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Showing 1-27 of 27 results for "MAK009" within Papers
Anika E Wagner et al.
Oncotarget, 6(31), 30568-30578 (2015-09-17)
In this study, we tested whether a standardized epigallocatechin-3-gallate (EGCG) rich green tea extract (comprising > 90% EGCG) affects fitness and lifespan as well as parameters of glucose metabolism and energy homeostasis in the fruit fly, Drosophila melanogaster. Following the
Mamta Rai et al.
Cell metabolism, 33(6), 1137-1154 (2021-03-28)
Neurodegeneration in the central nervous system (CNS) is a defining feature of organismal aging that is influenced by peripheral tissues. Clinical observations indicate that skeletal muscle influences CNS aging, but the underlying muscle-to-brain signaling remains unexplored. In Drosophila, we find
Philip van der Zee et al.
Purinergic signalling (2018-05-13)
Recent research suggested an important role for pulmonary extracellular adenosine triphosphate (ATP) in the development of ventilation-induced lung injury. This injury is induced by mechanical deformation of alveolar epithelial cells, which in turn release ATP to the extracellular space. Measuring
Usefulness of salivary alpha amylase as a biomarker of chronic stress and stress related oral mucosal changes?a pilot study.
Vineetha R, et al.
Journal of Clinical and Experimental Dentistry, 6(2), e132-e132 (2014)
Natalie Chiu et al.
Food hydrocolloids, 69, 450-458 (2017-08-05)
Sodium (salt) was encapsulated within the inner water phase of w1/o/w2 food emulsions externally stabilised by starch particles with the ultimate aim of enhancing saltiness perception. The physical properties of the starch particles were modified by octenyl succinic anhydride (OSA)
Yuqiang Shan et al.
International journal of molecular medicine, 50(1) (2022-05-19)
Acute pancreatitis (AP) is an inflammatory disorder that has been associated with systemic inflammatory response syndrome. Ginsenoside Rg3 is a major active component of Panax ginseng, which has been demonstrated to exert potent protective effects on hyperglycemia and diabetes. However, it
José Rodolfo R Carvalho et al.
Journal of animal physiology and animal nutrition, 103(1), 8-16 (2018-11-30)
Eighteen Nellore and 18 Angus young bulls with BW of 381 ± 12 kg were randomly assigned into two feeding groups (whole shelled corn [WSC] or ground corn with silage [GC]) to evaluate the interaction of breed and diet on total nutrient digestibility
Yanxia Gao et al.
Frontiers in pharmacology, 12, 611433-611433 (2021-05-11)
It is noted that elevated serum amylase levels suggesting pancreatic damage has an association with prognosis in PQ patients. This study aimed to determine whether PQ can cause pancreatic damage. The two conventional models (intragastric infusion (iG) and intraperitoneal injection
Production, Biocatalysis and Industrial Applications
Goutam B.
Biotechnology of microbial enzymes (2016)
High endogenous salivary amylase activity is associated with improved glycemic homeostasis following starch ingestion in adults.
Mandel A L, et al.
The Journal of Nutrition, 142(5), 853-858 (2012)
Tania Michelle Roberts et al.
Yeast (Chichester, England), 37(5-6), 336-347 (2020-02-18)
Saccharomyces cerevisiae cells grown in a small volume of chemically defined media neither reach the desired cell density nor grow at a fast enough rate to scale down the volume and increase the sample number of classical biochemical assays, as
Donnele Daley et al.
Cell, 166(6), 1485-1499 (2016-08-30)
Inflammation is paramount in pancreatic oncogenesis. We identified a uniquely activated γδT cell population, which constituted ∼40% of tumor-infiltrating T cells in human pancreatic ductal adenocarcinoma (PDA). Recruitment and activation of γδT cells was contingent on diverse chemokine signals. Deletion, depletion
Stephanie Perkail et al.
Nature communications, 11(1), 3018-3018 (2020-06-17)
Chronic pancreatitis represents a risk factor for the development of pancreatic cancer. We find that heterozygous loss of histone H2A lysine 119 deubiquitinase BAP1 (BRCA1 Associated Protein-1) associates with a history of chronic pancreatitis and occurs in 25% of pancreatic
Galactose protects against cell damage in mouse models of acute pancreatitis.
Peng S, et al.
The Journal of Clinical Investigation (2018)
Shuang Peng et al.
The Journal of clinical investigation, 128(9), 3769-3778 (2018-06-13)
Acute pancreatitis (AP), a human disease in which the pancreas digests itself, has substantial mortality with no specific therapy. The major causes of AP are alcohol abuse and gallstone complications, but it also occurs as an important side effect of
William Vaughn McCall et al.
Heliyon, 5(5), e01709-e01709 (2019-06-14)
Overactivity of the noradrenergic (NE) system within the central nervous system (CNS) has been postulated as a key pathophysiology of posttraumatic stress disorder (PTSD). The activity of the enzyme salivary α-amylase (sAA) has been proposed as an indirect measure of
Adam M Passman et al.
Disease models & mechanisms, 8(12), 1635-1641 (2015-10-27)
The choline-deficient, ethionine-supplemented (CDE) dietary model induces chronic liver damage, and stimulates liver progenitor cell (LPC)-mediated repair. Long-term CDE administration leads to hepatocellular carcinoma in rodents and lineage-tracing studies show that LPCs differentiate into functional hepatocytes in this model. The
Lan Ao et al.
Ultrasonics, 80, 113-118 (2017-05-24)
To investigate the safety of focused ultrasound (FUS) partial ablation on the pancreas of Sprague Dawley® (SD) rats by histopathological examination of the outcome and investigation of glycometabolism function changes after local ablation. A total of 135 healthy SD rats
Evaluation of amylase and lipase levels in blunt trauma abdomen patients.
Kumar S, et al.
Journal of emergencies, trauma, and shock, 5(2), 135-135 (2012)
Ana Margarida Silva et al.
Molecules (Basel, Switzerland), 26(8) (2021-05-01)
During kiwiberry production, different by-products are generated, including leaves that are removed to increase the fruit's solar exposure. The aim of this work was to extract bioactive compounds from kiwiberry leaf by employing microwave-assisted extraction (MAE). Compatible food solvents (water
Paul C Moore et al.
Cancer research, 79(24), 6190-6203 (2019-11-02)
Master regulators of the unfolded protein response (UPR), IRE1α and PERK, promote adaptation or apoptosis depending on the level of endoplasmic reticulum (ER) stress. Although the UPR is activated in many cancers, its effects on tumor growth remain unclear. Derived
Ali Hanafiah Hakim et al.
Animals : an open access journal from MDPI, 12(7) (2022-04-13)
The study aimed at determining the ileal nutrient digestibility, digestive enzyme activity, intestinal morphology, and nutrient transporters mRNA expressions in broiler chickens fed with fermented PKC (LPKC) based diets with different levels of fat supplementation under hot and humid conditions.
A feasibility study into adenosine triphosphate measurement in exhaled breath condensate: a potential bedside method to monitor alveolar deformation.
van der Zee P, et al.
Purinergic Signaling, 1-7 (2018)
Berra Erkosar et al.
mBio, 8(5) (2017-10-27)
Numerous studies have shown that animal nutrition is tightly linked to gut microbiota, especially under nutritional stress. In Drosophila melanogaster, microbiota are known to promote juvenile growth, development, and survival on poor diets, mainly through enhanced digestion leading to changes
X Chen et al.
Poultry science, 95(4), 834-841 (2016-01-08)
A 14-d study was conducted to determine the impact of dietary crude protein concentration on performance, serum biochemistry, and nutrient digestive functions in Pekin ducklings during aflatoxicosis. A total of 144 male Pekin ducklings were randomly allotted to 4 dietary
Epigallocatechin gallate affects glucose metabolism and increases fitness and lifespan in Drosophila melanogaster.
Wagner A E, et al.
Oncotarget, 6(31), 30568-30568 (2015)
Dalila Azzout-Marniche et al.
The Journal of nutrition, 149(2), 270-279 (2019-02-13)
We have reported large differences in adiposity (fat mass/body weight) gain between rats fed a low-fat, high-starch diet, leading to their classification into carbohydrate "sensitive" and "resistant" rats. In sensitive animals, fat accumulates in visceral adipose tissues, leading to the
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