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Showing 1-30 of 54 results for "O709" within Papers
Kay Marquardt et al.
International journal of pharmaceutics, 479(1), 150-158 (2014-12-30)
RNA-cleaving DNAzymes are a potential novel class of nucleic acid-based active pharmaceutical ingredients (API). However, developing an appropriate drug delivery system (DDS) that achieves high bioavailability is challenging. Especially in a dermal application, DNAzymes have to overcome physiological barriers composed
Huan-Kai Yao et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 33(7), 1093-1095 (2010-12-09)
To study the chemical constituents of Wikstroemia indica. The constituents were isolated and purified by silica gel chromatography repeatedly, and the structures were determined by spectral data and chemical envidance. Six compounds were isolated from its petroleum ether, dichloromethane, acetone
A Antonelli et al.
Nanotechnology, 21(42), 425101-425101 (2010-09-23)
Single-walled carbon nanotubes (SWNTs) due to their unique structural and physicochemical properties, have been proposed as delivery systems for a variety of diagnostic and therapeutic agents. However, SWNTs have proven difficult to solubilize in aqueous solution, limiting their use in
Laura Carreto et al.
Biophysical journal, 82(1 Pt 1), 530-540 (2001-12-26)
As a model for the epicuticular wax layer of plant cuticular membranes, we have studied the phase behavior of 1-tetradecanol and 1-octadecanol and their binary mixtures between 5 and 70 degrees C, using differential scanning calorimetry and Fourier transform infrared
Pornsak Sriamornsak et al.
AAPS PharmSciTech, 9(2), 571-576 (2008-05-07)
The purpose of this study was to prepare wax-incorporated pectin-based emulsion gel beads using a modified emulsion-gelation method. The waxes in pectin-olive oil mixtures containing a model drug, metronidazole, were hot-melted, homogenized and then extruded into calcium chloride solution. The
Xiaole Qi et al.
The Journal of pharmacy and pharmacology, 67(4), 493-500 (2014-12-17)
The aim of this study was to prepare a disintegrating gastric floating tablet composed of floating pellets coated with acrylic resin to prolong the gastric residence time and increase the oral bioavailability of famotidine. The gastric floating pellets containing famotidine
Deirdre A Costello et al.
Journal of virology, 89(1), 350-360 (2014-10-17)
Influenza A virus strains adapt to achieve successful entry into host species. Entry is mediated by the viral membrane protein hemagglutinin (HA), which triggers membrane fusion and genome release under acidic conditions in the endosome. In addition to changes in
Han-shen Zhen et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 31(8), 1154-1156 (2008-12-31)
To study on the chemical constituents from the stem of Gymnema sylvestre. The constituents were extracted by percolation with ethanol. Then the extract was separated by systemic solvent separation methods. The part of n-butanol extract was isolated and purified by
Dechuang Yuan et al.
Journal of biomaterials science. Polymer edition, 21(4), 493-505 (2010-03-18)
The purpose of this work was to develop a novel polyurethane hydrogel system for sustained drug release, which could be used as a vaginal drug-delivery vehicle. The blank polyurethane hydrogels were synthesized by a polyol oligomeric, a diisocyanate and a
W B Rizzo et al.
Journal of lipid research, 41(7), 1077-1081 (2000-07-07)
Sjögren-Larsson syndrome (SLS) is an inherited disorder associated with deficient oxidation of long-chain aliphatic alcohols. Previous studies have reported modest elevations in total (free + esterified) fatty alcohols in SLS, but free fatty alcohols have not been selectively measured, in
Sylvie Roke et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(36), 13310-13314 (2006-08-30)
We investigate the phase behavior of surface-functionalized silica colloids at both the molecular and macroscopic levels. This investigation allows us to relate collective properties such as aggregation, gelation, and aging directly to molecular interfacial behavior. By using surface-specific vibrational spectroscopy
A Convenient Metal-Free Reagent for the Generation and Capture of Trifluoromethanethiol.
Li S G and Zard S Z
Organic Letters, 15(22), 5898-5901 (2013)
X Dong et al.
Drug development and industrial pharmacy, 32(8), 973-980 (2006-09-07)
Fatty alcohols are commonly used in lipid-based drug delivery systems including parenteral emulsions and solid lipid nanoparticles (NPs). The purpose of these studies was to determine whether horse liver alcohol dehydrogenase (HLADH), a NAD-dependent enzyme, could metabolize the fatty alcohols
Milena K Bulla et al.
Photochemistry and photobiology, 91(3), 558-566 (2015-01-13)
Schinus terebinthifolius is a plant rich in phenolic compounds, which have antioxidant properties and can provide new opportunities for treatment and prevention of diseases mediated by ultraviolet radiation like photoaging and skin cancer. The aim of this study was to
Facile Access to polymeric vesicular nanostructures: Remarkable ?-end group effects in cholesterol and pyrene functional (co) polymers.
Xu J, et al.
Macromolecules, 44(2), 299-312 (2010)
Genki Akanuma et al.
FEMS microbiology letters, 339(1), 48-56 (2012-11-24)
Extracellular lipase activity from Ralstonia sp. NT80 is induced significantly by fatty alcohols such as stearyl alcohol. We found that when lipase expression was induced by stearyl alcohol, a 14-kDa protein (designated EliA) was produced concomitantly and abundantly in the
Supriya Agnihotri et al.
Natural product research, 26(23), 2266-2269 (2012-01-21)
Hydrodistilled oil obtained from the stem bark of Myrica esculenta Buch. Ham. ex D. Don (yield 0.3%) was analysed by capillary GC and GC-MS. The volatile oil consisted mainly of n-hexadecanol (25.2%), eudesmol acetate (21.9%), palmitic acid (11.6%), cis-β-caryophyllene (8.7%)
Yi Jin et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 122(11), 989-994 (2002-11-21)
Fast-disintegrating (FD) tablets containing nicorandil-loaded dry emulsions were prepared and their controlled-release properties were examined and compared with the plain FD tablets (FD tablets without dry emulsions) and commercial tablets. The dry emulsions were prepared with myristyl alcohol and stearyl
Kervin O Evans et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 153, 333-343 (2015-09-04)
Octadecyl ferulate was prepared using solid acid catalyst, monitored using Supercritical Fluid Chromatography and purified to a 42% yield. Differential scanning calorimetry measurements determined octadecyl ferulate to have melting/solidification phase transitions at 67 and 39°C, respectively. AFM imaging shows that
E Karasulu et al.
European journal of drug metabolism and pharmacokinetics, 31(4), 291-298 (2007-02-24)
The primary and secondary objectives of this study were to develop and evaluate the predictability of in vitro-in vivo correlation models for theophylline sustained release (SR) granules. Theophylline SR granules meeting the USP Drug Release Test criteria were prepared using
Szymon Bocian et al.
Talanta, 143, 35-41 (2015-06-17)
The new type of stationary bonded phases for liquid chromatography with immobilized artificial membrane properties was synthesized. Based on the modification of diol-bonded silica gel the phosphodiester stationary phases were obtained. The structures of synthesized material were confirmed by different
M D Koone et al.
Archives of dermatology, 126(11), 1485-1490 (1990-11-01)
A number of inherited disorders of cornification have been related to abnormal lipid metabolism. In the recessively inherited Sjögren-Larsson syndrome, defined by the triad of ichthyosis, mental retardation, and spasticity, fatty alcohol:NAD+ oxidoreductase deficiency has recently been reported. These patients
Preparation of thiol-ene based photo-crosslinked polymer as a potential phase change material.
Basturk E, et al.
Materials Chemistry and Physics, 177, 521-528 (2016)
Leila Hejazi et al.
Rapid communications in mass spectrometry : RCM, 29(1), 91-99 (2014-12-03)
Mass spectrometric identification of compounds in chromatography can be obtained from molecular masses from soft ionization mass spectrometry techniques such as field ionization (FI) and fragmentation patterns from hard ionization techniques such as electron ionization (EI). Simultaneous detection by EI
Andrew J Gravelle et al.
Food research international (Ottawa, Ont.), 91, 1-10 (2017-03-16)
In the present study we have characterized the influence of the polymer gelator ethylcellulose (EC) on the crystallization behavior of mixtures of stearyl alcohol and stearic acid (SOSA). The presence of EC led to a more abrupt thermo-reversible crystallization process
Amphiphilic hyperbranched polyglycerols in a new role as highly efficient multifunctional surface active stabilizers for poly (lactic/glycolic acid) nanoparticles.
Kasza G, et al.
Royal Society of Chemistry Advances, 7(8), 4348-4352 (2017)
Jörg Bauer et al.
Journal of the American Chemical Society, 127(20), 7296-7297 (2005-05-19)
Hydrophobically assisted switching phase (HASP) synthesis is a concept that allows the choice between the advantages of solid-supported chemistry and those of solution-phase synthesis. Starting from the examination of adsorption and desorption properties of hydrophobic molecules to and from reversed-phase
V P Pandey et al.
Bollettino chimico farmaceutico, 141(5), 361-366 (2002-12-17)
The present study was carried out to formulate matrix tablets of phenformin hydrochloride. Granules of phenformin HCl were prepared by using ethyl cellulose, eudragit RS 100, gum acacia, carnauba wax, stearyl alcohol, glyceryl monostearate and triethanol amine. Thus the granules
D Zhang et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 21(4), 186-187 (2003-02-06)
Seven compounds were isolated from Quercus mongolica Fisch., six (1-VI) of them were identified as fridelin (I), beta-amyrin (II), 1-octadecanol (III), beta-sitosterol (IV), daucosterol (V) and gallic acid (VI) by means of chemical, physical and spectrosopic evidiences.
Allergic contact dermatitis from stearyl alcohol in Efudix cream.
P D Yesudian et al.
Contact dermatitis, 45(5), 313-314 (2001-11-28)
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