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Showing 1-30 of 222 results for "O3251" within Papers
Guillaume E Beranger et al.
Endocrinology, 155(4), 1340-1352 (2014-02-11)
Osteoporosis and overweight/obesity constitute major worldwide public health burdens that are associated with aging. A high proportion of women develop osteoporosis and increased intraabdominal adiposity after menopause. which leads to bone fractures and metabolic disorders. There is no efficient treatment
Teófilo L Reyes et al.
The journals of gerontology. Series B, Psychological sciences and social sciences, 69 Suppl 2, S229-S237 (2014-11-02)
We present the novel urine collection method used during in-home interviews of a large population representative of older adults in the United States (aged 62-91, the National Social Life, Health and Aging Project). We also present a novel assay method
Michael E McCullough et al.
Neuroscience and biobehavioral reviews, 37(8), 1485-1492 (2013-05-15)
Research on the neurobiological and behavioral effects of oxytocin (OT), as well as on its possible therapeutic applications, has intensified in the past decade. Accurate determination of peripheral OT levels is essential to reach meaningful conclusions and to motivate, support
Isabel Sospedra et al.
Journal of food science, 80(6), H1425-H1431 (2015-05-16)
Obesity prevalence in developed countries has promoted the need to identify the mechanisms involved in control of feeding and energy balance. We have tested the hypothesis that different fats present in diet composition may contribute in body weight gain and
Drug errors--the ten commandments.
G Jackson et al.
Anaesthesia, 68(6), 648-649 (2013-05-15)
Sara Kenyon et al.
The Cochrane database of systematic reviews, 7(7), CD007201-CD007201 (2013-07-16)
A major cause of failure to achieve spontaneous vaginal birth is delay in labour due to presumed inefficient uterine action. Oxytocin is given to increase contractions and high-dose regimens may potentially increase the number of spontaneous vaginal births, but as
Monika Eckstein et al.
Biological psychiatry, 78(3), 194-202 (2014-12-30)
Current neurocircuitry models of anxiety disorders posit a lack of inhibitory tone in the amygdala during acquisition of Pavlovian fear responses and deficient encoding of extinction responses in amygdala-medial prefrontal cortex circuits. Competition between these two responses often results in
Oliver J Bosch
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 368(1631), 20130085-20130085 (2013-10-30)
The most significant social behaviour of the lactating mother is maternal behaviour, which comprises maternal care and maternal aggression (MA). The latter is a protective behaviour of the mother serving to defend the offspring against a potentially dangerous intruder. The
Kimberly H Cox et al.
Psychoneuroendocrinology, 51, 271-281 (2014-12-03)
Sex differences in behavior are widespread and often caused by hormonal differences between the sexes. In addition to hormones, the composition and numbers of the sex chromosomes also affect a variety of sex differences. In humans, X-chromosome genes are implicated
Ageing research: Blood to blood.
Megan Scudellari
Nature, 517(7535), 426-429 (2015-01-23)
Jinsil Kim et al.
BMC medical genetics, 14, 77-77 (2013-07-31)
Preterm birth (PTB) is a complex disorder associated with significant neonatal mortality and morbidity and long-term adverse health consequences. Multiple lines of evidence suggest that genetic factors play an important role in its etiology. This study was designed to identify
Elisabetta Palagi et al.
PloS one, 10(11), e0142150-e0142150 (2015-11-17)
However despotic a social group may be, managing conflicts of interest is crucial to preserve group living benefits, mainly based on cooperation. In despotic groups, post-conflict management via reconciliation (the first post-conflict reunion between former opponents) can occur, even if
Dan-Mikael Ellingsen et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(44), 17993-17998 (2013-10-16)
Placebo analgesia is often conceptualized as a reward mechanism. However, by targeting only negative experiences, such as pain, placebo research may tell only half the story. We compared placebo improvement of painful touch (analgesia) with placebo improvement of pleasant touch
J Li et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 27(1), 51-62 (2014-10-28)
Oxytocin plays an analgesic role in modulation of nociception and pain. Most work to date has focused on the central mechanisms of oxytocin analgesia, but little is known about whether peripheral mechanisms are also involved. The mesenteric afferent discharge was
Rebecca Thwing Emeny et al.
Psychoneuroendocrinology, 56, 132-142 (2015-04-02)
Whether oxytocin functions as a stress hormone in older age is unknown. We investigated oxytocin levels and the perceived stress of an adverse life event in an older population-representative sample and considered the effect of a secure/insecure attachment style on
Oxytocin and behavior: evidence for effects in the brain.
Francis L Stevens et al.
The Journal of neuropsychiatry and clinical neurosciences, 25(2), 96-102 (2013-05-21)
Weiyun Qian et al.
The Journal of clinical endocrinology and metabolism, 99(12), 4683-4689 (2014-09-19)
Oxytocin can affect energy homeostasis and has interesting potential as a metabolic disease therapeutic. We detected serum oxytocin levels in obese (OB) and type 2 diabetes mellitus (T2DM) subjects and investigated the relationships between serum oxytocin levels and glycolipid metabolism
Wensi Tao et al.
PloS one, 9(10), e110737-e110737 (2014-11-02)
Disabled-2 (Dab2) is a widely expressed endocytic adaptor that was first isolated as a 96 KDa phospho-protein, p96, involved in MAPK signal transduction. Dab2 expression is lost in several cancer types including breast cancer, and Dab2 is thought to have
Denis J Crankshaw et al.
Life sciences, 116(1), 25-30 (2014-09-10)
Methyl palmitate is thought to cause relaxation in vascular smooth muscle by opening voltage-activated potassium channels. We have tested the hypothesis that methyl palmitate, a putative regulator from perivascular fat, is an inhibitor of the contractility of human pregnant myometrium
Elizabeth C Finger et al.
Neurology, 84(2), 174-181 (2014-12-17)
To determine the safety and tolerability of 3 doses of intranasal oxytocin (Syntocinon; Novartis, Bern, Switzerland) administered to patients with frontotemporal dementia (FTD). We conducted a randomized, parallel-group, double-blind, placebo-controlled study using a dose-escalation design to test 3 clinically feasible
The human gene for oxytocin-neurophysin I (OXT) is physically mapped to chromosome 20p13 by in situ hybridization.
Rao VV
Cytogenetics and Cell Genetics, 61(4), 271-273 (1992)
T M Aramide et al.
Nigerian journal of clinical practice, 17(1), 10-13 (2013-12-12)
This comparative study was aimed at determining the effectiveness of oral Misoprostol compared with intravenous Ergometrine and intravenous Oxytocin in reducing vaginal bleeding following surgical evacuation for first trimester abortions. This was a single-blind placebo-controlled study in which patients with
Valéria Ernestânia Chaves et al.
Peptides, 45, 9-14 (2013-05-01)
The basic mechanisms that lead obesity are not fully understood; however, several peptides undoubtedly play a role in regulating body weight. Obesity, a highly complex metabolic disorder, involves central mechanisms that control food intake and energy expenditure. Previous studies have
Mercè Masana et al.
Psychoneuroendocrinology, 48, 98-110 (2014-07-08)
Understanding the molecular mechanisms by which stress is translated into changes in complex behavior may help to identify novel treatment strategies for stress-associated psychiatric disorders. The tumor suppressor gene down-regulated in renal cell carcinoma 1 (DRR1) was recently characterized as
Oxytocin: a likely underestimated risk for anaphylactic reactions in delivering women sensitized to latex.
Gennaro Liccardi et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 110(6), 465-466 (2013-05-28)
Reihane Seifi Moroudi et al.
Molecular biology reports, 41(12), 8019-8030 (2014-09-07)
One of the important behaviors of dogs is trainability which is affected by learning and memory genes. These kinds of the genes have not yet been identified in dogs. In the current research, these genes were found in animal models
Queenie K Y Cheuk et al.
Hong Kong medical journal = Xianggang yi xue za zhi, 21(3), 243-250 (2015-05-23)
To evaluate the efficacy and safety of double balloon catheter for induction of labour in Chinese women with one previous caesarean section and unfavourable cervix at term. Retrospective cohort study. A regional hospital in Hong Kong. Women with previous caesarean
A secondary analysis of a randomized placebo-controlled trial comparing the analgesic effects of oxytocin with carbetocin: postcesarean delivery morphine equivalents.
Ewa Gawecka et al.
Anesthesia and analgesia, 119(4), 1004-1004 (2014-09-19)
Marta Busnelli et al.
The Journal of pharmacology and experimental therapeutics, 346(2), 318-327 (2013-06-01)
The neuropeptides oxytocin (OT) and vasopressin (AVP) have been shown to play a central role in social behaviors; as a consequence, they have been recognized as potential drugs to treat neurodevelopmental and psychiatric disorders characterized by impaired social interactions. However
Ji-Woong Choi et al.
Journal of neurochemistry, 126(3), 331-337 (2013-05-21)
Oxytocin (Oxt), produced in the hypothalamic paraventricular and supraoptic nuclei for transport to and release from the posterior pituitary, was originally discovered through its role in lactation and parturition. Oxt also plays important roles in the central nervous system by
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