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Showing 1-23 of 23 results for "N7782" within Papers
Yu-Lun Wang et al.
Molecular medicine reports, 14(4), 3559-3564 (2016-08-31)
Tormentic acid (TA) is a triterpene isolated from the stem bark of the plant Vochysia divergens and has been reported to exhibit anticancer, anti‑inflammatory and anti‑atherogenic properties. However, the functions of TA in hydrogen peroxide (H2O2)‑induced oxidative stress and inflammation in
Localization of the human gene for inducible nitric oxide synthase (NOS2) to chromosome 17q11. 2-q12
Marsden PA, et al.
Genomics, 19(1) (1994)
Heterotrimeric G protein-dependent WNT-5A signaling to ERK1/2 mediates distinct aspects of microglia proinflammatory transformation
Halleskog C, et al.
Journal of Neuroinflammation, 9(1), 111-111 (2012)
Cole D Libner et al.
The Journal of comparative neurology, 528(10), 1704-1724 (2019-12-25)
Neurodegeneration, including loss of neurons and axons, is a feature of progressive forms of multiple sclerosis (MS). The mechanisms underlying neurodegeneration are mostly unknown. Research implicates autoimmunity to nonmyelin self-antigens as important contributors to disease pathogenesis. Data from our lab
Monoranjan Boro et al.
Scientific reports, 6, 37695-37695 (2016-11-25)
Mycobacterium tuberculosis (Mtb) pathogenesis encompasses a plethora of finely regulated alterations within the host which eventually coin the outcome of infection. Chemokines are important components in directing immune cell recruitment to the site of infection, and shaping the disease progression.
Sung-Suk Suh et al.
International journal of medical sciences, 15(9), 929-936 (2018-07-17)
Inflammation mediated by the innate immune system is an organism's protective mechanism against infectious environmental risk factors. It is also a driver of the pathogeneses of various human diseases, including cancer development and progression. Microalgae are increasingly being focused on
Dag Eckersten et al.
Regulatory peptides, 174(1-3), 32-37 (2011-11-29)
Production of nitric oxide through the action of nitric oxide synthase (NOS) has been detected in the islets of Langerhans. The inducible isoform of NOS (iNOS) is induced by cytokines and might contribute to the development of type-1 diabetes, while
Kasturi Mahadik et al.
Frontiers in immunology, 9, 85-85 (2018-02-17)
Mycobacteria propelled modulation of host responses is of considerable interest in the face of emerging drug resistance. Although it is known that Abl tyrosine kinases affect entry and persistence of mycobacteria, mechanisms that couple c-Abl to proximal signaling pathways during
Ying Guo et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(11), 12164-12174 (2019-08-03)
Variants in the gene encoding the triggering receptor expressed on myeloid cells 2 (TREM2) are known to increase the risk of developing Alzheimer disease and Parkinson's disease (PD). However, the potential role of TREM2 effect on synucleinopathy has not been
Ayan Srivastava et al.
Journal of fish diseases, 43(8), 941-953 (2020-07-04)
This study was carried out to comprehend the pathogenicity of the bacteria in the epidermis of Labeo rohita inoculated with Aeromonas hydrophila. Alterations in the histopathology of the epidermis were examined using scanning electron microscopy, light microscopy and the localization
Ruth I Carlson et al.
Conservation physiology, 4(1), cow001-cow001 (2016-06-14)
A novel antibody-based protein microarray was developed that simultaneously determines expression of 31 stress-associated proteins in skin samples collected from free-ranging grizzly bears (Ursus arctos) in Alberta, Canada. The microarray determines proteins belonging to four broad functional categories associated with
Inducible nitric oxide synthase is a key host factor for toxoplasma GRA15-dependent disruption of the gamma interferon-induced antiparasitic human response
Bando H, et al.
mBio, 9(5), e01738-e01718 (2018)
Inducible nitric oxide synthase 2 promoter polymorphism and malaria disease severity in children in Southern Ghana
Dzodzomenyo M, et al.
PLoS ONE, 13(8), e0202218-e0202218 (2018)
Savita Verma et al.
Frontiers in immunology, 8, 658-658 (2017-06-27)
Pneumonitis and pulmonary fibrosis are predominant consequences of radiation exposure, whether planned or accidental. The present study, demonstrates radioprotective potential of a formulation, prepared by combining podophyllotoxin and rutin (G-003M), in mice exposed to 11 Gy thoracic gamma radiation (TGR). Treated
J H Bach et al.
Journal of neurochemistry, 78(1), 109-120 (2001-07-04)
One of the pathophysiological features of Alzheimer's disease is astrocytosis around senile plaques. Reactive astrocytes may produce proinflammatory mediators, nitric oxide, and subsequent reactive oxygen intermediates such as peroxynitrites. In the present study, we investigated the possible role of the
Xiyue Zhang et al.
British journal of pharmacology, 178(23), 4608-4625 (2021-07-16)
Effective anti-fibrotic therapeutic solutions are unavailable so far. The heat shock protein 90 (HSP90) exerts deleterious effects in some fibrotic diseases. S-nitrosylation (SNO) of HSP90 affects its own function. However, little is known about its role in pathological stress. Here
Carina Halleskog et al.
Journal of neuroinflammation, 9, 111-111 (2012-06-01)
WNT-5A signaling in the central nervous system is important for morphogenesis, neurogenesis and establishment of functional connectivity; the source of WNT-5A and its importance for cellular communication in the adult brain, however, are mainly unknown. We have previously investigated the
Vera Paschon et al.
Scientific reports, 9(1), 14063-14063 (2019-10-03)
During the progression of the neurodegenerative process, mitochondria participates in several intercellular signaling pathways. Voltage-dependent anion-selective channel 1 (VDAC1) is a mitochondrial porin involved in the cellular metabolism and apoptosis intrinsic pathway in many neuropathological processes. In spinal cord injury
Matías Mosqueira et al.
Physiological genomics, 51(4), 109-124 (2019-03-02)
Sustained chronic hypoxia (CH) produces morphological and functional changes in the carotid body (CB). Nitric oxide (NO) and endothelin-1 (ET-1) play a major role as modulators of the CB oxygen chemosensory process. To characterize the effects of CH related to
Chronic ethanol consumption induces histopathological changes and increases nitric oxide generation in the rat liver
Tirapelli LF, et al.
Tissue & cell, 43(6), 384-391 (2011)
Stanislav Rodkin et al.
Biomedicines, 10(7) (2022-07-28)
Peripheral-nerve injury is a frequent cause of disability. Presently, no clinically effective neuroprotectors have been found. We have studied the NO-dependent expression of p53 in the neurons and glial cells of the dorsal root ganglia (DRG) of a rat's spinal
TREM2 overexpression attenuates neuroinflammation and protects dopaminergic neurons in experimental models of Parkinson's disease
Ren M, et al.
Experimental neurology, 302, 205-213 (2018)
Vinay Kumar Singh et al.
Reproduction (Cambridge, England), 153(2), 133-146 (2016-11-07)
The present study was undertaken to understand the physiological significance of the existence of nitric oxide synthase (NOS)/nitric oxide (NO) system in fish ovary. For this, two doses of NO donor, sodium nitroprusside (SNP, 25 µg and 50 µg) and NOS inhibitor
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