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Showing 1-30 of 254 results for "PENNA" within Papers
Ocular syphilis characterised by severe scleritis in a patient infected with HIV.
Seung Bum Lee et al.
The Lancet. Infectious diseases, 13(11), 994-994 (2013-10-26)
Mariagrazia Perilli et al.
Antimicrobial agents and chemotherapy, 57(2), 1047-1049 (2012-11-28)
Two laboratory mutant forms, TEM-149(H240) and TEM-149(H164-H240), of the TEM-149 extended-spectrum Ī²-lactamase enzyme were constructed by site-directed mutagenesis. TEM-149(H240) and TEM-149(H164-H240) were similar in kinetic behavior, except with respect to benzylpenicillin and ceftazidime. Molecular modeling of the two mutant enzymes
J P Salanitro et al.
Applied and environmental microbiology, 32(4), 623-632 (1976-10-01)
Morphological and physiological studies were made on chicken cecal isolates of the strictly anaerobic bacterial species Gemmiger formicilis. Structural features (phase-contrast and electron microscopy) of these microorganisms indicate they (i) are highly pleomorphic, (ii) possess a trilaminar cell wall like
Eleonor G Lago et al.
Sexually transmitted diseases, 40(2), 85-94 (2013-01-18)
The aim of this study was to investigate clinical features and outcomes of children treated for congenital syphilis (CS). Infants born alive in the public sector of SĆ£o Lucas Hospital, Porto Alegre, Brazil, 1997 to 2004, whose mothers had syphilis
Li Li et al.
Drug metabolism and disposition: the biological fate of chemicals, 41(3), 659-667 (2013-01-09)
Antifolates, in particular methotrexate (MTX), have been widely used in the treatment of primary and secondary tumors of the central nervous system (CNS). Pemetrexed (PMX) is a novel antifolate that also exhibits potent antitumor activity against CNS malignancies. Studies have
Nigel Greene et al.
Chemical research in toxicology, 23(7), 1215-1222 (2010-06-18)
Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential
Sean Ekins et al.
Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17)
Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predictive in vivo, in vitro, and in silico models to identify compounds
Xizhen Jiang et al.
European journal of medicinal chemistry, 46(8), 3526-3530 (2011-05-17)
Thirteen compounds, based on benzofuran skeleton bearing aryl substituents at its C-3 position through methanone linker, were synthesized and screened for their antibacterial and antifungal activities against four bacteria Escherichia coli, Staphylococcus aureus, Methicillin-resistant S.aureus, Bacillus subtilis, and a fungus
N Steele et al.
New Zealand veterinary journal, 62(1), 38-46 (2013-09-24)
To evaluate the efficacy of nil, three or six treatments of penethamate hydriodide on successive days for treatment of subclinical mastitis on the bacteriological cure proportion and subsequent somatic cell count (SCC). Milk samples were collected from all glands of
Maria Florencia Sierra et al.
Experimental parasitology, 218, 107997-107997 (2020-09-19)
Toxocara cati is one of the causative agents of human toxocariasis. Serological methods are used for diagnosis in paratenic hosts like humans but the humoral immune response triggered by this parasite is unknown. We characterized the humoral immune response to
Lemierre's syndrome in systemic lupus erythematosus: a report of two cases.
J C RĆødgaard et al.
Scandinavian journal of rheumatology, 42(2), 167-168 (2013-01-15)
Miranda G M Kok et al.
Analytical and bioanalytical chemistry, 405(8), 2585-2594 (2013-01-15)
A recently developed capillary electrophoresis (CE)-negative-ionisation mass spectrometry (MS) method was used to profile anionic metabolites in a microbial-host co-metabolism study. Urine samples from rats receiving antibiotics (penicillin G and streptomycin sulfate) for 0, 4, or 8 days were analysed.
Congenital syphilis: the story of a greek tragedy.
Sarah Hawkes
Sexually transmitted diseases, 40(2), 95-96 (2013-01-17)
Soile Ae Pakkanen et al.
Veterinary anaesthesia and analgesia, 42(5), 527-536 (2014-12-23)
To investigate MK-467 as part of premedication in horses anaesthetized with isoflurane. Experimental, crossover study with a 14Ā day wash-out period. Seven healthy horses. The horses received either detomidine (20Ā Ī¼gĀ kg(-1) IV) and butorphanol (20Ā Ī¼gĀ kg(-1) IV) alone (DET) or with MK-467 (200Ā Ī¼gĀ kg(-1)
Jorge MartĆn et al.
Fungal genetics and biology : FG & B, 49(12), 1004-1013 (2012-10-24)
We described previously that an autoinducer molecule, identified as 1,3-diaminopropane (1,3-DAP), is secreted by Penicillium chrysogenum and Acremonium chrysogenum. Using pH-controlled fermentor cultures we have observed in this work that 1,3-DAP and spermidine clearly stimulate the biosynthesis of benzylpenicillin in
P Giesbrecht et al.
Journal of bacteriology, 174(7), 2241-2252 (1992-04-01)
Electron microscopic research into the murosomes of staphylococci has shown that the number of murosomes involved in penicillin-induced death varies depending on the experimental conditions employed. With 0.1 micrograms of penicillin G per ml, only 1 of a total of
[Meningovascular neurosyphilis with basilar artery thrombosis, a case report and literature review].
Jorge AndrƩs JimƩnez et al.
Biomedica : revista del Instituto Nacional de Salud, 32(1), 7-12 (2012-12-14)
Herein a case is described of a 54-years old patient, HIV negative, with cerebro-vascular disease by basilar artery thrombosis secondary to meningovascular neurosyphilis. Neurosyphilis is the impairment at any stage of the central nervous system by Treponema pallidum subspecies pallidum
Gregory Kaler et al.
The Journal of biological chemistry, 282(33), 23841-23853 (2007-06-08)
Organic anion transporters (OATs, SLC22) interact with a remarkably diverse array of endogenous and exogenous organic anions. However, little is known about the structural features that determine their substrate selectivity. We examined the substrate binding preferences and transport function of
Paul P Drury et al.
Neuropharmacology, 83, 62-70 (2014-04-15)
Basal ganglia injury after hypoxia-ischemia remains common in preterm infants, and is closely associated with later cerebral palsy. In the present study we tested the hypothesis that a highly selective neuronal nitric oxide synthase (nNOS) inhibitor, JI-10, would improve survival
Moritz Hertel et al.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 72(2), 338-345 (2013-09-21)
Syphilis is an infectious, usually sexually transmitted, disease caused by Treponema pallidum, subspecies pallidum. Because of the increasing prevalence in Europe during the past few years, dentists could be confronted with patients with oral manifestations of syphilis. Because oral lesions
Neurocognitive and psychiatric changes as the initial presentation of neurosyphilis.
Cecilia T Costiniuk et al.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 185(6), 499-503 (2013-02-27)
Yu-Ting Liu et al.
Journal of medical microbiology, 62(Pt 5), 794-796 (2013-02-23)
We report a case of acute purulent meningitis caused by Streptococcus sanguinis after endoscopic ligation for oesophageal variceal haemorrhage in a cirrhotic patient without preceding symptoms of meningitis. Initial treatment with flomoxef failed. The patient was cured after 20 days
Nicolas Dupin et al.
Presse medicale (Paris, France : 1983), 42(4 Pt 1), 446-453 (2013-02-19)
Syphilis is back since 2000. Early syphilis comprises primary syphilis, secondary syphilis and early latent syphilis (less than 1 year duration). During early phases of syphilis, patients are more contagious and neurologic complications are rare. Early neurosyphilis are mostly represented
Matthieu Picard et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 113(1), 75-81 (2014-05-27)
The absence of commercially available penicilloyl-polylysine (PPL) for most of the last decade severely hampered the practice of penicillin allergy evaluation because skin testing without PPL is reported to have a poor negative predictive value (NPV). To determine the safety
Xiao-Jian Han et al.
International journal of molecular medicine, 35(4), 885-892 (2015-01-28)
Percutaneous coronary intervention [PCI or percutaneous transluminal coronary angioplasty (PTCA)] has been developed into a mature interventional treatment for atherosclerotic cardiovascular disease. However, the long-term therapeutic effect is compromised by the high incidence of vascular restenosis following angioplasty, and the
William B Lo et al.
Journal of neurosurgery. Pediatrics, 11(2), 205-209 (2012-12-04)
Gemella haemolysans has long been considered a commensal in the human upper respiratory tract. Commensals are natural inhabitants on or within another organism, deriving benefit without harming or benefiting the host. Opportunistic infection of the CNS by the species is
Wei Li et al.
Biosensors & bioelectronics, 70, 304-309 (2015-04-04)
DNA methylation catalyzed by methyltransferase (MTase) plays an important role in many biological processes, including gene transcription, genomic imprinting and cellular differentiation. Herein, a simple and novel homogeneous electrochemical strategy for ultrasensitive DNA MTase activity assay has been successfully developed
Hadir A El-Mahallawy et al.
Journal of the Egyptian National Cancer Institute, 25(1), 31-35 (2013-03-19)
Appropriate antibiotic selection and timing of administration for prophylaxis are crucial to reduce the likelihood of surgical site infection (SSI) after a clean contaminated cancer surgery. Our aim is to compare the use of two prophylactic antibiotic (PA) regimens as
Vasim Ahmed et al.
Journal of biotechnology, 163(4), 419-424 (2013-01-12)
In the present study, a novel strategy was adopted to synthesize, Ī² lactamase resistant penicillin G molecules by using the unique properties of silver nanoparticles. Ascorbic acid-stabilized spherical monodispersed silver nanoparticles were prepared by a simple chemical reaction. The formation
Jizheng Dang et al.
Bioorganic & medicinal chemistry letters, 23(3), 646-649 (2012-12-27)
At pH from 5.5 to 7.6, absorptivity of 4-nitro-1-naphthol at 450 nm is over 2.1-fold of that of para-nitrophenol at 405 nm and over 9.6-fold of that of ortho-nitrophenol at 415 nm. On 4-nitro-1-naphthyl-Ī²-D-galactopyranoside at pH 7.4, catalytic efficiency of
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