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Showing 1-30 of 61 results for "N2280" within Papers
Bas M J Olthof et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(5), 876-887 (2018-12-12)
Nitric oxide (NO) is a neurotransmitter synthesized in the brain by neuronal nitric oxide synthase (nNOS). Using immunohistochemistry and confocal imaging in the inferior colliculus (IC, auditory midbrain) of the guinea pig (Cavia porcellus, male and female), we show that
Shilpa S Dhar et al.
Biochimica et biophysica acta, 1793(10), 1604-1613 (2009-07-21)
Neuronal activity is highly dependent on energy metabolism; yet, the two processes have traditionally been regarded as independently regulated at the transcriptional level. Recently, we found that the same transcription factor, nuclear respiratory factor 1 (NRF-1) co-regulates an important energy-generating
Jun-Ping Li et al.
World journal of gastroenterology, 21(34), 9936-9944 (2015-09-18)
To investigate the distribution and neurochemical phenotype of endomorphin-2 (EM-2)-containing neurons in the submucosal plexus of the rat colon. The mid-colons between the right and left flexures were removed from rats, and transferred into Kreb's solution. For whole-mount preparations, the
Elias Zintzaras et al.
Genetics in medicine : official journal of the American College of Medical Genetics, 11(10), 695-706 (2009-09-24)
Candidate-gene association studies that examined the association between polymorphisms of endothelial nitric oxide synthase (NOS3) gene (G894T, 4b/a, and T786C) and diabetic nephropathy or diabetes leading to severe nephropathy produced inconclusive results. Thus, a meta-analysis of all candidate-gene association studies
Donald B Hoover et al.
Autonomic neuroscience : basic & clinical, 141(1-2), 38-45 (2008-06-19)
While much is known about the influence of ventricular afferent neurons on cardiovascular function in the dog, identification of the neurochemicals transmitting cardiac afferent signals to central neurons is lacking. Accordingly, we identified ventricular afferent neurons in canine dorsal root
W Sienkiewicz et al.
Anatomia, histologia, embryologia, 39(2), 152-159 (2010-01-15)
In this study, the presence of several neurotransmitters and transmitter synthesizing enzymes was studied in hypoglossal nucleus (HN) of the juvenile (4 months old) female pigs (n = 3). Double-labeling immunofluorescence revealed neurones expressing cholinacetyltranspherase (ChAT), calcitonin gene-related peptide (CGRP)
Jeroen Van Genechten et al.
American journal of respiratory cell and molecular biology, 30(1), 20-30 (2003-06-21)
The Fawn-Hooded rat (FHR), a model for primary pulmonary hypertension, shows an unexplained hypersensitivity to airway hypoxia. Because pulmonary neuroepithelial bodies (NEBs) appear to express a functional oxygen-sensing mechanism and an extensive sensory innervation, possible changes in this system should
A Kozłowska et al.
Journal of molecular neuroscience : MN, 54(1), 10-19 (2014-02-13)
We revealed earlier that induction of ovarian cysts in gilts by dexamethasone phosphate disodium salt (DXM) administration from the follicular phase of the estrous cycle (EC) changed the cholinergic innervation of the gonad. In the present study, the innervation of
Sławomir Gonkowski et al.
Journal of molecular neuroscience : MN, 56(4), 878-886 (2015-03-17)
The aim of this study was to investigate, whether low doses (25 % of no observable adverse effect levels values) of zearalenone (ZEN) can affect the expression of active substances in nerve fibers in the muscular layer of porcine ileum. The
Kyle T Nakamoto et al.
Hearing research, 306, 131-144 (2013-10-22)
Projections from auditory cortex (AC) affect how cells in both inferior colliculi (IC) respond to acoustic stimuli. The large projection from the AC to the ipsilateral IC is usually credited with the effects in the ipsilateral IC. The circuitry underlying
Jeroen Van Genechten et al.
The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology, 272(1), 446-453 (2003-04-22)
The Fawn-Hooded rat (FHR) strain reveals a congenital predisposition to primary (idiopathic) pulmonary hypertension (PPH), and can therefore be regarded as an animal model in which to study possible mechanisms underlying an inherited susceptibility to pulmonary hypertension. Pulmonary hypertension can
Joanna Wojtkiewicz et al.
Journal of molecular neuroscience : MN, 48(3), 766-776 (2012-07-14)
The SLC30 family of divalent cation transporters is thought to be involved in the transport of zinc in a variety of cellular pathways. Zinc transporter 3 (ZnT3) is involved in the transport of zinc into synaptic vesicles or intracellular organelles.
Elevated expression of CAPON and neuronal nitric oxide synthase in the sciatic nerve of rats following constriction injury
Cui Z, et al.
The Veterinary Journal, 187(3), 374-380 (2011)
Adam Hockley et al.
The European journal of neuroscience, 51(4), 963-983 (2019-09-09)
The gaseous free radical, nitric oxide (NO) acts as a ubiquitous neuromodulator, contributing to synaptic plasticity in a complex way that can involve either long term potentiation or depression. It is produced by neuronal nitric oxide synthase (nNOS) which is
Nitric oxide mediates feedback inhibition in angiotensin II-induced upregulation of vasopressin mRNA
Zhang L, et al.
Peptides, 30(5), 913-917 (2009)
Nichole L Beebe et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(14), 3988-3999 (2016-04-08)
Inhibition plays an important role in shaping responses to stimuli throughout the CNS, including in the inferior colliculus (IC), a major hub in both ascending and descending auditory pathways. Subdividing GABAergic cells has furthered the understanding of inhibition in many
Edward C Harding et al.
Current biology : CB, 28(14), 2263-2273 (2018-07-19)
Mammals, including humans, prepare for sleep by nesting and/or curling up, creating microclimates of skin warmth. To address whether external warmth induces sleep through defined circuitry, we used c-Fos-dependent activity tagging, which captures populations of activated cells and allows them
Sumit Sarkar et al.
The European journal of neuroscience, 26(8), 2228-2238 (2007-10-12)
Neurons in the rostral raphe pallidus (rRP) have been proposed to mediate experimental stress-induced tachycardia and fever in rats, and projections from the dorsomedial hypothalamus (DMH) may signal their activation in these settings. Thus, we examined c-fos expression evoked by
Joanna Wojtkiewicz et al.
Cell and tissue research, 350(2), 215-223 (2012-08-25)
Zinc ions in the synaptic vesicles of zinc-enriched neurons (ZEN) seem to have an important role in normal physiological and pathophysiological processes in target organ innervation. The factor directly responsible for the transport of zinc ions into synaptic vesicles is
Sales Ibiza et al.
Immunity, 24(6), 753-765 (2006-06-20)
The role of nitric oxide (NO) in T cells remains controversial, and the origin and localization of endogenous NO and whether it regulates lymphocyte activation are unclear. We show here that, within minutes of binding to antigen, T cells produce
R C Rogers et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 285(2), R479-R489 (2003-04-26)
Activation of esophageal mechanosensors excites neurons in and near the central nucleus of the solitary tract (NSTc). In turn, NSTc neurons coordinate the relaxation of the stomach [i.e., the receptive relaxation reflex (RRR)] by modulating the output of vagal efferent
K Ashutosh
Current opinion in pulmonary medicine, 6(1), 21-25 (1999-12-23)
Nitric oxide (NO) is synthesized from the amino acid arginine by enzymes called nitric oxide synthases. NO has an important physiologic role in the regulation of vascular tone, response to vascular injury, and hemostasis. It also acts as a neurotransmitter
Eszter Szabadits et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(30), 8101-8111 (2007-07-27)
Nitric oxide (NO) plays an important role in synaptic plasticity as a retrograde messenger at glutamatergic synapses. Here we describe that, in hippocampal pyramidal cells, neuronal nitric oxide synthase (nNOS) is also associated with the postsynaptic active zones of GABAergic
Żaneta Listowska et al.
International journal of molecular sciences, 22(5) (2021-03-07)
The present study investigated the effect of unilateral axotomy of urinary bladder trigone (UBT)-projecting nerve fibers from the right anterior pelvic ganglion (APG) on changes in the chemical coding of their neuronal bodies. The study was performed using male pigs
Emily McMains et al.
PloS one, 6(3), e17647-e17647 (2011-03-17)
Members of the ubiquitously expressed CLC protein family of chloride channels and transporters play important roles in regulating cellular chloride and pH. The CLCs that function as Cl(-)/H(+) antiporters, ClCs 3-7, are essential in particular for the acidification of endosomal
The distribution of nitric oxide synthase in the inferior colliculus of guinea pig
Coote EJ, et al.
Neuroscience, 154(1), 218-225 (2008)
Lars Dittrich et al.
Frontiers in neural circuits, 6, 31-31 (2012-06-09)
We have previously demonstrated that Type I neuronal nitric oxide synthase (nNOS)-expressing neurons are sleep-active in the cortex of mice, rats, and hamsters. These neurons are known to be GABAergic, to express Neuropeptide Y (NPY) and, in rats, to co-express
The complex contribution of NOS interneurons in the physiology of cerebrovascular regulation
Duchemin S, et al.
Frontiers in Neural Circuits, 6 (2012)
Thomas Rhomberg et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(31), 6983-7003 (2018-06-30)
In cortical structures, principal cell activity is tightly regulated by different GABAergic interneurons (INs). Among these INs are vasoactive intestinal polypeptide-expressing (VIP+) INs, which innervate preferentially other INs, providing a structural basis for temporal disinhibition of principal cells. However, relatively
Linda Katona et al.
Hippocampus, 27(4), 359-377 (2016-12-21)
Long-range glutamatergic and GABAergic projections participate in temporal coordination of neuronal activity in distributed cortical areas. In the hippocampus, GABAergic neurons project to the medial septum and retrohippocampal areas. Many GABAergic projection cells express somatostatin (SOM+) and, together with locally
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