.
Nutrients, 12(5) (2020-05-14)
Metabolic syndrome (MetS) is an association between obesity, dyslipidemia, hyperglycemia, hypertension, and insulin resistance. A relationship between MetS and vascular dementia was hypothesized. The purpose of this work is to investigate brain microanatomy alterations in obese Zucker rats (OZRs), as
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