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Showing 1-30 of 151 results for "O0700000" within Papers
Weiyun Qian et al.
The Journal of clinical endocrinology and metabolism, 99(12), 4683-4689 (2014-09-19)
Oxytocin can affect energy homeostasis and has interesting potential as a metabolic disease therapeutic. We detected serum oxytocin levels in obese (OB) and type 2 diabetes mellitus (T2DM) subjects and investigated the relationships between serum oxytocin levels and glycolipid metabolism
Wensi Tao et al.
PloS one, 9(10), e110737-e110737 (2014-11-02)
Disabled-2 (Dab2) is a widely expressed endocytic adaptor that was first isolated as a 96 KDa phospho-protein, p96, involved in MAPK signal transduction. Dab2 expression is lost in several cancer types including breast cancer, and Dab2 is thought to have
Valéria Ernestânia Chaves et al.
Peptides, 45, 9-14 (2013-05-01)
The basic mechanisms that lead obesity are not fully understood; however, several peptides undoubtedly play a role in regulating body weight. Obesity, a highly complex metabolic disorder, involves central mechanisms that control food intake and energy expenditure. Previous studies have
Mercè Masana et al.
Psychoneuroendocrinology, 48, 98-110 (2014-07-08)
Understanding the molecular mechanisms by which stress is translated into changes in complex behavior may help to identify novel treatment strategies for stress-associated psychiatric disorders. The tumor suppressor gene down-regulated in renal cell carcinoma 1 (DRR1) was recently characterized as
Oxytocin: a likely underestimated risk for anaphylactic reactions in delivering women sensitized to latex.
Gennaro Liccardi et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 110(6), 465-466 (2013-05-28)
Picklu Chaudhuri et al.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 128(1), 48-52 (2014-10-04)
To evaluate whether a combination of misoprostol and oxytocin more effectively reduces blood loss during and after cesarean delivery than does oxytocin alone among women with known risk factors for postpartum hemorrhage (PPH). A prospective, randomized, double-blind, placebo-controlled trial was
A secondary analysis of a randomized placebo-controlled trial comparing the analgesic effects of oxytocin with carbetocin: postcesarean delivery morphine equivalents.
Ewa Gawecka et al.
Anesthesia and analgesia, 119(4), 1004-1004 (2014-09-19)
Ji-Woong Choi et al.
Journal of neurochemistry, 126(3), 331-337 (2013-05-21)
Oxytocin (Oxt), produced in the hypothalamic paraventricular and supraoptic nuclei for transport to and release from the posterior pituitary, was originally discovered through its role in lactation and parturition. Oxt also plays important roles in the central nervous system by
Marta Busnelli et al.
The Journal of pharmacology and experimental therapeutics, 346(2), 318-327 (2013-06-01)
The neuropeptides oxytocin (OT) and vasopressin (AVP) have been shown to play a central role in social behaviors; as a consequence, they have been recognized as potential drugs to treat neurodevelopmental and psychiatric disorders characterized by impaired social interactions. However
Reihane Seifi Moroudi et al.
Molecular biology reports, 41(12), 8019-8030 (2014-09-07)
One of the important behaviors of dogs is trainability which is affected by learning and memory genes. These kinds of the genes have not yet been identified in dogs. In the current research, these genes were found in animal models
T M Aramide et al.
Nigerian journal of clinical practice, 17(1), 10-13 (2013-12-12)
This comparative study was aimed at determining the effectiveness of oral Misoprostol compared with intravenous Ergometrine and intravenous Oxytocin in reducing vaginal bleeding following surgical evacuation for first trimester abortions. This was a single-blind placebo-controlled study in which patients with
Jannet J H Bakker et al.
The Cochrane database of systematic reviews, 2(2), CD007707-CD007707 (2013-03-02)
Induction of labour is a common intervention in obstetric practice. Traditionally, in most hospitals induction of labour with medication starts early in the morning, with the start of the working day for the day shift. In human and animal studies
Michael E McCullough et al.
Neuroscience and biobehavioral reviews, 37(8), 1485-1492 (2013-05-15)
Research on the neurobiological and behavioral effects of oxytocin (OT), as well as on its possible therapeutic applications, has intensified in the past decade. Accurate determination of peripheral OT levels is essential to reach meaningful conclusions and to motivate, support
Ageing research: Blood to blood.
Megan Scudellari
Nature, 517(7535), 426-429 (2015-01-23)
Denis J Crankshaw et al.
Life sciences, 116(1), 25-30 (2014-09-10)
Methyl palmitate is thought to cause relaxation in vascular smooth muscle by opening voltage-activated potassium channels. We have tested the hypothesis that methyl palmitate, a putative regulator from perivascular fat, is an inhibitor of the contractility of human pregnant myometrium
A Ziolkowska et al.
Polish journal of veterinary sciences, 16(2), 231-239 (2013-08-27)
Cortisol stimulates the synthesis and secretion of oxytocin (OT) from bovine granulosa and luteal cells, but the molecular mechanisms of cortisol action remain unknown. In this study, granulosa cells or luteal cells from days 1-5 and 11-15 of the oestrous
Sara Kenyon et al.
The Cochrane database of systematic reviews, 7(7), CD007201-CD007201 (2013-07-16)
A major cause of failure to achieve spontaneous vaginal birth is delay in labour due to presumed inefficient uterine action. Oxytocin is given to increase contractions and high-dose regimens may potentially increase the number of spontaneous vaginal births, but as
Oliver J Bosch
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 368(1631), 20130085-20130085 (2013-10-30)
The most significant social behaviour of the lactating mother is maternal behaviour, which comprises maternal care and maternal aggression (MA). The latter is a protective behaviour of the mother serving to defend the offspring against a potentially dangerous intruder. The
Dan-Mikael Ellingsen et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(44), 17993-17998 (2013-10-16)
Placebo analgesia is often conceptualized as a reward mechanism. However, by targeting only negative experiences, such as pain, placebo research may tell only half the story. We compared placebo improvement of painful touch (analgesia) with placebo improvement of pleasant touch
Dong Bo Li et al.
Organic letters, 15(18), 4766-4769 (2013-09-03)
New classes of thia/oxa-azaspiro[3.4]octanes are synthesized through the implementation of robust and step-economic routes. The targeted spirocycles have been designed to act as novel, multifunctional, and structurally diverse modules for drug discovery. Furthermore, enantioselective approaches to the spirocycles are reported.
Guillaume E Beranger et al.
Endocrinology, 155(4), 1340-1352 (2014-02-11)
Osteoporosis and overweight/obesity constitute major worldwide public health burdens that are associated with aging. A high proportion of women develop osteoporosis and increased intraabdominal adiposity after menopause. which leads to bone fractures and metabolic disorders. There is no efficient treatment
Akiko Katoh et al.
Journal of UOEH, 35(2), 165-171 (2013-06-19)
Oxytocin, a neurohypophyseal hormone, is synthesized in the magnocellular neurosecretory cells located in the paraventricular and supraoptic nuclei of the hypothalamus, and is secreted into the systemic blood flow from the axon terminals. It is well known that plasma oxytocin
J Li et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 27(1), 51-62 (2014-10-28)
Oxytocin plays an analgesic role in modulation of nociception and pain. Most work to date has focused on the central mechanisms of oxytocin analgesia, but little is known about whether peripheral mechanisms are also involved. The mesenteric afferent discharge was
Genichiro Sumi et al.
Journal of natural medicines, 68(3), 550-560 (2014-04-18)
We previously reported that shakuyaku-kanzo-to, a kampo medicine consisting of shakuyaku and kanzo, has an inhibitory effect on myometrial contractions in pregnant women. In this study, we evaluated the effects of kanzo, glycyrrhizin (a major component of kanzo), glycyrrhetinic acid
Drug errors--the ten commandments.
G Jackson et al.
Anaesthesia, 68(6), 648-649 (2013-05-15)
Elizabeth C Finger et al.
Neurology, 84(2), 174-181 (2014-12-17)
To determine the safety and tolerability of 3 doses of intranasal oxytocin (Syntocinon; Novartis, Bern, Switzerland) administered to patients with frontotemporal dementia (FTD). We conducted a randomized, parallel-group, double-blind, placebo-controlled study using a dose-escalation design to test 3 clinically feasible
Elizabeth A Lawson et al.
The Journal of clinical psychiatry, 74(5), e451-e457 (2013-06-14)
Anorexia nervosa, a psychiatric disorder characterized by self-induced starvation, is associated with endocrine dysfunction and comorbid anxiety and depression. Animal data suggest that oxytocin may have anxiolytic and antidepressant effects. We have reported increased postprandial oxytocin levels in women with
Chiharu Kanamori et al.
European journal of obstetrics, gynecology, and reproductive biology, 178, 142-147 (2014-05-06)
Although smoking is the most important modifiable risk factor associated with preterm delivery, the underlying mechanism by which smoking stimulates premature uterine contractions is still poorly understood. In the present study, we investigated whether cigarette smoking affects the contractile sensitivity
J D Woolley et al.
Psychoneuroendocrinology, 53, 217-222 (2015-02-01)
Olfaction plays an important role in mammalian social behavior. Olfactory deficits are common in schizophrenia and correlate with negative symptoms and low social drive. Despite their prominence and possible clinical relevance, little is understood about the pathological mechanisms underlying olfactory
Anna L MacKinnon et al.
Psychoneuroendocrinology, 48, 52-63 (2014-07-06)
The present longitudinal study examined the relations between plasma oxytocin, theory of mind, and maternal interactive behavior during the perinatal period. A community sample of women was assessed at 12-14 weeks gestation, 32-34 weeks gestation, and 7-9 weeks postpartum. Oxytocin
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