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Showing 1-30 of 246 results for "N8878" within Papers
Masayuki Ohtsuka et al.
Antimicrobial agents and chemotherapy, 53(7), 3147-3149 (2009-05-06)
Six Bordetella pertussis strains isolated from children in Japan from 2004 to 2006 showed high-level resistance to nalidixic acid (NAL; MIC, >256 microg/ml) and decreased susceptibilities to fluoroquinolones. All of the NAL-resistant strains had the same D87G mutation in gyrA.
Ekambaram Ramesh et al.
Bioorganic & medicinal chemistry, 17(2), 660-666 (2008-12-23)
Synthesis of a series of novel tetrahydroquinoline annulated heterocycles has been accomplished by intramolecular imino and bisimino Diels-Alder reaction. These compounds were evaluated for their antibacterial activity. All the synthetic compounds, exhibited good antibacterial activity against microorganisms of which one
Michelle M Butler et al.
Antimicrobial agents and chemotherapy, 51(1), 119-127 (2006-11-01)
The anilinouracils (AUs) such as 6-(3-ethyl-4-methylanilino)uracil (EMAU) are a novel class of gram-positive, selective, bactericidal antibacterials which inhibit pol IIIC, the gram-positive-specific replicative DNA polymerase. We have linked various fluoroquinolones (FQs) to the N-3 position of EMAU to generate a
Carla B Schubiger et al.
Applied and environmental microbiology, 81(2), 658-665 (2014-11-09)
Flavobacterium psychrophilum causes bacterial cold-water disease in multiple fish species, including salmonids. An autochthonous Enterobacter strain (C6-6) inhibits the in vitro growth of F. psychrophilum, and when ingested as a putative probiotic, it provides protection against injection challenge with F.
Marianne Gunell et al.
Antimicrobial agents and chemotherapy, 53(9), 3832-3836 (2009-07-15)
Nontyphoidal Salmonella enterica strains with a nonclassical quinolone resistance phenotype were isolated from patients returning from Thailand or Malaysia to Finland. A total of 10 isolates of seven serovars were studied in detail, all of which had reduced susceptibility (MIC
Feng Long et al.
Antimicrobial agents and chemotherapy, 52(9), 3052-3060 (2008-07-02)
Active efflux of antimicrobial agents is one of the most important adapted strategies that bacteria use to defend against antimicrobial factors that are present in their environment. The NorM protein of Neisseria gonorrhoeae and the YdhE protein of Escherichia coli
Vincent Cattoir et al.
Antimicrobial agents and chemotherapy, 52(8), 2929-2932 (2008-06-04)
A novel QnrB-like plasmid-mediated resistance determinant, QnrB19, was identified from an Escherichia coli clinical isolate from Colombia. Its gene was associated with an ISEcp1-like insertion element that did not act as a promoter for its expression. Using an in vitro
Guntis Cepurnieks et al.
Journal of pharmaceutical and biomedical analysis, 102, 184-192 (2014-10-06)
A new multi-class method has been developed for the identification and quantification of the residues of 26 antibiotics from different classes (sulfonamides, macrolides, tetracyclines, penicillins, and quinolones) in milk and meat by ultra performance liquid chromatography coupled to hybrid quadrupole
Janelle N Ruiz et al.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 23(8), 2391-2398 (2015-04-16)
Cancer patients treated with targeted therapies (e.g., epidermal growth factor receptor inhibitors) are susceptible to dermatologic adverse events (AEs) including secondary skin infections. Whereas infections such as paronychia and cellulitis have been reported, nasal vestibulitis (NV) has not been described
Eun Sil Kim et al.
Antimicrobial agents and chemotherapy, 53(6), 2643-2645 (2009-03-18)
The aac(6')-Ib gene was detected in 86 of 555 (15.5%) Enterobacteriaceae isolates. Among these 86 aac(6')-Ib-positive isolates, 19 (22.0%) were positive for aac(6')-Ib-cr: 4 of 31 (12.9%) Enterobacter spp., 7 of 13 (53.8%) Escherichia coli isolates, and 8 of 42
Mohamed Nawaz et al.
International journal of food microbiology, 155(3), 179-184 (2012-03-13)
A study was undertaken to isolate and characterize tetracycline and nalidixic acid-resistant Klebsiella spp. in farm-raised, imported shrimp sold in the United States. Sixty-seven multiple antibiotic-resistant Klebsiella spp. strains were isolated from imported shrimp samples. Using morphological and biochemical methods
Guyue Cheng et al.
Analytical and bioanalytical chemistry, 406(30), 7899-7910 (2014-10-31)
Fluoroquinolones (FQNs) are broad-spectrum antibacterial agents widely used in animal husbandry and aquaculture. The residues and antimicrobial resistance of such antibiotics are a major public health concern. To realize multianalyte detection of FQN residues, a genetically modified bacterium, Escherichia coli
Mode of action of nalidixic acid.
A Bauernfeind
Antibiotics and chemotherapy, 17, 122-136 (1971-01-01)
Zhichao Liu et al.
PLoS computational biology, 7(12), e1002310-e1002310 (2011-12-24)
Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI types (hepatotoxic side effects) seen in the clinic can be translated
Detection of the pandemic O25-ST131 human virulent Escherichia coli CTX-M-15-producing clone harboring the qnrB2 and aac(6')-Ib-cr genes in a dog.
Constança Pomba et al.
Antimicrobial agents and chemotherapy, 53(1), 327-328 (2008-11-13)
Benoît Doublet et al.
Antimicrobial agents and chemotherapy, 54(1), 45-51 (2009-11-04)
Pseudomonas luteola (formerly classified as CDC group Ve-1 and named Chryseomonas luteola) is an unusual pathogen implicated in rare but serious infections in humans. A novel beta-lactamase gene, bla(LUT-1), was cloned from the whole-cell DNA of the P. luteola clinical
Mariateresa Coppola et al.
Clinical and vaccine immunology : CVI, 22(9), 1060-1069 (2015-07-24)
Responsible for 9 million new cases of active disease and nearly 2 million deaths each year, tuberculosis (TB) remains a global health threat of overwhelming dimensions. Mycobacterium bovis BCG, the only licensed vaccine available, fails to confer lifelong protection and
Shabnam Shahida et al.
Environmental monitoring and assessment, 185(2), 1613-1626 (2012-05-15)
In this work, spectrophotometer was used as a detector for the determination of uranium from water, biological, and ore samples with a flow injection system coupled with solid phase extraction. In order to promote the online preconcentration of uranium, a
S Page et al.
Antimicrobial agents and chemotherapy, 52(11), 4155-4158 (2008-08-30)
Fluoroquinolone resistance in Streptococcus pneumoniae mainly involves stepwise mutations predominantly in the parC and gyrA genes. We have developed a single-run real-time PCR assay for detection of the four most common mutations in the quinolone resistance-determining regions of these genes.
Kaitlin L McDaniel et al.
Infection and immunity, 83(7), 2984-2991 (2015-05-13)
Vitamin A deficiency (A(-)) remains a public health concern in developing countries and is associated with increased susceptibility to infection. Citrobacter rodentium was used to model human Escherichia coli infections. A(-) mice developed a severe and lethal (40%) infection. Vitamin
RmtC 16S rRNA methyltransferase in Australia.
Zhiyong Zong et al.
Antimicrobial agents and chemotherapy, 52(2), 794-795 (2007-11-21)
Indu Upadhyaya et al.
Poultry science, 94(7), 1685-1690 (2015-05-27)
This study investigated the efficacy of two GRAS (generally regarded as safe)-status, plant-derived antimicrobials (PDAs), namely trans-cinnamaldehyde (TC) and eugenol (EUG) applied as a fumigation treatment in reducing SE on embryonated egg shells. Egg shells of day-old embryonated eggs were
High prevalence of CTX-M-type beta-lactamases among clinical isolates of Enterobacteriaceae in Bamako, Mali.
Véronique Duval et al.
Antimicrobial agents and chemotherapy, 53(11), 4957-4958 (2009-09-02)
Bea Clarise B Garcia et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 50(10), 734-743 (2015-08-15)
Microbial contamination of fresh produce can present a severe risk to public health. By conducting a rigorous survey of irrigation waters, the impacts of fecal contamination on the quality of produce could be assessed. In this study, surface waters were
Migma Dorji Tamang et al.
Antimicrobial agents and chemotherapy, 52(11), 4159-4162 (2008-08-30)
Screening of 368 consecutive nonreplicate clinical isolates of Enterobacteriaceae resistant to nalidixic acid and at least one extended-spectrum beta-lactam revealed the presence of qnrA, qnrB, and qnrS determinants, and identified novel qnrB variants, in Citrobacter freundii isolates. This study also
Stéphanie Matrat et al.
Antimicrobial agents and chemotherapy, 52(2), 745-747 (2007-12-12)
Mycobacterium leprae DNA gyrases carrying various mutations, previously described in clinical strains, were investigated for quinolone susceptibility by inhibition of supercoiling and DNA cleavage promotion. We demonstrated that the gyrA mutations leading to G89C or A91V confer fluoroquinolone resistance whereas
Intestinal Epithelial Cell Tyrosine Kinase 2 Transduces IL-22 Signals To Protect from Acute Colitis.
Eva Hainzl et al.
Journal of immunology (Baltimore, Md. : 1950), 195(10), 5011-5024 (2015-10-04)
In the intestinal tract, IL-22 activates STAT3 to promote intestinal epithelial cell (IEC) homeostasis and tissue healing. The mechanism has remained obscure, but we demonstrate that IL-22 acts via tyrosine kinase 2 (Tyk2), a member of the Jak family. Using
Jang-Gi Choi et al.
PloS one, 9(7), e102697-e102697 (2014-07-23)
Galla rhois is a commonly used traditional medicine for the treatment of pathogenic bacteria in Korea as well as in other parts of Asia. Methyl gallate (MG), a major component of Galla Rhois, exhibits strong antibacterial activity, but its mechanism
Bing Gu et al.
International journal of antimicrobial agents, 40(1), 9-17 (2012-04-10)
Shigella is becoming an increasing public health problem due to development of multiple antimicrobial resistance, frequently resulting in treatment failure. A systematic review was conducted based on a literature search of computerised databases. Random or fixed-effects models were used, based
Tamas Hatfaludi et al.
Antimicrobial agents and chemotherapy, 52(11), 4166-4171 (2008-08-30)
Two TolC homologs, PM0527 and PM1980, were identified for Pasteurella multocida. A pm0527 mutant displayed increased susceptibility to a range of chemicals, including rifampin (512-fold) and acridine orange (128-fold). A pm1980 mutant showed increased susceptibility to rifampin, ceftazidime, and vancomycin.
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