PHR1039

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Showing 1-30 of 166 results for "PHR1039" within Papers

Single-dose azithromycin versus erythromycin or amoxicillin for Chlamydia trachomatis infection during pregnancy: a meta-analysis of randomised controlled trials.

Eleni Pitsouni et al.

International journal of antimicrobial agents, 30(3), 213-221 (2007-06-29)

This review aimed to compare data regarding the effectiveness and safety of azithromycin with alternative regimens in the treatment of pregnant women with Chlamydia trachomatis infection. PubMed and Scopus databases were searched to identify relevant randomised controlled trials (RCTs). The

Occurrence of veterinary antibiotics and progesterone in broiler manure and agricultural soil in Malaysia.

Yu Bin Ho et al.

The Science of the total environment, 488-489, 261-267 (2014-05-20)

Repeated applications of animal manure as fertilizer are normal agricultural practices that may release veterinary antibiotics and hormones into the environment from treated animals. Broiler manure samples and their respective manure-amended agricultural soil samples were collected in selected locations in

Macrolide resistance conferred by rRNA mutations in field isolates of Mannheimia haemolytica and Pasteurella multocida.

Anders S Olsen et al.

The Journal of antimicrobial chemotherapy, 70(2), 420-423 (2014-09-28)

To determine how resistance to macrolides is conferred in field isolates of Pasteurella multocida and Mannheimia haemolytica that lack previously identified resistance determinants for rRNA methylation, efflux and macrolide-modifying enzymes. Isolates of P. multocida and M. haemolytica identified as being

Monitoring and removal of residual phthalate esters and pharmaceuticals in the drinking water of Kaohsiung City, Taiwan.

Gordon C C Yang et al.

Journal of hazardous materials, 277, 53-61 (2014-04-08)

This study monitored the occurrence and removal efficiencies of 8 phthalate esters (PAEs) and 13 pharmaceuticals present in the drinking water of Kaohsiung City, Taiwan. The simultaneous electrocoagulation and electrofiltration (EC/EF) process was used to remove the contaminants. To this

Geographic and temporal trends in antimicrobial nonsusceptibility in Streptococcus pneumoniae in the post-vaccine era in the United States.

Ruth Link-Gelles et al.

The Journal of infectious diseases, 208(8), 1266-1273 (2013-07-16)

We examined whether observed increases in antibiotic nonsusceptible nonvaccine serotypes after introduction of pneumococcal conjugate vaccine in the United States in 2000 were driven primarily by vaccine or antibiotic use. Using active surveillance data, we evaluated geographic and temporal differences

Effects of erythromycin and rifampicin on immunomodulatory gene expression and cellular function in human polymorphonuclear leukocytes.

Xiaoqin Mu et al.

Chemotherapy, 59(6), 395-401 (2014-05-24)

We investigated the effects of two antibiotics, erythromycin and rifampicin, on the immunomodulatory gene expression and cellular function of human polymorphonuclear leukocytes (PMNs). We used real-time quantitative PCR to examine the expression of immunomodulatory genes. The production of reactive oxygen

Fluorimetric determination of erythromycin and erythromycin ethylsuccinate in serum by a high-performance liquid chromatographic post-column, on-stream derivatization and extraction method

Tsuji K

Journal of Chromatography A, 158, 337-348 (1978)

Nasopharyngeal carriage of Streptococcus pneumoniae in Romanian children before the introduction of the pneumococcal conjugated vaccination into the national immunization programme: a national, multi-centre, cross-sectional observational study.

Monica Luminos et al.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 29, 169-173 (2014-12-03)

We analysed the distribution of vaccine and non-vaccine Streptococcus pneumoniae serotypes and the antimicrobial susceptibility of pneumococcal strains isolated from healthy Romanian children. A multi-centre cross-sectional study was performed in four counties to evaluate carried strains of S. pneumoniae isolated

Role of Lactobacillus reuteri cell and mucus-binding protein A (CmbA) in adhesion to intestinal epithelial cells and mucus in vitro.

Hanne Jensen et al.

Microbiology (Reading, England), 160(Pt 4), 671-681 (2014-01-30)

Lactobacillus reuteri, a symbiotic inhabitant of the gastrointestinal tract in humans and animals, is marketed as a probiotic. The ability to adhere to intestinal epithelial cells and mucus is an interesting property with regard to probiotic features such as colonization

Effect of long-term, low-dose erythromycin on pulmonary exacerbations among patients with non-cystic fibrosis bronchiectasis: the BLESS randomized controlled trial.

David J Serisier et al.

JAMA, 309(12), 1260-1267 (2013-03-28)

Macrolide antibiotics such as erythromycin may improve clinical outcomes in non-cystic fibrosis (CF) bronchiectasis, although associated risks of macrolide resistance are poorly defined. To evaluate the clinical efficacy and antimicrobial resistance cost of low-dose erythromycin given for 12 months to

In vitro metabolism and stability of the actinide chelating agent 3,4,3-LI(1,2-HOPO).

Taylor A Choi et al.

Journal of pharmaceutical sciences, 104(5), 1832-1838 (2015-03-03)

The hydroxypyridinonate ligand 3,4,3-LI(1,2-HOPO) is currently under development for radionuclide chelation therapy. The preclinical characterization of this highly promising ligand comprised the evaluation of its in vitro properties, including microsomal, plasma, and gastrointestinal fluid stability, cytochrome P450 inhibition, plasma protein

Effect of betamethasone in combination with antibiotics on gram positive and gram negative bacteria.

M Artini et al.

International journal of immunopathology and pharmacology, 27(4), 675-682 (2015-01-13)

Betamethasone is an anti-inflammatory steroid drug used in cases of anaphylactic and allergic reactions, of Alzheimer and Addison diseases and in soft tissue injuries. It modulates gene expression for anti-inflammatory activity suppressing the immune system response. This latter effect might

An unusual cause of persistent postpartum vaginal discharge.

Natasha Parrott et al.

International journal of STD & AIDS, 24(10), 840-841 (2013-08-24)

We describe the case of a 27-year-old woman with a three-month history of persistent green vaginal discharge following vaginal delivery of her first child. Group C β-haemolytic streptococcus was ultimately isolated, which appears to be an uncommon cause of this

Development of a novel genetically modified bioluminescent-bacteria-based assay for detection of fluoroquinolones in animal-derived foods.

Guyue Cheng et al.

Analytical and bioanalytical chemistry, 406(30), 7899-7910 (2014-10-31)

Fluoroquinolones (FQNs) are broad-spectrum antibacterial agents widely used in animal husbandry and aquaculture. The residues and antimicrobial resistance of such antibiotics are a major public health concern. To realize multianalyte detection of FQN residues, a genetically modified bacterium, Escherichia coli

Influence of dTMP on the phenotypic appearance and intracellular persistence of Staphylococcus aureus.

Johannes Zander et al.

Infection and immunity, 76(4), 1333-1339 (2007-12-28)

Thymidine-dependent small-colony variants (SCVs) of Staphylococcus aureus are frequently associated with persistent and recurrent infections in cystic fibrosis patients. The phenotypic appearance of S. aureus SCVs or normal-colony variants (NCVs) is postulated to be affected by the intracellular amount of

Combined use of liquid chromatography with mass spectrometry and nuclear magnetic resonance for the identification of degradation compounds in an erythromycin formulation

Pendela M, et al.

Analytical and Bioanalytical Chemistry, 402(2), 781-790 (2012)

Two cases of corneal abrasions in children exposed to liquid detergent capsules.

Olivier Lasnier et al.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 48(2), e29-e30 (2013-04-09)

Predicting drug-drug interactions involving multiple mechanisms using physiologically based pharmacokinetic modeling: a case study with ruxolitinib.

J G Shi et al.

Clinical pharmacology and therapeutics, 97(2), 177-185 (2015-02-12)

Physiologically based pharmacokinetic modeling was applied to characterize the potential drug-drug interactions for ruxolitinib. A ruxolitinib physiologically based pharmacokinetic model was constructed using all baseline PK data in healthy subjects, and verified by retrospective predictions of observed drug-drug interactions with

Erythromycin as a prokinetic agent: risk factors.

S Berthet et al.

Journal of visceral surgery, 147(2), e13-e18 (2010-07-27)

Erythromycin (ER) is an antibiotic with prokinetic activity. This property has led to its clinical use to improve gastric emptying in patients with gastroparesis. Several papers have reported the effectiveness of ER in such patients; however few of these studies

Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials.

Shoba Theivanayagam et al.

Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association, 19(5), 205-210 (2013-09-21)

Erythromycin infusion before endoscopy in upper gastrointestinal bleeding (UGIB) has been hypothesized to aid in visualization and reduce the need for second-look endoscopy; however, the results have been controversial. To evaluate further, we performed a meta-analysis comparing the efficacy of

Evaluation of the HC-04 cell line as an in vitro model for mechanistic assessment of changes in hepatic cytochrome P450 3A during adenovirus infection.

Piyanuch Wonganan et al.

Drug metabolism and disposition: the biological fate of chemicals, 42(7), 1191-1201 (2014-04-26)

HC-04 cells were evaluated as an in vitro model for mechanistic study of changes in the function of hepatic CYP3A during virus infection. Similar to in vivo observations, infection with a first generation recombinant adenovirus significantly inhibited CYP3A4 catalytic activity

Synthesis and antibacterial properties of pyrimidine derivatives.

Jerzy Cieplik et al.

Acta poloniae pharmaceutica, 72(1), 53-64 (2015-04-09)

In this study, a series of syntheses was conducted on the pyrimidine system, obtaining bisulfite carboxyl derivatives 4 and hydroxy derivatives 5. In addition, a series of syntheses were carried out as a result of which both alkyl and aromatic

High-performance thin-layer chromatography screening of multi class antibiotics in animal food by bioluminescent bioautography and electrospray ionization mass spectrometry.

Yisheng Chen et al.

Journal of chromatography. A, 1356, 249-257 (2014-07-13)

The world-wide usage and partly abuse of veterinary antibiotics resulted in a pressing need to control residues in animal-derived foods. Large-scale screening for residues of antibiotics is typically performed by microbial agar diffusion tests. This work employing high-performance thin-layer chromatography

Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase.

X Zou et al.

Prikladnaia biokhimiia i mikrobiologiia, 49(2), 190-196 (2013-06-26)

The physiology of feeding ammonium sulphate in erythromycin biosynthesis phase of Saccharopolyspora erythraea on the regulation of erythromycin A (Er-A) biosynthesis was investigated in 50 L fermenter. At an optimal feeding ammonium sulphate rate of 0.03 g/L per h, the

A novel erythromycin resistance plasmid from Bacillus sp. strain HS24, isolated from the marine sponge Haliclona simulans.

Teresa M Barbosa et al.

PloS one, 9(12), e115583-e115583 (2014-12-31)

A better understanding of the origin and natural reservoirs of resistance determinants is fundamental to efficiently tackle antibiotic resistance. This paper reports the identification of a novel 5.8 kb erythromycin resistance plasmid, from Bacillus sp. HS24 isolated from the marine

Population biology of intestinal enterococcus isolates from hospitalized and nonhospitalized individuals in different age groups.

Ana P Tedim et al.

Applied and environmental microbiology, 81(5), 1820-1831 (2014-12-31)

The diversity of enterococcal populations from fecal samples from hospitalized (n = 133) and nonhospitalized individuals (n = 173) of different age groups (group I, ages 0 to 19 years; group II, ages 20 to 59 years; group III, ages

Characterization of cefalexin degradation capabilities of two Pseudomonas strains isolated from activated sludge.

Bokun Lin et al.

Journal of hazardous materials, 282, 158-164 (2014-07-30)

Pharmaceuticals have recently been regarded as contaminants of emerging concern. To date, there is limited knowledge about antibiotic-degrading microorganisms in conventional activated sludge treatment systems and their characteristics toward antibiotic degradation especially in the presence of a pharmaceutical mixture. As

The formulation and stability of erythromycin-benzoyl peroxide in a topical gel

Vermeulen B, et al.

International Journal of Pharmaceutics, 178(1), 137-141 (1999)

Biosynthesis of 8-hydroxyquinoline-2-carboxylic acid, an iron chelator from the gut of the lepidopteran Spodoptera littoralis.

Jelena Pesek et al.

Organic & biomolecular chemistry, 13(1), 178-184 (2014-10-31)

In the regurgitate (foregut content) of Spodoptera larvae we found high concentrations (0.5-5 mM) of 8-hydroxyquinoline-2-carboxylic acid (8-HQA). In a survey of different lepidopteran species, this compound was only detected in species belonging to the family of Noctuidae. 8-HQA was

What is the role of antibiotic-containing cement in total knee arthroplasty?

Donald W Roberts

The Journal of bone and joint surgery. American volume, 95(9), e62-e62 (2013-05-03)

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